Purpose: Sweden's construction industry is facing great challenges in form of increased housing with the increasing demands on the environment and economy, this combined with the current low unemployment today and many upcoming retirements. To meet these challenges, it requires development and changes which BIM is considered to handle if it is correct performed. 3d planning is an important part of BIM, where it lays the ground for further step in the building process following two steps, production and management. Method: Selected methods of this thesis is a literature review, semi-structured interviews and document analysis. In the literature review writings about, or related to, 3d planning was studied. The interview method gave more detailed information about the problems that planners experience in reality. The document analysis created a deeper understanding of how 3d design work. Findings: The results show that with simple means it is possible to avoid common problems. Which leads to streamline of 3d design and the entire construction process. This in the form of aspects including economy, the environment and sustainable construction. Implications: Development and improvements in 3d design leads to more effective planning which in contributing to more effective construction. Increase of efficiency can now be justified by the savings in the economy and the environment. But visions of development potential in the further step exists today. One step further, for example, be monitoring the working environment in the planning phase. More education in BIM at all levels of the construction industry should create a better understanding of each other and alleviate the communication gaps that currently prevails. Limitations: This thesis is limited to the design phase of the building process conducted with 3d modeling. / Syfte: Sveriges byggbransch står idag inför stora utmaningar i form av ökat bostadsbyggande med allt högre krav på miljö och ekonomi. Detta i kombination med rådande låg arbetslöshet redan idag och många kommande pensionsavgångar. För att möta dessa utmaningar krävs utveckling och förändring, vilket BIM anses klara om det utförs korrekt. 3d projektering utgör en viktig byggsten inom BIM, där den lägger grunden för vidare arbete i byggprocessens följande två steg som är produktion och förvaltning. Metod: Valda metoder för detta examensarbete är litteraturstudie, semistrukturerad intervju och dokumentanalys. I litteraturstudien studerades litteratur som handlar om eller är relaterade till 3d projektering. Intervjumetoden gav djupare information om problematiken som projektörer upplever i verkligheten. Dokumentanalysen skapade en djupare förståelse hur 3d projektering fungerar. Resultat: Studiens resultat visar att det med hjälp av enkla medel går att undvika vanligt förekommande problem inom 3d projektering för att effektiviseras. Dessa enkla medel är främst förbättrad kommunikation, kompetens och förståelse för varandra. Effektivisering av 3d projektering leder till att öka effektiviteten i hela byggprocessen. Detta med besparingar på bland annat ekonomi, miljö, arbetssäkerhet och hållbart byggande. Konsekvenser: Utveckling och förbättringar inom 3d projektering leder till effektivare projektering som i sin bidrar till effektivare byggprocess. Ökning av effektiviteten kan idag motiveras med besparingar inom ekonomi och miljö. Men visioner om utvecklingspotential i vidare steg finns idag. Ett steg längre kan exempelvis vara kontroll av arbetsmiljön redan i projektering. Mer utbildning inom BIM i alla nivåer för byggbranschen bör skapa en bättre förståelse för varandra och mildra de kommunikationsbrister som idag råder. Begränsningar: Detta examensarbete begränsar sig till projekteringsfasen inom byggprocessen som utförs med 3d modellering.

