Magister Artium - MA / The black middle class of South Africa has been the subject of academic and media fascination since the democratisation of South Africa almost 30 years ago. However, this attention tends to portray a one-dimensional and homogenous image of the black middle class. The homogenising of this group often involves derogatory stereotypes and framing the group as shallow, and prone to especially excessive conspicuous consumption and vulgar displays of wealth and material possessions. Implicitly or overtly, the black middle class is therefore not seen as a bona fide middle class, i.e. entrepreneurial, zealous, dynamic and enterprising in demanding social recognition. Through the lens of food and food culture (which uses Pierre Bourdieu’s theory of class and capital distinction), this thesis undertakes a phenomenological exploration of a group that is not only heterogeneous but also very energetically rebuilding a sense of self and dignity in the face of power relations, racism and stereotypes linked to colonialism, apartheid and post-colonial politics. The findings of this thesis reveal that black middle-class South Africans are determined to (a) affirm their belonging in society, (b) confirm their class standing and access to capital, and, (c) establish their individual identities as well as an individualised group identity. In the face of continuing inequality, unequal power relations and tense social relations, this group has developed strategies to mitigate and navigate these challenges. This thesis identified two key strategies that are employed by black consumers both online and in the field: ‘eating without food’ and the ‘cultured palate’ (my terms). These two strategies empower practitioners to navigate foodscapes and social spaces as well as demonstrate their class belonging.

Accurate diagnosis of small‐cell carcinoma of the lung (SCLC) is clinically important because of the therapeutic implications. SCLC must be distinguished from non‐small‐cell carcinoma (NSCLC) and lymphoma. Paranuclear blue inclusions (PBIs) were recently described as a feature of metastatic SCLC on air‐dried Wright‐stained bone marrow aspirate smears. To determine the utility of PBIs in distinguishing SCLC from NSCLC and lymphoma, we evaluated air‐dried Diff‐Quik‐stained smears from 103 fine‐needle aspiration (FNA) specimens and 14 touch imprint specimens. PBIs were identified in 24 (89%) of 27 cases of SCLC, in 6 (9%) of 64 non‐small‐cell carcinomas (P < 0.00001), and in two (8%) of the 26 lymphoma cases (P < 0.00001). No PBIs were seen on any of the alcohol‐fixed Papanicolaou or hematoxylin‐eosin (HandE) stained smears examined. In conclusion, PBIs appear to be a feature of SCLC on air‐dried cytologic material stained with Romanowsky type stains. In the presence of cytologic features of SCLC, the identification of PBIs provides a useful diagnostic feature for diferentiating between SCLC and NSCLC carcinomas, and between SCLC and lymphomas in FNA specimens and touch imprints from surgical specimens.

Cat scratch disease (CSD) is a self limited zoonotic disease that presents most commonly as a regional lymphadenopathy. We are reporting a case of a 25-year-old male patient who presented with fever and large right inguinal lymphadenopathy. The diagnosis of cat scratch disease was confirmed based on the characteristic cytopathological features on aspirate smears from the lymph node and the serological titers for Bartonella henselae. This case report emphasizes the importance of combining Bartonella serology, and cytopathology in the diagnostic work-up of febrile lymphadenopathy and suspected CSD since the culture of this organism is arduous.

Background: Anaplastic thyroid carcinoma (ATC) is a highly aggressive, undifferentiated carcinoma that may arise on top of normal or abnormal thyroid. Making the diagnosis by fine needle aspiration (FNA) of the thyroid with a long-standing history of multinodular goiter (MNG) is not uncommon. We report a case discussing the cytopathologic findings and the relationship with long-standing goiter and thyroid exposure to radioactive iodine treatment. Case: A 90-year-old male patient presented with a > 45-year history of MNG that was associated with thyrotoxicosis and multiple courses of radioiodine (I-131) treatment. He developed recent symptoms of dyspnea, dysphagia, neck swelling and unintentional weight loss. Computed tomography of the neck was done revealing a large MNG with retrosternal extension and calcifications. FNA was performed revealing highly anaplastic cells with a colloid background and presence of neutrophils. The diagnosis of ATC was made. The patient refused any kind of management and was discharged upon his request. He died 2 days after the procedure, and no autopsy was performed. Conclusion: ATC is an aggressive, undifferentiated thyroid carcinoma that can be diagnosed by FNA and save the patient a surgical intervention. A background of MNG and history of radioactive iodine therapy is not uncommon.

