Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-01-12T15:47:40Z No. of bitstreams: 1 AlaineMariaDosSantosSilva_DISSERT.pdf: 1484646 bytes, checksum: 62cb7f8d64bbe20a976f9f93244e0898 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-01-20T13:39:52Z (GMT) No. of bitstreams: 1 AlaineMariaDosSantosSilva_DISSERT.pdf: 1484646 bytes, checksum: 62cb7f8d64bbe20a976f9f93244e0898 (MD5) / Made available in DSpace on 2017-01-20T13:39:52Z (GMT). No. of bitstreams: 1 AlaineMariaDosSantosSilva_DISSERT.pdf: 1484646 bytes, checksum: 62cb7f8d64bbe20a976f9f93244e0898 (MD5) Previous issue date: 2015-07-02 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) / O Benznidazol (BZN) ? o agente quimioterap?utico mais frequentemente utilizados para o tratamento de pacientes com doen?a de Chagas. Apesar de seu uso difundido, revela alta toxicidade, baixa efic?cia, al?m da dificuldade de atravessar as barreiras biol?gicas. O objetivo deste trabalho foi produzir nanopart?culas biodegrad?veis funcionalizados com ?cido si?lico e colesterol potencialmente capazes de direcionar o f?rmaco para c?lulas infectadas pelo parasita Trypanosoma cruzi. Uma optimiza??o sistem?tica foi realizada usando o m?todo de evapora??o com emulsifica??o do solvente. O efeito das vari?veis ao obter essas nanopart?culas foram avaliados pela medi??o do tamanho m?dio de part?cula, ?ndice de polidispersidade, medi??es de potencial zeta, microscopia de for?a at?mica (AFM), infravermelho transformada de Fourier (FTIR-ATR) e efici?ncia de encapsula??o. Entre as vari?veis inclui a velocidade de agita??o, concentra??o de pol?mero, agente tensioativo, tipo de inje??o da amostra (seringa, bureta, bomba perist?ltica) e do tipo de solvente org?nico utilizado (DCM, DCM:EtOH, DCM:ACE) em diferentes propor??es. As nanopart?culas apresentaram forma esf?rica e valores de potencial zeta positivos por volta de +25mV. O DCM / EtOH (50:50 v/v) foi estabelecido para produzir as part?culas menores e com boa efici?ncia de carga da droga, tanto para nanopart?culas contendo apenas o BNZ, quanto para as nanopart?culas com superf?cie modificada. Os resultados sugerem a utiliza??o de c?lulas de Franz como um m?todo eficiente para avaliar o potencial in vitro das nanopart?culas. Todos sistemas apresentaram vi?veis nas menores concentra??es utilizadas e apresentaram estabilidade durante seis semanas. As vari?veis estudadas foram otimizadas com sucesso para selecionar os par?metros adequados para a formula??o de nanopart?culas para a incorpora??o de BNZ.

The thesis analyses the differences that result from using of specific data collection method, computer assisted telephone interviewing (CATI) and computer assisted personal interviewing (CAPI). The main findings are based on election model built by research agency TNS Aisa for elections to the Chamber of Deputies of the Parliament of the Czech Republic in 2013. The aim of the thesis is to determine whether the chosen method of data collection influences the results of the estimated electoral preferences, to determine in which sociodemographic categories it is happening and whether the differences in the obtained data are related to the ideological orientation of the political parties. The dependence of the results on the data collection method is assessed by the chi-quadrate independence test. Further, through personal interviews with researchers, it is determined at what stage of the research process the data may be distorted and what its possible causes are. The benefit of the thesis is the finding that the chosen method of collection influences the established preferences among voters aged 30-44, university graduates and voters living in Prague. In these groups, the left-hand side ČSSD is preferred more by personal interviewing and right-handed TOP 09 through telephone interviewing. The collection of data itself was evaluated by the most risky phase of the research process, in which possible distortion could occur. While the accuracy of personal interviewing depends largely on the interviewer's personality, the sources of distortion of the telephone inquiry result more from the nature of the use of the phone itself.

