No abstract available. / Thesis (M.Dev.Studies)-University of Natal, Durban, 2003.

MA / African horsesickness is a disease endemic in Sub Saharan Africa affecting horses, a non-native species, which are extremely susceptible to this disease. Both the ‘dunkop’ form (with its dramatic high fever, laboured breathing, frothy nasal discharge and sudden death) and the ‘dikkop’ form (with its swollen head and eyes and bleeding in the membranes of the mouth and eyes) have been visited upon equine populations and their human owners in successive epidemics through the earliest colonial settlement until recent times. This thesis traces the development of veterinary science in South Africa and the effect it had on the changing ideas surrounding African horsesickness. It explores not only the veterinary progress in the country but also the impact of the progress on African horsesickness as other diseases received attention. The discussion traces the disease from one of the major epidemics ever encountered in the country, in the mid nineteenth century, to the beginning of the development of veterinary services in South Africa when little was known about African horsesickness. It illustrates the implications of a country's struggle with animal disease, the reasons for a lack of knowledge and the ramifications of the Onderstepoort Veterinary Institute’s interventions. This thesis shows that African horsesickness not only had an impact on the veterinary developments of the country but was also indirectly involved in the South African War, 1899-1902. It demonstrates the impact of disease during wartime while illustrating the importance of horses during such difficult times. Thus, this thesis draws on works on animal diseases and on social history to explore not only the effect African horsesickness had historically on equines, but the effects it had more broadly on southern African society. This study is intended to bring insight into the social history of the disease itself: how it was experienced by livestock owners and also how settler and indigenous efforts were turned towards combating this dramatic disease.

Medicine unavailability, also known as stock-outs is a global problem. South Africa is not exempt from this problem which impacts negatively on the way in which healthcare services are rendered, more especially in the public sector. Communities are complaining about the unavailability of medicines at public health facilities particularly in primary health care clinics. In an effort to address this problem, the Minister of Health has declared medicine availability as one of the six priorities of the Department of Health. The aim of this study was to explore and describe the experiences and perceptions of healthcare professionals practicing at primary healthcare clinics in a peri-urban area of the Eastern Cape regarding the unavailability of medicines. Understanding the experiences and perceptions was expected to assist in addressing the problem at hand and help management in developing ways to address the problem and support the employees. Semi-structured interviews were conducted with healthcare professionals working at primary health care clinics in and around Mdantsane Township in the Eastern Cape. The main findings of the study can be divided into the following topics: perceived causes of medicine stock-outs, the implications of stock shortages, actions taken in the case of stock-outs and the role to play by in mitigating the impact of stock shortages. The limitations of the study include the research sample which was not truly representative of all healthcare professionals working at Mdantsane sub-district primary healthcare clinics. The study recommends various strategies that management should follow to assist in addressing medicine shortages. The researcher recommends further research to describe the experiences of healthcare professional regarding medicine unavailability.

This study aimed to investigate the role of the interpreter in medical communication in the Eastern Cape. This role was found to be a complex and varied one. Interpreters do not only change the words of one language into equivalent words in the other language, but act as advisers, explainers, cultural mediators, supervisors and advocates of the patient. In order to fulfil these functions, they communicate independently within the medical consultation and do not merely interpret what has been said by each participant. Rather, they tailor the message to the participants and the situation by adding to the message, omitting parts of it and changing it where necessary. This does not happen in an arbitrary fashion, but is subject to influence from a number of non-linguistic and linguistic contextual factors. These factors are discussed in this study and included in a suggested model of the interpreted medical consultation, which differs from other models of interpreting which were found to be more adequate for the-situation of conference interpreting than for community interpreting, of which medical interpreting is an example. Data was collected from interviews with interpreters and patients apd from interviews and questionnaires given to medical professionals. The results suggest that using trained medical interpreters in the interpreted medical consultation may solve some of the problems that arise and medical professienals should be encouraged to, learn the languages of their patients to alleviate some of the misunderstanding which occurs. The study also raises questions about the way in which we view interpreting and shows that community interpreting does not always observe the ideals envisaged by theories of interpreting.

