O empreendimento Gasoduto Urucu-Coari-Manaus é uma rede de tubulações que conduz o gás natural do Terminal Solimões TESOL do município de Coari até a Refinaria de Manaus REMAN, na cidade de Manaus, Estado do Amazonas. A tubulação do gasoduto ocupa uma extensão de aproximadamente 700 km, atravessando territórios dos sete municípios do Estado do Amazonas: Coari, Codajás, Anori, Anamã, Caapiranga, Manacapuru e Iranduba. A jazida de gás natural da bacia do Solimões/Amazonas sinaliza um elevado potencial de desenvolvimento regional na geração de energia a gás. Seu aproveitamento vem sendo apontado como um marco de referência na economia da Amazônia Ocidental. Em 1998, na mesma faixa de oleoduto de Urucu até o Terminal do Solimões, foi construído o trecho do Gasoduto para Manaus. A construção do gasoduto pode ser um fator de desenvolvimento socioeconômico em uma região de poucas opções principalmente de fontes energéticas. Neste sentido, o estudo do recurso natural (gás) do gasoduto em questão e de seus impactos ambientais e socioeconômicos tornam-se cada vez mais importante, pois contribuem com a pesquisa nessa área e poderão ser observados os resultados destes, especialmente, na cidade de Manacapuru-AM. Este trabalho demonstra a importância dos questionamentos a cerca da exploração dos recursos naturais, desenvolvimento econômico, social e preservação do meio ambiente. Assim, em ciência geográfica pode-se afirmar que a temática Recurso Natural, exige uma abordagem que considera aspectos sociais e naturais. Por um lado, o recurso é algo ao qual se recorre, portanto é histórico, por outro, é natural e exige o conhecimento da dinâmica da natureza para se compreender sua ocorrência e distribuição na superfície ou crosta terrestre. Este trabalho desenvolveu-se in loco verificando a relevância da implantação do Gasoduto Urucu-Coari-Manaus analisando os aspectos sociais e econômicos no referido município. / The project Urucu-Coari-Manaus pipeline network is a leading natural gas Solimões Terminal - TESOL in the city of Coari to Manaus Refinery - REMAN in the city of Manaus, in Amazonas state. The pipe of the pipeline occupies an area of approximately 700 km across the territories of the seven counties of the State of Amazonas Coari Codajás, Anori, Anamã, Caapiranga, Manacapuru and Iranduba. With this natural gas field in the basin of the Solimões / Amazonas, signals to a high potential for regional development in power generation gas. Its use has been appointed as a benchmark in the economy of the Western Amazon. In 1998, in the same range of pipeline Urucu to the Solimões Terminal, was built the section of pipeline to Manaus. The construction of the pipeline may be a factor of socio-economic development in a region with few options especially for energy sources. In this sense, the study of natural resource (gas) pipeline in question and its environmental and socioeconomic impacts becomes increasingly important as it contributes to research in this area and may be seen the results of environmental and socioeconomic impacts, especially in the city of Manacapuru-AM. This research demonstrates the importance of natural resources in the questioning of economic development with environmental preservation. Thus, in geographical science can say that the theme \"Natural Resource\", requires an approach that considers the social and natural. On the one hand, the feature is something to which it refers, so it is historical, the other is natural and requires knowledge of the dynamics of nature to understand their occurrence and distribution on the surface or crust. This research has developed on-site checking the relevance of deployment of the Urucu-Coari-Manaus analyzing the social and economic aspects in that municipality.

This paper details the design and development process for two technical projects, both of which were developed for use in Autodesk Maya to enhance the workflow processes of 3D character animation. The first project is focused on advanced character rigging using mathematical concepts and Maya nodes, while the second project is focused on plugin development in python 2.7, making full use of the PySide2 library which binds to the Qt5 user-interface framework.

