The job of a package delivery driver (PDD) is complex and demanding. These drivers must possess many skills in order to succeed in their work, including physical stamina, appropriate decision-making, positive customer interaction, and most importantly, operational safety. Companies must use significant resources, not only to provide insurance for existing drivers, but also to train new drivers to use their visual attention effectively while driving, and companies have a vested interest in ensuring that the most capable trainees are selected for jobs. Currently, subjective assessments of supervisors or managers are typically used to make these determinations. While these are valuable methods for assessing drivers, an objective measure of how well the driver is using his/her visual attention would both assist evaluators in making judgments, as well as make those judgments more accurate. The purpose of the study described herein was to 1) conduct a task analysis of the driving component of the PDD job responsibilities, and 2) create and test an objective measure that a package delivery company could use to evaluate the performance of its drivers. A detailed task analysis based on numerous observations of drivers in their normal work routines was conducted for this research in order to understand these complex tasks. A framework was created for understanding this system of tasks, which was then used to organize all tasks that drivers were observed to perform into more general, goal-oriented activities. Using this task analysis, incidents were identified that were observed while drivers were behind the wheel. This information demonstrated that breakdowns were occurring within the tasks drivers were performing and that improved methods of training and evaluations may be needed as a result. A construct of visual behavior called Head Down Time (HTD) was then created and tested. An individual HDT is defined as the sum of time of all eye gazes away from the primary display (i.e. windshield) between two distinct eye gazes at the primary display while the vehicle is in motion. HDT was evaluated for its ability to differentiate levels of experience between drivers, its relationship to types of route on which drivers delivered, and its relationship to the driving-related incidents that were observed. HDTs were shown to be differed significantly between drivers of low and high experience, with experienced drivers displaying shorter durations of HDT when compared to inexperienced drivers. HDTs also differed in duration when analyzed by the type of route upon which drivers operated. Commercial and urban routes, while not significantly different with respect to HDT, were shown to have increased HDT durations when compared to rural routes and, in turn, residential routes were found to have significantly longer HDTs than did rural routes and may have significantly shorter durations compared to commercial and urban. Finally, HDTs that were associated with observed driving incidents in terms of chronological proximity were shown to be of significantly longer duration than were HDTs that were not associated with incidents. All tests were conducted using appropriate statistical measures, including t-tests at a level of α = 0.05 for each dataset. Applications of this research include: 1) improvement of PDD training and evaluation methods through use of a detailed task analysis, 2) improvement in how package delivery companies define incidents and train PDD toward the prevention of incidents based on task analysis and observations as to incident frequency, and 3) the further development of HDT as a possible objective measure to supplement the training and evaluation of PDD. / Master of Science

This study was designed to test the hypothesis that 60 days continuous head down bed rest (HDBR), an Earth-based analogue of the effects of space flight, would elevate factors that increase vasoconstriction and would increase markers of vascular inflammation. The study incorporated countermeasures consisting of treadmill running within lower-body negative pressure and resistive "flywheel" exercise (exercise countermeasure, EX) or an increased protein intake of 0. 6 g/kg body weight/day (dietary countermeasures, DIET) to determine whether these interventions might prevent the vasoconstrictor and inflammatory responses when compared to a control (CON) group. Markers of vascular health measured in the study include the vasoactive molecules angiotensin II (Ang II), endothelin-1 (ET-1), and nitric oxide metabolites (NO_met); and markers of inflammation including C-reactive protein (CRP), and the adhesion molecules E-selectin (E-sel), intracellular adhesion molecule-1 (ICAM), and vascular cell adhesion molecule-1 (VCAM). Twenty four women were housed at the MEDES clinic in Toulouse, France, as part of a large international study (Women International Space Simulation for Exploration, WISE) in which various experimental protocols and countermeasures were integrated into a single experimental design completed during two campaigns. Each 100 day campaign included 20 days of pre-testing (pre-HDBR), 60 days of bed rest (HDBR), and 20 days of post-testing (post-HDBR). The experimental countermeasures were applied only during the 60-day HDBR period. Following 60 days of HDBR, many changes occurred in the concentrations of the measured molecules. Specifically, the concentration of Ang II significantly increased in the CON and DIET groups (52. 9%, p = 0. 014; and 124. 4%, p <0. 0001 respectively), but not in the EX group. Also, NO_met decreased in all groups, with reductions in the EX and DIET groups (p = 0. 013, and p = 0. 056 respectively). Markers used to assess vascular inflammation increased following the HDBR. The increase in CRP in the CON and DIET groups and the decrease in the EX group from pre- to post-HDBR were not significant; however, the directional changes resulted in an interaction between group and HDBR (p = 0. 052). The adhesion molecule E-sel was significantly increased in the DIET group (p = 0. 003), and VCAM was significantly increased in the CON group (p = 0. 016) with a smaller increase in the DIET group (p = 0. 08). No changes in adhesion molecules were observed in the EX group. This study demonstrated that 60 days of HDBR by young, healthy, women caused changes in several different molecules that are beginning to emerge as risk factors for the development of cardiovascular diseases. Further, it was observed that regular, vigorous exercise during HDBR prevented these changes. These results suggest that future studies of this kind should directly monitor the effects of simulated space flight on vascular health in men and women to obtain a greater understanding of the adaptations that might occur during long term space exploration missions. HDBR can be considered an extreme model of physical inactivity and could be used to provide insight into mechanisms of disease processes associated with the sedentary lifestyle that is prevalent in Western society.

