BACKGROUND:Nephropathic cystinosis is an autosomal recessive disease resulting from intracellular accumulation of cystine leading to multiple organ failure.CASE REPORT:We describe the clinical course of a patient managed from the age of six until his death at the age of 33 years. He underwent multiple surgery, including two renal transplants, developed transplant renal artery stenosis that was managed medically, and progressive heart failure at the age of 33 years. His death from a ruptured pseudoaneurysm associated with a restrictive cardiomyopathy is noteworthy. A limited cardiac autopsy revealed the presence of cystine crystals in interstitial cardiac histiocytes and one myocardial cell, along with 1000-fold higher tissue cystine content of the left ventricular myocardium compared to patients without cystinosis, suggesting the possibility of direct cystine mediated metabolic injury.

The aim of this study was twofold. First, to explore what challenges social workers may experience in their work with female rape survivors. The second aim was to explore how social workers work with females who have survived rape. A qualitative research design was chosen, and semi-structured interviews with social workers were conducted. Thematic analysis was used to structure the findings. Four themes were found in connection to challenges; feelings of shame and guilt among rape survivors, the criminal proceedings, to not be able to help all survivors and lastly potential threats to social workers’ own wellbeing. The findings regarding methods were that the social workers adapt their work strategies based on the needs of the survivor. The social workers used strategies focused on reducing feelings of shame and guilt and normalizing symptoms.

Research report presented to the Unisa School of Business Leadership / The purpose of the research is an investigation into how employee involvement can be used as a tool towards raising levels of engagement within actively disengaged employees at Ngwane Mills.

The academic study of rape has historically ignored the recovery experience of the person being raped. Beyond medical and physical effects, and the possibility of legal prosecution, little attention has been paid. Existing research loses sight of the survivor's experience, ignoring the fact that a rape affects every aspect of life. The trauma is not only physical, but also impinges on the emotional, intellectual and interpersonal spheres. Rape can be, and often is, a life-threatening experience: one that needs to be faced and dealt with before there can be any sort of productive future. While it has been demonstrated that rape strips away a sense of safety and well-being, very little work has addressed how this can be regained, especially from feminist perspectives. A rape renders every aspect of identity subject to destruction and must be renegotiated and rebuilt if one is to survive. Survivor is the right term-there is no other word to describe it. The feminist canon has struggled for decades to open a discourse into the division between the sexes, critiquing the notion that masculinity equals aggression and proclaiming the falsity of the notion that men are genetically programmed to dominate. Despite this, stereotypes remain. In part because of this, feminist researchers and theorists who address the topic of rape have been preoccupied with increasing public education and awareness. Women's perspectives of rape have been neglected. The act of identity renegotiation involves three steps: understanding the event, accepting the trauma, and recovering one's identity by adapting what was to define what is. As feminist thought recognizes that there is no one definitive characteristic meant by "woman", this project by no means claims to include every survivor's path, but instead offers an overview of what might be involved. What I hope to accomplish through this project is illustrating how the process of renegotiation crosses into every sphere of identity: that is emotional, intellectual, physical, spiritual and psycho-social.

The main objective of this dissertation is to present the structural design, performance evaluation, and complexity reduction of iterative joint channel estimation and data detection receivers. One of the main technical challenges in advanced wireless communications stems from the characteristics of a wireless channel, e.g., time selectivity of a channel, mobility of users, and multipath propagation. Channel estimation is essential for achieving reliable information transmission for practical wireless communication applications. Numerous channel estimation structures have been developed for different underlying channels using pilot-symbol assisted modulation (PSAM) approaches. However, since pilot symbols carry no data information, the time and the power spent on pilot symbols degrades the efficiency and the throughput of the system. Therefore, it is necessary to minimize the pilot insertion ratio without degrading the error performance. This motivates our research on iterative joint channel estimation and data detection receivers with full- and reduced- or low-complexity. In this thesis, we first propose an iterative channel estimator (ICE), based on a maximum a posteriori (MAP) algorithm, for single-carrier systems with PSAM structures. In contrast to existing MAP channel estimators, the proposed channel estimator has a lower computational complexity, which increases linearly with the modulation alphabet size. The computational complexity is reduced by exploiting a survivor in an efficient manner, while achieving comparable error performance to a full complexity receiver. For orthogonal frequency division multiplexing (OFDM) systems, we also propose novel signal constellations to facilitate channel estimation without pilot symbol transmission, and analyze the bit error rate for the proposed constellations. We also develop a suitable joint channel estimation and data detector with full- and low-complexity for the proposed constellations. This low-complexity ICE achieves an error performance comparable to the ICE with full-complexity. Finally, for vertical Bell Laboratories layered space-time OFDM systems, we propose an ICE based on a PSAM structure for time-varying multipath fading channels. By exploiting the statistical properties of a wireless channel, we also develop a method to suppress intercarrier interference due to the channel time selectivity, and propose a low-complexity ICE that exploits a priori information in an efficient manner.

