abstract: As the application of interactive media systems expands to address broader problems in health, education and creative practice, they fall within a higher dimensional space for which it is inherently more complex to design. In response to this need an emerging area of interactive system design, referred to as experiential media systems, applies hybrid knowledge synthesized across multiple disciplines to address challenges relevant to daily experience. Interactive neurorehabilitation (INR) aims to enhance functional movement therapy by integrating detailed motion capture with interactive feedback in a manner that facilitates engagement and sensorimotor learning for those who have suffered neurologic injury. While INR shows great promise to advance the current state of therapies, a cohesive media design methodology for INR is missing due to the present lack of substantial evidence within the field. Using an experiential media based approach to draw knowledge from external disciplines, this dissertation proposes a compositional framework for authoring visual media for INR systems across contexts and applications within upper extremity stroke rehabilitation. The compositional framework is applied across systems for supervised training, unsupervised training, and assisted reflection, which reflect the collective work of the Adaptive Mixed Reality Rehabilitation (AMRR) Team at Arizona State University, of which the author is a member. Formal structures and a methodology for applying them are described in detail for the visual media environments designed by the author. Data collected from studies conducted by the AMRR team to evaluate these systems in both supervised and unsupervised training contexts is also discussed in terms of the extent to which the application of the compositional framework is supported and which aspects require further investigation. The potential broader implications of the proposed compositional framework and methodology are the dissemination of interdisciplinary information to accelerate the informed development of INR applications and to demonstrate the potential benefit of generalizing integrative approaches, merging arts and science based knowledge, for other complex problems related to embodied learning. / Dissertation/Thesis / This video shows a demonstration of the home-based AMRR system in use with a stroke survivor. Participant is shown receiving instructions, followed by performance of one interactive Level 1 set of reaching to grasp and lift a portable cylinder. / This video shows a demonstration of the home-based AMRR system in use with a stroke survivor. Participant is shown performing an interactive Level 1 set of reaching to touch a flat object. / This video shows a demonstration of the home-based AMRR system in use with a stroke survivor. Participant is shown performing an interactive Level 2 set of reaching to grasp a cone. / This video shows a demonstration of the home-based AMRR system in use with a stroke survivor. Participant is shown performing an interactive Level 3 set of reaching to grasp and transport the cylinder between two locations. / This video shows a demonstration of the home-based AMRR system in use with a stroke survivor. Participant is shown setting up the targets used for training. / This video shows the clinical AMRR feedback for trajectory performance and speed. Video depicts the image formation and plays the musical phrase generated by a reach that is (1) efficient, (2) with horizontal trajectory deviation, (3) and slow. / This video shows the clinical AMRR feedback for joint function and compensation. Video depicts (1) image rotation for wrist rotation, (2) the orchestral sound for elbow extension, (3) the shoulder compensation sound and (4) the torso compensation sound. / This video shows the clinical AMRR feedback demonstrating different aspects of joint correlation. Video depicts (1) an efficient reach with elbow extension and (2) inefficient reach with shoulder compensation sound. / This video shows the home-based AMRR Level 1 visual feedback for negative vertical trajectory error. Rocks are depicted to have sunken underwater. / This video shows the home-based AMRR Level 1 visual feedback for a successful lift with an efficient reaching path. The clearance of the fog indicates the portable object was lifted beyond a height threshold. / This video shows the home-based AMRR Level 2 visual feedback for overall