The diploma thesis deals with the problems of pavement surface skid resistence of wearing course of asphalt mixtures with R-material. Specifically, it is a mixture of type ACO 11 (asphalt concrete for wearing layers). In the theoretical part of the thesis there are dismantled the problems of Antiskid properties of the road surface and recycling of R-material. The practical part is dedicated to the design and laboratory production of the asphalt mixture ACO 11 without admixture of R-material and with content of 38 % R-material. In addition, the results of the measurement of friction coefficient after smoothed for these bitumen mixtures are shown in the work. The aim of the thesis was to determine the influence of the increased content of R-material on the anti-skid properties of the road surface as it is planned to update the standard ČSN EN 13108-1, which will allow the use of up to 40 % R-material into the mixtures of type ACO 11.

This diploma thesis deals with a project of asphalt mixtures with high stiffness modulus using R-material. The theoretical part describes the characteristics of these mixtures in the Czech Republic and in Switzerland. Further this part deals with the use of R-material in the Czech Republic and chosen other countries of the world, it also deals with the ways of recycling roads. The theoretical part also deals with the testing methods used. In the practical part two new asphalt mixtures of the high stiffness modulus type with the addition of 25 % R-material are suggested. As a base for these two mixtures a mixture of the high stiffness modulus type, which was taken from an asphalt mixing plant, was used. Tests were run on the binders and several functional tests (stiffness modulus, fatigue resistance, low temperature qualities) wer done on the suggested asphalt mixtures and also the mixture taken from the mixing plant. Consequently, the results were compared. The conclusion of the thesis is devoted to modelling a construction of a road using the program LayEps, which verified if the suggested mixtures could reduce the thickness of roads.

This thesis is focused on creation of mobilization curves, based on data, obtained from standard and detailed monitoring of the load test. The load test was performed on the 9 meters long ductile micropile. The first part of the thesis explains the methods and principles, which was used to construct the mobilization curves. Next there is description of the technologies of ductile micropiles and the load test. In the next part of the thesis is generally explained process, which was applied to the evaluated data. For evaluation was used spreadsheet Microsoft Excel and programming language Matlab, with Kernel Smoothing extension. In the last chapter of the thesis there are interpreted the load transfer function together with skin friction and micropile displacement.

The master thesis consists of a theoretical part and a practical part. In the theoretical part jet-grouting technology is described briefly. Mechanical properties of jet-grouted piles were characterized. Various estimation methods of ultimate pile bearing capacity are described in this thesis – analytical calculation of ultimate bearing capacity for bored piles and estimation of ultimate pile bearing capacity by analysis of load-displacement curve defined by CHIN (1970; 1972). Load transfer method for piles and hyperbolic load-transfer curve are introduced. As a part of the load-trasfer method analysis, a method of estimating ultimate pile shaft friction called beta method is defined. In the practical part were evaluated several static load tests of jet-grouted piles and were constructed their load-displacemnt curves. Then reverse analysis of the results from static load tests was performed using load-transfer method. Then ultimate pile bearing capacity was estimated using analytical calculation of pile bearing capacity for bored piles and using analysis of load-displacement curve with method by CHIN (1970; 1972). By evaluation of load transfer method and beta method ultimate shaft resistence for each pile was estimated. Results and load-displacement curves were compared.

This thesis examines the magnetic field and magnetic flow at the end of the stator synchronous machine. This problem is solid using nonlinear magnetic resistive network, which is simulating by PSpice software. A simple model of stator, consisting of stator plates, air gaps and the two-thumbs, which hold the stator together. All of this is replace magnetic nonlinear resistive network, which is then divided into elements. According to these element is a simplified model solid and analyzed.

This thesis deals with the analysis of the car driving characteristics depending on the type of drive wheels. The first chapter defines the basic theoretical cars concept as well as procedures for determining the individual variables needed to identify the driving dynamics of vehicles. The practical part describes the plan and the progress of realized measurements on a selected pattern of vehicles, and the measured values are interpreted. The final part deals with the evaluation of the performed measurements and the data identified within these measurements.

The theoretical part of the thesis deals with the hydraulics of heating systems. The aim of the project is a design of the heating and hot water preparation system for an apartment building. The building has 6 above-ground floors and 2 underground floors. Two different options of heating systems were designed, comparison and results are presented in the thesis. In the first case the heat source during the winter season and for water heating, where chosen two gas condensing boilers, situated in separated room on the second underground floor. In the second case, each apartment has its own gas condensing boiler. The experimental part of the project deals with measurements of pressure losses in water armatures used in heating systems. The aim of this part is the determination of coefficients of added resistance for uncontrolled elements, which are normally presented as tabular value. In thesis are presented results for a ball valve, backflow preventer, filter, for slide valve and thermostatic valve. Measurements for thermostatic valve where done with different settings and results are compared with parameters listed in the datasheet.

The goal of this dissertation is to describe an evolution of visions of the Slovak future, as they were introduced during the Great War (1914-1918) by groups of Slovaks living mainly abroad. It strives to decide, which of these visions had a chance to become real and which were only fantasies without real political importance. To reach this goal it tries to describe Slovak relations to other relevant nations in pre-war years and also the position of Slovaks in their fatherland or abroad including the ideologies by which they were influenced. One of most decisive goals of this dissertation should be answering the question if the Czecho-Slovak orientation was the only alternative to the idea of Hungarian state for Slovak politicians, or if the victory of this conception in 1918 was just a result of unpredictable processes, and whether other conceptions had their chance to influence the Slovak future, too.

The aim of this master thesis is to summarize the overview about characteristics and properties of timber and about diagnostic methods used for timber structures prospecting. Experimental part is focused on comparison of drill resistance measurement using Rinntech RESISTOGRAPH for samples at different moisture levels. This paper also includes building survey of roof truss of Litomyšl‘s library and structural report of rafter.

In animals, some of the most critical regulators of gene expression are nuclear hormone receptors (NRs) and their coregulators, specifically the Mediator complex. Of particular interest are the NRs implicated in metabolic and developmental regulation and in carcinogenesis: thyroid hormone receptors (TRs) and retinoid X receptors (RXRs). In this work, I venture to elucidate some aspects of gene expression regulation by these NRs: the degree of evolutionary conservation of signalling based on NRs and their coregulators; the mechanisms of negative regulation by NRs; and possible implications of these findings for clinical medicine. State-of-the-art bioinformatical, genome editing and microscopic techniques are applied at three levels of animal evolution to study NRs and Mediator. Reverse genomics in human patients suffering from the syndrome of resistance to thyroid hormones β are used to infer the structure and function of TRβ subdomains. Alignments, binding studies and in vivo experiments in Trichoplax adhaerens allow identification of a close orthologue of human RXR at the basis of metazoan evolution. Employing database queries, genome editing and microscopy, we describe a correct orthologue of the Mediator subunit 28 in Caenorhabditis elegans, indicating a complete homology of the Mediator complex...