Master of Landscape Architecture / Department of Landscape Architecture/Regional and Community Planning / Howard Hahn / Evolving needs for universities, municipalities, and corporations demand more sustainable and efficient techniques for data management. Geographic Information Systems (GIS) enables decision makers to spatially analyze the built environment to better understand facility usage by running test scenarios to evaluate current efficiencies and identify opportunities for investment. This can only be conducted when data is organized and leveraged across many departments in a collaborative environment. Data organization through GIS encourages interdepartmental collaboration uniting all efforts on a common front. An organized system facilitates a working relationship between the university and the community of Manhattan increasing efficiency, developing sustainable practices, and enhancing the health and safety of Kansas State University and larger community. Efficiency is increased through automation of many current practices such as work requests and routine maintenance. Sustainable practices will be developed by generating self-guided campus tours and identifying area appropriate for bioswales. Lastly, safety will be enhanced throughout campus by increasing emergency response access, determining areas within buildings difficult to reach in emergency situations, and identifying unsafe areas on campus. Evolving needs for universities, municipalities, and corporations demand more sustainable and efficient techniques for data management. Geographic Information Systems (GIS) enables decision makers to spatially analyze the built environment to better understand facility usage by running test scenarios to evaluate current efficiencies and identify opportunities for investment. This can only be conducted when data is organized and leveraged across many departments in a collaborative environment. Data organization through GIS encourages interdepartmental collaboration uniting all efforts on a common front. An organized system facilitates a working relationship between the university and the community of Manhattan increasing efficiency, developing sustainable practices, and enhancing the health and safety of Kansas State University and larger community. Efficiency is increased through automation of many current practices such as work requests and routine maintenance. Sustainable practices will be developed by generating self-guided campus tours and identifying area appropriate for bioswales. Lastly, safety will be enhanced throughout campus by increasing emergency response access, determining areas within buildings difficult to reach in emergency situations, and identifying unsafe areas on campus. Optimizing data management for Kansas State University was conducted in three phases. First, a baseline assessment for facility management at Kansas State University was conducted through discussions with campus departments. Second, case study interviews and research was conducted with leaders in GIS management. Third, practices for geospatial data management were adapted and implemented for Kansas State University: the building of a centralized database, constructing a 3-dimensional routing network, and modeling a virtual campus in 3D.

L'objectif de la thèse est de développer une méthode de modélisation 3D des tunnels canaux en service, afin de les documenter de manière précise. Le levé des structures est effectué en dynamique depuis un bateau, avec un ensemble de caméras au-dessus de l'eau et un sonar pour la partie immergée. La construction du modèle 3D doit combiner des données acquises dans deux milieux différents, en l'absence de signal GPS pour la localisation du système de mesure. L'approche proposée exploite pleinement les capacités du calcul photogrammétrique, à la fois pour construire le modèle 3D de la voûte et pour estimer la trajectoire du bateau, laquelle permet de géoréférencer les profils de points sonar. L'application du procédé en vraie grandeur dans le tunnel de Niderviller a permis d'obtenir un premier modèle 3D. L'analyse de la méthode a mis en jeu une technologie innovante de mesure sonar statique, nécessitant le développement de traitements appropriés. Elle a permis de jauger les capacités du sonar à numériser les canaux, d'évaluer les trajectoires estimées par photogrammétrie et de comparer quantitativement le modèle obtenu à un modèle de référence préalablement construit. / The aim of this thesis is to develop a 3D modeling method for canal-tunnels in service, in order to document them accurately. The survey of the structures is carried out dynamically from a boat, with a set of cameras above the water and a sonar for the submerged part. The construction of the 3D model must combine data acquired in two different environments, in the absence of a GPS signal to locate the measurement system. The proposed approach makes full use of the capabilities of photogrammetric computation, both to build the 3D model of the vault and to estimate the trajectory of the boat, which allows georefencing of sonar point profiles. The application of the process to field test data acquired in the Niderviller tunnel allowed a first 3D model to be obtained. The analysis of the method involved an innovative static sonar measurement technology, requiring the development of appropriate treatments. It enabled to assess the capacity of the sonar for canal surveying, to evaluate the trajectories estimated using photogrammetry and to compare quantitatively the obtained model with a previously constructed reference mode

