Monitoring an individual’s mobility with a modern smartphone can have a profound impact on rehabilitation in the community. The thesis objective was to develop and evaluate a third-generation Wearable Mobility Monitoring System (WMMS) that uses features from inertial measurement units to categorize activities and determine user changes-of-state in daily living environments. A custom suite of MATLAB® software tools were developed to assess the previous WMMS iteration and aid in third-generation WMMS algorithm construction and evaluation. A rotation matrix was developed to orient smartphone accelerometer components to any three-dimensional reference, to improve accelerometer-based activity identification. A quaternion-based rotation matrix was constructed from an axis-angle pair, produced via algebraic manipulations of acceleration components in the device’s body-fixed reference frame. The third-generation WMMS (WMMS3) evaluation was performed on fifteen able-bodied participants. A BlackBerry Z10 smartphone was placed at a participant’s pelvis, and the device was corrected in orientation. Acceleration due to gravity and applied linear acceleration signals on a BlackBerry Z10 were then used to calculate features that classify activity states through a decision tree classifier. The software tools were then used for offline data manipulation, feature generation, and activity state prediction. Three prediction sets were conducted. The first set considered a “phone orientation independent” mobility assessment of a person’s mobile state. The second set differentiated immobility as sit, stand, or lie. The third prediction set added walking, climbing stairs, and small standing movements classification. Sensitivities, specificities and -Scores for activity categorization and changes-of-state were calculated. The mobile versus immobile prediction set had a sensitivity of 93% and specificity of 97%, while the second prediction set had a sensitivity of 86% and specificity of 97%. For the third prediction set, the sensitivity and specificity decreased to 84% and 95% respectively, which still represented an increase from 56% and 88% found in the previous WMMS. The third-generation WMMS algorithm was shown to perform better than the previous version in both categorization and change-of-state determination, and can be used for rehabilitation purposes where mobility monitoring is required.

AdaBoost has been considered one of the best classifiers ever developed, but two important problems have not yet been addressed. The first is the dependency on the ``weak" learner, and the second is the failure to maintain the performance of learners with small error rates (i.e. ``strong" learners). To solve the first problem, this work proposes using a different learner in each iteration - known as AdaBoost Dynamic (AD) - thereby ensuring that the performance of the algorithm is almost equal to that of the best ``weak" learner executed with AdaBoost.M1. The work then further modifies the procedure to vary the learner in each iteration, in order to locate the learner with the smallest error rate in its training data. This is done using the same weight calculation as in the original AdaBoost; this version is known as AdaBoost Dynamic with Exponential Loss (AB-EL). The results were poor, because AdaBoost does not perform well with strong learners, so, in this sense, the work confirmed previous works' results. To determine how to improve the performance, the weight calculation is modified to use the sigmoid function with algorithm output being the derivative of the same sigmoid function, rather than the logistic regression weight calculation originally used by AdaBoost; this version is known as AdaBoost Dynamic with Logistic Loss (AB-DL). This work presents the convergence proof that binomial weight calculation works, and that this approach improves the results for the strong learner, both theoretically and empirically. AB-DL also has some disadvantages, like the search for the ``best" classifier and that this search reduces the diversity among the classifiers. In order to attack these issues, another algorithm is proposed that combines AD ``weak" leaner execution policy with a small modification of AB-DL's weight calculation, called AdaBoost Dynamic with Added Cost (AD-AC). AD-AC also has a theoretical upper bound error, and the algorithm offers a small accuracy improvement when compared with AB-DL, and traditional AdaBoost approaches. Lastly, this work also adapts AD-AC's weight calculation approach to deal with data stream problem, where classifiers must deal with very large data sets (in the order of millions of instances), and limited memory availability.

This exploratory study investigates how racialized immigrant women experience and respond to intimate partner abuse (IPA). The American and European models of intersectionality theory are used to highlight structural constraints and agentic responses as experienced and enacted by racialized immigrant women. Eight women described their experiences through semi-structured interviews, revealing an array of both defensive and pro-active types of strategies aimed at short- and long-term outcomes. Responses included aversion, negative reinforcement or coping strategies like prayer or self-coaching, and accordingly varied by the constraints under which the women lived as newcomers to Canada. Policy recommendations promote acknowledgement of women’s decision-making abilities and provide a model in which women can choose from a selection of options in how to respond, rather than strictly interventionist models. Study results can help to challenge stereotypes of abused women as passive victims, and empower the image of immigrant women as active knowers of their circumstances.

