abstract: This dissertation examines how violent fantasizing influences the behavior of a brutal sub-class of murderers--mass and serial killers. Specifically, fantasy gives the perpetrator a profane catharsis due to his or her inability to cope with reality. The researcher identified, four common fantasy scripts: (Revenge Fantasy; Sexual, Sadistic and Misogynistic Fantasy; Suicidal-Homicidal Ideation; and Search for Validation through Infamy and Media Attention Fantasy) that more or less, play into the motivations and actions of mass and serial killers. Thus, it is important to understand why and how the killer moves from an all-consuming imaginative space to actually harming others. The methodology used for this research was "ethnographic content analysis" and, to a lesser extent, empirical phenomenology and semiotics. Source materials that were analyzed included: artifacts generated by the offenders prior to commission of their crimes (e.g., diaries, manifestos, blogs, drawings, photographs, and videotapes); official findings of governmental review panels; other public documents; survivor, witness or family accounts; news reports; and work conducted previously by other academics. This dissertation is particularly novel, in that the role of fantasy has not received much critical analysis with respect to mass murder. Likewise, the researcher's examination of current theory on the ontogenesis of moral dysfunction led to an original interpretation in the works of criminologists, Eric Hickey and Lonnie Athens. From a synthesis of Hickey's trauma-control theory and Athens' esoteric constructs of "self" and "other" a more cohesive understanding of the homicidal personality emerged. Essentially, the researcher argues that the intersection of early derailing influences and pervasive life losses result in a fragmented concept of self, which the now deeply unstable individual seeks to validate through violent fantasy and homicidal acts. It is further proposed that these findings may lead to future inquiry into: methods for early intervention and diversion of an at-risk population; and where the foregoing is impractical, better methods of detecting, mitigating the harm caused by and quickly apprehending these particularly violent offenders. / Dissertation/Thesis / M.S. Justice Studies 2011

The phenomenon of serial murder has fascinated people for many years. Despite this fascination, the body of scientific knowledge surrounding this topic seems quire limited. Research is often based on second-hand and anecdotal sources of information and not on direct contact with the individuals who commit these crimes. Based on this information, assumptions are made about these individual’s mental state and personality. This research which was undertaken is unique in that it is an in-depth look at two individuals who committed serial murder. The research design, grounded in interactional theory, makes use of unstructured interviews, an interactional analysis, and psychological tests such as the South African Wechsler Adult Intelligence Scale, Thematic Apperception Test, Millon Clinical Multiaxial Inventory IIIed, Minnesota Multiphasic Personality Inventory 2nd Edition, and 16 Personality Factor Questionnaire in an attempt to try and come to a psychological understanding and interactional description of these two individuals’ behaviour. In doing so it revisits what has already been said about this phenomenon, makes comparisons, and provides a brief theoretical view of the phenomenon as part of man’s social order. / Thesis (PhD (Psychology))--University of Pretoria, 2007. / Psychology / unrestricted

It was hypothesised that there would be behavioural consistencies in the offences of South African serial killers. The themes underlying these observable differences can help us understand the nature of these offences. Crime scene data was ohtained from police records, and structured, in-depth offender interviews. 73 offences, committed by 13 offenders, were analysed. The analysis used Smallest Space Analysis (SSA), a Multidimensional scaling (MDS) procedure. This analysis revealed systematic patterns of behaviour in the offences. It was found that the focus of these offences is an impersonal, hostile, and act-focused murder were the victim is treated as a depersonalised object. Empirical support for an underlying thematic structure to these offences was also provided. The offence themes identified relate to the nature of the actions committed during the offence, and the function these actions had for the offender. These fmdings thus support the hypothesis that these offences will display meaningful behavioural variation. These findings have direct utility in the investigation and study of serial killing in South Aflica. They also provide the basis for comparison with previously suggested typologies of serial killing, and indicate directions for future research into this phenomenon in the South African setting. / KMBT_363 / Adobe Acrobat 9.54 Paper Capture Plug-in

