Global ETD Search

1	Influencing traits before birth Pattinson, Shaun D. January 2000 (has links) No description available. 340
2	Designer Breeds First, Designer Babies Next: How Designer Breeds Paved the Way for Designer Babies and the Future Changes to the World Soto, Evelyn January 2020 (has links) Thesis advisor: Katie Rapier / Through the years, people began to breed their dogs and cats with the intention for the pets to be useful in a certain skill. However, that has shifted to focus on their looks rather than their skills thanks to kennel clubs imposing standards on each breed. This has led irresponsible breeding practices to occur which in turn caused breeds to evolve negatively as breeds began to suffer from preventable genetic disorders and negative physical changes. Genetically manipulating soon shifted from pets to humans with PGD/IVF and CRISPR-Cas9. At first, there was a focus to use these methods to help cure and prevent genetic disorders. That has since shifted to people wanting to create the perfect child. In this thesis I will argue that designer breeds help lead the way to designer babies, and that any genetic manipulation to embryos should only be done if a medical reason is present. / Thesis (BA) — Boston College, 2020. / Submitted to: Boston College. College of Arts and Sciences. / Discipline: Departmental Honors. / Discipline: Philosophy. Bioethics Designer Babies Designer Breeds Philosophy CRISPR-Cas9 Animal ethics
3	Pohled křesťanské etiky na problematiku somatických a germinálních zásahů do lidského genomu za účelem vylepšit parametry druhu Homo Sapiens Sapiens / General view of somatic and germinal interferences with human genome for the purpose of Homo Sapiens Sapiens improvement by means of the Christian ethics HLINÁK, Jiří January 2010 (has links) Substantiality of the thesis is the question of moral and ethic in the sphere of developing genetic and inheritance research. Thesis is especially focused on ethics consequences which result from the application of this research. Thesis is divided in two parts. First part contains general information about genetics science and it is more likely descriptive. This part outlines fundamental principles of genetic, its evolution and genetics breakthroughs and their today exploitation. Thereinafter are mentioned genetics techniques divided in singles areas of interest with main focus on human genetic manipulation {--} main topic of the thesis. Close of this part is dedicated to the theoretical aspects of the ambition in the field of human changing and the description of achieved goals. There are mentioned controlling and regulating mechanisms as conclusions of the first part of the thesis. Opinion on regulation of clerical representatives, civil law, laic public and scientists themselves are referred-to. Second part of the thesis is focused directly on the ethics risks of the practical use of genetic technologies and their impact on human being. The principles of catholic ethic are foreshadowed. The expectations of human genetic improvement are confronted gradually by those principles. [90] Statement, that the human improvement by the genetic manipulation is non tenable by means of the Christian ethics is a conclusion of this thesis.
4	The CRISPR-Cas system Stens, Cassandra, Enoksson, Isabella, Berggren, Sara January 2020 (has links) Derived from and inspired by the adaptive immune system of bacteria, CRISPR has gone from basic biology knowledge to a revolutionizing biotechnological tool, applicable in many research areas such as medicine, industry and agriculture. The full mechanism of CRISPR-Cas9 was first published in 2012 and various CRISPR-Cas systems have already passed the first stages of clinical trials as new gene therapies. The immense research has resulted in continuously growing knowledge of CRISPR systems and the technique seems to have the potential to greatly impact all life on our planet. Therefore, this literature study aims to thoroughly describe the CRISPR-Cas system, and further suggest an undergraduate laboratory exercise involving gene editing with the CRISPR-Cas9 tool. In this paper, we describe the fundamental technical background of the CRISPR-Cas system, especially emphasizing the most studied CRISPR-Cas9 system, its development and applications areas, as well as highlighting its current limitations and ethical concerns. The history of genetic engineering and the discovery of the CRISPR system is also described, along with a comparison with other established gene editing techniques. This study concludes that a deeper knowledge about CRISPR is important and required since the technique is applicable in many research areas. A laboratory exercise will not only inspire but also provide extended theoretical and practical knowledge for undergraduate students. CRISPR CRISPR-Cas system CRISPR-Cas9 genetic engineering genome editing gene editing biotechnology CRISPR classification eukaryotic cells HDR NHEJ double stranded break CRISPR locus spacer acquisition CRISPR delivery RNP dCas9 nCas9 prime editing base editing CRISPRa CRISPRi CRISPR history multiplexing diagnostics gene drive anti-CRISPR designer babies CRISPR ethics. Natural Sciences Naturvetenskap Biological Sciences Biologiska vetenskaper Biochemistry and Molecular Biology Biokemi och molekylärbiologi Genetics Genetik

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