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Business use of branding strategies for e-commerce benefitsOnojaefe, Darlington Peter January 2008 (has links)
Thesis submitted in fulfilment of the requirements for the degree
Doctor of Technology: Marketing
in the Faculty of Business
at the Cape Peninsula University of Technology, 2008 / This thesis identifies and examines evidence of e-commerce in three large businesses (Woolworths, Momentum and Santam) focusing on their Internet branding strategies, the impact of management actions and how those actions contribute to e-commerce success. Case study was used to assemble evidence from the three companies. The data received from respondents were transcribed, codified into thirteen key words. These were analysed using Cohen Kappa method of content analysis. The findings show different impact of management actions and prioritisation of management functions are evident at different stages of the adoption process. In addition, the application of management function differs at different stages suggesting expected changes in management competency as the adoption process matures.
This thesis argues that as we move to a more interactive mode of working with customers and competitors using Internet technology, the role of marketing is critical; within marketing, brand management is seen as a particularly important activity. The work reported is based on the evidence that brand management is indeed important, and a maturity model is presented to guide brand management activities at different stages of e-commerce adoption. Internet-related partnering opportunities with large firms remain a concern for smaller firms. It reveals that although much Internet research has taken a technical viewpoint, some experts have begun to make connections between Internet success and brand management.
This thesis shows that there are opportunities for businesses doing e-commerce but, sufficient attention should be given to the implementation of branding and brand management strategies that recognise the changes and challenges of e-commerce adoption. It also shows that the patterns of management activities and actions that will ensure success are much clearer, as well as the partnering opportunities with small businesses.
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The utilisation of change management in non-profit organisations: a business necessityKondi Kondi, Jordan January 2013 (has links)
RESEARCH THESIS
Submitted in fulfilment
of the requirements for the degree
DOCTOR TECHNOLOGIAE:
Human Resource Management
In the faculty of
Business
CAPE PENINSULA UNIVERSITY OF TECHNOLOGY
2013 / A sizeable number of individuals and organisations are not keen to invest or donate significant amounts of cash in non-profit organisations (NPOs) since the results of their donations or investment cannot always be shown or substantiated. Thus, changing from a traditional non-governmental organisation (NGO) to a social enterprise seems to be the only ‘bail-out’ for NPOs should they wish to sustain and maintain their activities.
This study investigated the possibility of utilising change management as a tool for NGOs wishing to transition from traditional to social enterprises. The objective was to assess how change management models initially developed for profit/business organisations, could effectively be applied in NPOs.
In order to assess the suitability of these models, the study used two types of research methods. The first was theoretical and took the form of a literature review. The second was empirical and was held in the field (experimental). In addition to the consultation of secondary data and the field experiment, the study used other research tools which were: interviews, focus group discussion, direct observation and survey questionnaires.
The study found that change management principles developed for profit organisations are also suitable for NPOs, however, certain adaptations are needed to ensure successful implementation of change initiatives in this sector.
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Development of decomposition methods for solution of a multiarea power dispatch optimisation problemKrishnamurthy, Senthil January 2013 (has links)
Thesis submitted in fulfilment of the requirements for the degree
Doctor of Technology: Electrical Engineering
in the Faculty of Engineering
at the Cape Peninsula University of Technology
2013 / The objective of the economic dispatch problem of electrical power generation is to schedule the committed generating unit outputs to meet the required load demand while satisfying the system equality and inequality constraints. The thesis formulates single area and multi-area Combined Economic Emission Dispatch (CEED) problem as single criterion, bi-criterion and multi-criteria optimisation problems based on fuel cost and emission criterion functions, constraints over the operational limits of the generator and the tie-lines, and requirements for a balance between the produced power and the system demand and power loss.
Various methods, algorithms and softwares are developed to find solution of the formulated problems in single area and multi-area power systems. The developed methods are based on the classical Lagrange's and on the meta-heuristic Particle Swarm Optimisation (PSO) techniques for a single criterion function. Transformation of the bi-criteria or multi-criteria dispatch problem to a single criterion one is done by some existing and two proposed in the thesis penalty factors.
The solution of the CEED problems is obtained through implementation of the developed software in a sequential way using a single computer, or in a data-parallel way in a Matlab Cluster of Computers (CC). The capabilities of the developed Lagrange's and PSO algorithms are compared on the basis of the obtained results. The conclusion is that the Lagrange's method and algorithm allows to receive better solution for less computation time. Data-parallel implementation of the developed software allows a lot of results to be obtained for the same problem using different values of some of the problem parameters.
