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The system of higher education in the United States of America has retained some of its original character yet it has also grown in many ways. Among the contemporary priorities of colleges and universities are undergraduate student learning outcomes and success along with a growing focus on diversity. As a result, there has been a growing focus on ways to achieve compositional diversity and a greater sense of inclusion with meaningful advances through better access and resources for individuals from non-dominant populations. The clearest result of these advances for sexual and gender diversity has been a normalization of lesbian, gay, bisexual, transgender, and queer (LGBTQ) identities through positive visibility and greater acceptance on campus. However, it appears that relatively few institutions have focused on improving academic diversity and students’ cognitive growth around LGBTQ issues. Through historical inquiry and a qualitative approach, this study explored the fundamental aspects of formal LGBTQ studies academic programs at some of the leading American research universities, including Cornell University, the University of Maryland, College Park, and the University of Texas at Austin – a purposeful sample chosen from the Association of American Universities (AAU) member institutions with organized curricula focused on the study of sexual and gender diversity. The analysis of primary and secondary sources, including documents and interviews, helped create historical narratives that revealed: a cultural shift was necessary to launch a formal academic program in LGBTQ studies; this formalization of LGBTQ studies programs has been part of the larger effort to improve the campus climate for sexual and gender diversity; and there has been a common pattern to the administration and operation of LGBTQ studies. Clearly, the research shows that LGBTQ studies, as a field of study and formal curriculum, has become institutionalized at the American research university. A key outcome of this research is the creation of a historiography of curricular development around sexual and gender diversity at a sample of premier research universities. This work also begins to fill the gap in the study of academic affairs at the postsecondary level of education related to LGBT and queer studies and the organization and administration of learning about diversity and inclusion. Ultimately, the results of this study can influence the continued advancement and maturity of this legitimate field of study as well as academic diversity and social transformation around sexual and gender diversity.