While obstructive sleep apnea among children with Down syndrome is very common, the pre-existing risk factors and its impact to neurodevelopment are not well known. The aims and objectives of this systematic review are to determine the prevalence of OSA among DS children and to identify the associated risk factors. 6 articles that met the inclusion criteria were retrieved after using PubMed and Google Scholar in literature searching. The prevalence of OSA has great variation among different countries but are relatively high, ranging from 57% to 79%. OSA was significant associated with obesity, age and tonsil size. It is also known to associate with behavioral problem in DS children and delay their neurodevelopment. Therefore, early treatment followed by appropriate modification in lifestyle and diet is crucial in managing OSA. / published_or_final_version / Public Health / Master / Master of Public Health

published_or_final_version / abstract / Physiology / Doctoral / Doctor of Philosophy

This study shows that William Faulkner's Go Down, Moses is a unified prose narrative. The various themes in this book are patterned so that they tie the work's seven chapters together into a coherent whole. Because of the thematic complexity of this book, only one set of themes, the acceptance or rejection of love and understanding, is examined. Characters demonstrate their acceptance of these values through their association with traditionally successful families. Characters reveal their rejection of these values through their association with unsuccessful families, if they are connected with families at all. Since literary criticism has no terminology for describing thematic patterning, this study employs terms used in musical composition. By constructing a model similar to the fugue form in music, we can show how the acceptance or rejection of love and understanding functions as one of the unifying elements in Go Down, Moses. The musical fugue has two parts, the exposition and the development. In the exposition, the fugue's major theme, called the subject, is introduced. In counterpoint to the subject, the fugue's minor theme, the countersubject, is also introduced. The full exploration of the subject and the countersubject's thematic possibilities is the province of the fugue's development. Between the sections of the development are short passages called episodes, in which portions of the subject and countersubject are used to shift the fugue's thematic emphasis. Finally, fugues often have a short, concluding section, the coda, in which there is a thematic summation. In the fugue-analog model for Go Down, Moses, the rejection of love and understanding corresponds to the subject, the major theme of the fugue. The acceptance of these values corresponds to the countersubject, the minor theme of the fugue. The fugal counterpoint is achieved through the actions of the book's characters in relation to successful and unsuccessful families. We can describe "Was," Chapter One of Go Down, Moses, as the exposition of the fugue-analog. The subject is developed through the actions of the McCaslin twins and Sophonsiba Beauchamp and through the initial three paragraph description of Isaac McCaslin. The countersubject appears through the actions of Tomey's Turl. "The Fire and the Hearth," Chapter Two, becomes the first section of the fugue-analog's development. The subject is seen through much of Lucas Beauchamp's activities as well as those of Roth Edmonds. The countersubject arises out of Lucas's loyalty to his family. This developmental section ends on the countersubject. "Pantaloon in Black," Chapter Three of Go Down, Moses, corresponds to the episode of the fugue-analog. Rider's strong attachment to his dead wife presents the countersubject, while the portrait of the marriage of the deputy sheriff develops the subject. The fugue-analog's episode shifts the thematic emphasis from countersubject to subject in preparation for the second section of development. The Isaac McCaslin chapters, "The Old People," "The Bear," and "Delta Autumn," are the fugue-analog's second development sections. Isaac's unsuccessful relations with his wife, his black cousins, and Cass Edmonds develop the subject, while Isaac's successful relationship with Sam Fathers presents the countersubject. The emphasis of this section of Go Down, Moses is on the subject. The book ends with "Go Down, Moses," the last chapter, which corresponds to the fugue-analog's coda. By ending with the description of the successful "family" of Miss Worsham and Molly Beauchamp, Go Down, Moses ends on the countersubject.

No description available.

No description available.

In the present study, performance on a range of mathematical reasoning and number processing tasks was assessed across two syndrome groups for which numerical ability is under-researched: Fragile X syndrome and Down syndrome. Given the paucity of current research, it was unknown whether all aspects of arithmetic and number processing would be globally affected across groups or whether there would be syndrome specific proficiencies and deficiencies. Statistical analysis revealed that males with fragile X syndrome performed significantly worse on all tasks even when performance was compared to typically developing children of a similar developmental level. However, when performance was compared to children with Down syndrome differing profiles emerged, with greater weaknesses by the fragile X syndrome males on specific tasks requiring mental arithmetic and basic numeracy skills. The importance of using syndrome specific information in the assessment of math disabilities and the design of early educational interventions are discussed.

Presentación de trabajo semestral para el curso ME50 2009-1.

