Thesis (M.S.)--University of Michigan, 1975.

Thesis (M.S.)--University of Michigan, 1975.

Thesis (Ph. D.)--West Virginia University, 2005. / Title from document title page. Document formatted into pages; contains xvii, 295 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references (p. 262-276).

Thesis (doctoral)--Katholieke Universiteit te Nijmegen.

No description available.

Thesis (MScPhysio)--Stellenbosch University, 2008. / ENGLISH ABSTRACT: Acute exacerbation is an important event of COPD as it causes significant disability and mortality. Especially repeated hospitalisation of patients with acute exacerbation has been associated with reduce quality of life and excessive hospitalisation cost. Chronic Obstructive Pulmonary Disease causes significant functional limitations that translate into enormous economic and societal burden. Study Aim: To describe the profile and selected outcomes of Chronic Obstructive Pulmonary Disease (COPD) patients admitted with acute exacerbation to hospitals in the northern suburbs of the Western Cape. Study design: A multicenter retrospective descriptive single subject design was used. Method: Patients admitted with the diagnosis of COPD with acute exacerbation in the time period 01June 2004-01June 2005 were followed up retrospectively for a period of 12 months. The demographics, medical condition on admission and past presentation of acute exacerbation, length of stay in hospital and the number of readmissions for acute exacerbation in the 12 month period were collected and recorded on a self designed data capture sheet. Results: One hundred and seventy eight patients were admitted with acute exacerbation at the three hospitals. The mean age of the patients were 63 (±11.73), more males than females (103: 75) were admitted. Subjects spent a mean of 5.67 (±6.55), days in hospital with every admission and admission frequency of up to eight periods were recorded. Of the n=178 admitted, 56% had one admission and 44% had 2 or more admissions in the study year. This resulted in a total of 338 hospital admissions with the 78 subjects responsible for the majority of admissions (238) Subjects presenting with two or more co-morbidities had a significantly greater risk of multiple re admissions. Subjects with three or more admissions had two or more co morbidities (p=0.001), comparatively those with one admission had only one co morbidity. Congestive cardiac failure (p=0.01) as well as the lack of Long Term Oxygen Therapy p=0.017) were associated with increase risk of three or more admissions. Conclusion: Patients admitted with acute exacerbation to the hospitals where the study was conducted presented with an age ranging from 30-95 years. Patients with 2 or more admissions experience up to eight readmissions episodes in the study year. This is a cause of concern in respect of the burden of disease on especially the younger economically viable South African population. In the current study factors that influenced readmission were the presence of two or more co morbid diseases, specifically the presence of congestive cardiac failure as well as the lack of LTOT. Interventions including a pulmonary rehabilitation programme post discharge should be aimed at decreasing frequency of hospitalisation especially in those patients who are a risk of readmission. / AFRIKAANSE OPSOMMING: Verergering van simptome in Kroniese Obstruktiewe Lugweg Siekte (KOLS) is baie belangrik as gevolg van die ongeskiktheid en mortalitieit wat dit veroorsaak. Dit veroorsaak vermindering in die kwaliteit van lewe en verhoog hospitaal koste verbind met die siekte. Die beperkings toe te skrywe aan die Kroniese Obstruktiewe Lugweg Siekte veroorsaak ontsettende ekonomiese en sosiale druk. Doelstelling: Om die profiel en geselekteerde uitkomste van pasiente met Kroniese Obstruktiewe Lugweg Siekte toegelaat met verergering in die hospitale van die noordelike voorstede van die Wes Kaap te beskryf. Studie ontwerp: ʼn Multisentrum retrospektiewe beskrywende enkel persoon studie. Studie metode: Pasiente toegelaat met verergering van Kroniese Obstruktiewe Lugweg Siekte in die periode 01Junie 2004-01Junie 2005 was retrospektief opgevolg vir ‘n periode van 12-maande. Demografiese data, mediese toestand op toelating en ontslag, lengte van hospitaal verblyf en getal toelatings in die 12- maande was gekollekteer en gedokumenteer op self ontwerpde vorms. Resultate: Een-honderd agt en seventig pasiente was toegelaat met verergering by die drie hospitale. Die gemiddelde ouderdom van die studie populasie was 63 (±11.73) met meer mans as vrouens (103: 75) toegelaat. Die studie populasie het gemiddelde dae van 5.67 (±6.55), in die hospitaal deurgebring en toelating frekwensie van agt episodes was gedokumenteer. Van die n=178 toegelaat was 56% eenkeer toegelaat en 44% het 2 of meer toelatings in die studie jaar gehad. Dit het in 338 hospital toelaatings veroorsaak en 78 van die studie populasie verantwoordelik vir die meeste van die toelatings (238). Die groep met drie of meer toelatings in die studie jaar het twee of meer siektetoestande (p=0.001) gehad, teenorgesteld met die wat net een toelaat was met een siektetoestand. Hart versaaking (p=0.01) en die gebrek aan suurstof by die huis (p=0.017) was verbind met meer risiko van drie of meer toelating. Samevatting: Die ouderdoms verskil was wydbeskrywend van 30-95 jaar van die pasiente wat in die studie jaar toegelaat is by die drie hospitale. Pasiente wat 2 of meer keer toegelaat is het tot agt hertoelatings in die studie jaar gehad. Kommerwekkend is die uitwerking van die siekte op die jonger werkend populasie in Suid Afrika. In die studie was hertoelating beinvloed deur die teenwoordigheid van twee of meer siektetoestande, spesifiek hart versaaking sowel as die gebrek aan suurstof by die huis. Intervensies insluitende pulmonale rehabilitasie na ontslag se doel moet wees om vermindering van heraaldelike hospitalisasie in hoë risiko pasiente vir hospitalisasie.

