Horizontal, undulating, and multilateral wells are relatively new alternatives in field development because they can increase the productivity per well and reduce the cost of field development. Because the feasibility of these wells may not be valid in some reservoirs, well performance should be verified before making decisions. Undulation is usually associated to horizontal wells with some degrees. Existing inflow performance models do not account for the undulation of the well, which can cause significant error and economic loss. Moreover, some of the inflow models ignore pressure drop along the lateral, which is definitely not true in high production and long lateral wells. The inflow performance models of horizontal, undulating, and multilateral wells are developed in this study. The models can be divided into two main categories: the closed form model and the line source model. The closed form model applies for relatively low vertical permeability formations for the single-phase system and twophase system. The model is flexible and easy to apply with reasonable accuracy. The line source model does not have any restrictions with permeability. The model applies for single-phase system. The model is very accurate and easy to use. Both models can be applied to various well trajectories with realizable accuracy. As a result of this study, the well performance of unconventional well trajectories can be predicted and optimized.

O envelhecimento é um processo inexorável, porém a redução gradativa da capacidade do organismo está bastante ligada com os hábitos do estilo de vida e a fatores genéticos. Polimorfismos nos genes que codificam a enzima conversora de angiotensina (ECA) e a proteína alfa-actinina 3 (ACTN3) podem resultar em mudanças na aptidão física. Já o treinamento físico tem sido utilizado como uma ferramenta não farmacológica na prevenção primária em saúde. Por fim, a periodização deste treinamento busca ser um meio sistemático de planejar e organizar o treinamento de modo a torná-lo mais eficiente. Não há na literatura estudos com a periodização ou com os genótipos da ECA e ACT3 associados ao treinamento combinado. Nesse contexto, o objetivo desse estudo foi avaliar diferentes modelos de periodização do treinamento no exercício físico combinado em variáveis de saúde e comparar a magnitude da resposta em indivíduos com diferentes características genéticas em relação aos genes ECA e ACTN3. Após três semanas de adaptação, 54 mulheres com idade entre 50-75 anos foram randomicamente divididas nos modelos de treinamento a) não periodizado (NP), b) periodização não linear (NL) ou c) periodização não linear flexível (NLF). Para os valores pré e pós 12 semanas de treinamento, aptidão aeróbia (consumo máximo de oxigênio [VO2 pico] e teste de caminhada de seis minutos) e força muscular (1 RM no supino e leg press) foram medidas. A genotipagem da ECA foi feita por PCR convencional e a ACTN3 por PCR em tempo real. Os resultados mostraram que a força máxima foi aumentada estatisticamente no supino (effect size [ES] de 1,18 em PNL e 1,22 em PNLF] e leg press (ES de 0,92 em PNL e 0,98 em PNLF) nos grupos PNL e PNLF. No teste de caminhada de seis minutos, a magnitude da aptidão aeróbica melhorou em todos os grupos (ES de 1,02 em NP, 1,33 em PNL e 0,54 em PNLF). Para o gene da ECA, houve uma diferença estatística entre os grupos do pré para o pós no supino (ID/DD: 18,6%; II: 8,3%). Para o gene da ACTN3, houve diferença estatística do pré para o pós dentro do grupo no supino (CC/CT: 17,4%; TT: 6,9%) e leg press (CC/CT: 12,3%; TT: 7,5%) apenas no grupo CC/CT. Em conclusão, o presente estudo mostrou que os modelos periodizados foram capazes de induzir melhorias significativas na força muscular em mulheres pós menopausa fisicamente ativas. Além disso, os genótipos ID/DD do gene da ECA e CC/CT do gene da ACTN3 melhor efeito na força muscular no treinamento combinado. / The aging is an inexorable process, but the gradual reduction of the capacity in the organism is related with lifestyle habits and genetic factors. Polymorphisms in genes encoding both angiotensin converting enzyme (ACE) and alpha-actinin 3 protein (ACTN3) may result in changes in physical fitness. Physical training has been used as a non-pharmacological tool in primary health prevention. Finally, the periodization training is a systematic means of planning and organizing training to do it more efficient. There are no studies