This dissertation explores discourses about culture and illness in the talk of mental health professionals and indigenous healers. It represents an attempt to situate the issue of indigenous healing in South Africa within a particular strand of critical discourse analytic research. In the context of current deliberations on the value, or otherwise, of indigenous healing in a changing health and specifically mental health system, the talk of both mental health practitioners and indigenous healers as they conceptualise “disorder”, and discuss possibilities for collaboration, is chosen as a specific focus for this study. Disputes over what constitutes “disorder” both within mental health, and between mental health and indigenous healing are an important site in which the negotiation of power relations between mental health professionals and indigenous healers is played out. The results of this study suggest that despite the construction of cogent commendations for the inclusion of indigenous healing in mental health, it remains largely marginalised within talk about mental health practice. While this study reproduces to some extent the marginalisation of indigenous healing discourse, it also examines some of the discursive practices and methodological difficulties implicated in its marginalisation. However, in the context of “cultural pride strategies” associated with talk about an African Renaissance, indigenous healing may also function as a site of assertion of African power and resistance in its construction as an essentially African enterprise. At the same time, it may achieve disciplinary effects consonant with cultural pride strategies, in constructing afflictions in terms of neglect of, or disloyalty to cultural tradition. These results are discussed in terms of the methodological difficulties associated with interviewing and discourse analysis of translated texts, which contributes to difficulties with articulating indigenous healing discourse in a way that challenges the dominant psychiatric discourses implicated in its marginalisation within mental health. It concludes with recommendations for future research which addresses indigenous healing discourse in its own terms, and examines its operation as a disciplinary apparatus in South African society.

Thesis (DTech (Electrical engineering))--Cape Peninsula University of Technology, Cape Town, 2007 / Telemedicine has been identified as a tool to distnllUte medical expertise to medically underserved rural community. However, due to the underdeveloped or non-existent telecommunication infrastructure, which is needed as the platform for telemedicine, the full benefits of telemedicine are yet to be realized in most parts of South Africa and Africa as a whole. This study aims to explore ways on how to provide lP-based lCI system that can be used as a communication platform for telemedicine in rural areas. In order to emulate the onsite face-to-face consultation experience, the rural telemedicine system must be able to provide quality video transmission. Quality video is also important in order for the physician at the distant end to be able to make correct diagnosis. Hence the main focus of this study is on ways ofproviding quality video over lP-based multiservice network. A conceptual model of a rural area network that can be used for rural telemedicine has been deVeloped, and different access technologies that can be used for rural areas are presented. Techniques for compesating IP best effort datagram delivery are provided. Factors that can affect the quality of video transmission on an lP-based packet network are identified, and a holistic approach to mitigate them is proposed. That includes adopting coding techniques that will provide coding efficiency, high quality video that is consistent at high and low bit rates, resilience to transmission errors, scalability, and network friendliness, which will result in perceived quality improvement, highcompression efficiency, and possibility of transportation over different networks. Secondly, it also includes mechanisms to compensate for packet networks idiosyncrasy, especially JP best-effort debilities, in order to meet the latency and jitter requirements of real-time video traffic. For video coding, H.264 is proposed as it meets most of the encoding requirements listed above, and for prioritising and protecting.video traffic from JP network's best-effort debilities a combination of differential services (DiflServ) and multi-protocol label switching (MPLS) have been adopted, where DiflServ is used for traffic classification and MPLS is used for traffic engineering and fast-rerouting in the event of route failure. To verify and validate the proposed solutions, modelling and simulation has been used, where the Network Simulator (NS-2.93) has been used to simulate network functions, and PSNR, VQM score and double stimulus impairment scale (DSIS) have been used for evaluating video quality.