According to the literature papers, there are many algorithms available to solve the CEED problem for the single area power systems using sequential methods of optimisation, but they consume more computation time to solve this problem. The thesis aim is to develop a decomposition-coordinating algorithm for solution of the Multi Area Economic Emission Dispatch (MAEED) problem of power systems. The MAEED problem deals with the optimal power dispatch inside and between the multiple areas and addresses the environmental issue during the economic dispatch. To ensure the system security, tie-line transfer limits between different areas are incorporated as a set of constraints in the optimisation problem. A decomposition coordinating method based on the Lagrange's algorithm is developed to derive a set
of optimal solutions to minimize the fuel cost and emissions of the multi-area power systems.
An augmented function of Lagrange is applied and its decomposition in interconnected sub problems is done using a new coordinating-vector. Task-parallel computing in a Matlab Cluster is used to solve the multi-area dispatch problem. The calculations and tasks allocation to the Cluster workers are based on a shared memory architecture. Implementation of the calculation algorithm using a Cluster of Computers allows quick and simpler solutions to the multi-area CEED problem.
The thesis applied the developed algorithms for the various problem formulation scenarios, i.e. fuel cost and emission function with and without valve point loading effect, quadratic and cubic fuel cost and emission functions. The various IEEE benchmark models are used to test the developed Lagrange's and PSO algorithms in the sequential, data-parallel, and task-parallel implementations.
Developed methods, algorithms and software programmes can be applied for solution of various energy management problems in the regional and national control centres, smart grid applications, and in education and research institutions.
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Analysis of greenhouse gas emission from reactive materials and its thermodynamicsLebelo, Ramoshweu Solomon January 2013 (has links)
Thesis (DTech(Mechanical Engineering))--Cape Peninsula University of Technology, 2013 / The environment is polluted by many gases of which carbon dioxide is one of them and unfortunately during the emission of carbon dioxide, oxygen, which is very important for keeping all species alive, is depleted. Increased industrial activities led to more emission of carbon dioxide and ultimately global warming arose as a result of the greenhouse effect. Global warming has resulted with high temperatures and carbon dioxide production in the atmosphere and it was necessary to come up with mathematical modelling to investigate processes that may try to reduce temperature rise, carbon dioxide emission and oxygen depletion in a stockpile of combustible material. The work done in this thesis considered three differential equations, first for temperature behaviour, second for oxygen depletion and third for carbon dioxide emission. The three equations were solved simultaneously for a reactive slab of combustible material. An exothermic reaction in a stockpile of combustible material results due to the reaction of oxygen with reactive hydrocarbon material and the products are usually heat and carbon dioxide. A detailed discussion on this part is given in chapter 1, and also some definitions of terms applied in this work, together with literature review, statement of problem, aim of the study, objectives of the study and methodology are part of the chapter. In chapter 2, the nonlinear partial differential equations governing the process are derived.
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Analysis laminar flow, thermal stability, and entropy generation in porous channelEegunjobi, Adetatayo Samuel January 2013 (has links)
Thesis submitted in fulfillment of the requirements for the degree
Doctor of Technology: Mechanical Engineering
Cape Peninsula University of Technology, 2013 / Fluid flow through a porous channel and cylindrical pipe walls are important area
of research due to its wide applications in transpiration cooling, gaseous diffusion
technology, cooling of rocket, mechanized irrigation and filtration processes. It is
therefore necessary to examine the effect of Navier slip, combined effects of buoyancy
forces and variable viscosity on the entire flow structure. Analyzing the magneto-
hydrodynamics (MHD) of unsteady flow with buoyancy effect and also investigate
numerically the entropy generation in an unsteady flow through porous pipe. We
have also examined the thermal stability and entropy generation in the system. The
problems were investigated theoretically using appropriate mathematical models for
both transient and steady state scenario. Both analytical techniques and numerical
methods are employed to tackle the model nonlinear equations derived from the law
of conservation of mass, momentum and energy balance.
Some definitions of terms to come across and introduction to fluid flow are given in
chapter 1, together with literature reviews, statement of problem and objectives of
the study.
Chapter 2 lays the foundation for basic fundamental equations governing fluid flow.