Objective: To describe the changes in plasma glucose concentration in severely injured, canine to canine bite wound cases admitted for veterinary treatment. The changes were measured over a period of 72 hours from the initiation of the trauma. Historical, signalment, clinical and haematological factors were investigated to determine their possible relationship to blood glucose concentration. Hypo- and hyperglycaemia have been associated with death from sepsis and acute injury. Method: Twenty dogs admitted to the Intensive Care Unit at Onderstepoort Veterinary Academic Hospital (OVAH) with severe bite wounds were evaluated. The time of injury was established by questioning the dogs’ owners. Blood was taken on admission for haematology and plasma glucose concentration. Haematology was repeated every 24 hours and glucose every 8 hours, measured from the time the dogs were first bitten. Results: On admission, 5% (1/20) of the dogs were hypoglycaemic, 40% (8/20) were normoglycaemic and 55% (11/20) were hyperglycaemic. No other dogs showed hypoglycaemia during the study period. The median glucose at each of the ten collection points, prior to the 56-hour collection point and at the 72 hour collection point, was in the hyperglycaemic range (5.8mmol/l to 6.2mmol/l). Puppies and thin dogs had considerably higher median plasma glucose concentrations than adult and fat dogs at 0 and 16 hours respectively (P < 0.05 for both). A high incidence of SIRS was encountered (65% to 80%). Fifteen dogs were alive at 72-hours. Thirteen dogs (81.3%) eventually made a full recovery. Three out of four dogs (75%) that were recumbent on admission, died, whereas all dogs (12/12) admitted with either an alert or depressed mental status survived (P = 0. 004). Clinical significance: The high incidence of hyperglycaemia may be explained by the ‘diabetes of injury’ phenomenon. The role of insulin therapy in the treatment of severe injuries should be explored in future studies, as its use in the treatment of human ICU cases, has resulted in a substantial reduction of fatalities resulting from acute injury. The high incidence of death and initial hyperglycemia in the collapsed group and the higher plasma glucose concentrations found in puppies and thin dogs warrants further investigation with a larger group of animals. / Dissertation (MMedVet (Small Animal Surgery))--University of Pretoria, 2007. / Companion Animal Clinical Studies / MMedVet / unrestricted

The research aimed to explore the phenomenon of serial murder from a systems theory perspective. The purpose of the study was to develop an understanding of serial murder in a South African context from a family systems approach. Utilizing a family systems theoretical framework and the genogram method, the study, which was qualitative in nature, explored information about the family systems of individuals who committed serial murder via content analysis. The investigation focused mainly on emotional processes, multigenerational and relationship patterns in family systems. Information was gathered from numerous sources and included interviews conducted inter alia with individuals currently incarcerated for serial murder and their family members, and with professionals involved with such individuals; as well as information obtained from clinical observations and archival data. The results of the content analysis demonstrated considerable similarities but also differences in the organization and functioning of the family systems of individuals who committed serial murder. Importantly, the analysis shed novel theoretical light on the role of serial murder within family systems and challenged established dominant theoretical perspectives on serial murder that have emphasized linear, causal and/or individual-focused explanations. The study opened up considerable opportunities for further exploration of the phenomenon from a systemic perspective, specifically with the focus on the meaning of serial murder in relatively smaller (e.g., parent-child or peer relationships) or larger (e.g., political, cultural and societal) systems. It also provided opportunities for alternative vistas from which the phenomenon of serial murder can be viewed in terms of theoretical, definitional, typological, investigative and correctional approaches. / Thesis (PhD (Psychology))--University of Pretoria, 2006. / Psychology / unrestricted

