In 2009, approximately 1.7 million people died of tuberculosis. The emergence of drug-resistant strains of Mycobacterium tuberculosis (M. tuberculosis) has created an urgent demand for the development of new anti-tuberculosis (anti-TB) drugs and treatments. M. tuberculosis, the causative agent, has a protective complex cell wall structure that is essential for its survival. One of the major building blocks of the cell wall structure is an arabinofuranosyl polysaccharide called arabinan. Since arabinan is not present in mammals, it has become a promising target for anti-TB drug development. The arabinan component is biosynthesized by a family of arabinofuranosyltransferases (araTs) using the substrate decaprenolphosphoarabinose (DPA) as the donor of arabinose. This project targets the biosynthesis of arabinan by synthesizing analogues of DPA as potential inhibitors of araTs. A sulfamide moiety was chosen as an isosteric replacement of the phosphate group of DPA. To mimic the polyprenyl chain of DPA, a series of alkyl chains of varying length and a triethylene glycol (TEG) derived chain were used.

全文計七章：共二十三節，約十萬餘字。 　　第一章　緒論，就本論文的研究動機與目的、研究問題與資料，研究途徑與方法等加以說明。 　　第二章　敘述海協會的成立的仍是國際環境，兩岸政治背景互動下的產物，本章就是依上述方向加以探討。 　　第三章　詳細說明海協會成立的意圖，基本職能、組織結構，並對主要成員言論加以分析。 　　第四章　針對海協會在中共當前對台政策及組織中的角色與功能深入分析。 　　第五章　研究海協會在目前兩岸互動中的運作功能，分就兩岸仲介團體加以比較，海協會實際運作功能探討，以及兩會運作後所面對的問題進行分析與說明。 　　第六章　簡析本論文對兩會會談成果、影響因素、以及對兩會未來運作之期望。 　　第七章　結論，就海協會的綜合性目的、功能、以及對未來可能的發展進行評估與說明。