The aim of this thesis is to investigate the effects of JPEG2000 compression on texture feature extraction from digitized mammograms. A partially automated computer aided diagnosis system is designed, implemented, and tested for this analysis. The system is tested on a database of 60 digital mammograms obtained from the Digital Database for Screening Mammography at the University of South Florida. Using JPEG2000, the mammograms are compressed at 20 different compression ratios ranging from 17:1 to 10,000:1. Two approaches to texture feature extraction are investigated: (i) region of interest (ROI), which is a bounding box around the segmented mass and (ii) rubber band straightening transform (RBST), which is a band of pixels around the segmented mass transformed to a rectangular strip. The gray tone spatial dependent matrices are computed from the ROI and the RBST for the original uncompressed mammograms as well as each group of compressed images. Feature selection and optimization is achieved via stepwise linear discriminant analysis. The efficacy of the features is measured using receiver operator characteristic (ROC) curves. The efficacy of the texture features obtained from the original mammograms is compared to those of the compressed mammograms. Overall, the texture feature efficacy was preserved even for relatively high compression ratios. For example, the area under the ROC curve was greater than 0.99 for compression ratios as high as 5000:1, when the RBST method was utilized. Overall, the JPEG2000 compression distorted the RBST texture features lesser than the ROI texture features.

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Today most organizations are doing digital transformations to be more efficient and to offer better service and value. Healthcare is one of those organization that are doing digital transformations and are getting more and more digitalized as a part to be able to for example free more time for taking care of patients and offer better services. However, since healthcare in some point of views differ a bit from other organizations, this also means that they have different challenges when doing a digital transformation. Since healthcare as an organization are regulated by different laws, statutes, and regulations, and in some caseshave a different culture. This creates challenges when developing a digital transformation strategy. And they must consider several aspects such as communication, knowledge,integration, and patient safety when considering a digital transformation. This study aims to investigate these challenges within the healthcare

No mês de outubro de 2007 a Comissão Nacional de Cartografia (CONCAR) lançou uma norma cartográfica composta de especificações técnicas para Estruturação de Dados Geoespaciais Digitais Vetoriais (EDGV) para a realização do mapeamento topográfico sistemático no Brasil. No mês de novembro de 2008 foi publicado o Decreto n 6666, que institui a Infra-Estrutura Nacional de Dados Espaciais e ratifica o uso das normas homologadas pela CONCAR, pelas instituições Federais. Este trabalho realiza dois requisitos, a saber: (a) fornece um esquema relacional alinhado as especificações da EDGV e (b) implementa um protótipo, com vistas a sua utilização no processo de restituição fotogramétrica nas instituições públicas responsáveis pelo mapeamento topográfico no Brasil. A implementação é realizada em ambiente de software livre. Também é importante salientar o caráter educacional da plataforma de software a ser implementada, para que o seu uso seja também direcionado para o ensino teórico e prático da fotogrametria digital nas instituições de ensino e pesquisa. / The National Commission of Cartography (CONCAR) in October 2007 launched a pattern composed of standard specifications for Structuring of Digital Geospatial Data Vector (EDGV) for systematic topographic mapping production in Brazil. In November of 2008 it was published the Decree n 6666, that established the National Spatial Data Infrastructure and ratified the use of standards approved by CONCAR. This work accomplishes two goals: (a) to provide a relational schema specification aligned with the EDGV and; (b) to provide an implementation of a prototype, for using in the photogrammetric restitution of topographic mapping in Brazil. The implementation is performed in an environment of free software, according to the GNU/GPL approch. It is also important to emphasize the educational character of the software to be implemented so that its use is also directed to the theoretical and practical studies of digital photogrammetry in the institutions of education and research.

No mês de outubro de 2007 a Comissão Nacional de Cartografia (CONCAR) lançou uma norma cartográfica composta de especificações técnicas para Estruturação de Dados Geoespaciais Digitais Vetoriais (EDGV) para a realização do mapeamento topográfico sistemático no Brasil. No mês de novembro de 2008 foi publicado o Decreto n 6666, que institui a Infra-Estrutura Nacional de Dados Espaciais e ratifica o uso das normas homologadas pela CONCAR, pelas instituições Federais. Este trabalho realiza dois requisitos, a saber: (a) fornece um esquema relacional alinhado as especificações da EDGV e (b) implementa um protótipo, com vistas a sua utilização no processo de restituição fotogramétrica nas instituições públicas responsáveis pelo mapeamento topográfico no Brasil. A implementação é realizada em ambiente de software livre. Também é importante salientar o caráter educacional da plataforma de software a ser implementada, para que o seu uso seja também direcionado para o ensino teórico e prático da fotogrametria digital nas instituições de ensino e pesquisa. / The National Commission of Cartography (CONCAR) in October 2007 launched a pattern composed of standard specifications for Structuring of Digital Geospatial Data Vector (EDGV) for systematic topographic mapping production in Brazil. In November of 2008 it was published the Decree n 6666, that established the National Spatial Data Infrastructure and ratified the use of standards approved by CONCAR. This work accomplishes two goals: (a) to provide a relational schema specification aligned with the EDGV and; (b) to provide an implementation of a prototype, for using in the photogrammetric restitution of topographic mapping in Brazil. The implementation is performed in an environment of free software, according to the GNU/GPL approch. It is also important to emphasize the educational character of the software to be implemented so that its use is also directed to the theoretical and practical studies of digital photogrammetry in the institutions of education and research.