In medical anthropology there has been a tendency to dichotomize western biomedical . healtb services, on the one hand, and traditional health care practices on the other. Much attention has been focused on the comparison between these two approaches in the hope that they might be reconciled. The problem with this approach is twofold. In the first place, it has not always acknowledged the local, historic~1, political and economic contexts in which different approaches to health care have evolved and in the second place, health care services which belong to neither the western nor traditional healing spheres and which are driven by commercial interests have been almost completely neglected because they fall outside of the basic dichotomy. Amayeza stores have been a feature of South African towns and cities for many years. They mayor may not be run by Africans, but their clientele is almost exclusively African in this region. They deal in a bewildering variety of products and remedies, from untreated herbal and animal products to pharmaceuticals specially prepared for the African market, to Dutch and Indian Remedies. These stores both reflect transfonnations in indigenous perceptions of health care and, by virtue of the choices they offer, generate change. In this empirical study three stores in the Eastern Cape are selected for detailed study - two in King William's Town, the regional capital, and one in the small town of Peddie. The approach is holistic, emphasizing the social, political and economic context, the business histories and running of each shop, and, in particular, the perceptions and choices of a sample of the customers in each case. The success of the amayeza phenomenon derives from its eclecticism and syncretism. These stores impose neither a western nor a traditional model of health care on their clients, but offer them a range of choices that reflects the complex multicultural history of their own South African society.

The stem bark of Peltophorum africanum and Bridelia micrantha are used in South Africa traditional medicine for treatment of intestinal parasites, relieve problems and human immunodeficiency virus/ acquired immune deficiency syndrome (HIV/AIDS). The growing problem of antibiotic resistance by Helicobacter pylori the major etiological agent in gastritis, gastric cancer, peptic and gastric ulcer demands the search for novel compounds from plant based sources. This study was aimed to determine the antimicrobial activity of five solvent (ethylacetate, acetone, ethanol, methanol and water) extracts of the stem bark of P. africanum and B. micrantha on clinical strains of H. pylori in a bid to identify potential sources of cheap starting materials for the synthesis of new drugs. H. pylori strains were isolated from patients presenting with gastric related morbidities at the Livingstone Hospital, Port Elizabeth for endoscopy and confirmed following standard microbiology procedures. The plant extracts including clarithromycin were tested against 31 clinical strains of H. pylori by the agar well diffusion method. The most potent extract was evaluated by the microdilution method to determine the Minimum Inhibitory Concentration (MIC50&90), followed by the rate of kill. Preliminary phytochemical analysis was carried out. The one way ANOVA test was used to statistically analyse the results. All the extracts demonstrated anti-H. pylori activity with zone diameters of inhibition that ranged from 0 to 23 mm for the extracts and 0 to 35 mm for clarithromycin. Marked susceptibility (100%) was recorded for the ethyl acetate extract of P. africanum (P. afr. EA) and the acetone extract of B. micrantha (B. mic. A), which were statistically significant (P < 0.05) compared to all other extracts and clarithromycin. For B. micrantha ethyl acetate extract, 93.5 percent susceptibility was observed while for the control iv antibiotic, clarithromycin it was 58.1 percent. The MIC50 ranged from 0.0048 to 0.313 mg/mL for P. afr. EA, and from 0.0048 to 0.156 mg/mL for B. mic. EA; MIC90 ranged from 0.156 mg/mL to 0.625 mg/mL and 0.0048 to 2.5 mg/mL for P. afr. EA and B. mic. EA respectively. There was a significant statistical difference observed in potency of both P. afr. EA and B. mic. A compared to the two antibiotics (P < 0.05). One hundred percent killing by P. afr EA was observed at 0.05 mg/mL (½ x MIC) and 0.2 mg/mL (2 x MIC) in 66 h for strain PE466C and PE252C respectively. For B. mic. EA, 100 percent killing effect of both strains (PE430C and PE369C) was observed at 0.1 mg/mL (2 x MIC) in 66 h. Qualitative phytochemical analysis confirmed the presence of alkaloids, flavonoids, steroids, tannins and saponins in the ethyl acetate extracts of both plants, which could be a potential template of lead molecule for the design of new anti- Helicobacter pylori therapies.

