The Master of Fine Arts exhibition, Undesirable Forms, presents a collection of paintings and sculptures that focus on the repulsion and discomfort a woman can experience within her mind and body. These works were exhibited at the Tipton gallery, in downtown Johnson City. The pieces included in this exhibition consist of encaustic paintings on panel, and sculptures created from plaster life-casts. The ideas discussed in this paper are influenced by Julia Kristeva and Sigmund Freud’s work relating to the abject/grotesque female body. This paper also discusses inspiration from other artists, such as Natalie Frank and Helen Chadwick, who work with psychological subject matter and the female body.

Objective: To describe foreign bodies (FBs) in the nasolacrimal sac of dogs, the history, and simple diagnostic and therapeutic approaches. Animals studied Fourteen dogs of different breeds, ages, and sexes were presented with unilateral dacryocystitis and had been treated without success for over 1–8 months. Procedures: Patient history, including prior treatment, was obtained from medical records. Slit-lamp examination was performed in all cases (SL 17, Kowa Company Ltd.). Jones tests 1 and/or 2 were performed in 13/14 cases. Dacryocystotomy was initiated with an incision into one canaliculus until the lacrimal sac was exposed and could be explored. After extracting the FB from the nasolacrimal sac, the surgical wound and canaliculus were left open. Aftercare included the administration of antibiotic eye drops with or without dexamethasone and systemic analgesia. Results: All 14 dogs were mesocephalic. Four of them were Dachshunds. Dacryocystotomy revealed plant-related FBs in all cases. The purulent discharge disappeared immediately after removal and did not recur during follow-up. Conclusions: A simple dacryocystotomy is recommended for dogs with a strong suspicion of a foreign body in the lacrimal drainage system. Dacryocystorhinography appears to be an optional tool in these cases.

In order to develop a better understanding of the role of the froth phase in coal flotation, froth stability measurements have been conducted using a continuous flotation cell. The results indicate that the mass flow rate of coal or mineral matter reporting to the product is linearly related to the flow rate of water reporting to the product. This relationship has been used to distinguish the relative contributions of hydrophobic attachment or hydraulic entrainment to the total product recovery. Simple mathematical expressions have also been developed to characterize the cleanability of various coals. A mathematical model based on first principles has been developed to provide additional insight into the complex relationship between the various operating parameters of a flotation cell and the froth behavior. The predicted results compare favorably to actual flotation test data for most conditions. In addition, a simple method was developed to study the fundamental interactions of various frothing agents with coal particles. The results of these studies indicate that the adsorption behavior of frothers in the presence of coal depends on both the physical properties of the frothing agent and the coal. / Master of Science

<p> In this dissertation the author provides an analysis of three separate but interrelated aspects of the experiences of women who have been treated for breast cancer and who participate in survivor dragon boat racing.</p> <p> In the first analysis the author addresses the multiple meanings and functions that this physically intense competitive team sport has for the women. The paper explores some of the reasons why this activity appealed to them and the kinds of impacts and effects that participation in this activity had on their lives. The second analysis offers a critical look at the ways in which breast amputation has been characterised within the medical and breast cancer literature as a threat to women's self identity as female or feminine. The data from this study however demonstrates that women's experiences of breast amputation is much more complex and nuanced than characterised. Also included is an examination of women's own perspectives on this experience, as well as the mediating role that dragon boat racing had on this aspect of self identity. The third analysis focusses on a major theme that emerged from the data which was the transformative effect that competitive dragon boat racing had on women's bodies and on their sense of self. Discussed here are the impacts and effects that participation in competitive dragon boat racing had on women's self identities and bodies and that enabled the women to see themselves as strong, fitter, healthier and "better" than what they were prior to their breast cancer illness experience. Finally, the author concludes with a discussion of how regular participation sport, and especially for women living with a critical illness, can empower women at the individual, group and societal levels.</p> / Thesis / Doctor of Philosophy (PhD)

TRF1, telomeric-repeat binding factor 1, is a component of the six-subunit protein complex, referred to as shelterin, which is essential for not only regulating telomere length maintenance but also protecting mammalian telomeres from being recognized as damaged DNA. TRF1 acts as a negative mediator of telomerase-dependent telomere elongation in telomerase-expressing cells, whereas it promotes alternative lengthening of telomeres (ALT) activity by regulating ALT features including the production of extrachromosomal telomere-repeat (ECTR) DNA such as C-circles, and ALT-associated promyelocytic leukemia bodies, or APBs. The activity of TRF1 is tightly regulated by post-translational modification such as phosphorylation. This thesis sets out to investigate the function of TRF1 phosphorylation on threonine-271 (T271) and threonine-371 in telomere maintenance. The results presented in this thesis demonstrate that TRF1 phosphorylation on T271 positively regulates the association of TRF1 to telomeric DNA in telomerase expressing cells. In ALT cells, TRF1 phosphorylation on both T271 and T371 is shown to be important for the formation of APBs. Furthermore, the work presented here suggests that transcription-associated DNA damage mediates the association of phosphorylated (pT371)TRF1 with APBs. / Thesis / Master of Science (MSc) / TRF1, telomeric-repeat binding factor 1, is a component of the shelterin complex, which is essential for regulating telomere length maintenance and protecting mammalian telomeres from being recognized as damaged DNA. TRF1 acts as a negative mediator of telomerase-dependent telomere elongation in telomerase-expressing cells, whereas it promotes alternative lengthening of telomeres. The activity of TRF1 is tightly regulated by phosphorylation. This thesis sets out to investigate the function of TRF1 phosphorylation on threonine-271 and threonine-371 in telomere maintenance. Understanding how post-translational modifications on TRF1 may be linked to telomere homeostasis will be crucial for our understanding in cancer cell biology.

Through the Zohar, the major medieval kabbalistic work, the human body is used in order to symbolise the divine structure. Present throughout are also dire warnings against the dangers of the flesh – a sense of anxiety often surrounds matters of the body. This study examines how the central notion of the body as created in God’s image relates to the negative zoharic characterizations of the body and further, how notions of gender and Jewish religious affiliation are reflected in the zoharic views of the body. The results show that characterizations of the body can work to reinforce boundaries and define the own group. The female body is valued differently than the male, the Jewish differently than the non-Jewish body. The idealized human body belongs to the circumcised Jewish male who adheres to proper religious behaviour. The aim of this thesis is to enrich our understanding of the human body as depicted in the major kabbalistic tradition of the Zohar.

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