In chapter 3, the combined effect of suction/injection and asymmetric Navier slip on
the entropy generation rate for steady flow of an incompressible viscous fluid through a porous channel subjected to different temperature at the walls are investigated.
Chapter 4 analyze combined effects of buoyancy forces together with Navier slip on
the entropy generation in a vertical porous channel wall with suction/injection wall.
Analysis of MHD unsteady flow through a porous pipe with buoyancy effects are
carried out in chapter 5, while chapter 6 investigates numerically entropy generation
of unsteady flow through a porous pipe with suction and chapter 7 gives concluding
remarks.
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E-government implementation for inter-organisational information sharing: a holistic information systems approach for developing countriesRuhode, Ephias January 2013 (has links)
Thesis submitted in fulfilment of the requirements for the degree
Doctor of Technology: INFORMATION TECHNOLOGY
in the Faculty of Informatics and Design
at the Cape Peninsula University of Technology, 2013 / Governments throughout the world are increasingly under pressure to transform in response to rapid changes in the global economy. They are faced with new and challenging situations as the social world, the economy, demography and technology keep changing. While literature reports some degree of success towards e-government implementation in the developed world, there is lack of empirical research on successes of e-government and information sharing practices of government agencies in developing countries. Designers of e-government solutions in all countries face challenges that are unique to their specific sociocultural, economic, geographic, environmental, political, and technical context. However, the peculiarity of e-government challenges is more evident in developing countries than in developed ones.
This research is motivated by the need to investigate an e-government phenomenon in a developing country context like Zimbabwe which is characterised by complex dynamics rooted in politics, economy and social setting. Emphasis is placed on the political nature and the complex institutional environments in which e-government develops and recognition is given to the key concepts of e-government which involve the technological and social aspects.
This study has been scoped empirically to explore e-government implementation efforts at government level then a case study of the Ministry of Tourism and Hospitality’s e-Administration dimension of e-government, with focus on information sharing. Tourism is an example that e-government’s parameters do not stop at the boundaries of the public sector. The research first conducted a document study of all policies and programmes initiated by the government of Zimbabwe towards public sector modernisation using ICTs. Secondly, in order to identify the status of e-government and information sharing as well as government’s vision in the same, interviews were conducted with the Ministry of ICT’s administration. Thirdly, a case study of the Ministry of Tourism and Hospitality was conducted to establish the extent and tools of information sharing between the ministry and other line ministries, departments and
other institutions nationally and internationally. Data from the case were analysed using the Activity-Driven Needs Analysis (ADNA). Research findings from all activities have been discussed and further developed in two solutions-oriented focus group meetings with senior managers at both ministries of ICT and tourism in the area of cross-government information sharing, and in feedback sessions with research participants.
Literature review, analysis of ICT policy documents and case study analysis were insights which underpinned the development of an e-government framework for developing countries. The emphasis of the framework is for e-government designers to place importance on political and institutional factors ahead of any other determinant. Consistent with ADNA and the critical realist perspective, the aim is not to influence these political and institutional factors, but to understand their modus operandi and hence to construct an e-government solution which recognizes the dictates of all stakeholders.
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Modulation of the redox status, phase 2 drug metabolizing enzymes and fumonisin-induced cancer promotion in rat liver by selected Southern African medicinal plantsHikuam, Willem Christoph January 2014 (has links)
Thesis submitted in fulfilment of the requirements for the degree
Doctor of Technology: Biomedical Technology
in the
Faculty of Health and Wellness Sciences
at the
Cape Peninsula University of Technology
2014 / According to the World Health Organization, cancer is the leading cause of death in the
developed world, while it is the second leading cause of death in the developing world. In
particular, liver cancer is the fifth most commonly diagnosed cancer in men, however, it is
the second most frequent cause of death, responsible for an estimated 700,000 deaths
annually. General limited access to health services, including treatment and the overall
management of cancer in developing countries often contribute to the increased mortality
rates when compared to developed countries. For centuries, medicinal plants have been
used to prevent, and to a certain extent, treat cancer as a readily available and affordable
alternative. In many instances, the curative or preventative claims still remain anecdotal.
