This thesis deals with the use of mindfulness techniques at adult clients with ADHD aiming to determine the beneficial effects of this kind of intervention. An eight-week long mindfulness course carried out by means of the action research was attended by twelve adults with ADHD in total. The course designed as eight individual online meetings helped to get a deeper insight into the benefit and demands of the individual techniques as they are perceived by the participants. The level of the attentiveness change was monitored by the Face Facet Mindfulness Questionnaire (FFMQ-15-CZ) both before and after attending the course. The analysis of the participants' answers, which have become the main method to collect the data, shows that the mindfulness method has brought changes in the participants' lives; among them getting conscious, present, the ability to slow down, calm down and stop, thanks to which they have managed to better face the ADHD manifestation. Mindfulness appears to be another possible intervention which can help adults to reduce difficulties caused by this disorder.

Inom stadsutvecklingen har bilen länge haft en dominerade ställning, med tiden har den dock kommit att bli allt mer ifrågasatt. Flera alternativa planeringsmodeller har tagits fram för att minska bilberoendet varav Morenos 15-minuterstad är en som fått stort genomslag. Dock har mycket få studier gjorts i en nordisk kontext där befolkningstätheten är låg. Syftet har därför varit att undersöka åsikter om 15-minuterstadens centrala pelare och möjligheten till förändrade resvanor i en medelstor svensk stad. Syftet besvarades med en enkät samtidigt som en dokumentanalys genomfördes över stadens översiktsplan med tillhörande trafikstrategi (2010). Resultatet från studien visade att både kommunen och invånare är generellt positivt inställda till 15-minuterstaden men det finns ett visst motstånd till en fullständig implementation. Social practice theory har använts i analysen för att förstå människors svårföränderliga vanor, vilka kan brytas ner till material, kompentens och mening. Materialaspekten har förändrats genom ny infrastruktur vilket kommunen motiverar med ny kompetens om hållbarhet. Invånarna tillskriver 15-minuterstaden en positiv mening genom bemärkelser som rörelse, omväxling, tillgänglighet, bekvämlighet, trygghet och flexibilitet. / Within urban development, the car has long had a dominant position, but over time it has come to be increasingly questioned. Several alternative planning models have been proposed to reduce car dependence, of which Moreno's 15-minute city is one that has become very popular. However, very few studies have been conducted in a Nordic context where the population density is low. The purpose has therefore been to examine opinions about the central pillars of the 15-minute city and the possibility of changing travel habits in a medium-sized Swedish city. The purpose was answered with a survey at the same time as a document analysis was carried out on the city's general plan with associated traffic strategy (2010). The results of the study showed that both the municipality and residents are generally positive about the 15-minute city, but there is some resistance to a full implementation. Social practice theory has been used in the analysis to understand people's hard-to-change habits, which can be broken down into material, competence and meaning. The material aspect has changed through new infrastructure, which the municipality justifies with new competence in sustainability. The residents attribute a positive meaning to the 15-minute city through meanings such as movement, change, accessibility, convenience, safety, and flexibility.

