This work focuses on the regression analysis of morphological parameters calculated from the ECG for estimating the position of the heart to the measuring electrodes. It consists of a theoretical analysis of the problems of ECG recording and description of the data obtained from experiments on isolated animal hearts. On the theoretical part is followed by a description of the calculation parameters suitable for regression analysis and their application in the training and testing of the following regression models to estimate the position of the heart to the measuring electrode.

Neue Methoden zur Verkehrsdatenerfassung wie die Fahrzeug-Infrastruktur-Kommunikation, der Floating Car-Ansatz und die Videodetektion eröffnen die Möglichkeit, neue Verfahren zur verkehrsabhängigen Lichtsignalanlagensteuerung zu realisieren. In dem Beitrag wird ein Verfahren beschrieben, das aus diesen Quellen Daten in Form von Fahrzeugverlustzeiten direkt zur Steuerung eines Einzelknotens verwendet. Die robuste Ausgestaltung des Verfahrens sorgt dabei dafür, dass auch mit einer lückenhaften Datenlage, wie z. B. aufgrund geringer Ausstattungsraten kommunikationsfähiger Fahrzeuge, angemessen umgegangen werden kann. Mit Hilfe einer mikroskopischen Simulationsstudie wird nachgewiesen, dass das neue Verfahren bei der Qualität des Verkehrsablaufs das gleiche Niveau wie eine traditionelle Zeitlückensteuerung erreicht oder dieses unter bestimmten Bedingungen sogar übersteigt. Mit abnehmender Ausstattungsrate ergibt sich dabei allerdings ein Qualitätsverlust, der ebenfalls mit Hilfe der mikroskopischen Simulation quantifiziert wird und wichtige Erkenntnisse für einen möglichen Praxistest liefert. / State-of-the-art traffic data sources like Car-to-Infrastructure communication, Floating Car Data and video detection offer great new prospects for vehicle-actuated traffic signal control. Due to this, the article deals with a recent approach which uses vehicles’ delay times for real-time control of traffic signals at an isolated intersection. One of the strengths of the new approach is that it can handle also incomplete data sets, e.g. caused by low penetration rates of vehicles equipped with Car-to-Infrastructure communication technology, in an appropriate manner. Based on a microscopic simulation study the high quality of this innovative approach is demonstrated, which is equal or even outperforms the well-known headway-based control. However, a decreasing penetration rate of equipped vehicles means a reduced quality of signals’ control, which is quantified in the microscopic simulation study, too, and provides useful information for tests in the field.

MASLIŠ, Martin. Isolated nominal forms in Ancient Greek. Prague, 2019. Master's thesis. Charles University. Faculty of Arts. Institute of Greek and Latin Studies. Supervisor Ján BAKYTA. The submitted thesis is a study of isolated nominal forms in Ancient Greek undergoing semantic change. Synchronically isolated lexemes are defined as forms which cannot be classed with their respective cognates by the speakers due to formal disparities. This leads to increased opacity which in turn hampers the mapping of meaning onto the forms during the acquisition phase. Accordingly, a hypothesis that isolated forms are susceptible to semantic change is tested. An argumentation is developed based on the assumed information structure in the mental lexicon of speakers and the mechanism of word meaning acquisition. This process allows for reanalysis on the part of speakers which results in semantic change from the diachronic point of view. Lexemes which have been selected according to the proposed research method are organized in a dataset and their occurrences textually analysed. A synthesis aims to describe the mechanism of semantic change for the transparent as well as isolated forms. Keywords: mental lexicon, derivational family, isolated forms, semantic change, deetymologization

