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<p>Allocation concealment is the process of implementing the randomization sequence in a manner that prevents foreknowledge of upcoming group assignments. It protects against preferential enrolment of study participants, which could disrupt the prognostic balance that randomization aims to create in the first place. Envelopes are one method perceived by clinical trial authorities to adequately conceal allocation, despite evidence suggesting otherwise. We do not believe that envelopes are adequate, and we wanted to know the extent to which our sentiment resonated within the clinical trials community. We administered an internet-based survey to a random sample (n=1,926) of corresponding authors of recently published randomized clinical trials (RCTs). We sent non-responders up to two e-mail reminders starting from two weeks after the original invitation. We received 490 complete surveys (25.4% response rate) after collecting data for seven weeks. Most participants (61%) preferred central randomization to conceal allocation, yet a majority (64%) also accepted that envelopes are adequate. After they were shown examples that suggested envelopes’ vulnerability, 11% of participants shifted their preference away from envelopes and 38% of participants became less accepting of envelopes. Compared to their initial ratings and after they were shown the examples, significantly more participants (69%) preferred central randomization (p</p> / Master of Science (MSc)

Recent public health scholarship finds that health outcomes are explained by the social and individual determinants of health rather than the individual-level determinants alone. The individualistic perspective has dominated the 20th century institutionalization of public health in the United States where the public health system has tended to focus largely, if not exclusively, on individual factors. This persistent orientation lies in contrast to another set of perspectives that have also persisted, focused on social causes, which are currently dominant in contemporary public health academic literature and in major, international health organizations. Whether the orientation within the United States is due to a prevailing paradigm among public health officials or is the result of new ideas about health causation being dampened under organizational weight is unknown. Despite public health being central to decreasing morbidity and mortality in the 20th century, significant gaps remain in researchers' understanding of what influences practice in the American public health system. My dissertation research investigates the broad outlines of the determinants of health as understood by state public health administrators. I study how the understanding of the determinants of health affects the practice of public health through analyzing how the ideas of state public health administrators interact with the organizational dynamics of the public health organizations they lead. This mixed-methods dissertation uses survey research and in-depth interviews and quantitative and qualitative analysis. I find that state public health officials' professionalization, length of tenure, level of education, and gender affect the perspective of health causation to which they adhere. I also find that the state public health officials with a social health frame more commonly report they are situated in organizations that are learning environments. Both organizational and ideational factors influence public health practice. The interview data expand this finding to paint a complex picture of organizational and ideational factors influencing one another as well as resulting practices. This research reveals that state public health officials often have strong health frames that are only able to shape the edges of their practice due to the political and organizational dynamics interacting with state public health departments. / Ph. D.

Implementing Lean in the United States transportation equipment manufacturing industry holds the promise for improvements in, among other things, productivity, quality, and innovation, resulting in more competitive success and profits. Although Lean has been applied throughout the industry with noted success, there have been some difficulties in demonstrating the financial benefits derived from Lean initiatives. Most of the evidence supporting a positive relationship between Lean implementation and improved financial performance is anecdotal. As companies have become more proficient in carrying out Lean initiatives in manufacturing, they have extended Lean ideas to other parts of their organization and throughout the entire supply chain. Nowadays, it is widely recognized that a holistic, enterprise-wide view is critical to obtain the potential benefits of a Lean transformation. However, Lean transformations are often undertaken without consideration of supporting functions such as accounting and finance. Lean transformation in accounting and finance should be run in the same way as it is in the manufacturing environment by decreasing reporting cycle time, improving transaction processing accuracy, eliminating unnecessary transaction processing, changing product costing procedures, and financial reporting among many other things, but there is limited empirical evidence of that happening. To address these shortcomings, this research focuses on three areas. First, this study aims to evaluate transportation equipment manufacturing facilities in respect to their operational and financial performance. Second, this study aims to investigate the extent of Lean implementation of a given operation in respect to leadership, manufacturing, accounting and finance, and supplier and customer relationship and correlate these results to their performance. Finally, this study aims to further examine the contextual characteristics of companies that successfully aligned their systems with Lean. A mixed-mode survey, addressed to a subset of the United States transportation equipment manufacturing industry, asked questions pertinent to companies' Lean transformation efforts, performance, and general characteristics. During the four months long survey period, a total of 69 valid responses were received, for a response rate of 3.78 percent. From the 69 valid responses, 8 responses were eliminated due to containing more than 20 percent missing values. Multiple imputation procedure was applied to handle remaining missing values in the dataset. Before testing study hypotheses, scale reliability and construct validity tests were run to decide whether a particular survey item should be retained in further analysis. Study hypotheses were then tested using profile deviation analysis, multiple regression analysis, and hierarchical regression analysis. When the level of Lean implementation and performance relationship was investigated using a multiple regression analysis, results did not show any evidence that the higher level of Lean implementation along four business dimensions (leadership, manufacturing, accounting and finance, and supplier and customer relationship) of transportation equipment manufacturing facilities positively influences their operational and financial performance. However, it was revealed that the higher level of Lean implementation in transportation equipment manufacturing facilities' manufacturing dimension resulted in better quality performance as measured by first-time through, inbound quality, and outbound quality. When the same relationship was investigated using a profile deviation analysis, results were identical. When the level of Lean implementation in accounting and finance and its relationship with performance was investigated using a single regression analysis, results showed that the higher level of Lean implementation in transportation equipment manufacturing facilities' accounting and finance dimension has a positive effect on accounting performance and on operational performance (e.g., on time-based performance and delivery-based performance), but no effect on financial performance. When the same relationship was investigated using a profile deviation analysis, results were different by showing no relationship between the level of Lean implementation in transportation equipment manufacturing facilities' accounting and finance dimension and accounting, operational, and financial performance. Lastly, the effect of contextual variables (e.g., industry segment, location, annual sales volume, and unionization) on performance, the level of Lean implementation, and the performance -- Lean implementation relationship was investigated using hierarchical regression. Results showed that transportation equipment manufacturing facilities' performance is influenced by annual sales volume. Their level of Lean implementation in the accounting and finance dimension is influenced by location, while their performance -- Lean implementation in the accounting and finance dimension relationship is influenced by industry segment. / Ph. D.