Inhibition of cyclooxygenase (COX)-2 increases cardiovascular deaths. Identifying a biomarker of COX-2 is desirable but difficult, since COX-1 and COX-2 ordinarily catalyze formation of an identical product, prostaglandin H2. When acetylated by aspirin, however, COX-2 (but not COX-1) can form 15(R)-HETE, which is metabolized to aspirin-triggered lipoxin (ATL), 15-epi-lipoxin A4. Here we have used COX-1- and COX-2-knockout mice to establish whether plasma ATL could be used as a biomarker of vascular COX-2 in vivo. Vascular COX-2 was low but increased by LPS (10 mg/kg; i.p). Aspirin (10 mg/kg; i.v.) inhibited COX-1, measured as blood thromboxane and COX-2, measured as lung PGE2. Aspirin also increased the levels of ATL in the lungs of LPS-treated wild-type C57Bl6 mice (vehicle: 25.5±9.3 ng/ml; 100 mg/kg: 112.0±7.4 ng/ml; P<0.05). Despite this, ATL was unchanged in plasma after LPS and aspirin. This was true in wild-type as well as COX-1−/− and COX-2−/− mice. Thus, in mice in which COX-2 has been induced by LPS treatment, aspirin triggers detectable 15-epi-lipoxin A4 in lung tissue, but not in plasma. This important study is the first to demonstrate that while ATL can be measured in tissue, plasma ATL is not a biomarker of vascular COX-2 expression.—Kirkby, N. S., Chan, M. V., Lundberg, M. H., Massey, K. A., Edmands, W. M. B., MacKenzie, L. S., Holmes, E., Nicolaou, A., Warner, T. D., Mitchell, J. A. Aspirin-triggered 15-epi-lipoxin A4 predicts cyclooxygenase-2 in the lungs of LPS-treated mice but not in the circulation: implications for a clinical test.

Submitted by Silvana Teresinha Dornelles Studzinski (sstudzinski) on 2015-07-01T18:20:11Z No. of bitstreams: 1 Geovana Zimmermann Los.pdf: 1707837 bytes, checksum: 42f45d5024c990c07d9c215480e1fa6d (MD5) / Made available in DSpace on 2015-07-01T18:20:11Z (GMT). No. of bitstreams: 1 Geovana Zimmermann Los.pdf: 1707837 bytes, checksum: 42f45d5024c990c07d9c215480e1fa6d (MD5) Previous issue date: 2014-03-28 / Nenhuma / O objetivo do estudo foi verificar o impacto no valor adicionado a distribuir das variáveis evidenciadas, segundo a NBCT 15, por empresas classificadas no ISE. A pesquisa foi realizada com uma amostra formada por 75 relatórios de sustentabilidade, de 25 empresas que permaneceram na carteira do ISE no período de 2010 a 2012. Os resultados revelam que o grupo de indicadores do corpo funcional apresenta o maior percentual de atendimento à evidenciação de informações requeridas pela NBC T 15, uma vez que estes são evidenciados em 62,67% dos relatórios das empresas da amostra, seguidos do grupo de indicadores sociais internos, com 55,92%, e do grupo de indicadores sociais externos, divulgados em 47,33% dos relatórios. Já o grupo de indicadores relacionados com o meio ambiente apresenta o percentual médio mais baixo em termos de aderência, com índices de 26,67%. Com isso, o nível geral de aderência das empresas da amostra aos indicadores da NBC T 15 é de 49,6%, revelando fragilidade no quesito transparência. Nesse sentido, utilizando-se a análise de regressão com dados em painel para modelo de efeito fixo e de efeito aleatório, foi testado o impacto das variáveis “gastos sociais internos”, “número de funcionários”, “gastos sociais externos” e “gastos em meio ambiente no valor adicionado a distribuir das empresas”. No resultado para o modelo de efeito aleatório, é possível rejeitar H0, diante da hipótese H0,1, e confirmar a hipótese H1 formulada. Assim, o estudo revela que quanto maior o gasto com indicadores sociais internos, maior seria o valor adicionado a distribuir das organizações da amostra. Para as hipóteses H0,2 e H0,4 , é rejeitada a hipótese H0 a 5% de significância e, com isso, pode-se confirmar as hipóteses H2 e H4 do estudo, respectivamente. Dessa forma, o resultado demonstra que quanto maior o nível de funcionários das empresas da amostra, bem como quanto maiores forem os gastos com meio ambiente, maior será o valor adicionado a distribuir por elas. / The aim of the study was to determine the impact, on the added value to distribute of evidenced variables, according to NBCT 15, by companies classified on the ISE. The survey was conducted with a sample consisting of 75 sustainability reports, of 25 companies which remained on the ISE in the period 2010-2012. The results show that the group of indicators of functional staff shows the highest percentage of attendance to the disclosure of information required by NBC T 15, since these are observed in 62.67% of sample companies’s reports, followed by the group of internal social indicators, with 55.92%, and the group of external social indicators, published in 47.33% of the reports. The group of indicators related to the environment presents the lowest average percentage in terms of adhesion, with rates of 26.67%. With this, the overall adherence level of the sample companies to the indicators of NBC T 15 is 49.6%, revealing weaknesses in the category transparency. In this sense, using regression analysis, with panel data for the fixed effect and random effect model, it was tested the impact of variables "internal social spending," "number of employees", "external social costs" and "Spending on the environment in the value added to be distributed by companies". In the results for the random effect model, it is possible to reject H0,, given the hypothesis H0,1, Thus, the study reveals that higher is the spending on domestic social indicators, higher is the sample organizations’ added value to distribute; For the hypotheses H0,2 e H0,4 , is rejected hypothesis H0 at 5% significance, and, thus, it can be confirmed the H2 and H4 hypotheses of the study, respectively. Thus, the result shows that higher is the level of employees of companies in the sample, as well as higher is the spending on the environment, higher will be the value added to be distributed by them.