abstract: This thesis presents the design and testing of a soft robotic device for water utility pipeline inspection. The preliminary findings of this new approach to conventional methods of pipe inspection demonstrate that a soft inflatable robot can successfully traverse the interior space of a range of diameter pipes using pneumatic and without the need to adjust rigid, mechanical components. The robot utilizes inflatable soft actuators with an adjustable radius which, when pressurized, can provide a radial force, effectively anchoring the device in place. Additional soft inflatable actuators translate forces along the center axis of the device which creates forward locomotion when used in conjunction with the radial actuation. Furthermore, a bio-inspired control algorithm for locomotion allows the robot to maneuver through a pipe by mimicking the peristaltic gait of an inchworm. This thesis provides an examination and evaluation of the structure and behavior of the inflatable actuators through computational modeling of the material and design, as well as the experimental data of the forces and displacements generated by the actuators. The theoretical results are contrasted with/against experimental data utilizing a physical prototype of the soft robot. The design is anticipated to enable compliant robots to conform to the space offered to them and overcome occlusions from accumulated solids found in pipes. The intent of the device is to be used for inspecting existing pipelines owned and operated by Salt River Project, a Phoenix-area water and electricity utility provider. / Dissertation/Thesis / Masters Thesis Engineering 2019

Die Sequenzierungstechnologien entwickeln sich stetig weiter, dies ermöglicht eine zuvor nicht erreichte Ausbeute an experimentellen Daten und auch an Neuentwicklungen von zuvor nicht realisierbaren Experimenten. Zugleich werden spezifische Datenbanken, Algorithmen und Softwareprogramme entwickelt, um die neu entstandenen Daten zu analysieren. Während der Untersuchung bioinformatischer Methoden für die Identifizierung und Klassifizierung somatischer Mutationen in hämatologischen Erkrankungen, zeigte sich eine hohe Vielfalt an alternativen Softwaretools die für die jeweiligen Analyseschritte genutzt werden können. Derzeit existiert noch kein Standard zur effizienten Analyse von Mutationen aus Next-Generation-Sequencing (NGS)-Daten. Die unterschiedlichen Methoden und Pipelines generieren Kandidaten, die zum größten Anteil in allen Ansätzen identifiziert werden können, jedoch werden Software spezifische Kandidaten nicht einheitlich detektiert. Um eine einheitliche und effiziente Analyse von NGS-Daten durchzuführen war im Rahmen dieser Arbeit die Entwicklung einer benutzerfreundlichen und einheitlichen Pipeline vorgesehen. Hierfür wurden zunächst die essentiellen Analysen wie die Identifizierung der Basen, die Alignierung und die Identifizierung der Mutationen untersucht. Des Weiteren wurden unter Berücksichtigung von Effizienz und Performance diverse verfügbare Softwaretools getestet, ausgewertet und sowohl mögliche Verbesserungen als auch Erleichterungen der bisherigen Analysen vorgestellt und diskutiert. Durch Mitwirken in Konsortien wie der klinischen Forschergruppe 216 (KFO 216) und International Cancer Genome Consortium (ICGC) oder auch bei Haus-internen Projekten wurden Datensätze zu den Entitäten Multiples Myelom (MM), Burkitt Lymphom (BL) und Follikuläres Lymphom (FL) erstellt und analysiert. Die Selektion geeigneter Softwaretools und die Generierung der Pipeline basieren auf komparativen Analysen dieser Daten, sowie auf geteilte Ergebnisse und Erfahrungen in der Literatur und auch in Foren. Durch die gezielte Entwicklung von Skripten konnten biologische und klinische Fragestellungen bearbeitet werden. Hierzu zählten eine einheitliche Annotation der Gennamen, sowie die Erstellung von Genmutations-Heatmaps mit nicht Variant-Calling-File (VCF)-Syntax konformen Dateien. Des Weiteren konnten nicht abgedeckte Regionen des Genoms in den NGS-Daten identifiziert und analysiert werden. Neue Projekte zur detaillierten Untersuchung der Verteilung von wiederkehrender Mutationen und Funktionsassays zu einzelnen Mutationskandidaten konnten basierend auf den Ergebnissen initiiert werden. Durch eigens erstellte Python-Skripte konnte somit die Funktionalität der Pipeline erweitert werden und zu wichtigen Erkenntnissen bei der biologischen Interpretation der Sequenzierungsdaten führen, wie beispielsweise zu der Detektion von drei neuen molekularen Subgruppen im MM. Die Erweiterungen, der in dieser Arbeit entwickelten Pipeline verbesserte somit die Effizienz der Analyse und die Vergleichbarkeit unserer Daten. Des Weiteren konnte durch die Erstellung eines eigenen Skripts die Analyse von unbeachteten Regionen in den NGS-Daten erfolgen. / The sequencing technologies, while still being under further development, render it possible to develop novel experiments and allow the generation of larger amounts of utilizable data. At the same time novel software tools, databases and algorithms are developed to analyze these larger amounts of data. The analysis of somatic mutations in hematological malignancies showed that a high variety of alternative software tools can be used for different analysis steps. Furthermore there is currently no standardized procedure for the efficient identification and analysis of mutations in NGS data. The different pipeline and methods are, for the most part, able to identify the same mutation candidates, however there are software specific candidates which are not called by all pipelines. The scope of this dissertation was therefore to develop a user-friendly pipeline which is able to call candidate mutations uniformly and efficiently. For this purpose necessary analysis steps including base calling, alignment generation and variant calling were investigated. Furthermore available software tools were tested and evaluated regarding their efficiency and performance. Possible improvements of these software tools and previously performed analysis are explained and discussed in this work. NGS data sets of the different cancer entities multiple myeloma (MM), Burkitt lymphoma (BL) and follicular lymphoma (FL) were generated and analyzed within the framework of cooperate projects like the International Cancer Genome Consortium (ICGC) and the Clinical Research Group 216 (KFO) as well as for internal projects. The development of the pipeline and selection of suitable software tools is based on the comparative analysis of the generated data sets, as well as previously described results and experiences in literature and forums. The selective development of certain python scripts enabled the evaluation of novel biological and clinical questions by standardizing gene names in the annotation step, generating heat- maps of non-standardized VCF-files as well as the identification and analysis of uncovered regions in NGS data sets. This work and the obtained results thereby provide the groundwork for further projects e.g. the analysis of the distribution of recurrent mutations or the functional analysis of specific mutation candidates. This extensions of the developed pipeline with python scripts helped to improve the efficiency and comparability of the NGS data. The interpretation of the NGS data with the extended script for example led to the discovery of three distinct molecular subgroups in MM. Furthermore the generation of the novel python scripts helped to analyze uncovered regions in the NGS data sets.

