Background: The tradition of specialised institutional alcohol treatment in what is now the Czech Republic dates back over a hundred years. The first modern institution aimed at treating alcohol dependency began to operate on 7 September 1948. While formally constituting an organisational unit of the Psychiatric Clinic, the "U Apolináře" facility, headed by Dr. Jaroslav Skála, was an independent workplace which gave rise to a distinct treatment approach. Becoming known as the "Apolinar" treatment model, this approach was adopted by all the residential alcohol treatment facilities which came into existence or operated in Czechoslovakia from 1948 to 1989. Before the establishment of this department, three similar treatment facilities existed on the historical territory of Czechoslovakia - Velké Kunčice (1911 to 1915), Tuchlov (1923 to 1938), and Istebné nad Oravou (1937 to 1939/1949). Aim: The aim of the dissertation thesis was to describe the analysis of the conditions which had an influence on the origin, development, operation, and dissolution of the three oldest specialised alcohol treatment institutions on the historical territory of what is now the Czech Republic and Slovakia from 1900 to 1945. Methods: The research involved qualitative content analysis of historical materials, mainly written...

Background: The tradition of specialised institutional alcohol treatment in what is now the Czech Republic dates back over a hundred years. The first modern institution aimed at treating alcohol dependency began to operate on 7 September 1948. While formally constituting an organisational unit of the Psychiatric Clinic, the "U Apolináře" facility, headed by Dr. Jaroslav Skála, was an independent workplace which gave rise to a distinct treatment approach. Becoming known as the "Apolinar" treatment model, this approach was adopted by all the residential alcohol treatment facilities which came into existence or operated in Czechoslovakia from 1948 to 1989. Before the establishment of this department, three similar treatment facilities existed on the historical territory of Czechoslovakia - Velké Kunčice (1911 to 1915), Tuchlov (1923 to 1938), and Istebné nad Oravou (1937 to 1939/1949). Aim: The aim of the dissertation thesis was to describe the analysis of the conditions which had an influence on the origin, development, operation, and dissolution of the three oldest specialised alcohol treatment institutions on the historical territory of what is now the Czech Republic and Slovakia from 1900 to 1945. Methods: The research involved qualitative content analysis of historical materials, mainly written...

Familial risk and environmental stress promote the development of alcohol dependence. We investigated whether a positive family history of alcoholism affects the neuroendocrine response to a standardized laboratory stress test in healthy subjects without alcohol use disorders. Twenty-four high-risk subjects with a paternal history of alcoholism (PHA) and 16 family history negative (FHN) controls were evaluated. Psychosocial stress was induced by having subjects deliver a 5-min speech and mental arithmetics in front of an audience on separate days, after drinking either placebo or ethanol (0.6 g/kg) in a randomized sequence. Adrenocorticotropin (ACTH) was measured in 10 plasma samples covering up to 75 min after the stress test. Plasma arginine vasopressin (AVP) was determined before the stressor, at the time of maximum ACTH secretion, and at 75 min after stress onset. The stress test induced a phasic increase in ACTH secretion. At the time of maximum ACTH, AVP was significantly increased in relation to baseline. Compared to placebo, alcohol administration significantly attenuated maximum ACTH concentration in PHA but not FHN subjects, and decreased AVP measured in the same samples in PHA but not FHN subjects. We conclude that activation of the hypothalamic–pituitary–adrenal system by psychosocial stress is accompanied by an increase in peripheral plasma AVP levels. Secretion of both ACTH and AVP suggest that alcohol attenuates the stress response selectively in PHA but not FHN subjects. This might imply some short-term positive alcohol effect in sons of alcoholics, but also constitute a mechanism by which their risk to develop alcohol use disorders is increased.

