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Investigating the Misrepresentation of Statistical Significance in Empirical ArticlesLybrand, Blythe, Blackhart, Ginette, Parish, Amanda, Lowe, Hannah 01 May 2021 (has links)
In an attempt to preserve research integrity, the aim of this study is to examine how often statistical results are being misrepresented in empirical studies by using terms such as “marginally significant,” “approached significance,” or “trend toward significance” when interpreting findings. The use of these terms gives ambiguous significance to results that are in fact nonsignificant, which threatens future research by contributing to issues such as the replication crisis. For this study, data were coded from 437 empirical articles published online in The Journal of Personality and Social Psychology (JPSP) over a 4-year period between 2017 and 2020. According to our findings, although misrepresentation of statistical results are prevalent within JPSP articles, rates decreased significantly over the four-year time period examined. Additionally, as the number of studies published in JPSP increased each year during the four-year period examined, there may be a potential rise in representatively sound studies and decrease of misrepresentation within this discipline.
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Caracterizações de subvariedades marginalmente aprisionadas em formas espaciais / Characterizations of marginally trapped submanifolds in space-formsCouto, Ivo Terek 29 March 2018 (has links)
Neste trabalho, estudamos as subvariedades das formas espaciais pseudo-Riemannianas M^n_v(c) com vetor curvatura média de tipo luz, chamadas marginalmente aprisionadas, explorando as relações desta condição (motivada pela Física) com várias outras hipóteses de caráter geométrico, como lambda-isotropia, presença de nulidade relativa e invariância por um certo grupo de transformações de Lorentz. Em particular, apresentamos vários resultados de classificação e rigidez de superfícies marginalmente aprisionadas nos espaços de Lorentz-Minkowski L^4, de Sitter S^4_1 e anti-de Sitter H^4_1 nestes contextos, adaptando e generalizando resultados de alguns artigos. / In this work, we study the submanifolds of pseudo-Riemannian space forms M^n_v(c) with lightlike mean curvature vector, called marginally trapped, exploring the relations of this condition (motivated by Physics) with several other assumptions of geometric character, such as \\lambda-isotropy, presence of relative nullity and invariance by a certain group of Lorentz transformations. In particular, we prove several ridigity and classification results for marginally trapped surfaces in Lorentz-Minkowski space L^4, de Sitter space S^4_1 and anti-de Sitter space H^4_1 in these settings, adapting and generalizing results from several papers.
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Caracterizações de subvariedades marginalmente aprisionadas em formas espaciais / Characterizations of marginally trapped submanifolds in space-formsIvo Terek Couto 29 March 2018 (has links)
Neste trabalho, estudamos as subvariedades das formas espaciais pseudo-Riemannianas M^n_v(c) com vetor curvatura média de tipo luz, chamadas marginalmente aprisionadas, explorando as relações desta condição (motivada pela Física) com várias outras hipóteses de caráter geométrico, como lambda-isotropia, presença de nulidade relativa e invariância por um certo grupo de transformações de Lorentz. Em particular, apresentamos vários resultados de classificação e rigidez de superfícies marginalmente aprisionadas nos espaços de Lorentz-Minkowski L^4, de Sitter S^4_1 e anti-de Sitter H^4_1 nestes contextos, adaptando e generalizando resultados de alguns artigos. / In this work, we study the submanifolds of pseudo-Riemannian space forms M^n_v(c) with lightlike mean curvature vector, called marginally trapped, exploring the relations of this condition (motivated by Physics) with several other assumptions of geometric character, such as \\lambda-isotropy, presence of relative nullity and invariance by a certain group of Lorentz transformations. In particular, we prove several ridigity and classification results for marginally trapped surfaces in Lorentz-Minkowski space L^4, de Sitter space S^4_1 and anti-de Sitter space H^4_1 in these settings, adapting and generalizing results from several papers.
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Top of the Line Corrosion in CO<sub>2</sub>/H<sub>2</sub>S EnvironmentsYaakob, Najmiddin 25 August 2015 (has links)
No description available.