in the literature with periodization or with ACT and ACT3 genotypes associated to combined training. In this context, the objective of this study was to evaluate different models of periodization training in combined exercise training in health variables and to compare the magnitude of the response in individuals with different genetic characteristics in relation to the ACE and ACTN3 genes. After three weeks of adaptation, 54 women aged 50-75 years were randomly assigned to a) nonperiodization (NP), b) non-linear periodization (NLP) or c) flexible non-linear periodization (FNLP). At baseline and after 12 weeks, aerobic fitness (peak oxygen uptake [VO2peak] and six-minute walk test) and maximal muscle strength (1 RM bench press and leg press) were measured. The ACE genotyping was performed trough conventional PCR and ACTN3 by real-time PCR. The results showed that the magnitude of the maximal strength statistically increased in the bench press [effect size (ES) of 1.18 in NLP and 1.22 in FNLP] and leg press (ES of 0.92 in NLP and 0.98 in FNLP) only in the periodized groups. In six-minute walk test, the magnitude of the aerobic fitness improved in all groups (ES of 1.02 in NP, 1.33 in UP and 0.54 in FNLP). In conclusion, the present study showed that periodized models could induce significant improvements on muscle strength in active postmenopausal women. In the ACE gene, there was a statistical difference between the groups from pre to post supine (ID / DD: 18.6%, II: 8.3%). For the ACTN3 gene, there was a statistical difference between the pre and post within the group in the bench press (CC/CT: 17,4%; TT: 6,9%) and leg press (CC/CT: 12,3%; TT: 7,5%) only in the CC/CT group. In conclusion, the present study showed that periodized models could induce significant improvements on muscle strength in active postmenopausal women. In addition, the genotypes ID / DD of the ECA and CC / CT gene of ACTN3 gene had a better effect to muscle strength.

O envelhecimento é um processo inexorável, porém a redução gradativa da capacidade do organismo está bastante ligada com os hábitos do estilo de vida e a fatores genéticos. Polimorfismos nos genes que codificam a enzima conversora de angiotensina (ECA) e a proteína alfa-actinina 3 (ACTN3) podem resultar em mudanças na aptidão física. Já o treinamento físico tem sido utilizado como uma ferramenta não farmacológica na prevenção primária em saúde. Por fim, a periodização deste treinamento busca ser um meio sistemático de planejar e organizar o treinamento de modo a torná-lo mais eficiente. Não há na literatura estudos com a periodização ou com os genótipos da ECA e ACT3 associados ao treinamento combinado. Nesse contexto, o objetivo desse estudo foi avaliar diferentes modelos de periodização do treinamento no exercício físico combinado em variáveis de saúde e comparar a magnitude da resposta em indivíduos com diferentes características genéticas em relação aos genes ECA e ACTN3. Após três semanas de adaptação, 54 mulheres com idade entre 50-75 anos foram randomicamente divididas nos modelos de treinamento a) não periodizado (NP), b) periodização não linear (NL) ou c) periodização não linear flexível (NLF). Para os valores pré e pós 12 semanas de treinamento, aptidão aeróbia (consumo máximo de oxigênio [VO2 pico] e teste de caminhada de seis minutos) e força muscular (1 RM no supino e leg press) foram medidas. A genotipagem da ECA foi feita por PCR convencional e a ACTN3 por PCR em tempo real. Os resultados mostraram que a força máxima foi aumentada estatisticamente no supino (effect size [ES] de 1,18 em PNL e 1,22 em PNLF] e leg press (ES de 0,92 em PNL e 0,98 em PNLF) nos grupos PNL e PNLF. No teste de caminhada de seis minutos, a magnitude da aptidão aeróbica melhorou em todos os grupos (ES de 1,02 em NP, 1,33 em PNL e 0,54 em PNLF). Para o gene da ECA, houve uma diferença estatística entre os grupos do pré para o pós no supino (ID/DD: 18,6%; II: 8,3%). Para o gene da ACTN3, houve diferença estatística do pré para o pós dentro do grupo no supino (CC/CT: 17,4%; TT: 6,9%) e leg press (CC/CT: 12,3%; TT: 7,5%) apenas no grupo CC/CT. Em conclusão, o presente estudo mostrou que os modelos periodizados foram capazes de induzir melhorias significativas na força muscular em mulheres pós menopausa fisicamente ativas. Além disso, os genótipos ID/DD do gene da ECA e CC/CT do gene da ACTN3 melhor efeito na força muscular no treinamento combinado. / The aging