No description available.

Thesis (MSc)--University of Stellenbosch, 2007. / ENGLISH ABSTRACT: The majority of South Africans still depend on the use of traditional remedies, as these are sometimes the only types of health care systems available, especially within rural communities. South Africa comprises approximately 400 000 traditional healers and an estimated 60 to 80% of individuals consulting such traditional healers. As a result, the over-harvesting of many traditional medicinal plants has become a threat to the country’s species diversity and has resulted in the scarcity of certain medicinal plant species. The non-sustainable use of traditional medicinal plants stems from their intense harvesting from the wild to supply the high demands from urban and rural markets. As a result of the escalating population growth rate; high rural unemployment; and fundamental value attached to traditional medicinal plants (socio-economic factors), the national and regional trade of traditional medicines is currently higher than it has ever been. Another reason for the increased threat to traditional medicinal plants is the degradation and weakening of customary laws that have previously regulated such resources. This study focuses on the use of traditional medicinal plants by the Setswana-speaking community for self-medication and as a form of primary health care. Research was conducted in Kimberley, Northern Cape of South Africa and focuses on the issue of the sustainability of medicinal plant use in the area, specifically on use and users as well as the acquisition of material sold by a single trader and harvesting techniques. This is to determine whether harvesting of medicinal plants is a potential threat to plant communities in the area. To address the shortcomings of medicinal anthropology the study also investigates the impacts of relocation and resettlement of various communities in the area, on plant use, methods of collection, the sustainability of the natural resource, as well as the transmission of Setswana indigenous knowledge inter-generationally. most abundant under high disturbances. Certain species reacted positively to disturbance and were most abundant in disturbed habitats. These included Elephantorrhiza elephantina and a Helichrysum sp. To minimise destructive harvesting in the Kimberley area and to ensure the sustainable harvesting of plant material, it is important that local harvesters are educated on proper harvesting techniques and that local gatherers are educated on sustainability issues as well as other ecologically fundamental issues. / AFRIKAANSE OPSOMMING: Die meeste Suid-Afrikaners is steeds afhanklik van tradisionele geneesmiddels aangesien dit soms, veral in landelike gemeenskappe, die enigste beskikbare gesondheidsorg is. Suid-Afrika het sowat 400 000 tradisionele geneeshere wat deur ’n geraamde 60% tot 80% van individue geraadpleeg word. As gevolg hiervan hou die oorontginning van talle tradisionele medisinale-planthulpbronne ’n bedreiging vir die land se spesiediversiteit in en het dit reeds tot ’n skaarste aan sekere medisinale plante gelei. Tradisionele medisinale plante word tans nievolhoubaar aangewend aangesien dit op groot skaal in die veld geoes word om in die groot vraag van stedelike en landelike markte te voorsien. As gevolg van die stygende bevolkingsgroeikoers, hoë landelike werkloosheidsyfer en die grondliggende waarde wat aan tradisionele medisinale plante geheg word (sosio-ekonomiese faktore), is die nasionale en streekhandel in tradisionele geneesmiddels tans groter as ooit tevore. Nog ’n rede vir die toenemende bedreiging van tradisionele medisinale plante is die verslapping en versagting van gewoonteregwetgewing wat voorheen sodanige hulpbronne gereguleer het. Hierdie studie fokus op die gebruik