However, increasing evidence suggest that polyphenolic components of plants possess
antioxidant activities, which are credited with curative/beneficial properties of medicinal
plants. The curative properties could either be related to the primary compounds present in
the plant itself, or the bio-activation products of plant components affecting hepatic drug
metabolising and antioxidant enzymes systems related to carcinogen metabolism and
maintaining oxidative homeostasis, respectively. Similarly, chronic consumption of medicinal
plants could also result in hepatotoxicity, either caused by the primary plant components or
bio-activation products. Due to these observations it is paramount to understand the
mechanisms involved in the metabolism of plant components to critically assess beneficial
versus potential harmful properties associated with chronic consumption.
The focus of the current study was aimed at elucidating the bio-activity of four multipurpose
indigenous plants to Southern Africa, i.e. Adansonia digitata, Agathosma betulina,
Siphonochilus aethiopicus and Myrothamnus flabellifolius. Traditionally, A. digitata has been
used as an immunostimulant, anti-inflammatory and analgesic agent, while also as an
antipyretic agent in the treatment of diarrhoea and dysentery. Similarly, traditional medicinal
uses of A. betulina include treatment cholera, haematuria, calculus, kidney diseases, as well
as infections of the bladder, urethra, and prostate among others. S. aethiopicus was
traditionally employed to treat infections associated with pains and fevers, whereas
M. flabellifolius served as treatment of conditions ranging from respiratory ailments,
backache, kidney problems, haemorrhoids, chest pain, and asthma.
In the first part of this study, the polyphenolic contents and antioxidant capacities of the four
plants were characterised. The emphasis was placed on using different solvents, namely
water, ethanol and acetone for the extraction of the plant material and different
methodologies to assess the antioxidant contents and -capacities of the various extracts as
both these factors can influence the outcome. When considering the antioxidant contents,
total polyphenols, flavanols, and flavonols of the different solvent extracts prepared from the
four plants were determined, whereas three different assays were used for the antioxidant
capacities, i.e. oxygen radical absorbance capacity (ORAC), trolox equivalent antioxidant
capacity (TEAC) and ferric-reducing antioxidant power (FRAP) assays. The A. digitata
acetone extract had the highest (7.121 mg gallic acid equivalent (GAE)/milligram (mg)
soluble solids), whereas the water extract of the same plant had the lowest total phenolic
content (0.008 mg GAE/mg soluble solids). In general, the acetone extracts demonstrated
the highest total polyphenol, flavanol, and flavonol contents, followed by the ethanol extracts,
with the water extracts having the lowest contents. M. flabellifolius was the only distinct
deviation from this rule, where the water extract demonstrated the highest total polyphenol
content. Considering antioxidant capacities, the acetone extracts provided the highest
antioxidant capacities for all plants when assessed using the TEAC (8.56-32.68 milimole
(mmole) trolox equivalent (TE)/mg soluble solids) and FRAP (5.69-37.39 mmole ascorbic
acid equivalent/mg soluble solids) antioxidant assays, with the exception of M. flabellifolius
where the water extract demonstrated the highest activity (22.73 mmole ascorbic acid
equivalent/mg soluble solids). Antioxidant capacity determinations with TEAC and FRAP
assays followed similar patterns, which were different from capacities determined by the
ORAC (0.46-533.54 mmoleTE/mg of soluble solids) assay. Corroborating the antioxidant
content findings, the acetone extracts also demonstrated the highest antioxidant capacities
(140.41-533.54 mmoleTE/mg of soluble solids), followed by ethanol (94.62-151.29
mmoleTE/mg of soluble solids) and water (0.46-134.02 mmoleTE/mg of soluble solids). Only
M. flabellifolius (TEAC and FRAP) and S. aethiopicus (FRAP) deviated from this trend.
Correlations between the polyphenolic contents and antioxidant capacities indicated that
acetone and ethanol were more effective in extracting polyphenolic compounds than water,
while also providing extracts with superior antioxidant activities. Furthermore, ORAC assay
was the antioxidant capacity determining assay of choice for the aqueous plant extracts,
whereas the TEAC and FRAP assays were more suitable when determining the antioxidant
capacities of the acetone and ethanol plant extracts. These results confirm the notion that no
single assay can comprehensively determine the antioxidant activities of plant extracts and
that a battery of assays should be used, as the various antioxidant capacity determination
techniques use different substrates with different targets for measurement.
The second part of this study comprised an in vivo experimental animal model to assess the
potential toxicity, antioxidant status and modulation of the hepatic phase 2 drug metabolising
enzymes following chronic consumption of the various plant extracts in male Fisher rats.