is an inexorable process, but the gradual reduction of the capacity in the organism is related with lifestyle habits and genetic factors. Polymorphisms in genes encoding both angiotensin converting enzyme (ACE) and alpha-actinin 3 protein (ACTN3) may result in changes in physical fitness. Physical training has been used as a non-pharmacological tool in primary health prevention. Finally, the periodization training is a systematic means of planning and organizing training to do it more efficient. There are no studies in the literature with periodization or with ACT and ACT3 genotypes associated to combined training. In this context, the objective of this study was to evaluate different models of periodization training in combined exercise training in health variables and to compare the magnitude of the response in individuals with different genetic characteristics in relation to the ACE and ACTN3 genes. After three weeks of adaptation, 54 women aged 50-75 years were randomly assigned to a) nonperiodization (NP), b) non-linear periodization (NLP) or c) flexible non-linear periodization (FNLP). At baseline and after 12 weeks, aerobic fitness (peak oxygen uptake [VO2peak] and six-minute walk test) and maximal muscle strength (1 RM bench press and leg press) were measured. The ACE genotyping was performed trough conventional PCR and ACTN3 by real-time PCR. The results showed that the magnitude of the maximal strength statistically increased in the bench press [effect size (ES) of 1.18 in NLP and 1.22 in FNLP] and leg press (ES of 0.92 in NLP and 0.98 in FNLP) only in the periodized groups. In six-minute walk test, the magnitude of the aerobic fitness improved in all groups (ES of 1.02 in NP, 1.33 in UP and 0.54 in FNLP). In conclusion, the present study showed that periodized models could induce significant improvements on muscle strength in active postmenopausal women. In the ACE gene, there was a statistical difference between the groups from pre to post supine (ID / DD: 18.6%, II: 8.3%). For the ACTN3 gene, there was a statistical difference between the pre and post within the group in the bench press (CC/CT: 17,4%; TT: 6,9%) and leg press (CC/CT: 12,3%; TT: 7,5%) only in the CC/CT group. In conclusion, the present study showed that periodized models could induce significant improvements on muscle strength in active postmenopausal women. In addition, the genotypes ID / DD of the ECA and CC / CT gene of ACTN3 gene had a better effect to muscle strength.

A field experiment initiated in spring 2012 was established to assess the relationships between grain yield, grain protein and soil properties including elevation, electrical conductivity, pH, and organic carbon in an undulating landscape. Grain protein can reflect the balance of nitrogen (N) relative to other yield limiting factors. The objective of this study was to 1) assess relationships between soil properties, crop yield and protein content in an undulating landscape in south-central Saskatchewan, and 2) determine feasibility of using protein content along with yield and soil data in identifying variable rate N application zones. In 2012, wheat, canola and peas were seeded. Soil samples and harvest measurements were taken from two transects in each field area. Wheat, canola and pea yields ranged from 882 to 2554, 1143 to 2342, and 839 to 3122 kg ha-1 respectively, while protein content for wheat, canola and peas ranged from 10.5 to 14.4, 14.2 to 20.6 and 14.5 to 17.7 percent respectively. Protein in wheat was positively correlated with pH in the 30-60 cm depth and negatively correlated with electrical conductivity in the 30-60 cm depth. Protein in canola was positively correlated with organic carbon in the 0-30 cm depth. Wheat yield was positively correlated with organic carbon in the 0-30 cm depth. Pea yield was negatively correlated with electrical conductivity in the 0-30 and 30-60 cm depths. In spring 2013, wheat was seeded on canola and pea stubble and canola seeded on wheat stubble with varied N rates on one side of each transect with a constant N rate on the other. Greater mean yields were observed from the varied N rate versus the control in the canola-wheat (3163 vs 2256 kg ha-1) and wheat-pea (4716 vs 4155 kg ha-1) rotations. A negative yield from the varied N rate versus the control was observed in the wheat-canola (2216 vs 3012 kg ha-1) rotation. However, these yield differences were not significant at p < 0.05.