This study was designed to test the hypothesis that 60 days continuous head down bed rest (HDBR), an Earth-based analogue of the effects of space flight, would elevate factors that increase vasoconstriction and would increase markers of vascular inflammation. The study incorporated countermeasures consisting of treadmill running within lower-body negative pressure and resistive "flywheel" exercise (exercise countermeasure, EX) or an increased protein intake of 0. 6 g/kg body weight/day (dietary countermeasures, DIET) to determine whether these interventions might prevent the vasoconstrictor and inflammatory responses when compared to a control (CON) group. Markers of vascular health measured in the study include the vasoactive molecules angiotensin II (Ang II), endothelin-1 (ET-1), and nitric oxide metabolites (NO_met); and markers of inflammation including C-reactive protein (CRP), and the adhesion molecules E-selectin (E-sel), intracellular adhesion molecule-1 (ICAM), and vascular cell adhesion molecule-1 (VCAM). Twenty four women were housed at the MEDES clinic in Toulouse, France, as part of a large international study (Women International Space Simulation for Exploration, WISE) in which various experimental protocols and countermeasures were integrated into a single experimental design completed during two campaigns. Each 100 day campaign included 20 days of pre-testing (pre-HDBR), 60 days of bed rest (HDBR), and 20 days of post-testing (post-HDBR). The experimental countermeasures were applied only during the 60-day HDBR period. Following 60 days of HDBR, many changes occurred in the concentrations of the measured molecules. Specifically, the concentration of Ang II significantly increased in the CON and DIET groups (52. 9%, p = 0. 014; and 124. 4%, p <0. 0001 respectively), but not in the EX group. Also, NO_met decreased in all groups, with reductions in the EX and DIET groups (p = 0. 013, and p = 0. 056 respectively). Markers used to assess vascular inflammation increased following the HDBR. The increase in CRP in the CON and DIET groups and the decrease in the EX group from pre- to post-HDBR were not significant; however, the directional changes resulted in an interaction between group and HDBR (p = 0. 052). The adhesion molecule E-sel was significantly increased in the DIET group (p = 0. 003), and VCAM was significantly increased in the CON group (p = 0. 016) with a smaller increase in the DIET group (p = 0. 08). No changes in adhesion molecules were observed in the EX group. This study demonstrated that 60 days of HDBR by young, healthy, women caused changes in several different molecules that are beginning to emerge as risk factors for the development of cardiovascular diseases. Further, it was observed that regular, vigorous exercise during HDBR prevented these changes. These results suggest that future studies of this kind should directly monitor the effects of simulated space flight on vascular health in men and women to obtain a greater understanding of the adaptations that might occur during long term space exploration missions. HDBR can be considered an extreme model of physical inactivity and could be used to provide insight into mechanisms of disease processes associated with the sedentary lifestyle that is prevalent in Western society.

Peak oxygen uptake (VO2PEAK) in endurance exercise trained (ET =8) subjects (VO2PEAK = 61.7 1.6 ml 02.kg.min-1) was compared to the V02 PEAK of untrained (UT = 8) subjects (V02 PEAK = 38.4 1.7 ml 02 -kg.min1) after four hours of -6* head-down rest (HDR).Although both groups showed a reduction in blood volume (BV) following HDR, this decrement was greater for ET subjects (delta BV = -3.23 0.46 mi/kg; P <0.05). The ET subjects had a greater decrease in VO2=(delta 02E -5.58 1.05 ml 02-kg.min-1; P <0.05) than their UT peers (VO2PEAK = -2.44 0.79 ml02-kg.min-1). These data suggest that the greater reductions in VO2PE, observed for the ET group were associated with a greater BV loss resulting from 4 h of HDR prior to exercise.

<p>Arbetsbelastningen för föraren i en engreppsskördare är stor. Vid aptering måste föraren fokusera om blicken för att läsa av information från en Head-Down Display (HDD) samtidigt som föraren måste ha kontroll på kranspetsen vilket bidrar till arbetsbelastningen.</p><p>Syftet med projektet var att undersöka om arbetsbelastningen i engreppsskördare reducerades med Head-Up Display (HUD) under aptering. Först testades fyra HUD-gränssnitt i en simulator, därefter omarbetades gränssnitten innan de slutligen testades i en engreppsskördare i fält. En HUD-demonstrator utvecklades för detta ändamål.</p><p>Resultatet visade att arbetsbelastningen samt apteringstiderna minskade i simulatortestet med HUD jämfört med HDD. I fältstudien förblev arbetsbelastningen oförändrad men apteringstiderna minskade.</p><p>Att arbetsbelastningen minskade med HUD jämfört med HDD kan bero på att HUD är bättre än HDD och/eller att konceptens gränssnitt är effektivare att arbeta med än Valmet Maxi gränssnittet.</p><p>En HUD-demonstrator som fungerar under ljusstarka förhållanden och som tål påfrestningarna i en skördare borde utvecklas för vidare tester.</p>