Since the early 2000s, Interactive Voice Response (IVR) has become a widely popular method of conducting public opinion surveys in the United States. IVR surveys use an automated computer voice to ask survey questions and elicit responses in place of a live interviewer. Previous studies have shown that IVR polls conducted immediately before elections are generally accurate, but have raised questions as to their validity in other contexts. This study examines whether IVR polls generate measurably different levels of candidate support when compared to live interviewer polls, as a result of non-response bias owing to lower response rates in IVR surveys. It did so by comparing polling in 2010 U.S. gubernatorial and U.S. Senate elections that was conducted using both live interviewers and IVR. The findings suggest that in general elections, IVR polls find fewer undecided voters compared to surveys conducted using live interviewers. In primary elections, IVR polls can show larger support than live interview polls for a more ideologically extreme candidate who has high levels of support among more opinionated and engaged voters. Implications are that journalists and other consumers of polling data should take into account whether a poll was conducted using IVR or live interviewers when interpreting results. IVR polls may tend to over-sample more engaged and opinionated voters, often resulting in smaller percentages of undecided respondents, and higher levels of support for specific candidates in certain contexts. / Master of Arts

Objective: The aims of our present study were to develop a valid and reliable survey framed around the social cognitive theory, which would evaluate internal and external factors associated with food insecurity from the student's perspective, and to test the survey with a multi-state population. Design: The College Perspectives around Food Insecurity (CPFI) survey was developed through several revision and improvement steps using a mixed methods approach. In Phase 1 (2018-2019), data were translated into survey items and assigned to a theoretical concept (personal, behavioral, or environmental) in the social cognitive theory. In Phase 2 (2019-2020), content validity testing occurred through two rounds of expert reviews. In Phase 3 (2021), researchers conducted two rounds of cognitive interviews with college students to evaluate face validity. In Phase 4 (2022), the survey underwent stability and internal consistency reliability testing. Participants: Three expert reviewers evaluated the initial survey draft during Phase 2. Participants for Phases 3 and 4 were college students at least 18 years old. Analysis: Descriptive statistics (means and frequencies) were used for expert reviewer scores, timing data, and demographics. Researchers used test-retest and Cronbach's alpha to measure survey reliability. Results: The initial survey contained 143 items: 54 personal, 52 behavioral and 37 environmental. After several testing and revision steps the final survey contained 95 items: 40 personal, 26 behavioral, and 29 environmental. Test/retest reliability was 0.989 and Cronbach's alpha scores were 0.47 for personal, 0.39 for behavioral, and 0.74 for environmental. Mean length of time to complete the full survey was 16.38 min (SD=8.88 min). Conclusions and Implications: The CPFI survey can be used to better understand internal and external factors associated with food insecurity in college students which could inform interventions aimed at assisting this population.