1,25-dihydroxyvitamin D3 [1,25(0H)2D3] has been shown to promote phosphate transport rapidly in the perfused duodenal loop, relative to controls, reaching treated/av basal at T = 40 min = 1.82 ± 0.42 and 1.11 ± 0.21, respectively. By using isolated chick enterocytes, studies were undertaken to determine whether 1,25(0H)2D3 has a direct effect on isolated intestinal cells that is manifested by either enhanced uptake or extrusion of phosphate. In time course studies, with 4- to 8-wk-old chicks, 32P uptake in enterocytes at 10 min after addition of test substance was 0%, 130%, 151%, and 123% of controls for 10 pM, 50 pM, 130 pM, and 300 pM 1,25(0H)2D3, respectively. The metabolite 24,25- dihydroxyvitamin D3 [24,25(0H)2D3] exerted an inhibitory effect on phosphate uptake by 1,25(0H)2D3 at a concentration of 130 pM. This result was in agreement with perfusion studies and supports the physiological relevance of isolated cell studies. For signal transduction studies, isolated enterocytes were incubated with 20 µM forskolin (an activator of protein kinase A), 100 nM phorbol ester (an activator of protein kinase C), or 2 µM BAY K 8644 (a calcium channel activator). Enhanced 32P levels relative to controls were found for phorbol ester (126% of controls at T = 7 min, P < 0.05) and BAY K 8644 (150% of controls at T = 7 min, P < 0.05) but not for forskolin, suggesting involvement of protein kinase C and calcium channel signal transduction pathways in uptake. These results paralleled those observed for the perfused duodenal loop. For aging studies, white leghorn roosters were raised for 7, 14, and 28 wk prior to experiments. These studies showed a 1,25(0H)2D3-mediated increase in 32P uptake in isolated cells at 7 wk, but not at 14 or 28 wk. Further analysis of isolated basal lateral membrane (BLM) on SDS-PAGE followed by Western analysis with a well characterized antibody (Ab099) showed a decreased expression of the putative membrane receptor for 1,25(0H)2D3 with increasing age, paralleling the results obtained for 32P uptake in isolated intestinal cell studies. Analyses of 1,25(0H)2D3 effect on protein kinase C activity likewise revealed hormone-mediated stimulation in cells from 7-wk- old chicks, with decreasing responsiveness at a later age. The combined results indicate a physiologically important role for 1,25(0H)2D3 membrane-initiated phosphate uptake in enterocytes of young, rapidly growing animals. Furthermore, these studies validate the use of isolated intestinal cells for further studies on ribozyme-mediated ablation of the 1,25(0H)2D3 membrane receptor function.

Indiana University-Purdue University Indianapolis (IUPUI) / There are various types of power electronic converters available in recent days. In some applications (e.g. PC power supply), it is required to supply more than one load from a single power supply. One of the main challenges while designing a power converter is to increase its e ciency especially when the number of power switches employed is relatively large. While several loads are supplied from a single source, if the power loss in the switches cannot be reduced, then the expected utilization of using a single source is not very feasible. To reduce the loss and increase e ciency, the thesis presents a novel design with reduced number of switches. The scope of this thesis is not limited to the dc-dc converter only, the converter to supply three phase ac loads from a single dc source is also presented. This discussion includes an improved fault tolerant configuration of the inverter part. The generated waveforms from the simulations are included as a demonstration of satisfactory results.

Pages 19 to 23 have been omitted because of Revision / Elizabethan prose fiction has been virtually ignored for a long time. The question of rhetoric in this fiction is an extremely complex issue, and studies which have examined this aspect are usually stylistic analyses that fragment the works by dissecting isolated passages for stylistic data concerning an author's manipulation of particular schemes and tropes. This approach has often tended to ignore the possibility that larger ideals and attitudes may underlie the use of rhetorical figures (i.e. elocutio) in particular passages. While this dissertation does not attempt to resolve the problems of the relationship between rhetorical training in the grammar schools and Elizabethan fiction, or between the English vernacular rhetorics and Elizabethan fiction, it offers some idea about what these writers thought about rhetoric beyond its status as ornamentation. This thesis tries to discover what these writers thought about the possibilities of rhetorical training --that is, about its moral status as an art of persuasion. In my view, the major writers of Elizabethan prose fiction dramatize the abuses of verbal skills; they explore some of the techniques of deception, distortion and manipulation that are afforded by rhetorical training. The subject-matter of this fiction is largely concerned with verbal methods of persuasion that manipulate and distort, that rely on false logic and dishonesty; these writers are concerned with rhetorical attempts to change the face of the "real" world in order to justify a particular idea, action, or belief. My thesis explicates the prose fictional works of Gascoigne, Lyly, Sidney, Nashe and Deloney with this theory in mind. As well as suggesting the ways in which rhetoric is handled as a subject in a variety of fictional contexts, my thesis also explicates the rhetorical strategies which these authors themselves use to involve their reader in evaluating rhetoric. / Thesis / Doctor of Philosophy (PhD)