Hydrocarbons are an abundant resource of carbon and hydrogen. For example, fossil can be used to produce useful organic compounds. However hydrocarbons seem to be inert. Thus, the activation of the C-H bond is a popular research area. Metals play the main role in most catalysts that convert hydrocarbons to starting materials in industry. The study of metals is important because the properties of the metal core greatly influences the reactivity of a catalyst.1 The study of the chemistry of metals in the gas phase provides valuable information about the properties of metals. This information can be expanded to the chemistry of metals in the condensed phase. Furthermore, it is often both more accurate and more manageable to study the profile of a reaction in the gas phase than in the condensed phase.2,3 There are many studies about metal cations in the gas phase due to ease of their production. However metals have low electronegativity, limiting the study of gas phase metal anions. Recently, a simple and efficient method to generate atomic metal anions was developed at the University of Ottawa in Dr. Mayer's research laboratory.4-6 Atomic metal anions of Fe-, Co-, Cu-, Ag-, Cs- and K- were generated in an electrospray ionization (ESI) source of a mass spectrometer (MS). In this thesis study generated metal anions were reacted with small hydrocarbons of pentane, 1-pentene, 2-pentene and 1-pentyne to investigate the role of different metal anions in the activation of the C-H bond. Also metal anions were reacted with small alcohols of 1-butanol, 2-butanol and 2-methyl-2-propanol to compare the results. Metal anions showed a variety of reactions with these hydrocarbons and alcohols. Fe- was the only metal anion to show the electron transfer reaction, indicating that alcohols are more electronegative than Fe- and less electronegative than other metal anions. Fe-, Co- and Ag- showed the complex formation reaction. All metal anions showed the deprotonation reaction. A deprotonation reaction follows the harpoon mechanism, the long range proton abstraction7, and depends on the gas phase acidity of fragments. The most informative reaction observed was the dehydrogenation reaction because a metal-containing fragment is observed as a product in the spectrum of this reaction. The observation of a metal-containing fragment in the spectrum is significant because it emphasizes the important role that metal anions play in this reaction. This suggests that a dehydrogenation reaction involves metal insertion into a C-H bond. Among the transition metal anions, it was observed that Fe- and Cu- are more reactive than Co- and Ag- with regards to the dehydrogenation reaction, probably because Fe- and Cu- have a greater hydrogen affinity than Co- and Ag- that facilitates the hydrogen abstraction reaction. Another reason could be that Fe- and Cu- have a greater gas phase acidity that leads to a more stable intermediate in the course of the reaction. The results of this thesis study revealed that Cs- and K- could not abstract H from these substrates, probably due to the absence of occupied d orbitals that would facilitate insertion into a C-H bond. Some metal anions not only can insert into a C-H bond of alcohols but also can insert into a C-O bond of alcohols to form metal hydroxide anions. Alcohols are more reactive than hydrocarbons with regards to reactions with metal anions because they contain a functional group. This thesis study shows that some atomic metal anions are able to activate the C-H bond and abstract two hydrogens to form a double bond in hydrocarbons. It is probable that the electronic configuration, gas phase acidity and hydrogen affinity of the metal anions governs their reactivity.

Despite growing interest in coaching sciences, literature has revealed a dearth of research on coaches who work with para athletes (e. g. Cregan, Bloom, & Reid, 2007; McMaster, Culver, & Werthner, 2012). The purpose of this study was to explore how novice coaches in parasport develop their knowledge. The study was conducted in real-time during the coaches’ first contact with the context. Semi-structured interviews and participant observation were conducted with six Canadian para sailing coaches. Thematic analysis (Braun & Clarke, 2006) revealed that coaches developed context-specific knowledge and skills through a blend of formal, nonformal, and informal learning situations. The participants highlighted the importance of learning from others, especially other coaches and from athletes.