path and grasp performance. Video depicts feedback for the following types of overall performance: efficient path, curvature, segmentation, and grasp completion. / This video shows the home-based AMRR Level 3 audiovisual feedback for overall efficiency of a sequence task. Video depicts (1) efficient performance, (2) slightly inefficient performance, and (3) severely inefficient performance. / This video shows the home-based AMRR Level 3 audiovisual feedback for overall efficiency of a transport task. Video depicts (1) efficient performance, (2) slightly inefficient performance, and (3) severely inefficient performance. / This video shows a demonstration of the clinical AMRR system in use with a stroke survivor and supervising therapist. Participant is shown performing interactive reaches to a cone. / Doctoral Dissertation Media Arts and Sciences 2014

Orientador: Dionei Ramos / Banca: Ercy Mara Cipulo Ramos / Banca: Renata Calciolari Rossi e Silva / Resumo: A poluição atmosférica pode afetar negativamente a saúde de quem se exercita ao ar livre, pois durante o exercício físico aeróbico a deposição de partículas nos pulmões é maior em relação ao repouso. A investigação dos efeitos da poluição durante a prática de exercício físico sugeriu que estes indivíduos apresentam maior risco de morbidade respiratória e cardiovascular devido a uma amplificação na absorção respiratória, deposição nos pulmões e toxicidade dos poluentes inalados. Objetivo: Avaliar os efeitos da exposição à poluição atmosférica na cidade de Presidente Prudente - SP sobre a função pulmonar, capacidade funcional, níveis de monóxido de carbono e transportabilidade mucociliar de indivíduos saudáveis praticantes de exercício físico aeróbico em ambiente aberto e fechado. Métodos: Participaram do estudo 24 indivíduos não-tabagistas, entre 40-60 anos, sedentários, randomizados em três grupos: exercício físico em ambiente aberto (Exe-AA), exercício físico em ambiente fechado (Exe-AF) e grupo controle sedentário (GC). Avaliou-se a função pulmonar, a capacidade funcional, o nível de concentração do monóxido de carbono expirado (COex) e o teste do tempo de trânsito da sacarina (TTS). Os poluentes MP10, NO2 e O3 foram quantificados diariamente pela estação automática da CETESB... / Abstract: Air pollution can negatively affect the health of those who exercise outdoors because during aerobic exercise particle deposition in the lungs is higher than rest. The investigation of the effects of pollution during physical exercise suggested that these individuals have a greater risk of respiratory and cardiovascular morbidity due to an amplification in respiratory uptake, lung deposition and toxicity of inhaled pollutants. Objective: To evaluate the effects of exposure to air pollution in the city of Presidente Prudente - SP on pulmonary function , functional capacity, levels of carbon monoxide and mucociliary transportability of healthy individuals who practice aerobic exercise indoor and outdoor environments. Methods: Participated of this study 24 nonsmokers between 40-60 years, sedentary; randomized into three groups: outdoor exercise - (Exe+O), indoor exercise (Exe+In) and sedentary control group (CG). We evaluated pulmonary function, functional capacity, concentration of exhaled carbon monoxide exhaled (exCO) and saccharin transit time test (STT). The PM10, NO2 and O3 were quantified daily by automatic station of CETESB... / Mestre

Orientador: Patrícia Monteiro Seraphim / Banca: Rosa Maria Barilli Nogueira / Banca: Fábio Santos de Lira / Resumo: A literatura aponta que no diabetes mellitus, a expressão gênica de proteínas envolvidas no UPS (ubiquitine-proteasome system) encontra-se acima dos níveis basais, ocasionando degradação de proteínas miofibrilares. Sabe-se que a enzima de conjugação E214kDa e ubiquitina ligase E3 - MuRF1 (Muscle Ring Finger-1) podem ser consideradas como biomarcadores de tal via. Os modelos de animais diabéticos apresentam maior expressão de NFkB (fator nuclear kappa B), o qual tem papel importante na regulação da transcrição do gene do GLUT4. O exercício físico configura-se como método terapêutico no tratamento do diabetes mellitus. A contração muscular melhora a captação de glicose na musculatura esquelética, translocando o GLUT4 via proteína cinase ativada por 5'-AMP (AMPK). Objetivo: Avaliar o efeito de seis semanas de treinamento de salto sobre conteúdo proteico de GLUT4, e expressão gênica (mRNA) dos genes Slc2a4 (proteína GLUT4), UBb (Ubiquitina), E214kDa, Trim63 (proteína MuRF1), NFkB p105 e Prkaa2 (proteína AMPKα2) no músculo gastrocnêmio de ratos diabéticos... / Abstract: The literature suggests that in diabetes mellitus, the gene expression of proteins involved in UPS (ubiquitine - proteasome system) lies above baseline levels, causing degradation of myofibrillar proteins. It is known that E214kDa conjugating enzyme and ubiquitin ligase E3 - MuRF1 (Muscle Ring Finger -1) may be regarded as biomarkers of this pathway. The models of diabetic animals shows increased expression of NFkB (Nuclear Factor kappa B), which plays an important role in the regulation of GLUT4 gene transcription. Exercise appears as a therapeutic method in the treatment of diabetes mellitus. Muscle contraction improves glucose uptake in skeletal muscle GLUT4 translocating protein kinase pathway activated by 5' - AMP (AMPK). Objective: To evaluate the effect of six weeks of jumping on GLUT4 protein content of training, and gene expression (mRNA) of Slc2a4 (GLUT4 protein), UBB (Ubiquitin), E214kDa, Trim63 (MuRF1 protein) , NFkB p105 gene and Prkaa2 (AMPKα2) protein in the gastrocnemius muscle of diabetic rats... / Mestre

Orientador: Vitor Engrácia Valenti / Banca: Luiz Carlos de Abreu / Banca: Nise Ribeiro Marques / Resumo: O objetivo desta dissertação foi analisar os efeitos do exercício com haste oscilatória na recuperação da modulação autonômica cardíaca em mulheres e homens saudáveis. Em buscas realizadas nas principais bases de dados disponíveis não foi encontrado estudo semelhante. O protocolo de exercício consiste em vibrar a haste com ambas as mãos nos planos transversal, paralela ao solo; ombro a 90° de flexão do lado dominante vibrando-a a haste oscilatória no plano sagital perpendicular ao solo; com ombros a aproximadamente 180° de flexão, ambas as mãos seguraram a haste oscilatória vibrando-a no plano frontal, paralelo ao solo. Cada postura foi executada durante três séries de quinze segundos. A VFC Foi analisada 10 minutos antes do exercício e nos momentos pós-exercício: 0-5 minutos, 5-10 minutos, 10-15 minutos. Foram analisados os índices de VFC: SDNN (desvio padrão de todos os intervalos RR normais gravados em um intervalo de tempo), RMSSD (raiz quadrada da média do quadrado das diferenças entre intervalos RR normais adjacentes, em um intervalo de tempo), pNN50 (porcentagem dos intervalos RR adjacentes com diferença de duração maior que 50ms)... / Abstract: The aim of this study was to analyze the effects of exercise with oscillatory pole on cardiac autonomic modulation recovery in healthy women and men. In searches conducted in the main available databases it was not found similar studies. The exercise consisted of vibrating the pole with both hands held the oscillatory pole in the transverse plane, parallel to the ground; shoulder at 90 ° of flexion with the dominant side vibrating to the oscillatory pole in the sagittal plane perpendicular to the ground; shoulders with approximately 180 ° of flexion, both hands held the oscillatory pole vibrating to the frontal plane, parallel to the ground. Each position was performed for three sets of fifteen seconds. HRV was analyzed 10 minutes before exercise and post-exercise time: 0-5 minutes, 5-10 minutes, 10-15 minutes. The HRV indices were analyzed: SDNN (standard deviation of all normal RR intervals recorded in a time interval), RMSSD (square root of the square mean differences between adjacent normal RR intervals in a time interval), pNN50 (percentage of adjacent RR intervals lasting more difference than 50ms)... / Mestre

Orientador: Luiz Carlos Marques Vanderlei / Banca: Carlos Marcelo Pastré / Banca: Francis Lopes Pacagneli / Resumo: Introdução: O treinamento funcional promove benefícios sobre diversas aptidões musculares, entretanto, ainda é desconhecido o seu efeito sobre a modulação autonômica cardíaca, parâmetros cardiorrespiratórios e qualidade de vida em população adulta e saudável. Objetivos: Avaliar a influência de um treinamento funcional sobre a modulação autonômica cardíaca, parâmetros cardiorrespiratórios, força muscular e qualidade de vida em mulheres jovens saudáveis. Métodos: Para sua realização foram avaliados dados de 29 mulheres, as quais foram distribuídas em dois grupos: Grupo Treinamento Funcional (GTF; n = 13; 23 ± 2,51 anos; índice de massa corpórea (IMC) de 21,90 ± 2,82Kg/m²) e Grupo Controle (GC; n = 16; 