This work is concerned with the implementation and implication of non-volatile charge storage on VLSI system design. To that end, the floating-gate pFET (fg-pFET) is considered in the context of large-scale arrays. The programming of the element in an efficient and predictable way is essential to the implementation of these systems, and is thus explored. The overhead of the control circuitry for the fg-pFET, a key scalability issue, is examined. A light-weight, trend-accurate model is absolutely necessary for VLSI system design and simulation, and is also provided. Finally, several reconfigurable and reprogrammable systems that were built are discussed.