Hintergrund. In klinischen und epidemiologischen Untersuchungen wurden retrospektiv Assoziationen zwischen Angst- und Alkoholstörungen bestätigt. Bei Personen, die von beiden Störungen betroffen waren, fand man restrospektiv meist einen früheren Beginn der Angststörungen im Vergleich zu den Alkoholstörungen, was kausal im Sinne der Selbstmedikationshypothese interpretiert wurde. Diese konnte bisher nicht eindeutig bestätigt werden. Zur Aufklärung notwendige prospektive Untersuchungen, die Angststörungen auf diagnostischer Ebene erfassen, zwischen verschiedenen Angststörungen unterscheiden und sich auf Jugendliche beziehen, fehlen bisher. Fragestellung. Die Bedeutung von Angststörungen für die Entwicklung von erhöhtem Alkoholkonsum und Alkoholstörungen bei Jugendlichen und jungen Erwachsenen. Methodik. Die Analysen basieren auf den Daten der prospektiv-longitudinalen EDSP-Studie (Follow-Up: insg. 4 Jahre) mit einer epidemiologischen, repräsentativen Stichprobe von 3021 Personen im Alter zwischen 14 und 24 Jahre zu T0 aus München und Umland. Zur Erhebung von DSM-IV-Diagnosen wurde das M-CIDI verwendet. Ergebnisse. Primäre Panikstörungen, Panikattacken und Soziale Phobie erwiesen sich prospektiv als spezifische Prädiktoren für Beginn und Aufrechterhaltung von Alkoholproblemen. Umgekehrt waren Alkoholprobleme mit einem erhöhten Risiko für den Beginn von Sozialer Phobie und GAS assoziiert. Bezüglich DSM-IV Diagnosekriterien fanden sich phobische Ängste sowie Episoden intensiver Angst als Risikofaktoren für den Beginn von Alkoholproblemen. Vermeidungsverhalten war mit einem verminderten Risiko für nachfolgende Alkoholprobleme verbunden. Schlussfolgerungen. Maßnahmen zur Prävention von Alkoholproblemen können sich zielgruppenorientiert an Jugendliche mit Sozialer Phobie und Paniksymptomatik richten. Bei Patienten, die sich wegen Alkoholproblemen in Behandlung begeben, ist eine umfassende Diagnostik zur Identifikation zusätzlicher Angststörungen ratsam. / Background. Many clinical and epidemiological studies have documented significant cross-sectional comorbidities between anxiety disorders and alcohol use disorders. Analysis of retrospective age-of-onset reports suggests that the anxiety disorders often start earlier than the alcohol disorders. These data have often been interpreted in terms of a self-medication-model implying a causal mechanism. Overall, in former studies this model couldn't definitely be proofed. Prospective studies that follow a sample of adolescents into adulthood assessing different anxiety disorders on an diagnostic level are needed to confirm these associations. Methods. Baseline and four-year-follow-up data from the EDSP-Study, a prospective community survey of 3021 (2548 at follow-up) adolescents and young adults aged 14 to 24 years at baseline carried out in Munich, were used. DSM-IV anxiety disorders, alcohol use and alcohol use disorders were assessed with the M-CIDI. Results. While in retrospective analyses strong associations between nearly all anxiety disorders and alcohol problems, especially harmful use and dependence, were found, prospective analyses showed that only primary panic disorder, panic attack and social phobia are specific predictors of subsequent onset and persistence of alcohol problems. Contrary, primary alcohol problems were related to subsequent onset of social phobia and GAD. Considering the different DSM-IV-criteria, phobic anxiety as well as episodes of intensive anxiety were found to be risk factors for the following onset of alcohol problems. Avoidance behavior was associated with a lower risk for subsequent alcohol problems. Conclusions. Alcohol prevention programs could be directed to target groups with social phobia and panic. Patients with alcohol problems should carefully be screened for comorbid anxiety disorders. In order to prevent relapses the treating of social phobia and panic should be part of the therapy with comorbid alcohol patients.

This diploma work named Socio-Pathological Phenomena at Secondary Vocational School and Their Possible Solution deals, in its theoretical part, with the basic terminology related with this topic. It also focuses on the risk behaviour among today's young people, and briefly introduces socio-pathological phenomena which occured at the surveyed secondary school in the last two years. It also describes other kinds of contemporary risk behaviour among young generation. At the end of theoretical part, there are introduced some of the current trends in school prevention and solution of socio-pathological phenomena. Period of adolescence is of course closely associated with this topic. It's called critical stage, and all the students pass this period during their secondary school attendance. That's why the chapter devoted to adolescence is elaborated in full details. Gender differences concerning appearance and intensity of socio-pathological phenomena are also mentioned here. Next, there is explained the system of primary prevention in The Czech Republic, the importace of family and school background, the impact of peers on personality development. In empirical part of this diploma work, there is introduced Secondary Vocational School, Ltd., 844 Schulhoffova, in Prague 4. The research probe was realized...

This diploma thesis explores the phenomenon of formation and development of alcohol dependence. In the first series focuses on the historical description, which demonstrates considerable anchored in the life of our ancestors already. It also defines the concept of addiction, its causes and consequences, whether psychological, medical or social. Its objective is to describe the possibilities of social work in this phenomenon. defines therefore primarily targets and understanding of social work and consequently specifics of client alcoholism. An important element is the role of the social worker in the client's motivation to change, which uses Nešpor's model of spontaneous changes in motivation. Then, on the basis of available social services selects several most suitable, which can help to improve the client's situation. Has an essential role in this issue also primary prevention, ie it discusses the methodology, target groups, focusing on adolescents and the focus is on the firm role of the family. Finally contains some official documents on primary prevention, which are discussed current issues of primary prevention practice and subsequent survey, mapping aspect of social workers on the incidence risk of alcohol dependence among adolescents attending social facilities.