Esta dissertação tem como objectivo analisar a relação entre as ocupações de mercador e de banqueiro, em Portugal, nos séculos XIV e XV, assim como compreender as dinâmicas mercantis, sob os pontos de vista do comércio, dos câmbios, empréstimos e finanças.

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Im Vortrag wird die Vorgehensweise zur Modellierung des Ventiltriebs eines Einzylinder-Motorradmotors beschrieben. Dieser setzt sich aus zwei gebauten, wälzgelagerten Nockenwellen zusammen. Die Ventile werden über Schlepphebel betätigt. Das Hauptaugenmerk liegt dabei auf den Pressverbindungen zwischen Nocken und Welle sowie auf den Wälzlagerungen. Um die Belastungszustände zu ermitteln ist eine detaillierte Simulation nötig. Diese Mehrkörpersimulation wird in Mathcad mit Hilfe eines eigenen Lösers durchgeführt.

This thesis aims to analyze legislation of the Czech legal order concerning religious freedom. The work is divided in two parts. The first part of the thesis deals with the definition of religious freedom in the first place. Afterwards the thesis describes the Constitutional law relating to the religious freedom (especially the Article No. 15 and No. 16 of the Charter of the Fundamental Rights and Freedoms of the Czech Republic), international conventions relating to the theme (e.g. The Universal Declaration of Human Rights, The International Covenant on Civil and Political Rights and the International Covenant on Economic, Social and Cultural Rights etc.) and further statutory provisions and legislative rules guaranteeing religious freedom in the Czech Republic. Major part of the thesis relating to the statutory provisions and legislative rules deals with the act No. 3/2002 Coll., on Freedom of religion and the status of churches and religious societies, as amended. The act No. 3/2002 Coll. constitutes basis of regularization of the freedom of religion in the Czech Republic. Various provisions of the act No. 3/2002 Coll. were subject to review of the Constitutional Court of the Czech Republic due to their unconstitutionality. The second part of the thesis discusses various decisions of the...

The theme of this thesis is history of the knights (later lords) of Vřesovice in the late Middle Ages. The work deals mainly with political and economic role of the family members in the late medieval Bohemia, with special attention to the hussite captain Jakoubek of Vřesovice, who was mainly responisible for family rise. Furthermore, this work tries to answer the question, what happened to the family of Vřesovice since Jakoubek's death until the late Middle Ages, because during the 16th century, knights of Vřesovice belonged to the most powerful aristocratic families in Bohemia. Family members from the times of king George and Jagellonian rulers were not yet reflected by many historians. Fates of individual family members are assessed and placed into historical context. The work deals with property relations of knights of Vřesovice and manifestations of their aristocratic representation. As a whole, the work probes into political, economic, cultural and social life in late medieval northwest Bohemia. Key words: Jakoubek of Vřesovice, gentry, nordwest Bohemia, late Middle ages, 15.-16. century, castles, heraldy