This dissertation applies a commercial flow simulation software package together with common signal processing techniques to the task of accurately detecting leakage in a large commercial gas pipeline. The techniques developed significantly improved the ability to produce accurate, reliable and stable leak detection predictions for the gas transmission pipeline studied and can be applied generally to other pipelines as well. Recommendations for minimum pipeline requirements to implement successful leak detection are also detailed. There are several commercial software packages available that perform some form of leak detection via system modelling. However, due to the commercial aspects of these products, vendors do not publish the detailed methods of leak detection. This thesis identifies the fundamental techniques required to have accurate and reliable leak detection on a gas transmission pipeline, whilst taking into account the lack of measurement data typically encountered on most gas pipelines. The investigation confirmed that a mass balance technique could be successfully used to produce stable leak detection results for compressible flow in gas transmission pipelines. This leak detection [using mass balance] can be achieved without flow measurement along the pipeline, instead, using only pressure and temperature measurements. Although it is recognized that flow measurement data will greatly improve the ability to detect leaks, the focus of this work is on pipelines where this flow measurement data at intermediate points along the pipeline is not available. It was also demonstrated the reliability of the leak detection was improved by the application of on-line signal processing techniques at various stages of the data processing. / It was clear early into the investigation that the majority of the errors within the leak detection model were created by random errors from the input field data. These non-systematic errors from the measurement data that included pressure and temperature, produced interference with model output. This interference resembled random “white” noise that was removed by a combination of well established data filtering techniques. The most appropriate process of calculating leak detection flow was determined after analysing the results of different techniques applied to large quantities of actual pipeline operating data. The validation of the on-line techniques developed provides a valuable resource for those wishing to implement similar leak detection schemes elsewhere. Furthermore a software environment was chosen which incorporated an open input and output platform for data that could be interfaced with any operating system. Therefore these techniques can be applied to the numerous Supervisory Control and Data Acquisition (SCADA) systems in operation throughout the gas transmission industry, to provide a low cost solution to leak monitoring.

