Medication-related injuries are one of the major problems with today’s healthcare. Some commonmedication errors are inaccurate prescriptions by physicians, medication given to the wrongpatient or miscalculated doses. An important part of the medication administration are nurses,who spend about a quarter of their time administrating medication. Since they oversee the lastcontrol, checking that the correct medication is being administrated, they can prevent manymedication errors from occurring. Their working conditions are far from optimal, characterized bystaff shortages and overcapacity which result in a stressful work environment. This study aims to create a requirement specification of a future system for medicationadministration. The system will be used for inpatient care and by using a solution called closedloop medication, the system aims to reduce the medication errors as well as reduce the nurses’workload. Closed loop medication uses electronic verification to eliminate the errors that occurbetween prescription and administration by ascertain the five rights of medication (five R). Theseare principles that ensure that the right drug, with the right dose and right the route, is given tothe right patient, at the right time. The methods used for the investigation were observations as well as seminars. The observationsdemonstrated how the medication administration is carried out today while the seminars wereused to investigate how nurses would want the medication administration, based on closed loopmedication, to be carried out in the future. The results of the investigation show that nurses havedifferent views of how the future medication administration should be carried out. One significantrisk identified by the nurses is how to maintain an effective workflow when events in the earliersteps prior to administration does not work correctly. Based on the investigation the requirement specification was formulated. One of severalimportant requirements of the future system is that it should be adjustable to the different wardsand their needs. The final conclusion is the following: To make sure that an implementation ofclosed loop medication reaches its full potential, the system must not result in working conditionsmore stressful for nurses.