No description available.

No description available.

This paper presents research on isolated human remains from Grasshopper Pueblo and analyzes the processes by which bone becomes displaced from burials. Isolated human bone has never been systematically examined, which represents a significant gap in the study of the prehistoric American Southwest. This research is important because it is the first determination of the pattern of isolated bone found at an archaeological site and the formation processes that are responsible. It is also relevant for the creation of a standard isolated bone methodology and because it enables a better understanding of burial assemblages and anomalous assemblages of culturally modified bone.Subadults dominate the assemblage and larger elements are better represented than smaller elements. Most of the modifications present are postmortem but perimortem breakage and toolmarks are also present. This research produced a baseline of detailed data on isolated human bone in which patterns and anomalies can be inferred; the results suggest multiple causes of the isolation of the specimens, including prehistoric cultural disturbance, rodent disturbance, and the process of excavation.

On June 11, 2009, the World Health Organization declared a global influenza pandemic due to a novel influenza A virus subtype of H1N1. Public health emergencies, such as an influenza pandemic, can potentially impact disadvantaged populations disproportionately due to underlying social factors. Canada???s First Nation population was severely impacted by the 2009 H1N1 influenza pandemic. Most First Nation communities suffer from poor living conditions, impoverished lifestyles, lack of access to adequate health care, and uncoordinated health care delivery. Also, there are vulnerable populations who suffer from co-morbidities who are at a greater risk of falling ill. Moreover, First Nation communities that are geographically remote (nearest service center with year-round road access is located over 350 kilometers away) and isolated (only accessible by planes year-round) face additional challenges. For example, transportation of supplies and resources may be limited, especially during extreme weather conditions. Therefore, remote and isolated First Nation communities face unique challenges which must be addressed by policy planners in order to mitigate the injustice that may occur during a public health emergency. The Assembly of First Nations noted that there has been very little inclusion of First Nations??? input into current federal and provincial pandemic plans. Disadvantaged groups know best how they will be affected by a public health emergency and are able to identify barriers and solutions. Therefore, the objective of my research was to gain retrospective insight into the barriers faced by three remote and isolated First Nation communities of sub-arctic Ontario (i.e., Fort Albany, Attawapiskat, and Kashechewan) during their 2009 H1N1 pandemic response. Culturally-appropriate community-based suggestions for improvement of existing community-level pandemic plans were also elicited. Collected data informed modifications to community-level pandemic plans, thereby directly applying research findings. Being a qualitative community-based participatory study, First Nation community members were involved in many aspects of this research. Semi-directed interviews were conducted with adult key informants (n=13) using purposive sampling of participants representing the three main sectors responsible for health care services (i.e., federal health centers, provincial hospitals, and Band Councils). Data were manually transcribed and coded using deductive and inductive thematic analysis to reveal similarities and differences experienced within and between each community (and government body) regarding their respective pandemic response. Another round of semi-directed interviews (n=4) and community pandemic committee meetings were conducted to collect additional information to guide the modifications to the community-level pandemic plans. Reported barriers due to being geographically remote and isolated included the following: overcrowding in houses, insufficient human resources, and inadequate community awareness. Primary barriers faced by government bodies responsible for health care delivery were reported as follows: receiving contradicting governmental guidelines and direction from many sources, lack of health information sharing, and insufficient details in community-level pandemic plans. Suggested areas for improvement included increasing human resources (i.e., nurses and trained health care professionals), funding for supplies, and community awareness. Additionally, participants recommended that complementary communication plans should be developed. As suggested by participants, community-specific information was added to update community-level pandemic plans. Remote and isolated First Nation communities faced some barriers during their 2009 H1N1 health sector pandemic response. Government bodies should focus efforts to provide more support in terms of human resources, monies, and education. In addition, various government organizations should collaborate to improve housing conditions, timely access to resources, and the level of coordination regarding health care delivery. Furthermore, as pandemic plans are dynamic, government bodies should continue to aide First Nation communities with updating their community-level pandemic plans to satisfy their evolving needs. These recommendations should be addressed so that remote and isolated western James Bay First Nation communities and other similar communities can be better prepared for the next public health emergency.

WiFi is becoming common in households and digital devices needs to support it. At the same time the devices are getting smaller and the Ethernet port may seem superfluous. When testing these devices the test environment needs to be able to provide WiFi connectivity. The tests may be focused on testing WiFi but it could also be the only network connectivity and thus needs to be very reliable. With a large number of devices in a small physical area a normal WiFi setup would have a density of devices that is too high for today’s1 WiFi standards. A combination of wired physical medium and physical isolation was considered.

No description available.

No description available.

No description available.