Orientador: César Augusto Moreira / Resumo: O potencial geológico do Brasil para mineralizações auríferas é mundialmente reconhecido, quer seja pelo seu passado histórico, como por conta do expressivo número de ocorrências, depósitos, minas e as centenas de áreas ativas e inativas distribuídas por todo o país. Na região em que presente estudo foi realizado, já foram detalhados uma série de jazimentos desta natureza, caracterizadas por associações de filões de quartzo e pequenas proporções de óxidos de ferro, pirita e calcopirita. Este trabalho apresenta, portanto, os resultados de um estudo de prospecção geofísica de detalhe realizado a partir da aplicação conjunta dos métodos da Eletrorresistividade e da Polarização Induzida, integrados a análise estrutural. O local estudado consiste numa área potencialmente mineralizada em ouro no Complexo Bossoroca, localizada na zona rural do município de São Sepé (RS). Para obtenção dos dados geofísicos foram realizadas cinco linhas de 400m de comprimento e 10m de espaçamento entre eletrodos, através da técnica de tomografia elétrica em arranjo Schlumberger. O levantamento estrutural, por sua vez, considerou medidas de lineamentos, extraídas a partir de imagem SRTM da área, assim como dados de acamamentos e de fraturas de litotipos pertencente ao Complexo Bossoroca, obtidos a partir de levantamento estrutural sistemático. Os resultados de resistividade não permitiram a definição de zonas mineralizadas, possivelmente devido ao pequeno contraste existente entre a rocha encaixante e ... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: Brazil’s geological potential for auriferous mineralization is recognized worldwide for its historic past, as well as for the number of occurrences, deposits, mines and hundreds of active and inactive areas distributed throughout the country. In the region where the present study was carried out, series of such deposits have already been described, characterized by associations of quartz lodes and small proportions of iron oxides, pyrite and chalcopyrite. This work presents the results of a geophysical prospecting study obtained through the joint application of the DC resistivity and induced polarization methods, integrated to the structural analysis. The studied areas consists of a potentially gold mineralized area in the Bossoroca Complex located in the county of São Sepé (RS). In order to obtain the geophysical data, five lines with 400m in length and 10m of spacing between electrodes were made through the electrical tomography technique in a Schlumberger arrangement. The structural data collecting considered measures of lineaments, extracted from the SRTM image of the area, as well as data of bedding and fractures of lithotypes belonging to the Bossoroca Complex, obtained from a systematic structural data collecting. The results of resistivity did not allow the definition of mineralized zones, possibly due to the small contrast between the rock and the mineralized zone. The chargeability data indicated three zones with high values of load (≥ 4,4 mV / V) located to the eas... (Complete abstract click electronic access below) / Mestre

[Truncated abstract] The aim of visual recognition is to identify objects in a scene and estimate their pose. Object recognition from 2D images is sensitive to illumination, pose, clutter and occlusions. Object recognition from range data on the other hand does not suffer from these limitations. An important paradigm of recognition is model-based whereby 3D models of objects are constructed offline and saved in a database, using a suitable representation. During online recognition, a similar representation of a scene is matched with the database for recognizing objects present in the scene . . . The tensor representation is extended to automatic and pose invariant 3D face recognition. As the face is a non-rigid object, expressions can significantly change its 3D shape. Therefore, the last part of this thesis investigates representations and matching techniques for automatic 3D face recognition which are robust to facial expressions. A number of novelties are proposed in this area along with their extensive experimental validation using the largest available 3D face database. These novelties include a region-based matching algorithm for 3D face recognition, a 2D and 3D multimodal hybrid face recognition algorithm, fully automatic 3D nose ridge detection, fully automatic normalization of 3D and 2D faces, a low cost rejection classifier based on a novel Spherical Face Representation, and finally, automatic segmentation of the expression insensitive regions of a face.

