v anglickém jazyce The purpose of the thesis is a cultural heritage management of the small baroque sacral buildings, which has passed unnoticed for a longer period of time. As a model region is chosen the district Ceska Lipa. First, in this thesis is briefly summarized the history of district Ceska Lipa since the 18th century. Then the thesis describes various factors which have had an influence on the local monuments. Particularly the regional factors which are responsible for the heritage damage and also the conditions and institutions participating in the heritage preservation and documentation. Next, the overview of typology and terminology of a small sacral architecture is also covered. The major part of this thesis is a catalogue of explored monuments in different villages or small towns including the village/ town history and the art historic establishment of the monuments. This part is also focused on the documentation and comments of the current preservation of each building. The recommendation of preservation is proposed herein as a potential way of monument restoration. Finally, the research outcomes are discussed with regard to a possible management and future exploring.

The topic of this diploma thesis is design processing of a new sacral building in Brno-Líšeň district. It is a plot in the middle of a panel building between the health centre building and the building of the Salesian Youth Center, so-called Salesko. The Salesian community, which will use the building the most, has been waiting for the realization of this building for many years. The key theme is the creation of spaces enabling people to meet for worship, celebrations and social events. The design is processed by two interconnected operations - the building of the Church of the Descent of the Holy Spirit and the building of clergy house. The basic composition consists of three cubic masses - the entrance, the main liturgical space and the clergy house. The bell tower is the height dominant feature which indicates the sacral function of the building. The project consists a set of buildings with two above-ground floors and a basement in the entrance part of the church. This project also mentions the solution of open spaces around the plot and their conversion into quality public areas, marginally. The sacral space is to become a place that welcomes and takes in its visitors and gives them the feeling of safety. Inside this building, people will find peace, support and undestarstanding, so they may leave with the feeling of being a better person.

Le syndrome de l’intestin irritable (SII) et le syndrome de la vessiedouloureuse (SVD) sont tous deux caractérisés par une hypersensibilité viscérale àla distension. Sur le plan épidémiologique, ces deux syndromes sont étroitementassociés puisque les patients SII ont une prévalence du syndrome de la vessiedouloureuse 7 fois plus élevée que la population générale. Cependant, le mécanismeresponsable de la sensibilisation du tube digestif et de l’appareil urinaire n’a jamaisété étudié. Compte tenu de l’innervation commune de ces deux organes, il estprobable que ce mécanisme mette en jeu sur le long terme des phénomènes de laplasticité neuro-gliale aux niveaux communs d’intégration de la sensibilité pelvienne.L’objectif général de ce travail était d’établir et de caractériser un modèleanimal de sensibilisation croisée vessie/colon, aigu et chronique, afin de mieuxcomprendre les mécanismes impliqués dans l’hypersensibilité viscérale croisée. / Irritable bowel syndrome (IBS) and Bladder pain syndrome (BPS) are bothcharacterized by visceral hypersensitivity to distension. Epidemiology showed thatthese two syndromes are closely associated since IBS patients have a prevalence ofbladder pain syndrome that is 7 times higher than the general population. However,the mechanism responsible for sensitization of the gastrointestinal tract and theurinary tract has never been studied. Given the common innervation of these twoorgans, it is likely that this mechanism involves long-term phenomena of neuro-glialplasticity at the common levels of integration of pelvic sensitivity.The overall objective of this work was to establish and characterize an animalmodel of bladder / colon cross-sensitization, acute and chronic, to better understandthe mechanisms involved in cross-visceral hypersensitivity.

The thesis deals with European sacral architecture of the twentieth and the twenty-first century. Particularly, it refers to Judaic, Roman-Catholic and Islamic buildings. The second part puts into historical context the sacral constructions of individual religions including their function, characters and typology. In the third part of this thesis the representative sample of significant modern sacral constructions is selected, always under circumstances regarding their creation, the urban description and the setting in a specific location as well as the architectural layout, the interior arrangment and a possible use of special technological procedures at their construction. The mutual comparison and the evaluation of the modern European sacral architecture development are carried out in the fourth part. This section notices the function and the usage of light and presents some extraordinary buildings from this point of view. The final fifth part tries to answer the question, how a modern temple should look like.