Ao longo dos anos a implementação das políticas de saneamento básico no Brasil foram evoluindo gradativamente, porém as metas de universalização não serão alcançadas até 2030. Os piores índices historicamente se concentram nas regiões norte e nordeste, sendo mais acentuados nas áreas rurais. O Amapá é o estado mais preservado do país, abrange em seu território diversas modalidades de áreas protegidas e comunidades tradicionais, dentre elas a comunidade Água Branca do Cajari, localizada na Reserva Extrativista do Rio Cajari, objeto de estudo desta Dissertação, que consistiu na formulação e avaliação de alternativas para suprir a demanda de água potável e ao encaminhamento seguro dos esgotos sanitários. Para o alcance dos objetivos, foram realizadas duas campanhas de campo, com o intuito de conhecer o perfil social, econômico e ambiental da comunidade, através da aplicação de questionários e observação in situ, avaliação da qualidade das águas destinadas ao consumo humano, através de análises físico-químicas e microbiológicas e estimativas da geração de esgoto. A proposição das alternativas foi feita a partir do dimensionamento e avaliação dos custos de instalação, operação e manutenção ao longo do horizonte de planejamento de 20 anos. Os orçamentos foram elaborados a partir de dados disponíveis na literatura técnica e a composição dos custos por pesquisas de preço e fontes oficiais como o SINAPI. Treze poços freáticos são utilizados pela população que reside na parte alta da comunidade, enquanto os que moram na parte baixa, retiram diretamente do rio, adicionam polímero que adquirem informalmente para a clarificação das águas, em média 95% da população afirma realizar a desinfecção com hipoclorito de sódio, sendo que 41,1% da população tem acesso ao mínimo estabelecido pela ONU e 7,6% abaixo do recomendado. Estavam em não conformidade, de acordo como o que estabelece a Portaria n° 2.914/2011 do Ministério da Saúde, 75% das amostras analisadas para o parâmetro pH, 62,5% para turbidez, 90% para coliformes totais/Escherichia coli. Cerca de 82,3% do esgoto séptico gerado é encaminhado a fossas negras, e 13% das unidades domiciliares não dispõe de banheiro. O custo total dos sistemas foi de: sistema de bombeamento fotovoltaico 430.644,97 R$ (0,18 R$/hab.dia); aproveitamento de água de chuva de 432.236,72 R$ (0,19 R$/hab.dia); filtro lento domiciliar 7.326.27 R$; sistema de desinfecção solar (SODIS) 9.768,54 R$ e para o tratamento de esgoto sanitário unifamiliar, fossas sépticas \"Imhoff\" e sumidouro 434.371,32 R$ ou 0,19 R$/hab.dia. Portanto, verificou-se que as alternativas avaliadas são viáveis economicamente e operacionalmente. A efetividade da implantação das tecnologias de tratamento de água e esgoto em comunidades isoladas ou de difícil acesso na Amazônia devem ser precedidas de estudos socioeconômicos, ambientais e culturais. / In the world, about 748 million of people do not have access to a potable water, more than 30% of the world population do not have appropriate installations and 1 million of people do their physical necessities in open areas, of theses, nine out ten are in rural areas. The policies about basic sanitation in Brazil gets better long of the years, but the marks for universalization cannot be touched until 2030. The indications get worst in north and northeast, especially in the countryside. Amapá is the most preserved state of Brazil, that has in its territory many spaces of protected areas and traditional communities, one of them is Àgua Branca do Cajarí, located in an extractive reserve, and is the focus of this issue, whose objective is propose and estimate better ways to get a high quality of water and sanitary wastewaters. To get better results, it was necessary to visit at these areas to know the community social, economic and environmental profile through questionnaires and in situ observation, beside doing physic-chemical and microbiological analyzes. The proposition of the best alternatives was made by starting from the estimative of installation and conservation along of 20 years, getting the present prizes. Those estimative were based on technical literature, prizes researched and official sources as SINAPI. Thirteen phreatic wells are used by people who live on the higher part of the community while people that live on the lowest part need to take water right from the river, put some polymer that is taken informally to clarify the water. About 95% of people say that use sodium hypochlorite in water, but just 41% has the least required by UNO and 7.6% is low from what is demanded. According with the governmental decree N. 2914/2011, 75% of the sample that were analyzed showed to the pH parameter; 62.5% for turbidity; 90% for total coliforms/ Escherichia coli. About 82.3% of the septic sewer created is sent to black cesspool and 13% of the houses do not have a bathroom. The total cost of the systems was about R$ 430,644.97 for a photoelectric system (0.18 R$/resident.day). The perforation and preservation of the wells were not considered; R$ 432,236.72 if use rain water (0.19 R$/resident.day). R$ 7,326.27 for slow domiciliary filter. R$ 9,768.54 for solar disinfection system and R$ 434,371.32 for unifamilial sanitary sewer treatment, septic tank \"imhoff\" and escape hole (0.19 R$/resident.day). Therefore, it was possible to see that the alternatives analyzed were economically and operationally possible. The implementation of water and sewer treatment technologies in isolated communities of by difficult access in Amazonia must be followed by socioeconomic, environmental and cultural studies.

Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmacology & Toxicology Student: Hana Pešková Supervisor: PharmDr. Marie Vopršalová, CSc. Title of diploma thesis: Effects of some flavonoids in isolated rat aortic rings Flavonoids with their wide range of effects are known for having positive influence on human health. It mainly concerns significant antioxidant and anti- inflammatory characteristics and cardiovascular diseases incidence reducing effects. The aim of this study was examination of vasorelaxant effects of selected flavonoids from isoflavonoid group: formononetin, isoformononetin, prunetin and ononin, occuring especially in Fabaceae family. The vasorelaxation potential of tested substances was examinated in in vitro conditions on isolated aortic rings of rat. The effect of increasing doses of individual flavonoids on preparation, with intact endothelium after previous precontraction with norepinefrine, was monitored (10-5 M). From measured values, there were DRC curves, EC50 values created and an evaluation was made. According to analysis of the results, the most significat activity has fromononetin (EC50 2,081 . 10-5 M) and isoformononetin (EC50 2,081, 10-5 M). Ononin showed almost no vasodilatory effect.