Cette thèse met en avant une démarche originale, celle de faire cohabiter l'utilisation d'une technologie moderne, au sein d'une étude archéologique conventionnelle centrée sur l'architecture grecque. L'utilisation de la modélisation 3D dans ce projet doctoral nous amène indubitablement à explorer de nouvelles problématiques en archéologie grecque. Pour ce faire, une réflexion sera menée sur les apports de cette technologie aux sciences archéologiques. En effet, la restitution d'un édifice antique en 3D implique des questionnements sur la réalité virtuelle créée. La modélisation 3D se fonde sur du matériel archéologique partiel altéré par le temps. C'est pourquoi il est nécessaire de prendre du recul face à une image 3D qui peut idéaliser une réalité archéologique. Notre étude s'appliquera aussi à apporter des solutions permettant de remédier à ces complications liées à la restitution virtuelle. De plus, la restitution 3D d'un édifice antique n'est pas une fin en soi. En d'autres termes, cette technologie doit par son approche intuitive apporter une nouvelle façon d'appréhender les questions qui touchent à la construction des édifices antiques. À commencer par les méthodes de constructions ou encore la faisabilité architecturale...etc. Dans un même temps, nous mènerons un examen architectural et archéologique dans le but de proposer une étude qui soit équilibrée et qui puisse être réutilisée par la recherche archéologique. Nos objectifs sont multiples et cette étude fait le vœu d'être ambitieuse. Pour cela, cette étude s'attellera à éviter l'écueil de proposer une approche ayant un cadre trop restrictif. C'est pourquoi nous envisageons de préférence une étude qui associera plusieurs groupes d'édifices aux fonctions différentes. De ce fait, en tenant compte d'un maximum de situations et de réalités archéologiques, notre examen gagnera en représentativité, tout comme cela lui assurera une probabilité plus grande d'être réutilisé dans la recherche pour d'autres applications liées à la restitution 3D. Cette thèse est aussi une occasion d'évoquer les questions liées à la valorisation du patrimoine culturel. Ce thème sera aussi abordé, car le partage du savoir ne doit pas seulement être destiné aux initiés, mais aussi auprès du grand public. Il s'agit là d'une mission essentielle que l'archéologie se doit de mener à bien. / This thesis puts forward a novel approach who will make cohabit together the use of a modern technology in a conventional archaeological study focused on Greek architecture. The use of 3D modeling in this doctoral project leads undoubtedly to explore new issues in the Greek archeology. To do this, we will consider to the benefits of this technology to archaeological sciences. Indeed, the restitution of an ancient building in 3D, involves questions on the virtual reality that created. 3D modeling is based on the archaeological material altered by the time. That is why, it is necessary to take a step back on a 3D picture that can idealize an archaeological reality. Our study will also apply to provide solutions to overcome these complications of the virtual restitution. Moreover, the 3D rendition of an ancient building is not an end in itself. In other words, this technology must provide a intuitive approach and a new way to understand the issues that affect at the construction of ancient buildings. Starting with the construction methods or architectural feasibility ... etc.. At the same time, we will conduct an architectural and archaeological examination in order to propose a study that is balanced and that can be reused by archaeological research. Our goals are many and this study wants to be ambitious. For this, this study will strive to avoid the pitfall of proposing an approach that is too restrictive. That is why we plan to combine preferably a study several groups of buildings with different functions. Therefore, taking into account a maximum of archaeological situations our study will be more representative, as this will ensure it a greater likelihood of being reused in the archeological studies. This thesis is also an opportunity to discuss issues related to the promotion of cultural heritage. This topic will also be addressed because the sharing of knowledge should not be accessible only to insiders, but it must also be affordable for the general public. This is an essential task that archeology must carry.