20,56 ± 1,03 anos; IMC de 22,12 ± 3,86 Kg/m²). O GTF realizou treinamento funcional periodizado por 12 semanas com frequência de 3 vezes na semana, com sessões de 60 minutos de duração. Os dois grupos realizaram as seguintes avaliações antes e após o treinamento: modulação autonômica, parâmetros cardiorrespiratórios, força muscular (teste de 1RM de cada um dos exercícios utilizados no treinamento) e qualidade de vida (Questionário SF-36). Para avaliação da modulação autonômica a frequência cardíaca foi captada batimento a batimento em repouso na posição supina com respiração espontânea por 30 minutos e índices de variabilidade da frequência cardíaca (VFC) foram obtidos nos domínios do tempo e frequência pelo software Kubios HRV... / Abstract: Introduction: Functional training promotes benefits over several muscle skills, however, its still unknown the effect on cardiac autonomic modulation, cardiorespiratory parameters and quality of life in adult healthy population. Objectives: To evaluate the influence of functional training on cardiac autonomic modulation, cardiorespiratory parameters, muscle strength and quality of life in healthy young women. Methods: Data were evaluated from 29 women who were divided in two groups: Functional Training Group (FTG, n = 13, 23 ± 2.51 years, body mass index (BMI) of 21.90 ± 2, 82Kg / m²) and Control Group (CG, n = 16, 20.56 ± 1.03 years, BMI 22.12 ± 3.86 kg / m²). The FTG performed functional training periodization for 12 weeks with a frequency of 3 times a week and a session duration of 60 minutes.Both groups underwent the following assessments before and after training: autonomic modulation, cardiorespiratory parameters, muscle strength (1RM test of each of the exercises used in training) and quality of life (SF-36 questionnaire). For assessment of autonomic cardiac modulation frequency was recorded beat to beat at rest in the supine position with spontaneous breathing for 30 minutes and indexes of heart rate variability (HRV) were obtained in the time and frequency by Kubios HRV software... / Mestre

Orientador: Rúben de Faria Negrão Filho / Coorientador: Rafael Zambelli de Almeida Pinto / Banca: Rômulo Araújo Fernandes / Banca: Vinicius Cunha Oliveira / Resumo: A dor lombar é uma enfermidade extremamente prevalente, afetando grande parte da população em algum momento da vida, no entanto o tratamento da dor lombar até o presente momento tem efeitos pequenos, no máximo, moderados. Um dos fatores geralmente negligenciados nos ensaios clínicos e que podem estar interferindo no tamanho do efeito dos tratamentos é a aliança terapêutica. A aliança terapêutica, pode ser definida como a relação de empatia entre terapeuta e paciente, constituída por três dimensões: vínculos, objetivos e tarefas. Com base nesses domínios foi desenvolvido o questionário Working Alliance Inventory (WAI) como forma de avaliar de forma objetiva a relação terapeuta paciente. Desta forma o propósito foi conduzir um estudo observacional para investigar a capacidade do questionário WAI versão Terapeuta e Paciente, em avaliar a aliança terapêutica em pacientes com dor lombar submetidos ao tratamento fisioterápico. A amostra dos pacientes foi constituída por 100 indivíduos, sendo 54% do sexo feminino. A idade média (desvio-padrão) dos participantes de 47,8(± 15,4) anos e o IMC médio de 27,7(±5,4) kg/m2. A amostra dos terapeutas foi constituída por 18 terapeutas, sendo 77% do sexo feminino com idade média de 25,6 (±4,3) anos. Dados foram coletados em três momentos: após a primeira sessão, antes da segunda sessão e 2 meses após a primeira sessão... / Abstract: Low back pain is an extremely prevalent condition, affecting most of the population at some point in life, however the treatment of low back pain to date have small effects at best moderate. One factor often overlooked in clinical trials that may be interfering with the size of the treatment effect is the therapeutic alliance. The therapeutic alliance can be defined as the relationship of empathy between therapist and patient, consisting of three dimensions: bonds, goals and tasks. Based on these domains the questionnaire Working Alliance Inventory (WAI) was developed as a way to evaluate objectively the therapist patient relationship. Thus the purpose was to conduct an observational study to investigate the ability of the WAI questionnaire therapist and patient version, to evaluate the therapeutic alliance in low back pain patients undergoing physiotherapy treatment. The patient sample consisted of 100 individuals, of whom 54% were female. The (standard deviation) participants' average age of 47.8 (± 15.4) years and mean BMI of 27.7 (± 5.4) kg / m 2. A sample of therapists was consisted of 18 therapists, 77% female with a mean age of 25.6 (± 4.3) years. Data were collected at three times: after the first session, before the second session and two months after the first session... / Mestre

