Introdução. O transporte é um procedimento crítico na manutenção da cadeia do frio do sangue. Falhas neste procedimento podem comprometer a sua qualidade e a segurança transfusional. Objetivo. Avaliar as não conformidades (NC) do Hemocentro de Ribeirão Preto relacionadas ao transporte de concentrado de hemácias (CH). Analisar caixas térmicas e gelos recicláveis submetidos à temperatura de 20°C e 30°C e propor melhorias neste processo. Métodologia. Estudo retrospectivo de NC relacionadas ao transporte de CH no software do sistema da qualidade do Hemocentro de Ribeirão Preto e pesquisa experimental realizada com três caixas diferentes em combinação com três gelos recicláveis distintos, simulando uma situação de transporte, nas temperaturas externas de 20°C e 30°C. Realizou-se uma estatística descritiva com os dados. Utilizou-se a metodologia de análise de variância (ANOVA), com o auxílio do software SAS® 9, utilizando a PROC GLM. Para as comparações foram utilizados contrastes ortogonais baseados na distribuição t. Resultados. Os resultados mostraram diferenças significativas no desempenho entre as caixas e entre os gelos recicláveis. No entanto, as maiores diferenças ocorreram entre as temperaturas externas de 20°C e 30°C, indicando a interferência da temperatura externa na temperatura do conteúdo interno. Outra diferença encontrada foi entre pontos de aferição das temperaturas, dentro da mesma caixa, indicando que a distribuição do ar, no interior da caixa não é homogênea. Conclusão. São vários os interferentes existentes durante o transporte de CH, que podem comprometer a qualidade do sangue. O transporte deve ser validado, padronizando o maior número de variáveis possíveis, para minimizar as adversidades que ocorrem durante o procedimento / Introduction. The transport is a critical procedure in the maintenance of the blood cold chain. Failures in this procedure can compromise the blood quality and transfusion safety. Purpose: Evaluate the non-conformances (NC) of Hemocentro de Ribeirão Preto related to the Red Blood Cell (RBC) transport. Verify coolers, recycle ice at a temperature of 20°C and 30°C and propose improvements in this process. Methodology: Retrospective study of NC related to RBC transport in Hemocentro de Ribeirão Preto quality system software. Experimental research performed with three different insulated boxes combined with three different ice packs, simulating a situation of transport in the external temperatures of 20°C and 30°C. It was made a descriptive statistic of the data. The methodology of analysis of variance was used, through the software SAS® 9, using a PROC GLM. To do the comparisons orthogonal contrasts based on t distribution were used. Results: The results shown significant differences between insulated box and ice packs. However, the larger differences occurred between the temperatures of 20°C and 30°C, indicating that the external temperature interfere in the temperature inside the box. Another difference found was between points of temperature, inside the same insulated box, indicating that the air distribution inside the insulated box is not homogeneous. Conclusion. During RBC transport, many interfering exist that can compromise the blood quality. The transport must be validated, standardizing the largest number of details that is possible, to minimize adversity that occur during the procedure

