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Previous issue date: 2012-08-23 / Introduction : Major depression is one of the most relevant mental disorders in elderly. Some authors propose that the distinction between cases of early-onset and late-onset major depression is justified by differences in etiology, clinical picture and comorbidities. Such differences are still not clarified enough, and some disagreement among studies does exist. Objectives : To investigate the distinctive characteristics between elderly with early-onset and late-onset major depression with respect to sociodemographic factors, self-perceived health, cardiovascular risk factors, cognitive deficit, family history of depression, depressive symptoms, melancholic features, suicide risk and alcohol abuse/dependence. Methods : Cross-sectional, descriptive and analytic study, with prospective data collection, in an aleatory sample of 348 elderly (≥60 years old) of the Health Family Strategy, of which were identified 90 cases of DSM-IV unipolar major depression; subjects were divided according to early or late (≥60) age at onset of depression. Results : The prevalence of major depression in the whole sample was 25,86%. Depressive subjects were mainly of early-onset (69,14%) and of female sex (74,4%); the mean age in years was higher in the late-onset major depression group (p= 0,028); the groups did not differ with respect to the other evaluated factors; after multivariate analysis there was a trend toward a negative association between suicide risk and late-onset depression. Conclusion : The early or late age at onset of depressive symptoms was not associated with distinctive profiles, neither with respect to clinical picture, nor with respect to the risk factors. The results of this paper give support to the hypothesis that early and late-onset major depressive disorders are clinically undistinguishable and do not represent distinct pathologies or subtypes. / Introdu??o : A depress?o maior ? um dos transtornos mentais mais relevantes em idosos. Alguns autores prop?em que a distin??o entre casos de depress?o maior de in?cio precoce e de in?cio tardio ? justificada por diferen?as na etiologia, quadro cl?nico e comorbidades. Tais diferen?as ainda n?o est?o bem esclarecidas, havendo discord?ncias entre os estudos. Objetivos : Investigar as caracter?sticas distintivas entre idosos com depress?o maior de in?cio precoce e de in?cio tardio quanto a fatores sociodemogr?ficos, autopercep??o de sa?de, fatores de risco cardiovascular, d?ficit cognitivo, hist?ria familiar de depress?o, sintomas depressivos, caracter?sticas melanc?licas, risco de suic?dio e abuso/depend?ncia de ?lcool. M?todos : Estudo transversal descritivo e anal?tico, de coleta prospectiva, em uma amostra aleat?ria de 348 idosos (≥60 anos de idade) da Estrat?gia Sa?de da Fam?lia, dos quais foram identificados 90 casos de depress?o maior segundo crit?rios do DSM-IV; os sujeitos foram divididos de acordo com a idade de in?cio precoce ou tardia (≥60 anos) da depress?o. Resultados : A preval?ncia de depress?o maior na amostra total foi de 25,86%. Sujeitos deprimidos na maioria dos casos foram do grupo de in?cio precoce (69,14%) e pertencentes ao sexo feminino (74,4%); a m?dia de idade em anos foi maior para o grupo com depress?o maior de in?cio tardio (p= 0,028); os grupos n?o diferiram quanto aos demais fatores avaliados; ap?s an?lise multivariada, houve uma tend?ncia de associa??o negativa entre risco de suic?dio e depress?o de in?cio tardio. Conclus?o : A idade de in?cio precoce ou tardio dos sintomas depressivos n?o esteve associada a perfis distintos, nem quanto ao quadro cl?nico, nem quanto a fatores de risco. Os resultados deste trabalho d?o suporte ? hip?tese de que a depress?o maior de in?cio precoce e a de in?cio tardio s?o indistingu?veis clinicamente e n?o representam patologias ou subtipos distintos.
| Identifer | oai:union.ndltd.org:IBICT/oai:tede2.pucrs.br:tede/2682 |
| Date | 23 August 2012 |
| Creators | Ulrich, Luiz Eduardo Flores |
| Contributors | Cataldo Neto, Alfredo |
| Publisher | Pontif?cia Universidade Cat?lica do Rio Grande do Sul, Programa de P?s-Gradua??o em Gerontologia Biom?dica, PUCRS, BR, Instituto de Geriatria e Gerontologia |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Format | application/pdf |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da PUC_RS, instname:Pontifícia Universidade Católica do Rio Grande do Sul, instacron:PUC_RS |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 4438661476953179033, 500, 600, 2296420844541114010 |
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