Particulate composites are widely used in many aerospace applications such as protective coatings, adhesives, or structural members of a body and their mechanical properties and behavior have gained increasing significance. The addition of modifiers such as alumina generally leads to improved mechanical properties. This addition also enables the non-invasive study of the load transfer between the particle and the matrix. Understanding the load transfer between the particulate and the matrix material is the first step to understanding the behavior and mechanical properties of the composite as a whole. In this work, samples with an isolated alumina particle embedded in an epoxy matrix were created to replicate the ideal assumptions for many particulate mechanics models. In separate experiments, both photo stimulated luminescent spectroscopy (PSLS) and synchrotron radiation were used to collect the spectral emission and diffraction rings, respectively, from the mechanically loaded samples. The PSLS data and XRD data are shown to be in qualitative agreement that as particle size is increased, the load transferred to the particle also increased for the range of particle sizes tested. This trend of increasing load transfer with increasing particle size is compared with the classical Eshelby model. Results from this work provide experimental insight into the load transfer properties of particulate composites and can serve to experimentally validate the theoretical load transfer models that currently exist.

This thesis report details the design and construction of non-isolated DC-DC converters to create a Multiple Input Single Output (MISO) converter for combining multiple renewable energy sources into one single output. This MISO uses the four-switch buck-boost topology to output a single 48V from multiple nominal 24V inputs. The MISO converter implements a modular approach to deliver 1800W output power. Each module in the MISO is rated at 600W and they share the output power equally. Hardware results show that the converter produces 1800W of output power from three sources with 96.4% efficiency. Each module also demonstrates equal sharing feature of the MISO converter.

The use of nanofluids as heat transfer fluids has received a lot of attention from the heat transfer research community. Due to the increased thermal conductivity of nanofluids over their base fluids, the number of nanofluids scientific publications increased significantly in the past decade. The effects of the heated surface roughness, nanoparticles and surfactant concentrations on pool boiling of nanofluids have been thoroughly investigated. However, contradicting findings have been observed under what appeared to similar test conditions. In this experimental investigation, two boiling surfaces have been prepared with an average surface roughness of 6 and 60 nm using high precision machining. Alumina Oxide-Water based nanofluids have been used in this investigation. The initial nanoparticle size reported by the manufacturer is 10 nm. The nanoparticles concentration has been kept at 0.05 wt. %. A Sodium Dodecylbenzenesulfonate (SDBS) surfactant has been added to the nanofluids in order to improve its stability. Results showed that the nanofluids boiling performance depended on the boiling surface roughness. The heat transfer coefficient (HTC) obtained in the case of the smooth, mirror finished surface showed an enhancement of 205% with respect to pure water. This trend was reversed in the case of the rough surface which is believed to be due to significant nanoparticles deposition. The HTC obtained with the rough surface was 12% lower than that of pure water. The effect of the surfactant concentration on nanoparticles deposition has been investigated by changing the surfactant concentration from 0.1 to 1.0 wt. %. In the case of the rough surface, the increase of surfactant concentration was found to reduce the formation of the nanoparticles deposition layer. The HTC obtained with the higher surfactant concentration was increased by 46 %. The effect of nanoparticles concentration on the smooth surface shows an unexpected trend of 20 % reduction of the transfer rate of the nanofluids coupled with the increase of the nanoparticle concentration from 0.05 to 0.1 wt. %. However all concentrations showed heat transfer enhancement with respect to pure water. The minimum heat transfer coefficient ratio enhancement was 11 % using 0.1 wt. % nanofluids with respect to pure water. Since nanoparticles deposition has been observed and attributed to micro-layer evaporation, an investigation has been carried out to examine the nucleation process during the pure water and nanofluids pool boiling. The bubble growth rate in both cases was analyzed at different wall degrees of superheat ranging from 104.3 to 105.9 ºC. In addition, the bubble departure diameter and frequency have been measured and compared for both cases. The nanofluid bubble size was about 80 % smaller than that of pure water. The nanofluid bubble departure had almost constant frequency of 500 Hz over the range of wall superheats whereas the maximum bubble frequency in the case of pure water was 22.72 Hz. / Thesis / Master of Applied Science (MASc)

京都大学 / 新制・課程博士 / 博士(工学) / 甲第24212号 / 工博第5040号 / 新制||工||1787(附属図書館) / 京都大学大学院工学研究科社会基盤工学専攻 / (主査)教授 中北 英一, 准教授 山口 弘誠, 准教授 佐山 敬洋 / 学位規則第4条第1項該当 / Doctor of Philosophy (Engineering) / Kyoto University / DFAM