published_or_final_version / Social Work / Master / Master of Social Work

Thesis (PhD (Sport Science))--Stellenbosch University, 2008. / The benefits of exercise training for patients with chronic obstructive pulmonary disease (COPD) are well-documented. In South Africa, exercise programmes for COPD patients are limited and often expensive and inaccessible to the broader community. The purpose of this study was to assess the responses of COPD patients to an exercise programme and to determine if the same results can be obtained through a less costly programme. In the primary programme of the study, 22 subjects were subjected to 12 weeks of exercise training. Each subject underwent comprehensive pre- and post-intervention assessments, which included the measurement of overall health status by a physician, level of dyspnoea, forced expiratory lung function, exercise capacity, body mass index and health-related quality of life. Exercise sessions included aerobic and strength training exercises and involved three, hour-long exercise sessions a week. In the modified programme, 18 subjects were randomly divided into an experimental and control group. Eleven subjects were included in the experimental group and seven subjects in the control group. Subjects had to complete 32, hour-long exercise sessions in a 10-week period. The experimental group’s exercise programme was adapted so that no specialised equipment was used, while the control group exercised in a well-equipped exercise- and rehabilitation centre.

Thesis (MScSportSc)--University of Stellenbosch, 2004. / ENGLISH ABSTRACT: The purpose of the study was to measure the responses of chronic obstructive pulmonary disease patients to an exercise programme in a South Africa setting. Nine subjects were evaluated before and after aerobic and resistance training three times a week for the total of 12 weeks. Each evaluation measured forced expiratory lung function; health-related quality of life; functional capacity; level of dyspnea; body composition; physician global evaluation; and the patient global evaluation. The exercise programme consisted of one-hour exercise sessions, three times a week for 12 weeks. The exercise sessions included elements of aerobic and resistance training of the upper and lower extremities. Functional capacity improved drastically (p < 0.01), as did the physician and the patient global evaluations (p < 0.01 and p < 0.01, respectively). Levels of dyspnea also improved (p < 0.01). Health-related quality of life improved marginally (p = 0.03). No significant change was noted in lung function and body composition. The study concluded that an exercise programme consisting of aerobic and resistance training improves chronic obstructive pulmonary disease patients' health-related quality of life, functional capacity and levels of dyspnea. Exercise also reduces the symptoms of chronic obstructive pulmonary disease as are perceived by the physician and patient alike. Exercise does not change lung function or body composition of chronic obstructive pulmonary disease patients. Exercise in conjunction with appropriate medical treatment has the potential to benefit all chronic obstructive patients in South Africa. Keywords: COPD, quality oflife, functional capacity, rehabilitation, exercise. / AFRIKAANSE OPSOMMING: Die doel van die studie was om die reaksies te meet van pasiënte met chroniese obstruktiewe pulmonêre siekte op 'n oefenprogram in 'n Suid-Afrikaanse konteks. Nege proefpersone is voor en na aërobiese en weerstandsoefening drie keer per week vir 'n totaal van 12 weke geëvalueer. Elke evaluering het die volgende gemeet: geforseerde ekspiratoriese longfunksie, gesondheidsverwante lewenskwalitiet, funksionele kapasiteit; dispneevlak, liggaamsamestelling; geneesheer algehele evaluering asook pasiënt algehele evaluering. Die oefenprogram het uit een-uur sessies bestaan, wat drie keer per week vir 12 weke plaasgevind het. Die oefensessies het elemente van aërobiese en weerstandsoefeninge van die boonste en onderste ledemate ingesluit. Funksionele kapasiteit het drasties verbeter (p < 0.01), net so ook die geneesheer en pasiënt algehele evaluerings (p < 0.01 en p < 0.01, respektiewelik). Dispneevlakke het ook verbeter (p < 0.01). Gesondheidsverwante lewenskwaliteit het marginaal verbeter (p = 0.03). Geen beduidende veranderinge is in die longfunksie en liggaamsamestelling gevind nie. Die studie het bevind dat 'n oefenprogram wat uit aërobiese en weerstandsoefening bestaan gesondheidsverwante lewenskwaliteit, funksionele kapasiteit asook dispneevlakke van pasiënte met chroniese obstruktiewe pulmonêre siekte verbeter. Oefening verminder ook die simptome van chroniese obstruktiewe pulmonêre siekte soos waargeneem deur beide die geneesheer en pasiënt. Oefening verander ook nie longfunksie of liggaamsamestelling van pasiënte met chroniese obstruktiewe pulmonêre siekte nie. Oefening tesame met die geskikte mediese behandeling kan voordelig wees vir chronies obstruktiewe pasiënte in Suid- Afrika. Keywords: KOPS, lewenskwaliteit, funksionele kapasiteit, rehabilitasie, oefening.