van tradisionele medisinale plante deur die Setswanagemeenskap vir selfbehandeling en as ’n vorm van primêre gesondheidsorg. Die navorsing vir die studie is in Kimberley in die Noord-Kaapprovinsie van Suid-Afrika gedoen en fokus op die kwessie van volhoubare medisinale-plantgebruik in die gebied, met bepaalde klem op gebruik en gebruikers, die verkryging van middels wat deur ’n enkele handelaar verkoop word, en oestegnieke. Die doel van die navorsing was om te bepaal of die oes van medisinale plante ’n moontlike bedreiging vir plantgemeenskappe in die gebied inhou. Om die tekortkominge van medisinale antropologie aan te pak, ondersoek die studie ook die uitwerking van die verskuiwing en hervestiging van verskeie gemeenskappe in die gebied op plantgebruik, oesmetodes, die volhoubaarheid van die natuurlike hulpbronne, asook die oordrag van inheemse Setswana-kennis oor geslagte heen. Selfbehandeling en die gebruik van tradisionele medisinale plante speel steeds ’n groot rol in Kimberley, aangesien die meeste van die individue wat aan die navorsing deelgeneem het steeds tradisionele geneesmiddels as deel van hulle kultuur en tradisie gebruik. Daar word in ’n uiteenlopende verskeidenheid plantmateriaal handel gedryf. Hoewel sommige van die middels plaaslik ingesamel word, word die meeste van ander dele van die land, en in party gevalle van buurlande soos Lesotho en Swaziland, ingevoer. Hoewel die meeste van die materiaal dus nie plaaslik ingesamel word en dus nie bepaald op hierdie studie betrekking het nie, is dit steeds aanduidend van oes- en volhoubaarheidskwessies in ander dele van die land. Die kruiekenner dryf in sewentig tradisionele medisinale-plantsoorte handel, waarvan party beskermd en erg bedreig is, waaronder Prunus africana en Warburgia salutaris wat slegs in beskermde gebiede in die land voorkom. Prunus africana is ’n gelyste spesie in CITES, aanhangsel 2. Ander bedreigde spesies sluit Ocotea bullata, Bersama lucens, Curtisia dentata en ’n Eugenia-spesie in. Die meeste van die plante wat (in Kimberley) geoes word, is in die vorm van ondergrondse bergingsorgane (uitlopers en bolle). Hoewel hierdie plante van stingelskade en die skade aan ondergrondse bergingsorgane kan herstel, vat hulle swak pos indien hulle oorgebruik en oorontgin word, en kan hulle dus mettertyd al hoe minder voorkom. In hierdie studie word die mettertydse afname in plantbevolkings deur die toename in reisafstande na insamelingspunte aangetoon. Hierdie tendens is egter nie in die handelsprys en -materiaalhoeveelhede oor die afgelope eeu weerspieël nie. Die meeste van die studiedeelnemers het bevestig dat die prys en hoeveelheid van die handelsmateriaal deurentyd betreklik stabiel gebly het. Van die teikenspesies wat vir kwesbaarheid of sensitiwiteit vir ontwrigting ondersoek is, het Withania somnifera, Boophane disticha, Dicoma anomala en Bulbine natalensis die laagste oorlewingspotensiaal en die hoogste ontwrigtingsensitiwiteit getoon. Die meeste van hierdie spesies het in baie klein hoeveelhede op die gekose terreine voorgekom. In die geval van Withania somnifera kon die negatiewe resultate egter met die laereënvalseisoen gedurende daardie betrokke jaar in verband gebring word. Hierdie spesie word oor die algemeen as ’n onkruid in ontwrigte gebiede geklassifiseer en kom meestal onder erg ontwrigte toestande voor. Sekere spesies, soos Elephantorrhiza elephantina en ’n Helichrysum-spesie, het positief op ontwrigting gereageer en het volop in ontwrigte habitatte voorgekom. Om vernietigende oestery in die Kimberley-omgewing te minimaliseer en die volhoubare ontginning van planthulpbronne te verseker, is dit belangrik dat plaaslike plukkers in gepaste oestegnieke, en plaaslike insamelaars oor volhoubaarheidskwessies en ander ekologies belangrike sake opgelei word.