Recently, organization downsizing has become the major means used by corporations to seek survival or better growth. Organization downsizing has some purposes: to reduce the cost of personal, to get better efficiency, to rearrange the deployment of human resource after M&A. Besides those economic purposes, some scholar think corporations do organization downsizing to get legitimacy. Generally speaking, the purpose of organization downsizing is to get better efficiency or the legitimacy. But lots of researches indicate lots of organization downsizing can not achieve expected goals. Although some corporations can achieve the goal of organization downsizing, many corporations can¡¦t achieve expected goals, and there are also some corporations do a lot of organization downsizing but their situations go from bed to worse. Among the researches of why organization downsizing can¡¦t achieve expected goals, many researches indicate that the application of organization downsizing will make huge negative impact to survivors. Some scholars call that impact survivor syndrome. Besides, some scholars investigate the reason of the failure of organization downsizing from the point of informal social network. Because the theory of social capital includes trust, organization involvement, social network and so on, we can more understand the reason of the failure of organization downsizing from the point of social capital. So the purpose of this research is to use the theory of social capital to investigate the impact of organization downsizing and provide some advices to corporations, so that they can do better about organization downsizing. This research uses case study to understand the reason and the process of organization downsizing, and investigates the negative impact of organization downsizing. Survivor syndrome and social capital play important roles in the analysis of the failure of organization downsizing. This research finds that organization downsizing will do huge damage to social capital. If corporation don¡¦t understand the importance and benefit of social network, then the application of organization downsizing will hurt social network and corporations can¡¦t achieve expected goals. Besides, in the analysis of case study this research finds that organization downsizing also hurt trust, involvement, incentives to cooperation and so on, these issues are part of survivor syndrome, but we also can use social capital to explain.

Recent research shows that cancer survivors are at greater risk of developing cancer than the general population. Knowledge of the magnitude of second cancer risk and cancer-specific deaths among cancer survivors, factors that influence their second cancer risk, cancer survivors’ perceptions of second cancer risk and current practices and existing gaps in follow-up care is urgently needed if we hope to prepare survivors and their healthcare providers as to how best to monitor their long-term health. An exploratory mixed method study, guided by Kaplan and colleagues (2000) multilevel approach to the health determinants, was conducted to provide a detailed understanding of second cancer risks among cancer survivors. Data collection methods included: (1) qualitative survey of current practices in the follow-up care offered for cancer survivors across Canada, (2) population-based health databases (cancer registry and health insurance databases), and (3) qualitative interviews on cancer survivors’ perceptions of second cancer risks. Coordinated follow-up services are not universally available across Canada. Yet, cancer survivors have a 4-7-fold increased risk of developing cancer compared to the general population in Nova Scotia and Manitoba. Second cancer risks varied by demographic and disease-related factors such as age at first cancer diagnosis, cancer type, treatment era, and time since diagnosis. Second cancer risk does not exist only as an epidemiological calculation. Second cancer risk, from the perspective of cancer survivors, is shaped by more intuitive conceptual models than statistical models of risk. The theme, Life After Cancer – Living with Risk, described survivors’ sense that second cancer risk is now a part of their everyday lives.