Chung Mei-lan. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2000. / Includes bibliographical references (leaves 118-124). / Abstracts in English and Chinese. / Abstract --- p.i / Declaration --- p.v / Acknowledgment --- p.vi / Abbreviations --- p.viii / List of Figures --- p.x / List of Tables & Graphs --- p.xi / Chapter 1. --- Background --- p.1 / Chapter Chapter 1: --- Age-Associated Changes in Nutritional Status in the Elderly --- p.1 / Chapter 1.1. --- Body Composition --- p.1 / Chapter 1.2. --- Nutritional Requirements --- p.2 / Chapter 1.2.1. --- Energy requirement in the elderly --- p.3 / Chapter 1.2.2. --- Protein requirement in the elderly --- p.3 / Chapter 1.2.3. --- Vitamin and minerals requirement in the elderly --- p.4 / Chapter 1.3. --- Food Intake --- p.4 / Chapter 1.3.1. --- Biobehavioral factors --- p.5 / Chapter 1.3.2. --- Social factors --- p.9 / Chapter 1.3.3. --- Psychological factors --- p.9 / Chapter 1.3.4. --- Physical factors --- p.10 / Chapter 1.3.5. --- Medical factors --- p.10 / Chapter 1.4. --- Age-Related Changes in Gastrointestinal Tract --- p.10 / Chapter Chapter 2: --- Energy Expenditure in the Elderly --- p.12 / Chapter 2.1. --- Total Daily Energy Expenditure (TEE) --- p.13 / Chapter 2.2. --- Basal Metabolic Rate (BMR) --- p.14 / Chapter 2.2.1. --- Mechanisms Leading to a Decrease in FFM Adjusted BMR --- p.15 / Chapter (i) --- Sex --- p.15 / Chapter (ii) --- Sympathetic Nervous System (SNS) Activity --- p.16 / Chapter (iii) --- Physical Activity --- p.17 / Chapter (iv) --- Body Weight --- p.17 / Chapter (v) --- Hormones --- p.18 / Chapter 2.3. --- Diet-Induced Thermogenesis (DIT) --- p.18 / Chapter 2.4. --- Energy Costs of Physical Activity --- p.20 / Chapter Chapter 3: --- Methods for the Measurements of Energy Expenditure --- p.22 / Chapter 3.1. --- Direct Calorimetry --- p.22 / Chapter 3.1.1. --- Principle of Direct Calorimetry --- p.22 / Chapter 3.1.2. --- Isothermal calorimetry --- p.23 / Chapter 3.1.3. --- Gradient-layer direct calorimetry --- p.23 / Chapter 3.1.4. --- Advantages and Disadvantages of Direct Calorimetry --- p.24 / Chapter 3.2. --- Indirect Calorimetry --- p.25 / Chapter 3.2.1. --- Principle of Indirect Calorimetry --- p.25 / Chapter 3.2.2. --- Whole body indirect calorimetry --- p.25 / Chapter 3.2.3. --- "Indirect calorimetry: ventilated hood system, a face mask, or mouthpiece" --- p.26 / Chapter 3.2.4. --- Advantages and Disadvantages of Indirect Calorimetry --- p.27 / Chapter 3.3. --- The Doubly-Labeled Water Method --- p.27 / Chapter 3.3.1. --- Principle --- p.27 / Chapter 3.3.2. --- Advantages and Disadvantages --- p.28 / Chapter 3.4. --- The Labeled Bicarbonate Method --- p.29 / Chapter 3.4.1. --- Principle of Isotope Dilution Method --- p.29 / Chapter 3.4.2. --- Principle of Traditional Labeled HC03 Method --- p.32 / Chapter 3.4.3. --- Labeled Bicarbonate-Urea Method --- p.34 / Chapter I. --- Calculations --- p.35 / Chapter A. --- Determination of energy equivalent of CO2 --- p.35 / Chapter