Orientador: Jayme Netto Júnior / Banca: Henrique Luiz Monteiro / Banca: Fábio Yuzo Nakamura / Resumo: Não disponível / Abstract: Background: Metabolic syndrome (MS) is the clustering of risk factors for cardiovascular diseases, such as hyperglycemia, dyslipidemia, increased waist circumference and hypertension. Regular physical activity is an important strategy for the treatment and prevention of metabolic and clinical changes to metabolic syndrome (MS). Resistance training (RT) is a low-cost method that can be used in the treatment and prevention of cardiovascular events. However this method has produced controversial results in relation to the risk factors of MS. Aim: To summarize the effects of resistance training on MS risk factors. Methods: The Medline, PEDro, EMBASE, SPORTDiscus and The Cochrane Library databases were searched from their earliest records to 10 January 2015. Only randomized controlled trials that compared resistance training with a control group were included in this review. The quality and data of the included studies were assessed by two independent reviewers... / Mestre

Made available in DSpace on 2014-06-11T19:22:49Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-12-15Bitstream added on 2014-06-13T19:28:13Z : No. of bitstreams: 1 rodrigues_fmm_me_prud.pdf: 502287 bytes, checksum: 9bce003f664294f683d849f570abca71 (MD5) / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / Introdução: O tabagismo é uma pandemia que causa inúmeros malefícios à saúde, dentre eles estão o aumento da inflamação sistêmica e o prejuízo do transporte mucociliar. Ambos colaboram para o aumento da frequência ou da severidade de infecções respiratórias em indivíduos com e sem doenças pulmonares crônicas tabaco relacionadas. A cessação tabagística é capaz de trazer benefícios, mas não se está bem estabelecido o comportamento dos marcadores inflamatórios nesta condição. Além disso, os efeitos da intensidade tabagística no prejuízo do transporte mucociliar também não foram completamente elucidados. Objetivo: Avaliar o comportamento sistêmico e local de marcadores inflamatórios em 30 dias de abstinência tabagística além dos efeitos das intensidades de consumo tabagístico no transporte mucociliar de tabagistas ativos. Métodos: Foram avaliados tabagistas participantes de um Programa de cessação... / Introduction: Smoking is a pandemic that causes numerous health hazards, including increased systemic inflammation, impaired mucociliary clearance and increased frequency or severity of respiratory infections in individuals with and without chronic lung diseases related to tobacco. Smoking cessation can bring benefits, but is not well established the inflammatory markers' behavior at such condition. Besides that, the effects of the cigarette consumption intensity on impairment of mucociliary clearance have not been fully investigated. Aim: To evaluate the systemic and local behavior of the inflammatory markers at 30 days of smoking abstinence besides the effects of tobacco consumption intensities on mucociliary clearance of active smokers. Methods: We evaluated smokers participating in a smoking cessation program, who were... (Complete abstract click electronic access below)

Made available in DSpace on 2014-06-11T19:22:50Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-02-08Bitstream added on 2014-06-13T20:09:56Z : No. of bitstreams: 1 ferrari_d_me_prud.pdf: 420715 bytes, checksum: 37d1df0ad4202ac6777049d0c05eb4b6 (MD5) / Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) / Apesar da síndrome da dor femoropatelar (SDFP) apresentar alta incidência, sua etiologia permanece obscura e seu diagnóstico clínico e funcional indefinido. Acredita-se que uma das causas da SDFP seja um desequilíbrio entre os músculos vasto medial (VM) e vasto lateral (VL), porém são escassos os estudos que investigam parâmetros eletromiográficos no domínio da frequência destes músculos. Além disso, existe pouca evidência científica