[pt] Esta dissertação tem por objetivo a implementação de uma ferramenta numérica para avaliação do fluxo transiente 3D saturado-não saturado em barragens de terra e enrocamento, baseado no método dos elementos finitos e no programa GEOFLUX implementado por Machado Jr. (2000) para análise de problemas 2D. Nesta nova versão, foram incluídos elementos triangulares de 3 nós para análises 2D e elementos tetraédricos de 4 nós para análises 3D. Implementam-se também subrotinas que oferecem a possibilidade de variação das condições de contorno com o tempo. A equação de Richards é solucionada considerando a formulação mista e o método iterativo de Picard Modificado para solução do sistema de equações não- lineares. Para a solução do sistema de equações utiliza-se um armazenamento especial para matrizes esparsas associado com o método do gradiente bi-conjugado, tornando o processo muito rápido, mesmo em sistemas de grande porte. Utilizam- se dois modelos para representar as curvas características: o modelo exponencial proposto por Srivastava e Yeh (1991) e o modelo proposto por van Genuchten (1980). O programa computacional desenvolvido (GEOFLUX3D) foi aplicado na análise de fluxo na barragem de enrocamento de Gouhou, China, e na barragem de terra Macusani, Peru. Os resultados numéricos indicam a necessidade de análises numéricas 3D em barragens situadas em vales estreitos, onde os efeitos de geometria nas condições de fluxo são significativos e não podem ser ignorados. / [en] The main objective of this thesis is to implement a numerical tool for the evaluation of 3D saturated / unsaturated transient flow through earth and rockfill dams with basis on the finite element method and a computer program written by Machado Jr. (2000) for analysis of similar 2D flow problems. In the 3D version, developed in this thesis, four-nodes tetrahedral elements were implement as well as special subroutines that make possible to vary in time the boundary conditions. The Richards` equation is solved through a mixed formulation, for the solution of the non-linear system of equations a Modified Picard`s method is employed. A special algorithm is used to store the sparse matrices which, in association with the bi-conjugated gradient method, rend the solver computationally very efficient, even for a large number of equations. Two different models were used to represent the characteristic curves: the exponential curve proposed by Srivastava and Yeh (1991) and the formulation suggested by van Genuchten (1980). The improved computer program, thereafter named GEOFLUX3D, was then applied for flow analysis of the Gouhou rockfill dam (China) and the Macusani earth dam (Peru). Numerical results point out that 3D numerical analyses are necessary for dams situated in narrow valleys, where the influence of the terrain geometry on the flow conditions are quite significant and cannot be just ignored.

Made available in DSpace on 2015-02-24T19:48:35Z (GMT). No. of bitstreams: 1 YoeARP_Da_ capa_ ate_pag32.pdf: 4563485 bytes, checksum: 2bb58a8570cdf436e302b817c725d549 (MD5) Previous issue date: 2008-03-31 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior / In this beginning of the XXI century, the Geology moves for new ways that demand a capacity to work with different information and new tools. It is within this context that the analog characterization has important in the prediction and understanding the lateral changes in the geometry and facies distribution. In the present work was developed a methodology for integration the geological and geophysical data in transitional recent deposits, the modeling of petroliferous reservoirs, the volume calculation and the uncertainties associate with this volume. For this purpose it was carried planialtimetric and geophysics (Ground Penetrating Radar) surveys in three areas of the Parna?ba River. With this information, it was possible to visualize the overlap of different estuary channels and make the delimitation of the channel geometry (width and thickness). For three-dimensional visualization and modeling were used two of the main reservoirs modeling software. These studies were performed with the collected parameters and the data of two reservoirs. The first was created with the Potiguar Basin wells data existents in the literature and corresponding to A?u IV unit. In the second case was used a real database of the Northern Sea. In the procedures of reservoirs modeling different workflows were created and generated five study cases with their volume calculation. Afterwards an analysis was realized to quantify the uncertainties in the geological modeling and their influence in the volume. This analysis was oriented to test the generating see and the analogous data use in the model construction / Neste in?cio do s?culo XXI a Geologia transita por novos caminhos que demandam uma capacidade crescente de trabalhar com informa??es de naturezas variadas, assim como a aplica??o de novas ferramentas. ? dentro desse contexto que a caracteriza??o de an?logos recentes tem se tornado importante para o entendimento e predi??o das mudan?as laterais na geometria e na distribui??o dos corpos e f?cies reservat?rio. No presente trabalho foi desenvolvida uma metodologia de integra??o de dados geol?gicos e geof?sicos de dep?sitos transicionais recentes, em ambiente