My thesis explores the conceptual underpinnings of the acclaimed Mexican conditional cash transfer (CCT) program Oportunidades as a way of engaging broader debates about how anti-poverty policy is evolving in the wake of the World Bank’s mid-1990s legitimacy crisis. I am interested in the behaviours and attitudes—or “subjectivities”—that Oportunidades attempts to cultivate amongst participants. Whereas the majority of CCT studies tend to focus on measuring the extent to which the programs “mold” beneficiaries into the categories of being prescribed by the program, my thesis is concerned with specifying and critically examining these categories. I use a hybrid neo-Gramscian, governmentality and critical feminist theoretical framework to probe how Oportunidades beneficiaries are constructed within World Bank and Mexican government discourse, as well as in external program evaluations. I argue that Oportunidades is underpinned by an agent-centred conception of poverty and that the program promotes a kind of gendered market-conducive subjectivity amongst beneficiaries. I conclude by exploring some of the implications of the CCT model. Ma thèse explore les fondements conceptuels du Oportunidades, un programme de transferts conditionnels de fonds (TMC) Mexicain acclamé. J’utilise les TMC comme une ouverture pour élargir le débat sur la manière dont la politique anti-pauvreté évolue dans le sillage de la crise de légitimité à laquelle la Banque Mondiale a fait face dans le milieu des années 1990. Je m'intéresse aux types de comportements et d'attitudes—ou «subjectivités»—que Oportunidades essaye de cultiver chez les participants. Alors que la majorité des études sur les TMC focalisent sur l’évaluation des succès du programme à modeler les participants afin qu’ils entrent dans les catégories de personnes prescrites par le programme, mon but est la spécification et l'examen critique de ces catégories. J'utilise un cadre théorique hybride qui combine néo-gramsciennes, la gouvernementalité et des théories féministes critiques pour enquêter sur la façon dont les bénéficiaires du programme Oportunidades sont construits à l’intérieur du discours de la Banque Mondiale, du gouvernement mexicain, ainsi que dans les évaluations externes du programme. Je soutiens qu’il y a, dans le programme Oportunidades, une conception sous-entendu de la pauvreté centrée sur les comportements des individus et que le programme promeut une subjectivité sexuée des bénéficiaires qui facilite leur participation au marché. Je conclus en explorant quelques implications du modèle TMC.

Feminist activism has a rich history in Canada, but mobilization on the issue of violence against women specifically gained considerable momentum during what is often referred to as the “second wave” of the feminist movement. Since this time, the Canadian provinces of Ontario and Quebec have seen a proliferation of both grassroots and public policy responses to intimate partner violence and sexual violence. This study is an effort to construct a feminist history of the activism that occurred between 1970 and 2010, as well as to make sense of feminist claims-making strategies using a social constructionist approach to social problems and to make sense of feminist activism as a social movement using social movement impact theory. In constructing a feminist history, documents from the Canadian Women’s Movement Archives were consulted and interviews with current and former feminist activists were conducted. The historical component of this study focuses on how feminist activists first recognized and responded to the problem of violence against women. This analysis suggests that throughout the last forty years, feminist activists have engaged in a multi-pronged project of providing feminist services for victims of intimate partner and sexual violence, advocating for social and legal change as the “official” response to violence against women, and conducting their own research on the extent and nature of violence against women. Various strategies were used in this process, including forming partnerships and coalitions, but activists also faced challenges from within and outside the movement, including internal debates, struggles to fit in, and backlash from counter movements. The final chapter discusses how the history of feminist activism on violence against woman cannot easily fit into strict constructionist approach to understanding social problems and, as a social movement, is difficult to evaluate given the myriad goals, mechanisms for reaching those goals, and interpretations of success associated with the movement. Future research directions are also suggested, including looking at evidence of claims-making from other sources; bridging the gap, theoretically and pragmatically, between the “mainstream” feminist movement and other streams of women’s activism; and, more conceptual work on feminist movements and the separation between intimate partner and sexual violence.