Recent research shows that cancer survivors are at greater risk of developing cancer than the general population. Knowledge of the magnitude of second cancer risk and cancer-specific deaths among cancer survivors, factors that influence their second cancer risk, cancer survivors’ perceptions of second cancer risk and current practices and existing gaps in follow-up care is urgently needed if we hope to prepare survivors and their healthcare providers as to how best to monitor their long-term health. An exploratory mixed method study, guided by Kaplan and colleagues (2000) multilevel approach to the health determinants, was conducted to provide a detailed understanding of second cancer risks among cancer survivors. Data collection methods included: (1) qualitative survey of current practices in the follow-up care offered for cancer survivors across Canada, (2) population-based health databases (cancer registry and health insurance databases), and (3) qualitative interviews on cancer survivors’ perceptions of second cancer risks. Coordinated follow-up services are not universally available across Canada. Yet, cancer survivors have a 4-7-fold increased risk of developing cancer compared to the general population in Nova Scotia and Manitoba. Second cancer risks varied by demographic and disease-related factors such as age at first cancer diagnosis, cancer type, treatment era, and time since diagnosis. Second cancer risk does not exist only as an epidemiological calculation. Second cancer risk, from the perspective of cancer survivors, is shaped by more intuitive conceptual models than statistical models of risk. The theme, Life After Cancer – Living with Risk, described survivors’ sense that second cancer risk is now a part of their everyday lives.

abstract: The bereaved and those who have experienced trauma have received support through music therapy. However, there has been no research on the effectiveness of music therapy as a therapeutic intervention for those who have experienced the loss of a loved one by suicide. While every loss presents its own challenges, those who experience a suicide loss may need extra support to process the traumatic nature of the death. This study aims to explore the current research on grief and trauma to determine what information can be applied to the care of those who have experienced a suicide loss. The present study is a group case study of survivors of suicide who have experienced a loss within the last 3 years. Participants received weekly music therapy sessions for four weeks. All participants completed the Inventory of Traumatic Grief, prior to and at the conclusion of the music therapy sessions, and the pre and post test scores were compared. Additionally qualitative data was collected throughout the sessions, indicating any common themes that emerged throughout the sessions and the participants’ reactions to the interventions, as well as in a short questionnaire following the four sessions. / Dissertation/Thesis / Masters Thesis Music Therapy 2016

Masters of Commerce / Organizations are operating within a difficult economic environment and in the face of fierce world competition (George & Jones, 1992 cited in Ndlovu & Brijball Parumasur, 2005). To remain competitive globally and for economic reasons, Theron and Dodd (2011) postulate that organizations sporadically have to retrench workers. In order to reduce expenses as well as costs and losses to the organization, they have to restructure and reduce their headcount and the typical form of engaging in the restructuring is by means of downsizing. Makawatsakul and Kleiner (2003) posit that employee morale and loyalty tend to be the first unintended casualties of a downsizing strategy. The repercussions of downsizing is that it jeopardizes employees’ commitment and morale to a large extent (Muthuvuloo 8Rose, 2005) and survivors thus experience lower job and organizational satisfaction (Baruch & Hind, 2000) as this creates insecurity, anxiety and uncertainty. Survivors are also often forced to make a sideway or downward move in their job, may experience a drop in pay and status, become stressed by the amount of work left by departing colleagues that they would now need to undertake and worry about the security of their new position in the organization (Chipunza & Berry 2010). In light of the above, the aim of the study was to investigate the organizational commitment of those employees who survived and remained with the retail organization following a downsizing process. For the purpose of this study a quantitative, non probability convenience sampling design was utilized. The sample (N=150) comprised of both males and females from different ethnic groups. A self developed biographical questionnaire and the Organizational Commitment Questionnaire (OCQ) were used to gather data. Statistical analyses involved both descriptive and inferential statistics (the Pearson Product-Moment Correlation Coefficient, Multiple Regression Analysis and Analysis of Variance). The results of the study indicate that employees display below average levels of commitment to the organization. More specifically, a direct, positive relationship was found between normative and affective commitment. Furthermore, a statistically significant relationship was found between affective and continuance commitment. Statistically significant relationships were found between the biographical characteristics namely, tenure, gender and age, and organizational commitment. Limitations of the current study are put forth and recommendations are made with respect to future research and for the organization.