[Truncated abstract] Resistance training is increasingly popular for improving strength qualities such as hypertrophy, maximal strength, endurance and power. Although many resistancetraining programmes now adhere to the concept of periodisation, the number of studies examining its structure and design are few, and there are just a handful of studies that have examined periodised training for the maintenance of strength and power. Even rarer, are periodised resistance-training studies that utilise female subjects. Previous studies have compared non-periodised training regimens such as Progressive Resistance Exercise (PRE), and the two main models of periodisation, Linear Periodisation (LP) and Undulating Periodisation (UP). Results are inconclusive as to whether the efficacy of the periodised training programmes were due to the manipulation of training variables such as volume and intensity, or that training programmes with higher doses of volume induced better training responses. However, to make effective comparisons between training programmes, the training volume or workload (total load lifted x total repetitions) and training intensity have to be equated between the groups under examination. While the intensities (percentage of one-repetition maximum, 1 RM) for improving strength qualities such as hypertrophy and maximal strength have general consensus among resistance-training practitioners, there exists disagreement over the intensity that should be used during the training of power. Thus, it is important to first identify the load for power training before comparisons can be made between LP and UP programmes using equal training volumes. ... The final study found that adhering to two UP maintenance training programmes with equalised volumes and intensities twice a week increased upper-body strength and maintained lower-body strength adequately across a 3-wk phase. The results from these studies support previous results that suggest training programmes with higher workloads and repetitions produce superior strength and power adaptations, and it is not specifically the variation of training volume and intensity within a periodised programme that improves strength qualities. Thus, both periodised programmes used in this thesis can be recommended for untrained and moderatelytrained women as both LP and UP were found to be similarly effective for increasing upper- and lower-body hypertrophy, strength and power.

Dans cette thèse, nous avons étudié la simulation numérique des phénomènes d’interaction fluide-structure (IFS) par la méthode des éléments finis pour un fluide incompressible et non visqueux en interaction avec une structure flexible. Les modèles numériques développés sont basé sur une approche d’IFS partitionnée. Une amélioration basée sur une compensation des effets de massé ajoutée est proposée au cours de la thèse afin d’assurer la convergence et la stabilité du schéma de couplage partitionné indépendamment de la densité du fluide impliqué. L’approche corrective nécessite une estimation de la matrice de masse ajoutée et demande une légère modification de l’algorithme itératif. Les méthodes proposées ont été validées sur les cas académiques en comparaison avec les solutions analytiques et sont appliqués au cas d’une nouvelle conception de pompe pour tout type de fluides (gaz, liquides, fluide chargé…), en vue d’affiner la compréhension de son fonctionnement et ainsi mieux la caractériser. Les méthodes ainsi que les validations sont publiées sur un article qui a été accepté par le revue scientifique « Computers & Fluids ». Une présentation orale a effectuée pendant la conférence internationale ACE-X2012 à Istanbul et une autre a été accepté par la conférence nationale CSMA-2013 à Giens. / The numerical simulation of fluid-structure interaction (FSI) by the finite element method has been studied in the context of an incompressible and inviscid flow interacting with a very flexible structure.The numerical models developed in this work are based on a partitioned FSI approach. An improvement based on a compensation of the added-mass effect is proposed during the PhD research in order to ensure the convergence and the stability of the partitioned coupling scheme for all fluids regardless of its density. This simple correction requires to estimate the added-mass matrix and to modify slightly the iterative algorithm.The proposed methods were validated by comparing with analytical solutions for several academic cases and are applied to a novel pumping technology, which is applicable to all kinds of fluid (gas, liquid, slurry...). The main objective is to provide a better understanding about its operations and to improve the designing of pump. The methods and the validation cases are published in an article which has been accepted by the scientific review Computers & Fluids. They were also presented during the international conference ACE-X2012 in Istanbul and have been accepted and scheduled for oral presentation during the national conference CSMA-2013 in Giens.

