Thesis (M.S.) -- Mississippi State University. Department of Sociology, Anthropology, and Social Work. / Title from title screen. Includes bibliographical references.

Originally presented as Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 1985. / Includes bibliographical references (p. [178]-218).

Thesis (Ph.D.)--University of British Columbia, 1998. / Includes bibliographical references (leaves 397-446).

Thesis (M. A.)--Trinity Evangelical Divinity School, Deerfield, Ill., 1998. / Abstract. Includes bibliographical references (leaves 152-157).

Thesis (M.A.)--University of North Carolina at Greensboro, 2005. / Title from PDF title page screen. Advisor: Eve Wiederhold; submitted to the Dept. of English. Includes bibliographical references (p. 43-44, p. 96-97).

Thesis (Ph. D.)--University of Texas at Austin, 2005. / Vita. Includes bibliographical references.

<p>Då godsvagnar skall vägas med trådtöjningsgivare monterade i järnvägsräls finns ett antal faktorer som inverkar på mätresultatet. Denna rapport utreder genom datorbaserade simuleringar hur underlag och hastighet inverkar på töjningen i rälsen och även i viss mån hur deformationen i rälsen påverkas. Vidare utreds hur störningar i form av temperaturförändring samt förändring av kontaktkraften mellan vagnshjul och räls inverkar på töjningen. Förändringen av kontaktkraften kan exempelvis bero på hjulplatta, vibrationer från godsvagn eller ojämnheter i rälsen.</p> / <p>When goods wagons are weighed out with a strain gage assembled to a rail there are certain factors that affect the results of the measurement. This report investigates by computer based simulations how the foundation and the speed of a wagon affect the strain and the deformation of a rail. Furthermore, in the report investigations are made how disturbances in the form of changes in temperature and changes of the contact force between the wheel of a wagon and the rail affect strain. The changes can occur due to non-round wheels, vibrations of a wagon or irregular rail.</p>

This thesis focuses on pro-kurdish activism in Turkey during 2005–2009. It is based on a large number of interviews conducted with activists within the Diyarbakır area. The form of activism that this study seeks to describe is civil and political activism conducted within the legal framework ofTurkey’s judicial system and international law.The purpose of this thesis is to examine what kind of resistance strategies are used by pro-Kurdish political activists in Turkey, focusing on how these strategies are reflected in the language used by the respondents. The main question posed in the thesis is: What resistance strategies are used within the pro-Kurdish movement in Turkey? Two additional questions were also posed in order to make it possible to answer the main question. The first of these is: What external conditions influence pro-Kurdish mobilization in Turkey during the study’s time frame? In order to answer this question a theoretical framework is used that includes theories about ethnopolitical mobilization and political opportunity structures. The second question is: What resistance strategies are reflected in the language used by the pro-Kurdish activists?An important resistance strategy used by the pro-Kurdish activists is to adapt the language used in public communication to the legal and political environment in which they find themselves. They make linguistic choices in order to convey political messages while minimizing the legal consequences of doing so. The resistance strategies reflected in the interviews with the activists also include efforts to build organizations and cooperations at different levels, ranging from the international to the local level. Resistance strategies also include choices regarding what medium and language to use in promoting pro-Kurdish politics.

