The development of the concept of irreverence is examined in terms of its historical, theoretical and metatheoretical contexts. The underlying assumptions of the concepts of neutrality, curiosity, and irreverence are distinguished and contextualised. Neutrality is discussed with reference to Milan systemic therapy and first- and second-order cybernetics, while curiosity is examined in the light of constructivist and narrative approaches to psychotherapy. It is argued that these two concepts represent two sides of a dualism, which is transcended through irreverence. Irreverence is interpreted as a postmodern stance, involving the questioning and relativising of therapists' basic assumptions. The pragmatic components of an irreverent stance, namely self-reflexivity, orthogonality, flexibility and accountability, are explored with reference to related concepts in the work of other authors. Throughout the text metalogues are used in an attempt to engage reader and author in a collaborative enterprise of acknowledging and reevaluating their own basic assumptions. / Psychology / M.A. (Clinical Psychology)

Made available in DSpace on 2014-12-17T15:42:05Z (GMT). No. of bitstreams: 1 AnaLPFC.pdf: 1922699 bytes, checksum: c82e91dbc8eb0d49eecb97284bc06938 (MD5) Previous issue date: 2009-08-14 / Due to its physico-chemical and biological properties, related to the abundance and low cost of raw material, chitosan has been recognized as a material of wide application in various fields, such as in drug delivery systems. Many of these properties are associated with the presence of amino groups in its polymer chain. A proper determination of these amino groups is very important, in order to properly specify if a given chitosan sample can be used in a particular application. Thus, in this work, initially, a comparison between the determination of the deacetylation degree by conductometry and elemental analysis was carried out using a detailed analysis of error propagation. It was shown that the conductometric analysis resulted in a simple and safe method for the determining the degree of deacetylation of chitosan. Subsequently, experiments were performed to monitor and characterize the adsorption of tetracycline on chitosan particles through kinetic and equilibrium studies. The main models of kinetics and adsorption isotherms, widely used to describe the adsorption on wastewater treatment systems and the drug loading, were used to treat the experimental data. Firstly, it was shown that an apparent linear t/q(t) ? t relationship did not imply in a pseudo-second-order adsorption kinetics, differently of what has been repeatedly reported in the literature. It was found that this misinterpretation can be avoided by using non-linear regression. Finally, the adsorption of tetracycline on chitosan particles was analyzed using insights obtained from theoretical analysis, and the parameters generated were used to analyze the kinetics of adsorption, the isotherm of adsorption and to ropose a mechanism of adsorption / Devido ?s suas propriedades f?sico-qu?micas e biol?gicas, associadas ? abund?ncia e ao baixo custo da mat?ria-prima, a quitosana tem sido considerada um material de ampla aplica??o em diversos campos, tais como em sistemas de libera??o de f?rmacos. Muitas dessas propriedades est?o associadas ? presen?a de grupos amino em sua cadeia polim?rica. Uma determina??o apropriada desses grupos amino ? muito importante, com o objetivo de especificar adequadamente se uma dada amostra de quitosana pode ser usada em uma particular aplica??o. Dessa forma, neste trabalho, inicialmente, foi realizada uma compara??o entre a determina??o do grau m?dio de desacetila??o atrav?s de an?lises condutim?trica e elementar usando uma minuciosa an?lise de propaga??o erro. Foi mostrado que a an?lise condutim?trica resultou em um m?todo simples e seguro para determina??o do grau m?dio de desacetila??o da quitosana. Posteriormente, foram realizados experimentos a fim de monitorar e caracterizar o processo de adsor??o de tetraciclina em part?culas de quitosana, atrav?s de estudos cin?ticos e de equil?brio. Os principais modelos cin?ticos e de isotermas de adsor??o, amplamente usados para descrever a adsor??o em sistemas de tratamento de efluentes e de incorpora??o de f?rmacos, foram utilizados nos dados experimentais. Primeiramente, foi mostrado que uma aparente rela??o linear t/q(t) ? t n?o implica em um mecanismo de adsor??o de pseudo-segunda-ordem, diferentemente do que tem sido repetitivamente relatado na literatura. Foi encontrado que esta interpreta??o err?nea pode ser evitada atrav?s do uso de uma regress?o n?o-linear. Finalmente, a adsor??o de tetraciclina em part?culas de quitosana foi analisada, utilizando os conhecimentos obtidos de uma an?lise te?rica, e os par?metros gerados foram usados para analisar a cin?tica de adsor??o, a isoterma de adsor??o e para propor um mecanismo de adsor??o

The development of the concept of irreverence is examined in terms of its historical, theoretical and metatheoretical contexts. The underlying assumptions of the concepts of neutrality, curiosity, and irreverence are distinguished and contextualised. Neutrality is discussed with reference to Milan systemic therapy and first- and second-order cybernetics, while curiosity is examined in the light of constructivist and narrative approaches to psychotherapy. It is argued that these two concepts represent two sides of a dualism, which is transcended through irreverence. Irreverence is interpreted as a postmodern stance, involving the questioning and relativising of therapists' basic assumptions. The pragmatic components of an irreverent stance, namely self-reflexivity, orthogonality, flexibility and accountability, are explored with reference to related concepts in the work of other authors. Throughout the text metalogues are used in an attempt to engage reader and author in a collaborative enterprise of acknowledging and reevaluating their own basic assumptions. / Psychology / M.A. (Clinical Psychology)