Arbetsbelastningen för föraren i en engreppsskördare är stor. Vid aptering måste föraren fokusera om blicken för att läsa av information från en Head-Down Display (HDD) samtidigt som föraren måste ha kontroll på kranspetsen vilket bidrar till arbetsbelastningen. Syftet med projektet var att undersöka om arbetsbelastningen i engreppsskördare reducerades med Head-Up Display (HUD) under aptering. Först testades fyra HUD-gränssnitt i en simulator, därefter omarbetades gränssnitten innan de slutligen testades i en engreppsskördare i fält. En HUD-demonstrator utvecklades för detta ändamål. Resultatet visade att arbetsbelastningen samt apteringstiderna minskade i simulatortestet med HUD jämfört med HDD. I fältstudien förblev arbetsbelastningen oförändrad men apteringstiderna minskade. Att arbetsbelastningen minskade med HUD jämfört med HDD kan bero på att HUD är bättre än HDD och/eller att konceptens gränssnitt är effektivare att arbeta med än Valmet Maxi gränssnittet. En HUD-demonstrator som fungerar under ljusstarka förhållanden och som tål påfrestningarna i en skördare borde utvecklas för vidare tester.

Diss. (sammanfattning) Stockholm : Karolinska institutet, 2005. / Härtill 4 uppsatser.

Whereas the effects of a long-term activity of head-down tilt (HDT) in the angle between 3ř and 12ř were examined in details in cosmic medicine as the model of a state of weightlessness, literature concerning effect of HDT on cardiovascular control in the angle over 30ř is scarce. The aim of the thesis is to examine acute reaction of systolic, diastolic, mean arterial blood pressure and heart rate during three minutes of 30ř, 50ř and 70ř HDT, realized on a tilt (inversion) table with fixed legs. For the combination of HDT and head-up tilt (HUT), the following protocol was chosen: 5 minutes lying in a horizontal position (HOR), 3 minutes of 70ř HUT, 3 minutes of 30ř HDT, 3 minutes of HOR, 3 minutes of 50ř HDT, 3 minutes HOR, 3 minutes of 70ř HDT, 3 minutes HOR and 3 minutes of 70ř HUT. A non-invasive continuous Peňáz method, using Finapres Ohmeda, was used to monitor beat-by-beat blood pressure and heart rate. Blood pressure was also measured by sphygmomanometer each minute for calibration. In the angle of 30ř HDT, there was a significant decline of heart frequency (p < 0,01). During the 50ř HDT, there was a significant rise of systolic blood pressure in the third minute, of diastolic and mean arterial pressure each minute and the heart rate dropped significantly (all p < 0.05). In the 70ř HDT,...

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The human body has substantial kinetic and kinematic degrees-of-freedoms, so redundant solutions are available for the central nervous system (CNS) to perform a repetitive task. Due to these redundancies, inherent variations exist in human movement, called motor variability (MV). Current evidence suggests that MV can be beneficial, and that there is an inverse association between MV and risk of injury. To better understand how the CNS manipulates MV to reduce injury risks, we investigated the effects of individual differences, task-relevant aspects, and psychological factors as modifiers of MV. Earlier work found that experienced workers adapted more stable movements than novices in repetitive lifting tasks. To expand on this, we quantified how MV differs between experienced workers and novices in different lifting conditions (i.e., lifting asymmetry and fatigue). Three different measures (cycle-to-cycle SD, sample entropy, and the goal equivalent manifold) were used to quantify MV. In a symmetric lifting task, experienced workers had more constrained movement than novices, and experienced workers exhibited more consistent behavior in the asymmetric condition. Novices constrained their movements, and could not maintain the same level of variability in the asymmetric condition. We concluded that experienced workers adapt stable or flexible strategies depending on task difficulty. In a prolonged lifting task, both groups increased their MV to adapt to fatigue; they particularly increased variability in a direction that had no effects on their main task goal. Developing fatigue also makes it difficult for individuals maintain the main goal. Based on these results, we conclude that increasing variability is an adaptive strategy in response to fatigue. We also assessed variability in gait parameters to compare gait adaptability using a head-worn display (HWD) compared with head-down displays for visual information presentation. An effective strategy we observed for performing a cognitive task successfully during walking was to increase gait variability in the goal direction. In addition, we found that head-up walking had smaller effects on MV, suggesting that HWDs are a promising technology to reduce adverse events during gait (e.g., falls). In summary, these results suggest that MV can be a useful indicator for evaluating some occupational injury risks. / Ph. D.