The current understanding of lactate metabolism in fish is based almost entirely on interpretation of concentration measurements that cannot be used to infer changes in flux. Moreover, the transporters regulating these fluxes have never been characterized in rainbow trout. My goals were: (1) to quantify lactate fluxes in rainbow trout under normoxic resting conditions, during acute hypoxia, and exercise by continuous infusion of [U-14C] lactate; (2) to determine lactate uptake capacity of trout tissues by infusing exogenous lactate in fish rest and during graded exercise, and (3) to clone monocarboxylate transporters (MCTs) and determine the effects of exhausting exercise on their expression. Such information could prove important to understand the mechanisms underlying the classic “lactate retention” seen in trout white muscle after intense exercise. In normoxic resting fish, the rates of appearance (Ra) and disappearance (Rd) of lactate were always matched (~18 to 13 µmol kg-1 min-1), thereby maintaining a low baseline blood lactate concentration (~0.8 mM). In hypoxic fish, Ra lactate increased from baseline to 36.5 µmol kg-1 min-1, and was accompanied by an unexpected 52% increase in Rd reaching 30.3 µmol kg-1 min-1, accounting for a rise in blood lactate to 8.9 mM. In exercising fish, lactate flux was stimulated > 2.4 body lengths per second (BL s-1). As the fish reached critical swimming speed (Ucrit), Ra lactate was more stimulated (+67% to 40.4 μmol kg-1 min-1) than Rd (+41% to 34.7 μmol kg-1 min-1), causing an increase in blood lactate to 5.1mM. Fish infused with exogenous lactate stimulated Rd lactate by 300% (14 to 56 μmol kg-1 min-1) during graded exercise, whereas the Rd in resting fish increased by only 90% (21 to 40 µmol kg-1 min-1). Four MCT isoforms were partially cloned and characterized in rainbow trout: MCT1b was the most abundant in heart, and red muscle, but poorly expressed in gill and brain where MCT1a and MCT2 were prevalent. MCT4 was more expressed in the heart. Transcript levels of MCT2 (+260%; brain), MCT1a (+90%; heart) and MCT1b (+50%; heart) were stimulated by exhausting exercise. This study shows that: (i) the increase in Rd lactate plays a strategic role in reducing the lactate load imposed on the circulation. Without this response, blood lactate accumulation would double; (ii) a high capacity for lactate disposal in rainbow trout tissues is elicited by the increased blood-to-tissue lactate gradient when extra lactate is administered; and (iii) rainbow trout may be unable to release large lactate loads rapidly from white muscle after exhausting exercise (lactate retention) because they poorly express MCT4 in white muscle and fail to upregulate its expression during exercise.

The focus of this research is on the specific relational and particular circumstances that result in an emerging cancer identity expressed through the daily lived- experiences of emerging adults via personal weblogs. Identity, a complex term in its own right, is discussed here under the rubric of social identity as processual, therefore it is expected that an emerging cancer identity will develop as the participants begin to narrativize their daily experiences with cancer on their weblogs. By critically engaging with notions of emerging adulthood theories with theories on the sociology of death and dying and illness narratives, this research seeks to understand the specific psychosocial changes that occur as the participants engage with their illness on their weblogs, which arguably contributes to an emerging cancer identity.

In this dissertation, I examine the constructions, maintenance, and resistance to dominant discourses concerning motherhood and non-motherhood in contemporary Hungary, using the popular Hungarian women’s magazine Nők Lapja as my key illustrative example. I strive to illuminate how gendered discourses, bio-power, history, and geo-politics are implicated not only in the construction of nationhood but also in defining women’s roles in nation-building. I hope to contribute to research that helps to better understand women’s contemporary social roles in Hungary, and the power relations that construct them. I argue that ideas regarding motherhood and non-motherhood in Hungary are often bound up in ideas concerning who should, or should not, have children, and why, and I explore in detail how these ideas have formed through the history of the nation. My analysis reveals different sites of power—focusing on policy and print media—that seek to determine women’s procreative decisions. I argue that, under various regimes, women’s procreative choices have consistently been systemically constrained, and framed as key to the nation’s success—or failure. Concerning Nők Lapja magazine, my research reveals that it both supports and resists traditional gender roles, at times contributing to discourses that naturalize childbearing and motherhood (also defining for readers whose motherhood is deemed desirable), but at other times disputing such ideas and redefining conceptions of womanhood to include women without children. Although ultimately the magazine pathologizes, disbelieves and negates the choice to be childless, Nők Lapja does resist and redefine limited definitions of womanhood and motherhood by carving out a small space for discussions of childlessness, and also by challenging conceptions of singletons as necessarily lonely and mothers as necessarily better if they stay at home.