The aim of the master thesis is to identify and evaluate the most appropriate and effective tools to build employer brand both externally and among employees. The theoretical part is focused on a brand theory and a concept of employer branding which, based on the labor market development not only in the Czech Republic, becomes more relevant. The methodology of the thesis consists of an analysis of the relevant scientific literature and an analysis the good practice of two selected technology companies in the Czech Republic that meet defined criteria. In the practical part a questionnaire was conducted in order to explore the perception of the employer brand among the IT public. The conclusion of the thesis is devoted to summarizing the theoretical and practical knowledge into a guide that provides important insights for IT start-up companies when building an employer brand.

Pronounced seasonal adaptations in physiology and behaviour are exhibited by mammals living in polar and temperate habitats. These include the development of a winter coat, altered fat reserves, reproductive quiescence and food hoarding. Maintaining constant body temperature (Tb) during winter is energetically very costly, and so many small mammals periodically abandon homeothermy in favour of heterothermy. The two principal heterothermic strategies are daily torpor and seasonal hibernation, in which bouts of profound hypothermia range from a few hours to several days (respectively). It is now clear that hypothalamic thyroid hormone (TH) regulation, and specifically the availability of the active metabolite triiodothyronine (T3), is a critical regulator of seasonal reproductive cycles in many species including birds and mammals. The impact of this signal as a switch for seasonal changes in physiology has been highlighted by the demonstration that blockade of this pathway prevents seasonal adaption in hamsters. Peripheral TH signalling is also a principle regulator of metabolic rate in mammals. Despite these findings nothing is yet known about the involvement of central (hypothalamic) and peripheral TH cycles in the expression of torpor and hibernation. Within this thesis, the role of TH dynamics both in the brain and peripheral circulation is examined within three models of heterothermia: the Siberian (Phodopus sungorus) and European (Cricetus cricetus) hamsters, which employ daily torpor and hibernation, respectively, and the laboratory mouse (Mus Musculus) which exhibits torpor in response to metabolic stress such as food restriction. To delineate TH regulation and signalling in the context of both seasonal and acute physiological responses, the expression of genes involved in thyroid hormones conversion (e.g. Deiodinase type II (Dio2) and type III (Dio3) and transport (e.g. Monocarboxylate transporter 8, Mct8) within the ependymal layer of the ventral 3rd ventricle have been detailed across seasonal (long (LD) and short day (SD)) photoperiods, and during normothermic and hypothermic conditions. Furthermore, TH concentrations have been directly measured within the hypothalami of P. sungorus and C. cricetus, and TH responsive genes (e.g. Hairless (Hr) and Thyrotropin releasing hormone (TRH) to determine the potential impact of regional T3 signalling. As expected, Dio2 and Dio3 expression in P. sungorus exhibited a strong seasonal cycle indicative of elevated T3 production during SD (reduced Dio2 and elevated Dio3). Unexpectedly, total T3 measures from hypothalamic extracts revealed no significant alteration either seasonally or during torpor/hibernation in hamsters. However, Hr expression in the ependymal layer and TRH expression in the paraventricular nucleus (PVN) suggests low T3 concentrations during SD are localised to specific regions and does not encompass the whole hypothalamus per se. In addition, altered serum TH concentrations implicate seasonal and torpor associated dynamics that may play a role in seasonal adaptation and hypothermia. Finally, data from transgenic mice strongly implicate the melatonin-related receptor (GPR50) in leptin signalling and aberrant thermogenesis in mice.

The H+-ATPase rich (HR) cells of zebrafish larvae are a sub-type of ion-transporting cell located on the yolk sac epithelium that are responsible for Na+ uptake and H+ extrusion. Current models of HR cell ion transport mechanisms in zebrafish larvae are well established, but little is known about the involvement of the various ion transport pathways in regulating intracellular acid-base status. In the present study, a ratiometric imaging technique using the pH indicator dye BCECF was developed to monitor intracellular pH (pHi) continuously in larval zebrafish HR cells in vivo. Initial validation experiments demonstrated that HR cells subjected to respiratory acidosis (1% CO2) or metabolic alkalosis (20 mM NH4Cl) exhibited changes in BCECF 513/438 emission ratios which were consistent with the expected effects of these treatments on pHi. Subsequent experiments focussed on the involvement of the two principal apical membrane acid excretory pathways, the Na+/H+ exchanger (isoform NHE3b; zslc9a3.2) and the H+-ATPase (atpv1aa) in pHi regulation. Additionally, the role of HR cell carbonic anhydrase (“CA2-like a”) was investigated because of its presumed role in providing H+ for Na+/H+ exchange and H+-ATPase. To do so, relative HR cell pHi changes were monitored during acid-base challenges in shams and in fish experiencing morpholino gene knockdown of either NHE3b, H+-ATPase or “CA2-like a”. The temporal pattern and extent of intracellular acidification during exposure of fish to 1% CO2 and the extent of post-CO2 alkalization were altered markedly in fish experiencing knockdown of “CA2-like a”, NHE3b or H+-ATPase. Although there were slight differences among the three knockdown experiments, the typical response was a greater degree of intracellular acidification during CO2 exposure and a reduced capacity to restore pHi to baseline levels post-hypercapnia. Knockdown of “CA2-like a”, although presumed to limit H+ availability to NHE3b and H+-ATPase, yielded qualitatively similar results to knockdown of either single H+ excretory pathway. The metabolic alkalosis and subsequent acidification associated with NH4Cl exposure and its washout were largely unaffected by gene knockdown. Overall, the results suggest markedly different mechanisms of intracellular acid-base regulation in zebrafish HR cells depending on the nature of the acid-base disturbance.