Rats consumed aqueous extracts of the various plants (2% and 5% (w/v)) as the sole source
of drinking fluid for 90 days, and the serum chemical pathology parameters for monitoring
liver and kidney function conducted. These included alkaline phosphatase (ALP), aspartate
transaminase (AST), alanine transaminase (ALT), total iron (Fe), and creatinine (CREA).
Parameters for blood and hepatic redox status included total polyphenols, ORAC, reduced
glutathione (GSH), oxidised glutathione (GSSG), their ratio (GSH:GSSG), conjugated dienes
(CD) and thiobarbituric acid reactive substances (TBARS). Assessment of the phase 2
hepatic xenobiotic metabolising enzymes included glutathione S-transferase (GST) and
activity in the cytosolic fraction and, UDP-glucuronosyltransferase (UDP-GT) activity in
liver microsomes. When considering the liver and kidney function none of the plant extracts
induced any significant toxicity, while 2% A. digitata significantly increased serum Fe. When
considering the redox status, the whole blood and liver samples yielded similar results, with
significant decreases in oxidised glutathione (GSSG) in rats consuming the 2% M.
flabellifolius (82.76 mole/L) and 5% A. digitata (90.42 mole/L) with a resultant significant
increase in the glutathione redox status (GSH:GSSG ratio of 5.69 and 5.64, respectively)
when compared to rats consuming water (4.77). The GSH:GSSG ratio was also significantly
increased by consumption of 2% A. betulina (8.45) and 5% S. aethiopicus (5.99). The
consumption of all plant extracts, except 5% A. betulina and M. flabellifolius, significantly
increased lipid peroxidation in the plasma CDs assay. These results indicated an increased
antioxidant capacity in the liver with/without an associated reduced cellular oxidative stress
status, which could be interpreted as a reduced susceptibility to oxidative damage. When
considering the phase 2 hepatic enzymes, none of the plant extracts caused any significant
changes in GST, GST or UDP-GT activities.
The third part investigated the chemoprotective properties against cancer promotion in the
liver utilising diethylnitrosamine (DEN) as cancer initiator and maize culture material of
Fusarium verticillioides, containing the fumonisin B mycotoxins, as promoters in male
Fischer rats. The rats consumed 2% (w/v) aqueous extracts of A. digitata, A. betulina, and
S. aethiopicus over 28 days after cancer initiation and liver sections subjected to
glutathione-S-transferase placental form positive GSTP+ staining and pre-cancerous liver foci
categorised according to size. In addition, blood and liver analyses were done as described
in the chronic feeding study above. Consumption of the A. digitata and, to a certain extent,
S. aethiopicus extracts, altered the oxidative stress status in the liver as indicated by the
increased lipid peroxidation, as determined by significantly increased liver CDs and the
decreased GSH:GSSG ratio in the blood. This can be related to a subchronic toxicity due to
the high total polyphenol intake as mentioned above. These underlying sub chronic toxic
effects of A. digitata and S. aethiopicus are likely to be responsible for the observed
inhibitory effect on the proliferation of GSTP+ minifoci in the liver. Hepatic phase 2
metabolising enzyme activities were not significantly altered by A. digitata and S. aethiopicus
consumption, while GST activity was significantly increased by A. betulina treatment.
Based on the findings of the current study, aqueous extracts of A. digitata, A. betulina, and
S. aethiopicus may serve as hepatoprotectors with a potential to modulate liver
carcinogenesis, specifically cancer promotion. To our knowledge, no other studies have
attempted to describe the possible chemoprevention mechanisms of these indigenous
medicinal plants. Assessments of phase 1 hepatic enzymes and other antioxidant enzymes
are suggested for future studies to further describe biochemical and molecular mechanisms
associated with consumption of these extracts. Additionally, identifying main compounds
present in the plant extracts could culminate in development of drugs and novel
nutraceuticals. It is also recommended that increasing concentrations of the plant extracts
and/or the ethanol extracts to be used in future studies to better describe dose-responses of
the different plants in liver carcinogenesis.