The digital product increases widely and vastly. Because we live in the analog world, we require a converter to change analog signal to digital one. However, the requirement of analog-to-digital converter is rising due to progress of DSP (Digital Signal Processor). For portable products, the power consumption also needs to take into account. As mentioned above, I will implement a high speed and low power analog to digital converter. In this thesis, the circuits are designing with TSMC.18 1P6M CMOS process and 1.8V of supply voltage. The speed and resolution of ADC are 100Ms/s and 12bits individually. The pipelined coupling with 1.5bit/stage constitutes the main architecture of analog-to-digital converter. The dynamic comparator is used for lower power. Finally, the output codes are translated by digital correction circuit.

Water-in-oil (W/O) emulsions consist of water droplets dispersed in continuous oil phase. They are encountered at various stages of oil production. The oil produced from an oil-well usually carries a significant amount of water in the form of droplets. In enhanced oil recovery techniques involving the injection of polymer solution, the aqueous phase of the water-in-oil emulsions produced from the oil well consists of polymeric additive. A good understanding of the flow behavior of emulsions in pipelines is essential for the design and operation of oil production-gathering facilities and emulsion pipelines. A number of studies have been reported on simultaneous flow of oil and water in pipelines. However, the studies reported in the literature are mainly focused on either oil-water flow patterns and separated flows (annular and stratified flow of oil and water phases) or oil-in-water (O/W) emulsion flows. The pipeline flow of water-in-oil (W/O) emulsions has received less attention. Also, little work has been carried out on the effect of additives such as polymer. In this study, new experimental results are presented on the pipeline flow behavior of water-in-oil (W/O) emulsions, with and without the presence of polymeric additive in the aqueous phase. The emulsions were prepared from three different oils, namely EDM-244, EDM-Monarch, and Shell Pella of different viscosities (2.5 mPa.s for EDM-244, 6 mPa.s for EDM-Monarch, and 5.4 mPa.s for Shell Pella, at 25 0C). The water-in-oil emulsions prepared from EDM-244 and EDM-Monarch (without any polymeric additive in the dispersed aqueous phase) exhibited drag reduction behavior in turbulent flow. The turbulent friction factor data of the emulsions fell well below the standard Blasius equation for smooth pipes. The water-in-oil emulsions prepared from EDM-244 exhibited stronger drag reduction as compared with the EDM-Monarch emulsions. The Shell Pella emulsions (w/o type) did not exhibit any drag reduction in turbulent flow; the friction factor data followed the Blasius equation. The Shell Pella emulsions were more stable than the EDM-244 and EDM-Monarch emulsions. When left unstirred, the EDM-244 and EDM-Monarch emulsions quickly coalesced into separate oil and water phases whereas the Shell Pella emulsions took significantly longer time to separate into oil and water phases. The Shell Pella oil emulsions were also milkier than the EDM emulsions. The addition of polymer to the dispersed aqueous phase of water-in-oil emulsions had a significant effect on the turbulent drag reduction behavior. Emulsions were less drag reducing when polymer was present in the aqueous droplets. The effect of surfactant on the pipeline flow behavior of water/oil emulsions was also investigated. The surfactant-stabilized water-in-oil emulsions followed the single phase flow behavior. The presence of surfactant in the emulsions caused the dispersed droplets to become significantly smaller. It is believed that the droplets were smaller than the scale of turbulence when surfactant was present and consequently no drag reduction was observed.