tridimensional, para serem empregados como subs?dio na modelagem de reservat?rios petrol?feros e estudada a influ?ncia dos mesmos no c?lculo de volume. Para esta finalidade foram realizados levantamentos planialtim?tricos e de geof?sica rasa GPR em tr?s ?reas da desembocadura do Rio Parna?ba. Com as informa??es obtidas foi poss?vel visualizar a superposi??o de diferentes gera??es de canais estuarinos e realizar a delimita??o da geometria do canal atrav?s dos par?metros de largura e espessura. Para a visualiza??o e modelagem tridimensional foram empregados dois dos principais softwares de modelagem de reservat?rios. Este trabalho foi realizado com os par?metros coletados e os dados de dois reservat?rios. O primeiro foi criado com dados de po?os da Bacia Potiguar existentes na literatura e correspondentes a unidade A?u IV. J? no segundo caso foi empregada uma base de dados reais de um modelo da regi?o do mar do norte. Nos procedimentos de modelagem dos reservat?rios foram criadas diferentes rotinas de trabalho e gerados cinco casos de estudo com seus respectivos c?lculos de volumes. Em seguida, foi realizada uma an?lise para quantificar as incertezas referentes ? modelagem geol?gica e a influ?ncia delas no volume. Esta an?lise foi orientada a testar a semente geradora e os dados de an?logos empregados na constru??o do modelo

De senaste åren har implementeringen av building information modeling(BIM) i anläggningsbranschen trappats upp efter att den svenska regeringen under 2015 beslutat att Trafikverket i större utsträckning ska nyttja de digitala möjligheterna med BIM. Trafikverket i form av både beställare och förvaltare av det statliga vägnätet, är en stor aktör i den svenska anläggningsbranschen och konstaterar att kravställningen mot övriga branschen är centralt för att driva utvecklingen och användandet av konceptet BIM. En sådan övergång från ett ritningsbaserat till ett objektbaserat arbetssätt kommer att påverka hela den svenska anläggningsbranschen. Målbilden är att ur ett livscykelperspektiv kunna hantera all information om anläggningen med hjälp av 3D-data. Ska de uppnå det målet krävs det i något skede att den befintliga anläggningen modelleras upp i konceptet BIM En metod som används världen över för 3D-dokumentation av komplexa objekt och miljöer är tekniken terrester laserskanning. Resultatet av en skanning är omfattande med låg mätosäkerhet, vilket lämpar sig väl med framställandet av 3D-modeller. Studien primära syfte är att utifrån resultatet från en skanning undersöka vilka skillnader det finns mellan 3D-modeller beroende på val av mätmetod. Först gjordes en nulägesanalys i form av en litteraturstudie för att kunna erhålla ett aktuellt resultat och placera studien i rätt kontext. Därefter framställdes två 3D-modeller av samma objekt, med hjälp av två olika mätmetoder som sedan jämfördes för att kunna identifiera vilka skillnader mellan modellerna. Resultatet visar att valet av mätmetod påverkade resultatet på 3D-modellen där terrester laserskanning som mätmetod kunde bidra med att förbättra kvalitén på 3D-modellen. Däremot fanns det även områden där mätmetoderna kunde komplettera varandra för ett ännu bättre resultat. / In recent years, the implementation of building information modeling (BIM) in the Swedish civil engineering industry has increased. This is due to directives from the government stating that the Swedish Transport Administration (Trafikverket), in greater occurrence, will benefit from the digital possibilities with the BIM concept. Trafikverket is the government agency responsible for the long-term planning and management of public roads, construction in the infrastructure such as tunnels and bridges, and has great influence in the Swedish civil engineering industry. They claim that the key to enhance the use and development of BIM is to raise their demands towards the rest of the industry. Transitioning from a drawing-based to an object-based approach will affect the entire industry. The idea is to be able to handle all the information in 3D-data and the BIM concept throughout the entire life cycle of the construction. To reach that ambition, the already-built constructions need to be represented as 3D-models in terms of being a part of the BIM concept. Terrestrial laser scanning is a method of measurement that is being used worldwide for 3D-documentation of complex objects and environments. The result of a scan is comprehensive with low uncertainty of measurement; therefore the method is well suited to assist in the creation of 3D-models. The primary aim of the study is to examine the differences between 3D-models, depending on the measurement method that was used to create them. An analysis of the current situation in these fields-of-study was made by a literature study to place this thesis in its proper context. Although the two 3D-models were the same exact object, they were created using two different methods of measurement. The models were compared to identify the differences between them. The study unveils that the choice of measurement method influences the results of the 3D-model, where the terrestrial laser scanning method could help to improve the quality of the final product. On the other hand, there were areas where the two methods of measurement could complement each other for even better results.