Introdução. O transporte é um procedimento crítico na manutenção da cadeia do frio do sangue. Falhas neste procedimento podem comprometer a sua qualidade e a segurança transfusional. Objetivo. Avaliar as não conformidades (NC) do Hemocentro de Ribeirão Preto relacionadas ao transporte de concentrado de hemácias (CH). Analisar caixas térmicas e gelos recicláveis submetidos à temperatura de 20°C e 30°C e propor melhorias neste processo. Métodologia. Estudo retrospectivo de NC relacionadas ao transporte de CH no software do sistema da qualidade do Hemocentro de Ribeirão Preto e pesquisa experimental realizada com três caixas diferentes em combinação com três gelos recicláveis distintos, simulando uma situação de transporte, nas temperaturas externas de 20°C e 30°C. Realizou-se uma estatística descritiva com os dados. Utilizou-se a metodologia de análise de variância (ANOVA), com o auxílio do software SAS® 9, utilizando a PROC GLM. Para as comparações foram utilizados contrastes ortogonais baseados na distribuição t. Resultados. Os resultados mostraram diferenças significativas no desempenho entre as caixas e entre os gelos recicláveis. No entanto, as maiores diferenças ocorreram entre as temperaturas externas de 20°C e 30°C, indicando a interferência da temperatura externa na temperatura do conteúdo interno. Outra diferença encontrada foi entre pontos de aferição das temperaturas, dentro da mesma caixa, indicando que a distribuição do ar, no interior da caixa não é homogênea. Conclusão. São vários os interferentes existentes durante o transporte de CH, que podem comprometer a qualidade do sangue. O transporte deve ser validado, padronizando o maior número de variáveis possíveis, para minimizar as adversidades que ocorrem durante o procedimento / Introduction. The transport is a critical procedure in the maintenance of the blood cold chain. Failures in this procedure can compromise the blood quality and transfusion safety. Purpose: Evaluate the non-conformances (NC) of Hemocentro de Ribeirão Preto related to the Red Blood Cell (RBC) transport. Verify coolers, recycle ice at a temperature of 20°C and 30°C and propose improvements in this process. Methodology: Retrospective study of NC related to RBC transport in Hemocentro de Ribeirão Preto quality system software. Experimental research performed with three different insulated boxes combined with three different ice packs, simulating a situation of transport in the external temperatures of 20°C and 30°C. It was made a descriptive statistic of the data. The methodology of analysis of variance was used, through the software SAS® 9, using a PROC GLM. To do the comparisons orthogonal contrasts based on t distribution were used. Results: The results shown significant differences between insulated box and ice packs. However, the larger differences occurred between the temperatures of 20°C and 30°C, indicating that the external temperature interfere in the temperature inside the box. Another difference found was between points of temperature, inside the same insulated box, indicating that the air distribution inside the insulated box is not homogeneous. Conclusion. During RBC transport, many interfering exist that can compromise the blood quality. The transport must be validated, standardizing the largest number of details that is possible, to minimize adversity that occur during the procedure

With the explosion in usage of big data, stakes are high for companies to develop workflows that translate the data into business value. Those data transformations are continuously updated and refined in order to meet the evolving business needs, and it is imperative to ensure that a new version of a workflow still produces the correct output. This study focuses on the validation of big data in a real-world scenario, and implements a validation tool that compares two databases that hold the results produced by different versions of a workflow in order to detect and prevent potential unwanted alterations, with row-based and column-based statistics being used to validate the two versions. The tool was shown to provide accurate results in test scenarios, providing leverage to companies that need to validate the outputs of the workflows. In addition, by automating this process, the risk of human error is eliminated, and it has the added benefit of improved speed compared to the more labour-intensive manual alternative. All this allows for a more agile way of performing updates on the data transformation workflows by improving on the turnaround time of the validation process.

One of the early steps in axial turbine design is the use of one-dimensional (1D) mean line calculations to predict the turbine performance and estimate the principal geometric parameters, such as radius and blade heights, that will be needed in further computational fluid dynamic (CFD) studies. This 1D analysis is based on the estimation of the aerodynamic losses expressed as a function of simple blade parameters and the velocity triangles. In this regard, there exist different loss correlations widely used in literature to estimate these losses but at the same time there is a lack of information regarding differentiation between them. Thereafter, the objective in this work was to judge and compare the behaviors of the Kacker- Okapuu, Craig-Cox and Denton loss correlations, all of them widely-used in turbine performance prediction. Present work shows the implementation of these different loss correlations on an existing 1D mean line numerical tool, LUAX-T. Subsequently, once implemented, the correlations were compared and analyzed by the use of a validation process and performing a parametric study. The results show that similar key parameters such as the flow turning, solidity and aspect ratio rule the different loss mechanisms in each correlation. On the other hand, the parametric study shows that the correlations are in agreement with the theory and give similar trends for performance prediction even though they all predict different values of efficiency for the same turbine stage. Moreover, the validation process show the correlations were found to be accurate enough when comparing against two different sets of experimental data. However, it was also proved that the models are only accurate if used within the range of applicability they were developed for, hence a complete knowledge of the limitations of each correlation should be known prior to using them. Finally, the extension of the one-dimensional mean line numerical tool LUAX-T will serve to perform further studies related to turbine design, as there are very few non-confidential turbomachinery design tools available for teaching or researching. Furthermore, a parametric study tool was also developed as part of the program. This last extension and the loss implementation codes are described in this work.