Programmed Cell death (PCD) is a highly conserved and genetically controlled event that plays important roles in animal development, homeostasis and disease. Our first objective was to discover and characterize new genes involved in PCD. Since many PCD genes are conserved in Drosophila, and steroid-induced PCD of larval salivary glands (SGs) is transcriptionally regulated with features of both apoptosis and autophagy, we used this exceptionally well-suited in vivo system and performed Serial Analysis of Gene Expression (SAGE) in three pre-death stages. SAGE identified 1244 expressed transcripts, including genes involved in autophagy, apoptosis, immunity, cytoskeleton remodeling, and proteolysis. Of the 1244 transcripts, 463 transcripts belonged to knownlpredicted genes and were 5-fold differentially expressed prior to cell death. Next, we investigated the role of differentially expressed genes from SAGE, in cell death or cell survival, by RNA interference (RNAi ) in l(2)mbn haemocyte Drosophila cells. l(2)mbn cells undergo morphological changes in response to ecdysone treatment, and ultimately undergo PCD. We used cell viability, cell morphology, and apoptosis assays to identify the death-related genes and determined their ecdysone dependency and function in cell death regulation. Our RNAi screen identified six new pro-death related genes, including SH3PXJ and Soxl4, and 21 new pro-survival genes including SoxN. Identification of Soxl4 as pro-death and SoxN as pro-survival suggests that these Sox box proteins may have opposing roles in ecdysone-mediated cell death. Our final objective was to elucidate the function of CG409], a Drosophila homologue of human TNF-alpha induced proteins 8 (TNFAIP8) we identified from SAGE. We created loss-of-function and overexpression mutants of CG4091 to study gene function in vivo and employed immunoprecipitation and mass-spectrometry assays to identify proteins interacting with CG409] in vitro. We identified two proteins that are involved in n-fatty acid oxidation and several cytoskeletal proteins as interaction partners. Immunofluorescence based assays in vivo and in vitro revealed that CG409] is necessary for cytoskeletal remodeling. Further, defects in CG4091 expression affect cellular functions such as autophagy and lipid metabolism/trafficking that require an intact cytoskeleton. Together, our studies provided new insights into the molecular mechanisms involved in Drosophila SG cell death. / Medicine, Faculty of / Medical Genetics, Department of / Graduate

The effects of sex and tutorial instruction were studied as they influenced the seriation ability of pre-school children. The research was conducted at the Utah State University Child Development Laboratories with 24 four year old children enrolled at that time. Twelve of the children, six girls and six boys, were given seriation tasks. The remaining 12 children, six girls and six boys, were not given any seriation training. It was found that the 12 children who had received individualized instruction seriated significantly better on every task than the 12 children who had received no training. The children who were trained in seriation tasks also correctly transferred their learning of seriation from the original set of objects used in the training sessions to two other sets of size graded objects. The remaining 12 children did not make this transfer as successfully. There was no significant difference in the seriation ability of boys and girls, although the girls receiving training improved more than the boys who were trained in seriation. This finding was attributed to the fact that the boys in both groups seriated slightly higher than t.he girls in both groups; therefore the boys who received no seriation training did not have as much room for improvement.

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No description available.

The present project aimed to characterize the role of serial order within the working memory and language domains by first addressing a) whether serial order processing is domain-general and then b) whether serial order processing underlies vocabulary acquisition. Experiment 1 revealed that order memory in the visuo-spatial domain is qualitatively similar to order memory for verbal memoranda by reporting visuo-spatial equivalents of two well-known effects in verbal STM for serial order, repetition inhibition (e.g., Crowder, 1968) and repetition facilitation (Crowder, 1968). The effects were, however, accompanied by critical differences that may be due to modality-specific processes. Experiment 2 directly investigated whether verbal and visuo-spatial STM rely on common ordering mechanisms using a delayed recall dual-task design that contrasted two types of visuo-spatial interference tasks during a concurrent verbal serial order memory task (digit sequence memory). The visuo-spatial tasks probed either serial order STM or non-serial order (item) STM. Serial-order specific interference effects with the concurrent verbal serial order STM task were found. In experiment 3, we replicated the investigations of Experiment 2 using a word-learning paradigm as a concurrent task in place of the verbal serial order STM task that was previously used. Again interference by a visuo-spatial STM task was found only when it required memory for serial order. In sum, the results suggest that verbal and visuo-spatial STM subsystems rely on common mechanisms for serial order processing. These in turn appear to communicate with domain-specific processing substrates involved in item-level memory representations. Furthermore, the results indicate that such domain-general serial ordering mechanisms are also involved in novel word-learning. Taken together, the present findings provide crucial constraints for modeling of order representations. They also offer insight into mechanisms shared by vocabulary acquisition and STM tasks. / Thesis / Doctor of Philosophy (PhD)