This diploma thesis contains the basic theoretic information which is needed for implementing of the safety management at the small and middle companies in Czech republic. The thesis explicates the methodology of the Self-Audit Handbook for SMEs and describes self audit applications in the industry.

The main objective of this thesis is to carry out a safety audit in a foundry using Self-Audit Handbook for SMEs. Based on the results is evaluated level of occupational safety in the company and are recommend measures for improvement. Research in the field of auditing OH&S management systém is also performed.

The main content of the diploma thesis is the implementation and evaluation of the safety audit in selected company using the manual Self-Audit Handbook for SMEs. The identification of security risks in the company is also performed by statistical analysis of accidents at work in the company and evaluating the most common causes of accidents. Based on the detected weaknesses are proposed measures to eliminate them.

The vibrational dynamics of theOH stretching mode in Ba(ClO4)2 trihydrate are investigated by means of femtosecond infrared spectroscopy. The sample offers plane cyclic water trimers in the solid phase that feature virtually no hydrogen bond interaction between thewater molecules. Selective excitation of the symmetric and asymmetric stretching leads to fast population redistribution, while simultaneous excitation yields quantum beats, which are monitored via a combination tone that dominates the overtone spectrum. The combination of steady-state and time-resolved spectroscopy with quantum chemical simulations and general theoretical considerations gives indication of various aspects of symmetry breakage. The system shows a joint population lifetime of 8 ps and a long-lived coherence between symmetric and asymmetric stretching, which decays with a time constant of 0.6 ps.

Elevation in serum parathyroid hormone (PTH) often accompanies vitamin D deficiency and renal impairment. PTH elevation in renal failure is viewed as an unfavorable development. Evidence is increasing that PTH elevation may be associated with increased morbidity and mortality. In many instances these PTH effects appear to be independent of vitamin D status. PTH mediates its effects through the ubiquitous type 1 PTH/PTH-related peptide receptor, which is notably present in the cardiovascular system. Increased PTH may promote cardiovascular disease through diminished cardiac contractility, enhanced coronary risk, and cardiac valvular and vascular calcification. High PTH levels appear to be linked to the metabolic syndrome and are aligned with hyperlipidemia, decreased insulin sensitivity, and, perhaps, decreased insulin secretion. Increased PTH also is associated with neuroendocrine activation, increased sympathetic activity, and endothelial stress. The relation between PTH and vitamin D is complex and may show significant threshold variations, especially when calcium intake, age, and race are considered. Moreover, evidence is increasing that fragments of PTH may not only be hormonally active but also may have opposing effects to PTH. Despite these caveats, PTH values provide useful clinical diagnostic and prognostic information in monitoring many chronic ailments such as heart and renal failure and multiple sclerosis.

In this work, a high-performance hybrid supercapacitor is assembled with N-doped reduced graphene oxide (N-rGO) decorated with Fe2O3 (Fe2O3/N-rGO) as the anode, and NiCo layered double hydroxide integrated with conductive Co(OH)2 (NiCo LDH/Co(OH)2) as the cathode. The two main pseudo-capacitive materials are modified by different materials (N-rGO and Co(OH)2) to enhance the conductivity. For anode, the Fe2O3 nanoparticles are uniformly dispersed on N-rGO via a facile solvent-thermal method. The highly conductive Fe2O3/N-rGO exhibits a superior capacitance of 912.9F/g at 1 A/g and retains 84% at 30 A/g. The NiCo LDH/Co(OH)2 cathode also synthesized by a convenient solvent-thermal method delivers a high specific capacitance of 2220.0F/g at 1 A/g and retains 70% at a high current density of 50 A/g. Utilizing these electrodes, we successfully fabricate a hybrid battery-like supercapacitor with an excellent energy density of 103.3 Wh/kg at an outstanding power density of 790 W/kg, an excellent capacitance of 296.3F/g at 1 A/g and a remarkable cyclic stability with 92% retention after 1000 cycles at 10 A/g. Due to the elaborately designed electrode materials, the battery-like supercapacitor exhibits excellent electrochemical properties and is an inspiration for future energy storage devices.

Past literature has supported the supplementation of 25-OHD3 into poultry diets to reduce leg issues and improve muscle accretion. In addition, exogenous feed enzymes are included into poultry diets to increase nutrient utilization. The first objective of this thesis was to determine the effects of different sources and levels 25-OHD3 supplementation on D0-53 Ross x Ross 708 male broiler performance, processing yield, tibia ash, serum Ca and 25-OHD3 status. Data demonstrated that 25-OHD3 supplementation into diets with Low VitD3 (165 IU/kg) can improve broiler performance compared to High VitD3 (2756 IU/kg). The second objective was to investigate the effects of varying phytase inclusion with different xylanase levels on D0-56 Ross x Ross 708 male broiler performance, processing yield and tibia ash. Data exhibited some performance benefit (D46 and D56) when utilizing phytase (1000 and 1500 FTU/kg) with 1500 EPU/kg xylanase and phytase (250 and 1500 FTU/kg) with 3000 EPU/kg xylanase.