No description available.

Die experimentellen Untersuchungen zur Strömungs-Struktur-Interaktion kommen zu folgenden Ergebnissen. Die als entrainment bezeichnete Verhaltensweise von Fischen kann durch den gezielten Ausgleich von Auftriebs-, Widerstands- und einer erstmals nachgewiesenen Saugkraft und der damit verbundenen Reduzierung der lokomotorischen Energie erklärt werden. Des Weiteren zeigen die Experimente an einer wellenförmig bewegten Oberfläche, dass die Strömung an einem Wellenberg zyklisch zwischen laminarem und turbulentem Regime wechselt und dass diese Oszillation zur Reduzierung des Form- und Gesamtwiderstandes der geschleppten Oberfläche führt. Dünne, flexible Häutchen hairy flaps an der Rückseite eines Zylinders führen zu einer Änderung der Struktur der Wirbelablösung an diesem. Dadurch wird sowohl die auf den Zylinder wirkende Auftriebskraft als auch die Widerstandskraft um bis zu 65% reduziert. Für die Interaktion zwischen der Strömung um zwei hintereinander positionierte elastische Zylinder und ihrer Kinematik konnte die Synchronisierung (lock-in) ihrer Bewegung mit einer verbundenen Zerstörung der Wirbelstraße hinter dem zweiten Zylinder gezeigt werden. / The experimental investigations presented herein explain the behavioural adaptation of fish called entrainment for the first time. The results confirm a balance of lift-, drag- and a suction-force, explaining the reduction of locomotive energy. Furthermore, flow measurements around an undulating membrane affirm an oscillation between laminar and turbulent flow over one period of the motion and that this oscillation decreases the pressure- and drag-force of the towed membrane. Experiments on thin and flexible flaps attached at the lee-side of a cylinder, show that the flaps alter the natural vortex separation cycle in such a way that the vortices do not shed in a staggered side-by-side arrangement but in line in a row with the cylinder wake axis. Thus, flow fluctuations are reduced by 42% in stream-wise - and 35% in transversal direction at best, compared to a reference case without hairy-flaps. Finally, investigations on the flow around and on the kinematics of two flexible cylinders in a tandem arrangement demonstrate a synchronisation of their motion (lock-in), resulting in the destruction of the vortex-street behind the second cylinder.