The thesis on the topic of Taking Care of GE and Knowledge Transfer in Company X has examined the practice in the field of the global assignments of the company X hand in hand with a qualitative research method among the GE of X. First, theoretical proposals were introduced and analysed. Then they were connected with the results of the research and discussed and proposals were made for optimising of the care taking about the GE and for releasing the knowledge flow in X.

Popis personálních činností ve firmě Protool s.r.o., které jsou zkoumány vnitřním auditem personálch činností. Těchto 10 personálních procesů je detailně rozebráno a jsou zde navrhnuty možnosti, jak současný stav vylepšit nebo se alespoň příbližit k optimu. Na závěr jsou fakta přehledně seřazeny do tabulky a jednotlivé personální činnosti jsou ohodnoceny na bodovací škále od 1 do 5.

This thesis deals with the organisational structure of human resources. The aim is to identify the role of HR in companies, explore the transformation process, recognize the main reasons for transformation and uncover the new structure of HR. This thesis places emphasis on the HR Business Partnership model and its three main parts - HR Business Partner, Shared Services Centre and Centre of Excellence. It is based partly on secondary data and partly on structured interviews with chosen companies.

My diploma thesis is dedicated to the issue of data mining, its part of predictive analysis and then process that is used in HP for different prediction. The introductory part describes the concept of data mining, its role and benefits. To one of its tasks fall predictive analysis, where I discussed the principles of its use. Then follows framework HP, which uses one of the tasks of predictive analysis. In the practical part, I applied the use VBA to automate one part of the process of converting text to numerical data, assuming different rules. The result is a set of macros support, system sheet and the new ribbon for data transformation.

Master's Thesis is focused on personnel management in public sector. Human Resources are the basis for quality and efficient managing of public administration. Theoretical aspects of personnel management in the public sector are stated in the first part of the thesis. There are described the roles of personnel management in public administration and subsequently there are described the theoretical differences between personnel management in the public and private spheres. In the second part of the theory there are specified individual personnel activities such as job analysis, recruitment and selection of employees, employee adaptation, employment closing, employee training, employee evaluation and employee wages and benefits. Beside usual literature there are quotes from the Act No. 312/2002 Coll. of local government officials and amending certain laws. The practical part describes and analyzes the personnel activities in two districts of Prague, namely the Municipal Authority of Prague 9 and Prague 13. The aim of the thesis is to evaluate personnel management in selected urban areas, compare them to each other and suggest some improvements and recommendations for the future.

This master thesis is dealing with the topic of perception and role of HR department in a firm from the employees' perspective. The aim was to find out the satisfaction of employees with HR services. In two international companies ("A" and "B") there was conducted a survey among company team leaders (supervisors and managers), which was aiming to find out their intensity of use and satisfaction level with HR. It was discovered that respondents from company A use given HR services (recruitment, HR operations, training and development, remuneration and internal communication) more often than company B but are less satisfied. As an output of this thesis, there were given some recommendations to both companies, so that their HR team can improve its position and thus reputation of the whole personnel department in the company.

The diploma thesis deals with the concept of HR business partnerships in Czech companies. The aim of this thesis is to describe, analyze and evaluate the level of implementation of HR business partnering in selected companies. Theoretical section defines concept of product placement followed by look into its historical development. Practical section of this study presents executed research in two selected companies that have already implemented this concept. The chosen method is qualitative analysis based on interviews with company managers followed by evaluation, comparison and suggestions for improvement of the whole concept of HR business partnerships. Key words HR business