The intent of this project was founded upon the need to train students in the techniques of radio astronomy with the purpose of establishing a radio telescope in order to teach the principles and practice of radio astronomy.This document describes the theory, research, to establish the 1st generation radio telescope system within the Department of Physics and Astronomy at Brigham Young University. Included are introductions to: (1) The nature of star forming regions in the spiral arm structure of the galaxy, H I (the hydrogen spin-flip transition) and OH MASERS, (2) The of terminology used with the system components and their measurements, (3) The characteristics of the imaging system and its limitations, and (4) Future work and plans. Within the body of this work, I also present an introduction to the purpose, architectural design, as well as a brief description of some of the system level functions and associated equipment that constitute the development infrastructure for the 2nd generation radio astronomy system.The major work accomplished includes history, some of the fundamental theory behind radio astronomy, significant aspects of the theory behind the system, building of the system, its calibration and characteristics as well as next steps

Polycyclic aromatic hydrocarbons (PAH) are a class of environmental pollutants consisting of a minimum of two fused aromatics rings originating from the incomplete combustion of organic matter and/or anthropogenic sources. Numerous possible anthropogenic and natural sources make the presence of PAH ubiquitous in the environment. The carcinogenic nature of some PAH and their ubiquitous presence makes their chemical analysis a topic of environmental and toxicological importance. Although environmental monitoring of PAH is an important step to prevent exposure to contaminated sites, it provides little information on the actual uptake and subsequent risks. Parent PAH are relatively inert and need metabolic activation to express their carcinogenicity. Covalent binding to DNA appears to be the first critical step in the initiation of the tumor formation process. To this end, the determination of short term biomarkers – such as monohydroxy-PAH metabolites (OH-PAH) - fills an important niche to interpret actual PAH exposure levels, prevent extreme body burdens and minimize cancer risk. One would certainly prefer an early warning parameter over a toxicological endpoint – such as DNA-adducts – indicating that extensive damage has already been done. Several methods have been developed to determine OH-PAH in specific tissue or excreta and food samples. The general trend for the analysis of OH-PAH follows the pattern of sample collection, sample clean-up and pre-concentration, chromatographic separation and quantification. Popular approaches for sample clean-up and preconcentration include liquid-liquid extraction (LLE) and solid-phase extraction (SPE). Chromatographic separation and quantification has been based on high-performance liquid iv chromatography-room temperature fluorescence detection (HPLC) and gas chromatographymass spectrometry (GC-MS). Although chromatographic techniques provide reliable results in the analysis of OHPAH, their experimental procedures are time consuming and expensive. Elution times of 30-60 minutes are typical and standards must be run periodically to verify retention times. If the concentrations of target species are found to lie outside the detector’s response range, the sample must be diluted and the process repeated. On the other end of the concentration range, many samples are “zeroes,” i.e. the concentrations are below detection limits. Additional problems arise when laboratory procedures are scaled up to handle thousands of samples under mass screening conditions. Under the prospective of a sustainable environment, the large usage of organic solvents is one of the main limitations of the current chromatographic methodology. This dissertation focuses on the development of a screening methodology for the analysis of OH-PAH in urine and milk samples. Screening techniques capable of providing a “yes or no” answer to OH-PAH contamination prevent unnecessary scrutiny of un-contaminated samples via conventional methods, reduce analysis cost and expedite the turnaround time for decision making purposes. The proposed methodology is based on capillary zone electrophoresis (CZE) and synchronous fluorescence spectroscopy (SFS). Metabolites extraction and pre-concentration is achieved with optimized SPE, LLE and/or QuEChERS (quick, easy, cheap, effective, rugged and safe) procedures. The small sample and extracting solvent volumes facilitate the simultaneous extraction of numerous samples via an environmentally friendly procedure, which is well-suited for routine monitoring of numerous samples. Sample stacking is successfully implemented to improve CZE limits of detection by two orders of magnitude. The unique electrophoretic pattern of positional isomers of OH-PAH demonstrates the potential of CZE for v the unambiguous determination of metabolites with similar chromatographic behaviors and virtually similar fragmentation patterns. The direct determination of OH-PAH without chromatographic separation is demonstrated via SFS. The non-destructive nature of SFS provides ample opportunity for further metabolite confirmation via chromatographic techniques

No description available.