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Intra- and intermolecular interactions in proteins : Studies of marginally hydrophobic transmembrane alpha-helices and protein-protein interactions.Hedin, Linnea E January 2010 (has links)
Most of the processes in a living cell are carried out by proteins. Depending on the needs of the cell, different proteins will interact and form the molecular machines demanded for the moment. A subset of proteins called integral membrane proteins are responsible for the interchange of matter and information across the biological membrane, the lipid bilayer enveloping and defining the cell. Most of these proteins are co-translationally integrated into the membrane by the Sec translocation machinery. This thesis addresses two questions that have emerged during the last decade. The first concerns membrane proteins: a number of α-helices have been observed to span the membrane in the obtained three-dimensional structures even though these helices are predicted not to be hydrophobic enough to be recognized by the translocon for integration. We show for a number of these marginally hydrophobic protein segments that they indeed do not insert well outside of their native context, but that their local sequence context can improve the level of integration mediated by the translocon. We also find that many of these helices are overlapped by more hydrophobic segments. We propose, supported by experimental results, that the latter are initially integrated into the membrane, followed by post-translational structural rearrangements. Finally, we investigate whether the integration of the marginally hydrophobic TMHs of the lactose permease of Escherichia coli is facilitated by the formation of hairpin structures. However our combined efforts of computational simulations and experimental investigations find no evidence for this. The second question addressed in this thesis is that of the interpretation of the large datasets on which proteins that interact with each other in a cell. We have analyzed the results from several large-scale investigations concerning protein interactions in yeast and draw conclusions regarding the biases, strengths and weaknesses of these datasets and the methods used to obtain them. / At the time of the doctoral defense the following publications were not published and had a status as follows: Paper 2: In press; Paper 4 Manuscript.
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Marginally hydrophobic transmembrane α-helices shaping membrane protein foldingde Marothy, Tuuli Minttu Virkki January 2014 (has links)
Most membrane proteins are inserted into the membrane co-translationally utilizing the translocon, which allows a sufficiently long and hydrophobic stretch of amino acids to partition into the membrane. However, X-ray structures of membrane proteins have revealed that some transmembrane helices (TMHs) are surprisingly hydrophilic. These marginally hydrophobic transmembrane helices (mTMH) are not recognized as TMHs by the translocon in the absence of local sequence context. We have studied three native mTMHs, which were previously shown to depend on a subsequent TMH for membrane insertion. Their recognition was not due to specific interactions. Instead, the presence of basic amino acids in their cytoplasmic loop allowed membrane insertion of one of them. In the other two, basic residues are not sufficient unless followed by another, hydrophobic TMH. Post-insertional repositioning are another way to bring hydrophilic residues into the membrane. We show how four long TMHs with hydrophilic residues seen in X-ray structures, are initially inserted as much shorter membrane-embedded segments. Tilting is thus induced after membrane-insertion, probably through tertiary packing interactions within the protein. Aquaporin 1 illustrates how a mTMH can shape membrane protein folding and how repositioning can be important in post-insertional folding. It initially adopts a four-helical intermediate, where mTMH2 and TMH4 are not inserted into the membrane. Consequently, TMH3 is inserted in an inverted orientation. The final conformation with six TMHs is formed by TMH2 and 4 entering the membrane and TMH3 rotating 180°. Based on experimental and computational results, we propose a mechanism for the initial step in the folding of AQP1: A shift of TMH3 out from membrane core allows the preceding regions to enter the membrane, which provides flexibility for TMH3 to re-insert in its correct orientation. / <p>At the time of the doctoral defense, the following paper was unpublished and had a status as follows: Paper 2: Manuscript.</p>
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Kvazilokální horizonty / Quasilocal horizonsKlozová, Eliška January 2015 (has links)
In this thesis we discuss drawbacks of the event horizon which is defined glo- bally in spacetime and we introduce a quasilocal definition of black hole boundary foliated by marginally trapped surfaces on which the expansion of the outer null normal congruence becomes zero. List of different types of quasilocal horizons follows, i.e. apparent horizon, trapping horizon and isolated and dynamical hori- zon. Subsequently we calculate and analyse quasilocal horizons in two dynamical spacetimes which are used as inhomogeneous cosmological models. We discover future and past horizon in spherically symmetric Lemaître spacetime and we come to conclusion that both are null and have locally the same geometry as the ho- rizons in the LTB spacetime. Then we study Szekeres-Szafron spacetime with no symmetries, particularly its subfamily with β,z ̸= 0, and we derive the equation of the horizon. However, because of the lack of symmetries the spacetime is not adapted to double-null foliation, therefore we were unsuccessful in our attempts to estimate the equation's solution. Only in a special case when the function Φ does not depend on the coordinate z we found a condition on the existence of the horizon, that is Φ,t Φ > 0. 1