em relação à acurácia diagnóstica de testes clínicos e funcionais, assim como da confiabilidade das referências padrão. Portanto, o objetivo é testar a viabilidade de parâmetros eletromiográficos (EMG), do domínio da frequência, para caracterização da SDFP e, posteriormente, utilizá-los como referência padrão para o cálculo da acurácia diagnóstica de um protocolo de avaliação. Foram avaliadas 29 mulheres saudáveis e 22 mulheres portadoras da SDFP. Os sinais eletromiográficos foram obtidos durante o gesto funcional de subida de escada e os músculos analisados foram o VM e o VL. As variáveis eletromiográficas foram submetidas a análises de confiabilidade de medidas, ICC2,k (coeficiente de... / Although patellofemoral pain syndrome (PFPS) exhibit high incidence, etiology remains obscure and it’s clinical and functional undefined. It is believed that one cause of PFPS is an imbalance between the vastus medialis (VM) and vastus lateralis (VL), but there are few studies that investigate electromyographic parameters in the frequency domain these muscles. Moreover, there is little scientific evidence regarding diagnostic accuracy of clinical tests and functional as well as the reliability of the standard references. Therefore, the objective is to test the feasibility of electromyographic parameters (EMG), the frequency domain to characterize the PFPS and then use them as a reference standard to calculate the diagnostic accuracy of an assessment protocol. Were evaluated 29 healthy women and 22 women with PFPS. The signals were obtained during the functional task of stair climbing and the muscles measured were the VM and the VL. The electromyographic variables were subjected to a reliability measures, ICC2, k (intraclass correlation coefficient)... (Complete abstract click electronic access below)

Made available in DSpace on 2014-06-11T19:22:50Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-02-07Bitstream added on 2014-06-13T20:29:12Z : No. of bitstreams: 1 mantovani_am_me_prud.pdf: 364451 bytes, checksum: 11f35032f125a251ca0579b337216de4 (MD5) / Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) / O Pé Diabético, resultante da neuropatia diabética periférica (NDP) associada à vasculopatia diabética periférica (VDP), é a complicação crônica mais frequente e incapacitante do Diabetes Mellitus. Dentre as medidas para prevenir ou melhorar o quadro de complicação dos pés, destaca-se o uso de calçados adequados. Diante disso os objetivos do estudo foram: a) analisar o comportamento dos parâmetros da marcha de não diabéticos e diabéticos com diferentes graus de comprometimento do pé; b) Analisar o comportamento dos parâmetros espaço-temporais e da integral pressão-tempo da marcha de diabéticos neuropatas e vasculopatas em relação ao tempo de uso de um calçado adaptado com palmilha customizada. Para tanto, no primeiro estudo participaram 68 indivíduos de 50 a 65 anos divididos em três grupos: GC - grupo controle (n=33), GN - grupo diabético neuropata (n=18) e GNV - grupo diabético neuropata e vasculopata (n=17). Inicialmente, foram realizados testes para confirmação de NDP e VDP. Em seguida, foram... / The Diabetic Foot, resulting from diabetic peripheral neuropathy (DPN) associated with diabetic peripheral vascular disease (VDP) is the most common chronic complication of Diabetes Mellitus and disabling. Among the means to prevent or improve the complications of the feet, the highlight is the use of appropriate footwear. Thus, the objectives of the study were: a) to analyze the behavior of the gait parameters of diabetic and non-diabetic patients with different degrees of commitment foot b) analyze the behavior of spatiotemporal parameters and pressure-time integral of the gait of diabetics vasculopathies and neuropathies in relation to time use a adapted shoe with custom-made insole. Therefore, the first study enrolled 68 individuals 50-65 years divided into three groups: CG - control group (n = 33), NG - diabetic neuropathy group (n = 18) and NVG - diabetic neuropathy and vasculopata group (n = 17). Initially, tests were performed to confirm the NDP and VDP. Then underwent evaluation by electronic baropodometry in the act of locomotion. The second study consisted of 50 subjects of both genders which were divided into two groups: control group (CG) (n = 33) and diabetic group (DG) (n = 17), with the latter received the footwear with... (Complete abstract click electronic access below)