B. --- Relationship between specific activity of urea and specific activity of CO2 --- p.35 / Chapter C. --- Fixation of infused label in the body --- p.36 / Chapter D. --- Calculation of CO2 production from the specific 3 activity of urinary urea --- p.6 / Chapter E. --- Two assumptions in labeled bicarbonate-urea method --- p.36 / Chapter 3.4.4. --- Advantages and Disadvantages of Labeled Bicarbonate-Urea Method --- p.37 / Chapter 3.5. --- Heart Rate Monitoring --- p.37 / Chapter 3.5.1. --- Principle --- p.37 / Chapter 3.5.2. --- Advantages and Disadvantages --- p.38 / Chapter 3.6. --- Activity Monitoring --- p.39 / Chapter 3.6.1. --- Principle --- p.39 / Chapter 3.6.2. --- Advantages and Disadvantages --- p.39 / Chapter 3.7. --- Activity Diaries --- p.40 / Chapter 3.7.1. --- Retrospective activity questionnaires --- p.40 / Chapter I. --- Principle --- p.40 / Chapter II. --- Advantages and Disadvantages --- p.40 / Chapter 3.7.2. --- Current diary method --- p.41 / Chapter I. --- Principle --- p.41 / Chapter II. --- Advantages and Disadvantages --- p.42 / Chapter 3.7.3. --- Time-and-motion study --- p.42 / Chapter I. --- Principle --- p.42 / Chapter II. --- Advantages and Disadvantages --- p.43 / Chapter Chapter 4: --- Nutritional Status and Energy Expenditure in Chronic Obstructive Pulmonary Disease (COPD) Patients --- p.44 / Chapter 4.1. --- Nutritional Status --- p.44 / Chapter 4.1.1. --- Body weight --- p.44 / Chapter 4.1.2. --- Fat-free mass (FFM) --- p.44 / Chapter 4.2. --- REE --- p.46 / Chapter 4.3. --- DIT --- p.47 / Chapter 4.4. --- TEE --- p.47 / Chapter 4.5. --- Nutrition Repletion by Caloric Supplement --- p.48 / Chapter 2. --- Objectives --- p.50 / Chapter 3. --- Subject and Method --- p.51 / Chapter 3.1. --- Part A: Subject and Methods I --- p.51 / Chapter 3.1.1. --- Subjects --- p.51 / Chapter 3.1.2. --- Methods --- p.51 / Chapter I. --- Anthropometric Assessment --- p.51 / Chapter II. --- Nutrient Intake --- p.52 / Chapter III. --- Clinical Assessment --- p.52 / Chapter IV. --- Energy Expenditure --- p.53 / Chapter V. --- Mini Nutritional Assessment Questionnaire --- p.53 / Chapter VI. --- Statistical Analysis --- p.54 / Chapter 3.2. --- Part B: Subject and Methods II --- p.55 / Chapter 3.2. --- Subjects --- p.55 / Chapter I. --- Patients --- p.55 / Chapter II. --- Control subjects --- p.55 / Chapter 3.2.2. --- Methods --- p.56 / Measurement of TEE by Labeled Bicarbonate-Urea Method --- p.56 / Chapter I. --- Study Protocol --- p.56 / Chapter Figure 6: --- Study protocol in Hospital --- p.57 / Chapter II. --- Clinical Protocol --- p.58 / Chapter A. --- Preparing the infusion --- p.58 / Chapter B. --- "Inserting the subcutaneous cannula, and starting the infusion" --- p.58 / Chapter C. --- Urine collection --- p.59 / Chapter D. --- Blood sample --- p.59 / Chapter III. --- Laboratory Procedures --- p.60 / Chapter A. --- Measuring the radioactivity of the infused bicarbonate solution --- p.60 / Chapter B. --- Measuring of specific activity