Private business subjects are characterised by their continuous effort for increasing their market position. Therefore they are permanently monitoring their own sthrengths and weaknesses, and they are also monitoring their competitors´ behaviour and customers´ needs and wishes. Such pieces of information can be received by analysis of business surroundings and from custommers´ opinion. Activities like these are called marketing research. The research should include all aspects that influence the way of perception of the company by any other market subject, or even the atmosphere inside the company. Information received is valuable for managers and their decision-making. Marketing research is a dynamicly developing field where new findings of social sciences are permanently applied. A significant developement in this field was reached mainly in last years. It is a result of the rapid progress of information and communication technologies. Modern forms of marketing research often use the Internet for collecting various information on the market.

This research explores what type of verbal/text survey content translates effectively between survey modes within a Computer Assisted Telephone Interview (CATI) and Computer Assisted Web Interview (CAWI) mixed-mode survey project within unified mixed-mode survey design. This phenomenon is researched through the implementation of online probes within an existing CAWI survey project for sections close to an original CATI design. This research provides insights into how respondents understand and conceptualize verbal content within a unified mixed-mode CAWI survey in today’s online survey environment. This research is timely as the penetration of mobile has increased drastically, which may have implications on CAWI/CATI mixed-mode research considering the conflicting best practices for mobile CAWI survey design and CATI survey design. The results show that respondents do not engage with introductory pages enough to reliably recall their information, even when significantly shortened and simplified. Additionally, respondents are sensitive to high amounts of text and topics within survey question spaces. This means that some aspects of CATI survey design do not translate to CAWI and may even be cause for data quality concerns. These findings highlight some key issues faced by researchers and practitioners, provide some guidance on how design choices may impact results, and presents rich opportunities for future research.

This study focuses on the extent to which the various elements of corporate brand identity as identified in the literature are perceived to contribute to corporate brand image formation. In doing so, a theoretical perspective is adopted for this study that borrows from both marketing communication and corporate communication theories. Three data collection techniques – Q methodology, an online questionnaire and computer-assisted telephone interviews (CATI) – were used to determine to what extent these elements are perceived significant in corporate brand image formation among participants from 106 South African organisations across various business sectors. Four categories were identified to be perceived as significant for corporate brand image formation, namely transformational leadership and management, positioning and differentiation strategy, brand equity and employee orientation and mentorship. To date, a comprehensive measuring instrument that theoretically includes all the corporate brand identity elements perceived to be significant in corporate brand image formation has not been developed. Based on the research findings, the study aims to propose a theoretical framework for establishing a measuring instrument that includes all the corporate brand identity elements deemed significant in corporate brand image formation as perceived by South African organisations. The objective of providing a theoretical framework for establishing a measuring instrument is to enable organisations to assess the role of their corporate brand identity in corporate brand image formation among their stakeholder groups. The theoretical framework includes the four identified categories perceived as significant in corporate brand image formation. It indicates which of the corporate brand identity elements included in the four categories are perceived to be more significant in corporate brand image formation by South African organisations. In addition, it provides assumptions on how these corporate brand identity elements are perceived to work in synergy to enhance corporate brand image formation based on the research results. / Communication Science / D. Litt. et Phil. (Communication)

This study focuses on the extent to which the various elements of corporate brand identity as identified in the literature are perceived to contribute to corporate brand image formation. In doing so, a theoretical perspective is adopted for this study that borrows from both marketing communication and corporate communication theories. Three data collection techniques – Q methodology, an online questionnaire and computer-assisted telephone interviews (CATI) – were used to determine to what extent these elements are perceived significant in corporate brand image formation among participants from 106 South African organisations across various business sectors. Four categories were identified to be perceived as significant for corporate brand image formation, namely transformational leadership and management, positioning and differentiation strategy, brand equity and employee orientation and mentorship. To date, a comprehensive measuring instrument that theoretically includes all the corporate brand identity elements perceived to be significant in corporate brand image formation has not been developed. Based on the research findings, the study aims to propose a theoretical framework for establishing a measuring instrument that includes all the corporate brand identity elements deemed significant in corporate brand image formation as perceived by South African organisations. The objective of providing a theoretical framework for establishing a measuring instrument is to enable organisations to assess the role of their corporate brand identity in corporate brand image formation among their stakeholder groups. The theoretical framework includes the four identified categories perceived as significant in corporate brand image formation. It indicates which of the corporate brand identity elements included in the four categories are perceived to be more significant in corporate brand image formation by South African organisations. In addition, it provides assumptions on how these corporate brand identity elements are perceived to work in synergy to enhance corporate brand image formation based on the research results. / Communication Science / D. Litt. et Phil. (Communication)