741 |
Role of cysteine proteinases in IGF-1R turnover, invasion and metastasisNavab, Roya. January 1999 (has links)
No description available.
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742 |
The effect of hormone replacement therapy on the risk of colorectal cancer in postmenopausal women /Csizmadi, Ilona January 2002 (has links)
No description available.
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743 |
Oligonucleotide microarray analysis of chromosome-X gene expression in human epithelial ovarian cancer cell linesBenoit, Marie-Helene January 2004 (has links)
No description available.
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744 |
Determinants of waiting time from initial diagnostic procedure to surgery among women with localized breast cancer in Quebec, 1992-1997Shen, Ningyan, 1961- January 2001 (has links)
No description available.
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745 |
Identification of the DNA methylation machinery, its regulation and uses as potential anticancer therapeuticsRamchandani, Shyam. January 1999 (has links)
No description available.
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746 |
Analysis of the combined primary data from case-control studies of residential radon and lung cancer : a pilot study of three North-American sitesCatalan, Vanessa Spurll. January 1998 (has links)
No description available.
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747 |
Functional characterization of progranulin in wound healing and tumorigenesisHe, Zhiheng, 1971- January 2001 (has links)
No description available.
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748 |
Molecular studies on the therapeutic implications and regulation of connexin 43Carystinos, George D. January 2000 (has links)
No description available.
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749 |
The Development of a New Measure of Linear Accelerator Throughput in Radiation Oncology Treatment Delivery - The Basic Treatment Equivalent (B.T.E.).Delaney, Geoffrey Paul, SWSAHS Clinical School, UNSW January 2001 (has links)
The measurement of productivity in health care is difficult. Studies in various specialty disciplines of medicine have identified that the variation in complexities (casemix) between departments or hospitals will vary and therefore will affect any basic productivity statistics that are produced. Radiation oncology is a discipline of medicine where no such studies into radiotherapy casemix variations and the effect that these may have on productivity measures have been performed, despite the high capital expenditure involved in the delivery of radiotherapy. Radiation oncology productivity on linear accelerators is currently measured by the number of patients treated or number of treatment fields treated per unit time (usually per hour). These statistics have been collected for many years and productivity assessments were made on the variations in these statistics that exist between departments. However, these statistics do not consider the variations in casemix that occur between departments. These complexity differences may be quite marked and therefore may strongly influence the ability of a department to achieve a high patient or treatment field throughput. This may be seen as 'reduced productivity' with no consideration of the complexity of the caseload seen in the department. In addition, future technological changes that improve patient outcome may be introduced. These changes may make treatment more complex. Using older measures of productivity such as fields per hour or patients per hour will not consider these technological changes and the subsequent changes in complexity and hence departments may be seen as less productive in the future using current methods of analysis unless a more valid measure of productivity that considers complexity variations is introduced. There have only been 3 previous attempts at developing measures of linear accelerator productivity. Each of these models have been developed empirically and have not been clinically validated. No previous attempts have been made in determining a scientifically-derived complexity model that considers the variations in treatment technique. This thesis describes research performed between 1995 and 2001. This research study???s primary aims were to study the factors that affect radiotherapy treatment time and treatment complexity and to develop a model of linear accelerator productivity that does consider complexity variations in radiotherapy treatment delivery. This model is called the Basic Treatment Equivalent (B.T.E.). This series of trials examines the old models of linear accelerator productivity, describes the derivation and validation of the BTE model both in Australasia and the United Kingdom, identifies the factors that contribute to treatment time and treatment complexity, describes the development of a pilot model of productivity of gynaecological brachytherapy and outpatient chemotherapy using similar BTE methodology, discusses the potential uses of the BTE model, recent independent reviews of BTE by other groups, and the advantages and disadvantages of using such a model. This research has shown that it is possible to identify the various factors that contribute to treatment time and treatment complexity and to derive a model of linear accelerator productivity that considers the variations in complexity. The BTE model has been clinically validated in Australia, New Zealand and a couple of departments in the United Kingdom and Canada and has been adopted as a new measure by various groups. It requires regular updating to maintain currency particularly as there are frequent improvements in radiation treatment technology. Future studies should identify the differences these technological enhancements make to productivity. The BTE derived from outpatient chemotherapy delivery and gynaecological brachytherapy delivery shows promise although these models require further research with the assistance of other departments.
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750 |
Ur patientens synvinkel : att leva med cancerrelaterad fatigueLindberg, Sandra, Olofsson, Malin January 2008 (has links)
<p><p><strong><strong>Bakgrund: </strong></strong>Fatigue är ett cancerrelaterat symtom och drabbar ca 61- 100 % av cancer patienterna. Det är en långdragen trötthet som gör det svårt för de drabbade att leva ett normalt liv. <strong>Syftet </strong>med arbetet var att belysa cancerrelaterad fatigue samt se hur patienter anpassar sig till att leva med detta cancerrelaterade symtom. <strong>Metod: </strong>En litteraturöversikt genomfördes, med artikelsökning i databaserna PubMed och Cinahl. Innehållsanalys gjordes på funna artiklar, totalt inkluderades 14 artiklar i resultatet. <strong>Resultat: </strong>Patienter fann egna strategier för att handskas med fatigue, det kunde vara att sova en stund eller distrahera sig med något annat. Patienterna ville ha information om fatigue, men kände ofta att de inte fick det av sjukvårdspersonalen, de ville också ha stöd och förståelse från sin omgivning, något som det inte alltid fick. <strong>Diskussion: </strong>Enligt författarna måste patienterna få sjukdomsinsikt och information om fatigue för att hitta sina egna strategier så inte fatigue tar över vardagen. Sjuksköterskor bör vara insatta i patienternas situation eftersom patienterna hellre vill diskutera sina problem med sjuksköterskor än läkare. <strong>Slutsats: </strong>Fatigue är ett ämne som det bör forskas mer</p></p>
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