BACKGROUND. The cytologic differentiation between neoplastic and reactive/reparative processes in the endoscopic ultrasound-guided fine-needle aspirations (EUS-FNA) of the pancreas can be difficult. Malignant transformation of the pancreatic ductal epithelium changes the expression of apomucins. The goal of the current study was to determine an optimal immunohistochemical panel of mucin (MUC) antibodies that would allow the cytomorphologic distinction of pancreatic ductal adenocarcinoma and its differentiation from reactive/reparative processes and inadvertently sampled gastric and duodenal mucosa. METHODS. Pancreatic EUS-FNA specimens performed on 351 patients were reviewed. Expression profiles of MUC1, 2, 5AC, and 6 were examined on 56 cell block sections and 26 follow-up pancreatectomy specimens. RESULTS. MUC1 and 6 expression was found in nonneoplastic pancreatic samples, whereas there was an absence of expression of MUC2 and 5AC. MUC2 was detected in mucosal goblets cells of the duodenum, MUC6 in Brunner glands, and MUC5AC in gastric foveolar cells. MUC5AC expression in differentiating ductal adenocarcinomas from benign conditions demonstrated better operating characteristics than either MUC1 or MUC6. The apomucin expression pattern both in cytology and follow-up surgical pathology specimens was similar. In surgical pathology specimens, the panel of 3 antibodies, MUC1+/MUC2-/MUC5AC+, was noted in 15 of 17 ductal carcinomas (88.2%). In nonneoplastic pancreatic tissue, the expression panel MUC1+/MUC2-/MUC5AC- was observed in 14 of 17 (82.4%) cases. In cytology specimens, the combination of MUC1+/MUC2-/MUC5AC+ was noted in 21 of 30 ductal carcinoma cases (70.0%), 3 of 6 atypical cases (50%), and 1 of 1 suspicious for malignancy cases (100%). The combination MUC1+/MUC2-/MUC5AC+ was not observed in any of the negative for malignancy or reactive cases (0 of 6). CONCLUSIONS. The most optimal panel for the diagnosis of ductal adenocarcinoma in both the EUS-FNA specimens is a panel including MUC1/MUC2/MUC5AC, whereas a panel of all 4 antibodies (MUC1, 2, 5AC, and 6) will in addition aid in differentiating inadvertently sampled normal/reactive duodenal and gastric epithelium from neoplastic pancreatic tissue.

Reforms early in the 21st century purported to close the achievement gap between White students and students of color, to provide accountability and transparency to taxpayers, to implement meaningful consequences for low-performing schools, and to create the workforce for the century. In this study, I investigated the effects of school reform on the lived experiences of students who graduated from high school in 2014 by inquiring into six young people’s perceptions of their schooling. I sought to better understand whether participants were aware of the existence and intent of school reforms, and how or whether their aspirations for their futures had evolved over the course of their formal schooling in concert with the expressed goals of those reforms. The data set consisted of narratives from six recent low-income male and female high school graduates of color. Analysis revealed striking similarities between their experiences despite the variety in outcomes. The narratives indicated that school reforms have had little impact on students’ lives other than to graft the go-to-college imperative, onto the young people’s inherent aspirations. Young people remained alienated from their education, and outcomes continued to adhere to racist, classist, and gendered expectations.

京都大学 / 0048 / 新制・論文博士 / 博士(医学) / 乙第13220号 / 論医博第2167号 / 新制||医||1033(附属図書館) / (主査)教授 高橋 淳, 教授 宮本 享, 教授 伊佐 正 / 学位規則第4条第2項該当 / Doctor of Medical Science / Kyoto University / DFAM

Thesis (Ph.D.)--University of the Witwatersrand, Faculty of Commerce, Law & Management, School of Economic and Business Sciences, 2014. / South Africa’s Total Entrepreneurial Activity (TEA) scores are consistently well-below the average of other efficiency-driven economies, as well as for other sub-Saharan countries (Turton and Herrington, 2013). Despite this, a 2013 Global Entrepreneurship Monitor (GEM) report suggests that youth in sub-Saharan Africa demonstrate marked entrepreneurial propensity and potential (Kew, Herrington, Letovsky and Gale, 2013). As such, this thesis seeks to contribute an understanding of how black, youth entrepreneurs located in Johannesburg’s informal economy, seek to achieve legitimacy, and thus ‘become’, through the attainment of an accepted entrepreneurial identity. To this end, the role of hybridity, as a form of entrepreneurial capital, is explored as a potential mechanism. A hypothesised conceptual framework is accordingly evolved which explores the relationships between entrepreneurial identity aspiration, resource attainment, legitimacy, and how these are mediated by hybridity. Survey data gathered from young, black entrepreneurs (n=503) across Johannesburg’s seven administrative districts, using a structured questionnaire, and tested using multiple regression analysis, reveals the following: a direct relationship between entrepreneurial identity aspiration, entrepreneurial resources as well as the attainment of legitimacy is found, suggesting that black youth do indeed aspire to entrepreneurial legitimacy, and thus, seek to ‘become’ accordingly. Moreover, hybrid values are seen to mediate the relationship between entrepreneurial iii identity aspiration and resource attainment such that they accounted for the relationship. This suggests the potential for hybridity as a form of entrepreneurial capital such that values might have been seen to act as a form a catalyst for the attainment of other resources. The study contributes a conceptual framework which provides a theoretical understanding of young, black entrepreneurs in South Africa. More specifically, it suggests a values-mediated relationship between entrepreneurial identity aspiration and the attainment of resources such that youth seek legitimacy accordingly. As such, this study is the first to provide insights into the potential impact that hybrid values might have on shaping an entrepreneurial identity. Additionally, it contributes evidence to suggest that opportunity-driven behaviour motivates young, black entrepreneurs in Johannesburg’s informal economy, beyond necessity motives which are used to stereotypically frame this space. It is recommended that further research be undertaken to test this framework in other contexts in order to gain a finer understanding of hybridity as a potential entrepreneurial resource. This might additionally involve research into the cues that potentially result in a switching between different values.

京都大学 / 新制・課程博士 / 博士(地域研究) / 甲第24722号 / 地博第314号 / 新制||地||121(附属図書館) / 京都大学大学院アジア・アフリカ地域研究研究科東南アジア地域研究専攻 / (主査)教授 片岡 樹, 教授 玉田 芳史, 教授 速水 洋子, 准教授 LOPEZ Mario Ivan / 学位規則第4条第1項該当 / Doctor of Area Studies / Kyoto University / DGAM

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