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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Os efeitos do balan?o h?drico positivo em lactentes menores de um ano com bronquiolite viral aguda submetidos ? ventila??o mec?nica

Korb, Cecilia 30 August 2013 (has links)
Made available in DSpace on 2015-04-14T13:33:08Z (GMT). No. of bitstreams: 1 451920.pdf: 503995 bytes, checksum: 18877f49594a02c1abdbc2ab1583ecfb (MD5) Previous issue date: 2013-08-30 / Objective : to evaluate the effects of positive fluid balance in infants under one year with bronchiolitis undergoing mechanical ventilation. Methodos : retrospective cohort study based on analysis of medical records of infants under one year admitted from April 2008 to September 2011 with bronchiolitis requiring mechanical ventilation in a tertiary Pediatric Intensive Care Unit (PICU) in southern of Brazil. We excluded patients with chronic lung disease, tracheostomy and previous use of mechanical ventilation due to acute pulmonary disease. We calculated the cumulative fluid balance within the first 3 days of the onset of mechanical ventilation. The outcomes assessed were ventilator-free days, length of stay in PICU, ventilator parameters used on the third day. Results : eighty-one patients were included in the study, 49 males (60.5%). The mean cumulative fluid balance on the third day of mechanical ventilation was 139 ? 68 ml/kg, the ventilator-free days was 19.7 ? 5.7 and the length of stay in PICU was 10.4 ? 5 6 days. In multivariate analysis, increasing cumulative fluid balance on the third day of mechanical ventilation was associated with a lower number of ventilatorfree days (&#946; -.03; 95% CI -.05, -.01; p <.001). The increasing cumulative fluid balance on the third day was also associated with higher PEEP and higher FiO2 used on the same day (&#946; .01; 95% CI.006, .019; p <.001 and &#946; .09; 95% CI .053, .136; p <.001 respectively). There was no relationship between cumulative fluid balance and length of stay in PICU (p = .950). Conclusion : cumulative fluid balance on the third day of mechanical ventilation is an independent risk factor for a lower number of ventilator-free days in infants under one year with bronchiolitis. There is also an association between higher cumulative fluid balance on the third day of mechanical ventilation and higher PEEP and higher FiO2 on the same day. / Objetivo : avaliar os efeitos do balan?o h?drico positivo em lactentes menores de um ano com bronquiolite viral aguda submetidos ? ventila??o mec?nica. Material e m?todo : estudo de coorte retrospectivo baseado na an?lise de prontu?rios de lactentes menores de um ano admitidos no per?odo de abril de 2008 a setembro de 2011 por bronquiolite viral aguda e submetidos ? ventila??o mec?nica em uma Unidade de Terapia Intensiva Pedi?trica (UTIP) terci?ria no sul do Brasil. Foram exclu?dos os pacientes com doen?a pulmonar cr?nica, traqueostomizados e com uso pr?vio de ventila??o mec?nica devido ? doen?a pulmonar aguda. Foi calculado o balan?o h?drico cumulativo nos primeiros 3 dias do in?cio da ventila??o mec?nica. Os desfechos avaliados foram: dias livres de ventila??o mec?nica, tempo de interna??o na UTIP e par?metros de ventila??o mec?nica utilizados no terceiro dia. Resultados : oitenta e um pacientes foram inclu?dos no estudo, sendo 49 meninos (60,5%). A m?dia do balan?o h?drico cumulativo no terceiro dia de ventila??o mec?nica foi de 139 ? 68 ml/kg, de dias livres de ventila??o mec?nica foi 19,7 ? 5,7 e do tempo de interna??o na UTIP foi 10,4 ? 5,6 dias. Na an?lise multivari?vel, um maior balan?o h?drico cumulativo no terceiro dia de ventila??o mec?nica apresentou associa??o com um menor n?mero de dias livres de ventila??o mec?nica (&#946; -0,03; IC 95% -0,05 a -0,01; p <0,001). O balan?o h?drico cumulativo no terceiro dia tamb?m apresentou associa??o com a utiliza??o de maior PEEP e FiO2 neste mesmo dia (&#946; 0,01; IC 95% 0,006 a 0,019; p <0,001 e &#946; 0,09; IC 95% 0,053 a 0,136; p <0,001 respectivamente). N?o houve rela??o entre balan?o h?drico cumulativo e tempo de interna??o na UTIP (p=0,950). Conclus?o : o balan?o h?drico cumulativo no terceiro dia de ventila??o mec?nica constitui fator de risco independente para um menor n?mero de dias livres de ventila??o mec?nica em lactentes menores do um ano com bronquiolite viral aguda. Existe, tamb?m, associa??o entre um maior balan?o h?drico cumulativo no terceiro dia de ventila??o mec?nica e a utiliza??o de maior PEEP e maior FiO2 neste mesmo dia.

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