Die experimentellen Untersuchungen zur Strömungs-Struktur-Interaktion kommen zu folgenden Ergebnissen. Die als entrainment bezeichnete Verhaltensweise von Fischen kann durch den gezielten Ausgleich von Auftriebs-, Widerstands- und einer erstmals nachgewiesenen Saugkraft und der damit verbundenen Reduzierung der lokomotorischen Energie erklärt werden. Des Weiteren zeigen die Experimente an einer wellenförmig bewegten Oberfläche, dass die Strömung an einem Wellenberg zyklisch zwischen laminarem und turbulentem Regime wechselt und dass diese Oszillation zur Reduzierung des Form- und Gesamtwiderstandes der geschleppten Oberfläche führt. Dünne, flexible Häutchen hairy flaps an der Rückseite eines Zylinders führen zu einer Änderung der Struktur der Wirbelablösung an diesem. Dadurch wird sowohl die auf den Zylinder wirkende Auftriebskraft als auch die Widerstandskraft um bis zu 65% reduziert. Für die Interaktion zwischen der Strömung um zwei hintereinander positionierte elastische Zylinder und ihrer Kinematik konnte die Synchronisierung (lock-in) ihrer Bewegung mit einer verbundenen Zerstörung der Wirbelstraße hinter dem zweiten Zylinder gezeigt werden.:Zusammenfassung 1 Conclusions 7 1. Einleitung und Zielsetzung 11 2. Messtechnische Grundlagen 17 2.1. Klassische Particle Image Velocimetry 18 2.2. Scanning Particle Image Velocimetry 20 2.3. Mirror Particle Tracking Velocimetry 21 2.4. Druckberechnung 35 3. Hydrodynamisches Modell des entrainments 37 3.1. Stand der Forschung 38 3.2. Experimenteller Aufbau 42 3.3. Ergebnisse 44 3.4. Zusammenfassung 51 4. Undulatorisch bewegte Oberflächen 53 4.1. Stand der Forschung 54 4.2. Mechanisches Modell 57 4.3. Experimenteller Aufbau 61 4.4. Ergebnisse 65 4.5. Zusammenfassung 74 5. Selbstadaptive elastische Klappen - hairy flaps 77 5.1. Stand der Forschung 78 5.2. Experimenteller Aufbau 82 5.3. Ergebnisse 86 5.4. Zusammenfassung 107 6. Umströmung stumpfer elastischer Körper 109 6.1. Stand der Forschung 110 6.2. Experimenteller Aufbau 116 6.3. Ergebnisse 120 6.4. Zusammenfassung 128 7. Ausblick 131 Abbildungsverzeichnis 135 Tabellenverzeichnis 141 Symbolverzeichnis 142 Literaturverzeichnis 146 A. Anhang 155 / The experimental investigations presented herein explain the behavioural adaptation of fish called entrainment for the first time. The results confirm a balance of lift-, drag- and a suction-force, explaining the reduction of locomotive energy. Furthermore, flow measurements around an undulating membrane affirm an oscillation between laminar and turbulent flow over one period of the motion and that this oscillation decreases the pressure- and drag-force of the towed membrane. Experiments on thin and flexible flaps attached at the lee-side of a cylinder, show that the flaps alter the natural vortex separation cycle in such a way that the vortices do not shed in a staggered side-by-side arrangement but in line in a row with the cylinder wake axis. Thus, flow fluctuations are reduced by 42% in stream-wise - and 35% in transversal direction at best, compared to a reference case without hairy-flaps. Finally, investigations on the flow around and on the kinematics of two flexible cylinders in a tandem arrangement demonstrate a synchronisation of their motion (lock-in), resulting in the destruction of the vortex-street behind the second cylinder.:Zusammenfassung 1 Conclusions 7 1. Einleitung und Zielsetzung 11 2. Messtechnische Grundlagen 17 2.1. Klassische Particle Image Velocimetry 18 2.2. Scanning Particle Image Velocimetry 20 2.3. Mirror Particle Tracking Velocimetry 21 2.4. Druckberechnung 35 3. Hydrodynamisches Modell des entrainments 37 3.1. Stand der Forschung 38 3.2. Experimenteller Aufbau 42 3.3. Ergebnisse 44 3.4. Zusammenfassung 51 4. Undulatorisch bewegte Oberflächen 53 4.1. Stand der Forschung 54 4.2. Mechanisches Modell 57 4.3. Experimenteller Aufbau 61 4.4. Ergebnisse 65 4.5. Zusammenfassung 74 5. Selbstadaptive elastische Klappen - hairy flaps 77 5.1. Stand der Forschung 78 5.2. Experimenteller Aufbau 82 5.3. Ergebnisse 86 5.4. Zusammenfassung 107 6. Umströmung stumpfer elastischer Körper 109 6.1. Stand der Forschung 110 6.2. Experimenteller Aufbau 116 6.3. Ergebnisse 120 6.4. Zusammenfassung 128 7. Ausblick 131 Abbildungsverzeichnis 135 Tabellenverzeichnis 141 Symbolverzeichnis 142 Literaturverzeichnis 146 A. Anhang 155