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Exploitation of the potential of a novel bacterial peroxidase for the development of a new biocatalytic processMusengi, Amos January 2014 (has links)
Thesis submitted in partial fulfilment of the requirements for the degree
Doctor of Technology: Biomedical Technology
In the Faculty of Health and Wellness Sciences
At the Cape Peninsula University of Technology
2014 / Peroxidases are ubiquitous catalysts that oxidise a wide variety of organic and inorganic compounds employing peroxide as the electron acceptor. They are an important class of oxidative enzymes which are found in nature, where they perform diverse physiological functions. Apart from the white rot fungi, actinomycetes are the only other known source of extracellular peroxidases. In this study, the production of extracellular peroxidase in wild type actinomycete strains was investigated, for the purpose of large-scale production and finding suitable applications.
The adjustment of environmental parameters (medium components, pH, temperature and inducers) to optimise extracellular peroxidase production in five different strains was carried out. Five Streptomyces strains isolated from various natural habitats were initially selected for optimisation of their peroxidase production. Streptomyces sp. strain BSII#1 and Streptomyces sp. strain GSIII#1 exhibited the highest peroxidase activities (1.30±0.04 U ml-1 and 0.757±0.01 U ml-1, respectively) in a complex production medium at 37°C and pH 8.0 in both cases. Maximum enzyme production for Streptomyces strain BSII#1 was obtained in the presence of 0.1 mM veratryl alcohol or pyrogallol, while 0.1 mM guaiacol induced the highest peroxidase production in Streptomyces sp. strain GSIII#1.
As the highest peroxidase producer, Streptomyces sp. strain BSII#1 was selected for further studies. The strain was first characterised by a polyphasic approach, and was shown to belong to the genus Streptomyces using various chemotaxonomic, genotypic and phenotypic tests. Production of peroxidase was scaled up to larger volumes in different bioreactor formats. The airlift configuration was optimal for peroxidase production, with Streptomyces sp. strain BSII#1 achieving maximum production (4.76±0.46 U ml-1) in the 3 l culture volume within 60 hrs of incubation.
A protocol for the purification of the peroxidase was developed, which involved sequential steps of acid and acetone precipitation, as well as ultrafiltration. A purification factor of at least 46-fold was achieved using this method and the protein was further analysed by LC-MS. The protein was shown to be a 46 kDa protein, and further biochemical characterisation showed that the peroxidase had a narrower spectrum of substrates as compared to reports on other peroxidases derived from actinomycetes. With 2,4-dichlorophenol as the substrate, the Km and Vmax for this enzyme were 0.893 mM and 1.081 μmol min-1, respectively. The purified peroxidase was also capable of catalysing coupling reactions between several phenolic monomer pairs.
Overall, the peroxidase from Streptomyces sp. strain BSII#1 could feasibly be produced in larger scales and there remains further room to investigate other potential applications for this enzyme.
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Compression and Doppler ultrasound of deep vein thrombosis in patients on tuberculosis treatmentBrock, Sheila Anne January 2013 (has links)
Thesis submitted in fulfilment of the requirements for the degree of
Doctor of Technology: Radiography in the Faculty of Health and Wellness Sciences at the Cape Peninsula University of Technology
2013 / Background. Ultrasound has until recently been regarded as a sophisticated examination reserved for tertiary health care. In reality it is well suited to the district or primary health-care situation. A DVT (deep vein thrombosis) is an important complication of the treatment of TB and this can lead to more devastating sequelae such as a pulmonary embolus. Many DVTs are clinically silent, making the diagnosis difficult.
Method. This study was a prospective, longitudinal observational study. The study documented the incidence of DVTs and their onset, assessed certain aspects in an attempt to identify some risk factors, and noted the most common position of the DVT in a TB population. The feasibility of a sonographer-led ultrasound clinic for the diagnosis of DVTs was also assessed.
This was achieved by screening the in-patient population at a district TB hospital. The participants received up to four routine duplex Doppler compression ultrasound examinations of the venous system of the lower extremities on week 0, week 4, week 8 and week 14. In addition a single abdominal ultrasound was performed at week 0.
Results The incidence of DVTs in this TB population was 15.3%. A median of day 10 from commencing TB treatment was identified as the most common day to develop a DVT. The popliteal vein was the most frequent position for a DVT.
Several statistically significant factors were identified, including a decreased ambulatory status, TB regimen and the use of anticoagulants. Only 52% of the DVTs were clinically symptomatic. The clinical evaluation for a DVT diagnosis in this study population had a sensitivity of 52.4% and a specificity of 65.3%. The positive predictive value (PPV) was 21.7%.