Orientador: Ricardo Aparicio / Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Química / Made available in DSpace on 2018-08-24T05:53:06Z (GMT). No. of bitstreams: 1 Reis_MarceloAugustodos_D.pdf: 42698206 bytes, checksum: fa5cd41ff5c44a71b42dd07db4a8fd79 (MD5) Previous issue date: 2013 / Resumo: Neste trabalho de tese, o problema da caracterização estrutural de proteínas foi abordado de maneira contextualizada e com um viés em modelagem computacional utilizando vínculos experimentais obtidos com a técnica de espalhamento de raios X a baixos ângulos (SAXS, Small-Angle X-ray Scattering). Parte das pesquisas foram concentradas na caracterização estrutural da proteína SurE de Xylella fastidiosa (XfSurE) por técnicas experimentais e computacionais. Estudos estruturais da XfSurE realizados com a técnica de SAXS apontaram para um arranjo tetramérico da enzima apo e, do nosso conhecimento, foi a primeira estrutura em solução descrita na literatura para esta família de proteínas. Quando associada às técnicas computacionais ¿ como, por exemplo, análise de modos normais de vibração¿a interpretação das análises por SAXS foi realçada. Neste caso, o vínculo experimental imposto pela curva I(q) possibilitou que uma estrutura em solução fosse modelada apenas com o uso de um único modo normal, cujo efeito estaria relacionado com as possíveis transições alostéricas de XfSurE. Em outra frente de trabalho, um novo programa denominado SAXSTER foi desenvolvido. SAXSTER tem a habilidade de gerar modelos estruturais mais prováveis para uma proteína-alvo a partir de alinhamentos ótimos obtidos por threading e de estruturas similares identificadas em um banco de dados, com o auxílio de SAXS. A partir dos dados de entrada, é realizada uma busca no Protein Data Bank para que a estrutura da proteína-alvo possa ser predita. O programa foi testado para 553 proteínas não redundantes. Foi demonstrado que SAXSTER pode melhorar consistentemente o resultado global da classificação dos alinhamentos, com p-valores que variam de 10 a 10. De acordo com TM-score médio, conclui-se que SAXSTER tende a melhorar o desempenho preditivo conforme a estrutura da proteína-alvo se afasta da forma globular / Abstract: In this work, the protein structure problem was approached from two different perspectives: from the computational modeling to the experimental data mainly collected by Small-Angle X-ray Scattering technique (SAXS) whose data were also used as constraint for modelling. Part of the research was focused on the structural characterization of the protein SurE of Xylella fastidiosa (XfSurE) by experimental and computational techniques. Structural studies of XfSurE performed by SAXS technique indicated a tetrameric arrangement of the apo enzyme and to our knowledge, this was the first solution structure of a SurE protein described in the literature. When combined with computational techniques ¿ for instance, normal mode analysis ¿ the interpretation of SAXS analysis was enhanced. In that case, the experimental constraints imposed by the I(q) curve allowed to reach a new structure model that fits the SAXS profile using only a single normal mode. This effect would be associated with the possible allosteric transitions of the XfSurE. It was also developed a new program called SAXSTER (SAXS-assisted multi-source ThreadER). SAXSTER has the ability to generate more likely structural models for the target protein from optimal alignments obtained by threading and similar structures identified in the Protein Data Bank aided by SAXS. The program was tested on 553 nonredundant proteins. It was shown that SAXSTER can consistently improve the overall classification of the alignments, with p-values ranging from 10 to 10. According to average TM-score, a more promising use of the SAXSTER algorithm would be to improve the template recognition results for protein whose structure is more rod-like than globular-like ones / Doutorado / Físico-Química / Doutor em Ciências