There has been a significant increase in the number of Down Syndrome (DS) births over the past 3 decades in South Africa. This means there are increasingly more mothers, children with DS and family members experiencing the stressors associated with the condition. However, the increase in DS births has led to the advancement of related medical and educational interventions, resulting in more families with a child with DS overcoming these stressors and discovering the positive aspects of having a child with DS. This study aimed to uncover these positive aspects by exploring the positive experiences of a sample of mothers of a child with DS, with the hope that the findings will help society to move away from its focus on the stressors of having a child with DS to instead concentrating on the many ways in which families can cope with these stressors. As part of the research process, face-to-face interviews were conducted as a qualitative approach to gain an in-depth understanding of this research topic. The interviews were all recorded by means of a tape recorder. There is only one hospital in the Western Cape Metropole area that specialises in this condition, and that hospital was consequently selected as the location for this research, since all mothers of children with DS are referred to this hospital. A purposive sampling method and the criterion sampling strategy were used for the selection of these five mothers with whom interviews were conducted in the hospital’s developmental clinic The main findings of the research include both the difficult and positive experiences of being a mother of a child with DS. Two of the major themes that arose in terms of the difficult experiences were: (1) having to make many adjustments to one’s life to accommodate unpredictable health implications, developmental delays, negative perceptions, and unprofessional conduct; and (2) the difficulty of dealing with emotions, emotions of: fear, aloneness, and grieving. The mothers’ positive experiences generally developed out of their attempts to find coping mechanisms for the above challenges, and these positives centre on support, resources, faith in God, accepting the condition, a positive attitude and bonding with their child with DS. The predominant finding in terms of participants’ own recommendations for new mothers of a child with DS was for them to learn to accept the condition. Other findings addressing ways of coping with the condition were as follows: persevering, being hopeful, taking it one day at a time, having awareness and understanding of the diagnosis, being around positive people, attending regular appointments, seeking out guidance and support for your child’s development, loving your child, enjoying your child, and being present in every moment. / Thesis (MSW (Forensic Practice))--North-West University, Potchefstroom Campus, 2013

There has been a significant increase in the number of Down Syndrome (DS) births over the past 3 decades in South Africa. This means there are increasingly more mothers, children with DS and family members experiencing the stressors associated with the condition. However, the increase in DS births has led to the advancement of related medical and educational interventions, resulting in more families with a child with DS overcoming these stressors and discovering the positive aspects of having a child with DS. This study aimed to uncover these positive aspects by exploring the positive experiences of a sample of mothers of a child with DS, with the hope that the findings will help society to move away from its focus on the stressors of having a child with DS to instead concentrating on the many ways in which families can cope with these stressors. As part of the research process, face-to-face interviews were conducted as a qualitative approach to gain an in-depth understanding of this research topic. The interviews were all recorded by means of a tape recorder. There is only one hospital in the Western Cape Metropole area that specialises in this condition, and that hospital was consequently selected as the location for this research, since all mothers of children with DS are referred to this hospital. A purposive sampling method and the criterion sampling strategy were used for the selection of these five mothers with whom interviews were conducted in the hospital’s developmental clinic The main findings of the research include both the difficult and positive experiences of being a mother of a child with DS. Two of the major themes that arose in terms of the difficult experiences were: (1) having to make many adjustments to one’s life to accommodate unpredictable health implications, developmental delays, negative perceptions, and unprofessional conduct; and (2) the difficulty of dealing with emotions, emotions of: fear, aloneness, and grieving. The mothers’ positive experiences generally developed out of their attempts to find coping mechanisms for the above challenges, and these positives centre on support, resources, faith in God, accepting the condition, a positive attitude and bonding with their child with DS. The predominant finding in terms of participants’ own recommendations for new mothers of a child with DS was for them to learn to accept the condition. Other findings addressing ways of coping with the condition were as follows: persevering, being hopeful, taking it one day at a time, having awareness and understanding of the diagnosis, being around positive people, attending regular appointments, seeking out guidance and support for your child’s development, loving your child, enjoying your child, and being present in every moment. / Thesis (MSW (Forensic Practice))--North-West University, Potchefstroom Campus, 2013

The Worldwide Interoperability for Microwave Access, or WiMax, is a wireless communication technique based on IEEE 802.16 standards. Its advantage of sending high data rates over long distances, while using a single base station to cover a large area, has made this technique a flexible and reliable solution for public wireless networks. WiMax has two main types of networks: Fixed and Mobile. The most popular transceiver used in WiMax applications is the “Direct-Conversion Architecture” due to its high level of integration and less component requirements, which leads to reduced power dissipation. In Direct Conversion Architecture, the mixer is a key block in the transceiver chain. Depending on design specifications and constraints, different types of mixers may be considered. However, the most appropriate down converter mixer for WiMax applications is the Gilbert-cell mixer. This thesis will then explore the design of a down converter Gilbert-Cell Mixer within the realm of Fixed WiMax technology. This design was achieved in the commercial circuit simulator Advanced Design System (ADS) using the 0.15mm InGaAs pHEMT technology process provided by Win Semiconductor Crop.