Of the abdominal ultrasound reports there were 75.5% (281) abnormal reports, 22.5% (n = 90) normal reports and 4.5% (n = 18) with no report.
Conclusion This body of work has shown how an effective ultrasound service can be provided at a district level TB hospital successfully administered by a trained ultrasonographer. This also facilitated a screening service to diagnose both symptomatic and asymptomatic deep vein thromboses in newly diagnosed tuberculosis patients. This study
confirmed a higher rate of DVT in newly diagnosed TB patients than has been previously seen. It also provided detail on additional risk factors. The study illustrates the poor performance of clinical signs and symptoms as a trigger for further investigation for the confirmation of a DVT. Given the frequency and impact of the embolic complications of DVT, this study provides a strong justification for further research into routine serial ultrasonic screening and/or prophylactic antithrombolytics in newly diagnosed TB patients. As well as the DVT ultrasound scans there was the ancillary service offered by the research sonographers. This included an abdominal scan that detected abdominal pathology in 75% of the scans performed. An ultrasound scan is not pathognomonic but it does provide significant insight into the extent of some of the abdominal pathologies seen in TB patients. The information provided from this study gives a good indication of the problem that DVTs present in this population and the complexities of the disease TB. It is hoped that the results from this study will better equip the medical team in the non-tertiary situation to be vigilant for the presence of a DVT and educate them on the usefulness of the ultrasound scan.
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Development of a normative model for cultural tourism on the Cape FlatsIsmail, Reedwaan January 2008 (has links)
THESIS SUBMITTED
IN FULFILMENT OF THE REQUIREMENTS
FOR THE DEGREE
DOCTOR TECHNOLOGIAE ( D Tech )
(TRAVEL AND TOURISM MANAGEMENT)
IN THE FACULTY OF BUSINESS
AT THE CAPE PENINSULA UNIVERSITY OF TECHNOLOGY, 2008 / This study is aimed at developing and proposing a normative model for cultural
tourism, which should be implemented on the Cape Flats. Normative criteria for
cultural tourism were identified through a literature search, followed by an empirical
study.
Responses to various questions and statements were statistically analysed,
interpreted and presented.
Tourism stakeholders such as tour operators, travel agents, accommodation
establishments and cultural tourism suppliers, including the community of the Cape
Flats, can benefit from implementation of the normative model for cultural tourism.
This study traces the roots of philosophy in the social sciences, provides a
philosophical basis for cultural tourism, followed by a discussion of relevant national,
provincial and local legislative frameworks for cultural tourism on the Cape Flats.
In addition to the above, a comparative conceptual analysis of cultural tourism in The
Gambia is made in order to gain a better understanding of successes and challenges
that face destinations, which intend to offer cultural tourism as a tourism product.
Developing a normative model for cultural tourism on the Cape Flats should seek to
invite active participation from the community from inception phase until
implementation.
The research identifies and explains elements of model theory, discusses models that
are applicable to the research area, and presents an adapted normative, input-output
systems model with a feedback mechanism. The normative model proposes an
implementation mechanism against various external and internal environmental
factors as means to ensure sustainability of cultural offerings on the Cape Flats.
The normative model proposes an approach that will facilitate employment in the
tourism sector on the Cape Flats, as well as poverty alleviation initiatives as part of
corporate social responsibility undertakings by tourism stakeholders.
Variables identified in the normative model will assist tourism stakeholders, including
the Cape Flats community, to develop cultural offerings for consumption by tourists,
the cultural market and sustain cultural tourism, which should improve standards of
living for people on the Cape Flats.
The normative model for cultural tourism addresses the critical shortage of skills
amongst tourism practitioners and offers recommendations to alleviate this
shortcoming within the tourism industry.
The normative criteria, which is identified in the model, addresses the fact that
attention should given to improvement and provision of cultural tourism infrastructure
on the Cape Flats.
An objective of the normative model for cultural tourism is to facilitate the proposal of
guidelines for National, Provincial and Local government policy initiatives regarding
tourism and, in particular, cultural tourism on the Cape Flats. This model identifies
aims and objectives of the White Paper on Sustainable Tourism Development (1996),
the Cape Flats Tourism Framework (2005) and the Tourism Development Framework
for the City of Cape Town (2006).
Finally, the Cape Flats’ diverse community displays a host of unique cultural
experiences and offerings in terms of folklore, history, experiences, food, song and a
host of other activities that should be shared with tourists.
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