of urea --- p.60 / Chapter (i) --- Titration of hyamine hydroxide solution --- p.60 / Chapter (ii) --- Urine radioactivity quantification --- p.61 / Chapter (1) --- Removal of dissolved CO2 from urine --- p.61 / Chapter (2) --- Determination of specific activity of C02 --- p.62 / Chapter (a) --- Principle --- p.62 / Chapter (b) --- Laboratory procedures for the determination of specific activity of urea --- p.62 / Chapter IV. --- Measurement in Hospital --- p.63 / Chapter A. --- Anthropometry --- p.63 / Chapter B. --- Indirect calorimetry --- p.63 / Chapter (i) --- Principle --- p.63 / Chapter (ii) --- Measurement of REE --- p.64 / Chapter (iii) --- Measurement of DIT --- p.65 / Chapter C. --- Food supply and dietary record during the study --- p.65 / Chapter D. --- Record of physical activity in rehabilitation program --- p.66 / Chapter E. --- Mini Nutritional Assessment Questionnaire --- p.67 / Chapter V. --- Statistical Analysis --- p.67 / Chapter 4. --- Results --- p.68 / Chapter 4.1. --- Results of Part A Study --- p.68 / Chapter 4.1.1. --- Anthropometry --- p.68 / Chapter 4.1.2. --- Nutrient Intake --- p.69 / Chapter 4.1.3. --- Caloric Balance --- p.71 / Chapter 4.1.4. --- Mini Nutritional Assessment Questionnaire --- p.72 / Chapter 4.2. --- Results of Part B Study --- p.73 / Chapter 4.2.1. --- Anthropometric Data --- p.73 / Chapter 4.2.2. --- REE --- p.74 / Chapter 4.2.3. --- DIT --- p.75 / Chapter 4.2.4. --- Nutrient Intake --- p.75 / Chapter 4.2.5. --- TEE --- p.76 / Chapter 4.2.6. --- Caloric Balance --- p.77 / Chapter 4.2.7. --- Mini Nutritional Assessment Questionnaire --- p.77 / Chapter 4.3. --- Table 1-1 --- p.78 / Chapter 4.4. --- Table 2-1 --- p.89 / Chapter 4.5. --- Graph1 --- p.100 / Chapter 5. --- Discussion --- p.103 / Chapter 5.1. --- Anthropometry in COPD patients --- p.103 / Chapter 5.2. --- Caloric and Nutrient intake in COPD patients --- p.105 / Chapter 5.3. --- Resting Energy Expenditure (REE) --- p.107 / Chapter 5.4. --- Diet-Induced Thermogenesis (DIT) --- p.108 / Chapter 5.5. --- Total Daily Energy Expenditure (TEE) --- p.108 / Chapter 5.6. --- Caloric Balance --- p.109 / Chapter 5.7. --- Limitation of this Study --- p.112 / Chapter 5.7.1. --- 24-hrs dietary recall --- p.112 / Chapter 5.7.2. --- Bicarbonate-urea method --- p.113 / Chapter 5.7.3. --- Anthropometry of community healthy elderly --- p.113 / Chapter 5.8. --- Recommendations --- p.114 / Chapter 5.8.1. --- Anthropometry monitoring in COPD patients --- p.114 / Chapter 5.8.2. --- Caloric supplements --- p.114 / Chapter 5.8.3. --- Physical activity in COPD patients --- p.115 / Chapter 6. --- Conclusions --- p.117 / Chapter 7. --- References --- p.118 / Chapter 8. --- Appendix I --- p.125 / Chapter A. --- Calculation of Total Energy Expenditure (TEE) --- p.125 / Chapter B. --- Sample of Calculation of Total Energy Expenditure (TEE) in Part B of the Study --- p.129 / Chapter 9. --- Appendix II - Equations --- p.133 / Chapter 10. --- Appendix III - Flow Calibration --- p.136