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累積滿意度邊際微調模型之研究—消費者失驗之觀點 / A Study on Cumulative Satisfaction-Based Transaction-Specific Satisfaction Marginally Adjusting Model: Consumers' Disconfirmation Perspective魏聖忠, Wei, Sheng-Chung Unknown Date (has links)
本研究提出一個四階段的消費者重購承諾心理評價程序模式,認為消費者將依據知覺品質和期望品質的比較形成品質失驗,然後藉由內在的價值函數將品質失驗轉換成為同樣是失驗觀點的個別交易滿意度(滿意度失驗)。在形成個別交易滿意度之後,消費者將依循累積滿意度基礎的個別交易滿意度邊際微調模型來形成當期的累積滿意度,並且依據當期的累積滿意度和當期的忠誠門檻值比較的結果,進而產生品牌忠誠或品牌轉換的行為意圖。
整體而言,失驗觀點的個別交易滿意度(滿意度失驗)和品質失驗之間的關係大致服膺期望理論價值函數的特性。此外,本研究提出的累積滿意度基礎的個別交易滿意度邊際微調模型也獲得支持,並進一步確定累積滿意度的調整過程主要是採行性線的調整模式。最後,本研究提出的累積滿意度忠誠門檻模型亦獲得實證證據的充分支持。因此,一旦當期的累積滿意度決定之後,消費者將以他心目中對競爭品牌的累積滿意度做為比較的基礎、當作忠誠門檻值,進行焦點品牌累積滿意度和競爭品牌累積滿意度的比較,並且依據比較的結果形成品牌忠誠或品牌轉換的行為意圖。 / This study proposes a four-stage model about the process of consumers’ repurchase commitment. The model postulates that consumers would result in quality disconfirmation based on the result of comparison between perceived quality and expected quality, then transform it through intrinsic value function into transaction-specific satisfaction which is defined as satisfaction disconfirmation. Once transaction-specific satisfaction is formed, consumers would result in current cumulative satisfaction according to cumulative satisfaction-based transaction-specific satisfaction marginally adjusting model that depicts current cumulative satisfaction as a function of previous cumulative satisfaction and current transaction-specific satisfaction. And finally, according to loyal threshold model of cumulative satisfaction, intention to repurchase or switch buying would be formed based on the relative magnitude between cumulative satisfaction and loyal threshold which is defined as cumulative satisfaction towards a main competing brand.
Overall speaking, the relation function between quality disconfirmation and transaction-specific satisfaction exhibits most traits of value function depicted in the prospect theory. Furthermore, the cumulative satisfaction-based transaction-specific satisfaction marginally adjusting model proposed by this study was supported by experimental data, and the result shows that the adjusting process of cumulative satisfaction complies mainly with linear adjusting model. And finally, the loyal threshold model of cumulative satisfaction was fully supported by experimental data, and the result implies that consumers would take the cumulative satisfaction towards a main competing brand as the comparing basis, i.e., loyal threshold, and then compare cumulative satisfaction towards a focal brand with this comparing basis to decide whether to repurchase the products of the focal brand or instead switching to buy the goods of the competing brand.
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Exploring narratives of coping and resilience with socio-economic and emotional challenges in a group of Zimbabwean migrants: a qualitative studySigamoney, Rosalind Florence 09 1900 (has links)
Bibliography: pages 227-250 / The research intended to explore the narratives of coping and resilience relating to the socio economic and emotional difficulties of a group of Zimbabwean migrants residing in
Johannesburg. Through a technique of social constructionism and dialogue between the
researcher and the six (6) participants, the co-construction in accordance to subject matters
was used, supported by way of a qualitative research strategy and the case study method. The
exploration of the themes was based on the participants’ narratives. Thereafter, the thematic
analysis methodology was undertaken to analyse the data and connect it to supportive
literature. The sample generated a full and rich account of the participants’ experiences and
this yielded awareness of the common themes, such as the challenges and coping in trying
times of migration, as well as an in-depth interpretation of their resilience. A qualitative
research method was employed. Purposeful sampling was used and semi-structured in-depth
personal interviews were conducted with each of the six (6) participants. Three (3) male and
three (3) female Zimbabwean migrants were chosen. The case study included a description of
Zimbabwean migrants’ coping and resilience with socio-economic and emotional challenges.
It is anticipated that the results from this study will influence the progress of a unique review
and support programme for the migrants who have endured socio-economic and emotional
challenges. The results disclosed the reasons for migrating to South Africa, the challenges in
the country of resettlement, socio-economic and emotional challenges, and the strategies used
to cope and become resilient. Additionally, the analysis concluded that the participants in the
study experienced similar narratives. The female participants left their families to seek
greener pastures economically, but emotionally it affected their well-being. The Zimbabwean
migrants coped with resilience utilising social networks, religion, self-regulation and mobile
technology. / Psychology / D. Phil. (Psychology)
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