Water-in-oil (W/O) emulsions consist of water droplets dispersed in continuous oil phase. They are encountered at various stages of oil production. The oil produced from an oil-well usually carries a significant amount of water in the form of droplets. In enhanced oil recovery techniques involving the injection of polymer solution, the aqueous phase of the water-in-oil emulsions produced from the oil well consists of polymeric additive. A good understanding of the flow behavior of emulsions in pipelines is essential for the design and operation of oil production-gathering facilities and emulsion pipelines. A number of studies have been reported on simultaneous flow of oil and water in pipelines. However, the studies reported in the literature are mainly focused on either oil-water flow patterns and separated flows (annular and stratified flow of oil and water phases) or oil-in-water (O/W) emulsion flows. The pipeline flow of water-in-oil (W/O) emulsions has received less attention. Also, little work has been carried out on the effect of additives such as polymer. In this study, new experimental results are presented on the pipeline flow behavior of water-in-oil (W/O) emulsions, with and without the presence of polymeric additive in the aqueous phase. The emulsions were prepared from three different oils, namely EDM-244, EDM-Monarch, and Shell Pella of different viscosities (2.5 mPa.s for EDM-244, 6 mPa.s for EDM-Monarch, and 5.4 mPa.s for Shell Pella, at 25 0C). The water-in-oil emulsions prepared from EDM-244 and EDM-Monarch (without any polymeric additive in the dispersed aqueous phase) exhibited drag reduction behavior in turbulent flow. The turbulent friction factor data of the emulsions fell well below the standard Blasius equation for smooth pipes. The water-in-oil emulsions prepared from EDM-244 exhibited stronger drag reduction as compared with the EDM-Monarch emulsions. The Shell Pella emulsions (w/o type) did not exhibit any drag reduction in turbulent flow; the friction factor data followed the Blasius equation. The Shell Pella emulsions were more stable than the EDM-244 and EDM-Monarch emulsions. When left unstirred, the EDM-244 and EDM-Monarch emulsions quickly coalesced into separate oil and water phases whereas the Shell Pella emulsions took significantly longer time to separate into oil and water phases. The Shell Pella oil emulsions were also milkier than the EDM emulsions. The addition of polymer to the dispersed aqueous phase of water-in-oil emulsions had a significant effect on the turbulent drag reduction behavior. Emulsions were less drag reducing when polymer was present in the aqueous droplets. The effect of surfactant on the pipeline flow behavior of water/oil emulsions was also investigated. The surfactant-stabilized water-in-oil emulsions followed the single phase flow behavior. The presence of surfactant in the emulsions caused the dispersed droplets to become significantly smaller. It is believed that the droplets were smaller than the scale of turbulence when surfactant was present and consequently no drag reduction was observed.

Because IC (Integrated Circuit) has some good features like: little, low power consumption, and high stable, so it already popularly applied to our daily life. Operation is one of the main functions of IC, and now operate function achieve in digital mode of many IC products. Although digital circuits have many advantages, but we live in the analog world, natural signals are all analog. Digital circuits can¡¦t direct process analog signals, and therefore we have a requirement of analog-to-digital converter. As time goes by, IC technology has made great progress; digital circuits have faster process ability, and we also require a high speed analog-to-digital converter. Besides, in order to achieve higher picture quality and clearer voice, we also require a high resolution analog-to-digital converter. For portable products, the power consumption also needs to take into account. As mentioned above, I will implement a high speed, high resolution and low power analog-to-digital converter. In this thesis, the circuits are designing with TSMC.18£gm 1P6M CMOS process and 1.8V of supply voltage. The speed and resolution of ADC are 100Ms/s and 12bits individually. The pipelined coupling with 1.5bit/stage constitutes the main architecture of analog-to-digital converter. The dynamic comparator is used for lower power. Finally, the output codes are translated by digital correction circuit. Keywords: ADC, Analog-to-Digital Converter, pipeline, low power, amplifier, comparator.

This research is aimed at assessing the quantitative risks involved with an ethanol pipeline. Pipelines that run from the Midwest, where the vast majority of ethanol is produced, to the target areas where reformulated gasoline is required (California, Texas Gulf Coast, New England Atlantic Coast) will be of particular interest. The goal is to conduct a quantitative risk assessment on the pipeline, truck, and rail transportation modes to these areas. As a result of the quantitative risk assessment, we are able to compare the risk associated with the different modes of transportation for ethanol. In order to perform and compare the quantitative risk assessment, the following challenges are addressed: • Identify target areas requiring reformulated gasoline • Map detailed route for each transportation mode to all three target areas • Perform a quantitative risk assessment for each transportation mode • Compare quantitative risk assessment results for each route and transportation mode The focus is on California, Texas Gulf Coast, and New England Atlantic Coast because of the large volume. It is beneficial to look at these areas as opposed to the smaller areas because pipeline transportation requires very large volumes. In order to find a meaningful comparison between all three transportation modes, only the areas with the three large volumes were evaluated. Since the risk assessment is completed using historical data, each route is segmented in a way that is consistent with the data that is available. All of the curves support the hypothesis that pipeline transportation poses the least societal risk when transporting ethanol from the Midwest to target areas. Rail transportation poses the largest amount of societal risk. While overall rail incidents are not as frequent as road incidents, the frequency of a fatality is much higher when an incident does occur.