[pt] O câncer constitui patologia de grande importância, visto que já corresponde à segunda maior causa de mortes em todo o mundo, havendo perspectiva de crescimento em número de casos para os próximos anos. Os tratamentos quimioterápicos atuais caracterizam-se por um elevado custo e índice terapêutico relativamente reduzido, estando associados a diversos efeitos colaterais e de resistência do tumor. Diante disso, muitos esforços têm sido direcionados na busca por novas drogas com melhor perfil farmacológico e com atividade frente a linhagens resistentes de tumor, bem como na viabilização de novas vias de administração. Neste sentido, diferentes abordagens têm sido empregadas para o desenho de drogas anticâncer baseadas em metais, como o desenvolvimento de novos complexos análogos à cisplatina, assim como de complexos que se mostrem mais seletivos ao ambiente tumoral. Uma estratégia bastante promissora compreende a preparação de complexos de metais inertes em elevados estados de oxidação, que possam atuar como pró-drogas, atingindo o tumor alvo sem redução prévia nem grandes transformações. Apenas no interior da massa tumoral, devido à condição de hipóxia (baixa oxigenação), normalmente não encontrada em tecidos normais, estes compostos seriam reduzidos, originando então as espécies ativas, que atacariam o alvo mais facilmente. O cobre, por apresentar dois estados de oxidação cujo potencial de redução é acessível dentro da faixa do potencial redox celular, é um elemento promissor. Nesse contexto, foram sintetizados neste trabalho dois complexos de cobre(II) e dois complexos de platina(II) dos ligantes isoméricos 1- e 2-fenil-1,2,3-triazol-4-carboxaldeído-oxima, nunca antes explorados no contexto da Química de Coordenação, sendo que apenas os complexos de cobre poderiam, a princípio, atuar como pró-drogas biorredutíveis. Os complexos foram caracterizados por análise elementar (CHN e AAS), espectroscopia vibracional e termogravimetria. Estudos de EPR no estado sólido foram realizados para os complexos de cobre(II); já os complexos de platina(II) foram também caracterizados por RMN de 195Pt. A modelagem computacional foi utilizada como recurso complementar à proposição estrutural e atribuição das bandas vibracionais dos complexos, com exceção do composto [Cu2(mu-L1)2(HL1)(ClO4)2(OH2)]·2H2O (1), cuja estrutura foi determinada por difração de raios X em monocristal. O outro complexo de cobre(II) é mononuclear: cis-[Cu(HL2)2Cl2] (2). Já os compostos de platina(II) são mononucleares e, como esperado, quadráticos, obedecendo às fórmulas: cis-[Pt(HL1)2Cl2]1 H2O (3) e cis-[Pt(HL2)2Cl2] (4). Os complexos de cobre foram testados nas linhagens de células leucêmicas U937 e THP-1, sendo o complexo 1 e HL1 ainda testados em células normais do sangue do tipo PBMC. Nas linhagens tumorais testadas ambos os complexos reduziram a viabilidade celular de maneira concentração-dependente. O perfil de atividade frente às células U937 foi semelhante para 1 e 2. Entretanto, o composto 1 foi duas vezes mais ativo que 2 contra a linhagem celular THP-1. Cabe ressaltar que 1 foi 23 porcento mais tóxico para a linhagem leucêmica THP-1 do que para as células normais PBMC. HL1 foi capaz de reduzir a viabilidade celular das linhagens tumorais em aproximadamente 30 porcento, não se mostrando tóxico para as PBMC. Os complexos de platina, por sua vez, foram testados na linhagem K562, de leucemia mielóide crônica, tendo ambos demonstrando toxicidade similar e cerca de 5x maior que a droga carboplatina. / [en] Cancer pathology is of great importance, since it is the second leading cause of death worldwide, with a prospect of growth in the number of cases for the next decades. Current chemotherapy treatments are characterized by high cost and a relatively low therapeutic index and are associated with several side effects and tumor resistance. Therefore, many efforts have been focused on the search for new drugs with an improved pharmacological profile and tumor-resistant lineage activity, as well as the feasibility of new administration routes. In this regard, different approaches have been employed for the design of metal-based anticancer drugs, such as the development of new cisplatin analogue complexes, as well as complexes that may be more selective to the tumor environment. A very promising strategy involves the preparation of high oxidation state inert metal complexes, which may act as prodrugs, reaching the tumor target without prior reduction or significant transformations. Only inside the tumor mass, due to hypoxia conditions (low oxygen) not normally found in normal tissues, these compounds would be reduced, originating the active species which would then attack the target more easily. Copper, by presenting two oxidation states whose reduction potential is accessible within the range of the cellular redox potential, is a promising element. In this context, two copper(II) complexes and two platinum(II) complexes with the isomeric ligands 1- and 2-phenyl-1,2,3-triazole-4-carboxaldehyde oxime were synthesized in the present study, which have never before been explored in the context of Coordination Chemistry, with only the copper complexes, in theory, demonstrating the potential to act as bioreductive prodrugs. The complexes were characterized by elemental analysis (CHN and AAS), vibrational spectroscopy and thermogravimetry. EPR studies in solid state were performed for the copper(II) complexes, while the platinum(II) complexes were also characterized by 195Pt NMR. Computer modeling was used as a complementary resource for structural propositions and assignment of the vibrational bands of the complexes, with the exception of coordination compound [Cu2(mu-L1)2(HL1)(ClO4)2(OH2)]·2H2O (1), whose structure was determined by single crystal X-ray diffraction. The other mononuclear copper(II) complex is cis-[Cu(HL2)2Cl2] (2). On the other hand, the platinum(II) compounds are mononuclear and as expected, quadratic, according to the formulae cis-[Pt(HL1)2Cl2]1 H2O (3) and cis-[Pt(HL2)2Cl2] (4). The copper complexes were tested against the leukemic cell lines U937 and THP-1, with complex 1 and HL1 also being tested on normal PBMC blood cells. Both complexes reduced cell viability in a concentration-dependent manner in the tested tumor lines; The activity profile towards U937 cells was similar for 1 and 2. However, compound 1 was twice as active as 2 against cell line THP-1. It is worth noting that 1 was 23 percent more toxic against the leukemic cell line THP-1 when compared to normal PBMC cells. The platinum complexes, alternatively, were tested against the K562 cell line, chronic myeloid leukemia, and both demonstrated similar toxicity, approximately 5x higher than carboplatin.

Background: Due to accelerating environmental problems caused by fast fashion sustainable business solutions become increasingly important. Thus, the following thesis examines generation y’s intention to perform in-store recycling at fast fashion retailers and investigates the factors most influential on intention. Besides, it analyses if an attitude-intention gap exists. To fulfil the study’s purpose, a combination of the theory of planned behaviour (Ajzen, 1985) and the norm activation model (Schwartz, 1977) is used.   Approach: Within this study a quantitative method in terms of an online survey is applied. Based on a sample of 326 respondents, relationships between variables are analysed with Pearson correlation analysis and multiple regression. To further identify differences among groups, Independent samples t-test and ANOVA are conducted.     Findings: The study’s findings reveal that generation y generally intends to participate in in-store recycling, while the intention is significantly higher among women than men. The intention to perform in-store recycling is predominantly intrinsically motivated as it is most driven by individuals’ personal norm.    Value: The findings of our study particularly add value for fast fashion retailers and marketers by presenting a novel research model combining most relevant factors required to adequately address consumers among generation y to perform in-store recycling. This specifically allows fashion retailers to successfully establish the concept of in-store recycling. Our study is further beneficial for sustainability researchers, environmental activists, charity organisations and policy makers to create a more sustainable future.