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Hållbara materialkonstruktioner med hjälp av biomimicrySjöqvist, Jennie January 2020 (has links)
Vi behöver minska vår materialkonsumtion, idag gör vi av med mer resurser än vad vi har tillgång till. I den här studien har först en materialkonstruktion tagits fram och därefter ett produktkoncept för konstruktionen. För att ta fram materialkonstruktionen har biomimicry använts. Biomimicry är designmetoder för att lösa designproblem med inspiration från naturen. Naturen använder sig av så lite material som möjligt. Materialkonstruktionen är inspirerad av växtceller. Konstruktionen har två hierarkier som går i två olika riktningar, en riktning som går längs med och en riktning som går i djupled.För att hitta ett produktkoncept för materialkonstruktionen har material driven design (MDD) använts. MDD är en experimentell metod för att lära känna ett material och förstå dess användningsområde. Produktkonceptet är en stapelbar pall.För att minska på resurser används 3d-printning. 3d-printning är en additiv teknik och minskar på så sätt materialåtgång. Dessutom kan allt material lätt återanvändas eftersom det bara behövs ett material.Produkten kan produceras lokalt vilket minskar på transporter. PLA har använts som material i den här studien. / We need to reduce our material consumption, today we are wasting more resources than we have access to. In this study, a material construction was first developed and then a product concept for the construction. Biomimicry has been used to develop the material construction. Biomimicry are design methods for solving design problems with inspiration from nature. Nature uses as little material as possible. The material construction is inspired by plant cells. The construction has two hierarchies that go in two different directions.To find a product concept for the construction, material driven design (MDD) has been used. MDD is an experimental method used to get to know a material and understand its application. The product concept is a stackable pallet.To reduce resources, 3D printing is used. 3D printing is an additive technology and thus reduces material consumption. In addition, all material can be easily reused as only one material is needed.The product can be produced locally, which reduces on transport. PLA has been used as material in this study.
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Electric Field Driven Migration and Separation in the MicroenvironmentJanuary 2020 (has links)
abstract: Novel electric field-assisted microfluidic platforms were developed to exploit unique migration phenomena, particle manipulation, and enhanced droplet control. The platforms can facilitate various analytical challenges such as size-based separations, and delivery of protein crystals for structural discovery with both high selectivity and sensitivity. The vast complexity of biological analytes requires efficient transport and fractionation approaches to understand variations of biomolecular processes and signatures. Size heterogeneity is one characteristic that is especially important to understand for sub-micron organelles such as mitochondria and lipid droplets. It is crucial to resolve populations of sub-cellular or diagnostically relevant bioparticles when these often cannot be resolved with traditional methods. Herein, novel microfluidic tools were developed for the unique migration mechanism capable of separating sub-micron sized bioparticles by size. This based on a deterministic ratchet effect in a symmetrical post array with dielectrophoresis (DEP) for the fast migration allowing separation of polystyrene beads, mitochondria, and liposomes in tens of seconds. This mechanism was further demonstrated using high throughput DEP-based ratchet devices for versatile, continuous sub-micron size particle separation with large sample volumes. Serial femtosecond crystallography (SFX) with X-ray free-electron lasers (XFELs) revolutionized protein structure determination. In SFX experiments, a majority of the continuously injected liquid crystal suspension is wasted due to the unique X-ray pulse structure of XFELs, requiring a large amount (up to grams) of crystal sample to determine a protein structure. To reduce the sample consumption in such experiments, 3D printed droplet-based microfluidic platforms were developed for the generation of aqueous droplets in an oil phase. The implemented droplet-based sample delivery method showed 60% less sample volume consumption compared to the continuous injection at the European XFEL. For the enhanced control of aqueous droplet generation, the device allowed dynamic triggering of droplets for further improvement in synchronization between droplets and the X-ray pulses. This innovative technique of triggering droplets can play a crucial role in saving protein crystals in future SFX experiments. The electric field-assisted unique migration and separation phenomena in microfluidic platforms will be the key solution for revolutionizing the field of organelle separation and structural analysis of proteins. / Dissertation/Thesis / Doctoral Dissertation Chemistry 2020
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A Platform Technology for Concurrent 3D Printing of Decellularized Matrices and Polycaprolactone for Regeneration in Homogenous and Heterogeneous TissuesGruber, Stacey M. S. 15 October 2020 (has links)
No description available.
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Návrh variantní výrobní technologie oběžného kola ventilátoru / Variant production technology of a fan impellerMacháček, Marek January 2021 (has links)
The thesis considers a change in the manufacturing technology of a fan impeller from welding to 3D printing. The wish of the manufacturer was to investigate if such a change is possible and financially profitable and decide on a further approach to manufacturing. Models were created using information from the manufacturer and using them, conditions for manufacturing the impeller in the 1:1 ratio were derived. Based on the new technological process and the experience from prints a new price calculation for the fan impeller using 3D printing was created.
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3D Printed Patient Specific Surgical Guide for Spine Registration During Minimally Invasive SurgeryHujaleh, Iffa 17 November 2021 (has links)
Minimally invasive spine surgery (MISS) has proven to be advantageous over traditional open
surgery as it minimizes the likelihood of tissue damage and infections. During MISS, surgeons
create small incisions to allow access to the surgery site, however, opting for smaller incisions
decreases the surgeon’s field of vision. To compensate, surgeons rely on preoperative and
intraoperative ionizing imaging technologies for guidance.
Conventional localization of the spine, registration of digital images to the patient during surgery,
depends heavily on the surgeon’s anatomical knowledge and their experience. Preoperative
images are typically created using 3D technology while intraoperative images use 2D technology.
While the integration of preoperative 3D images and intraoperative 2D images can provide
valuable assistance, patient’s preoperative and intraoperative positions do not coincide leading to
additional use of ionizing imaging.
The objective of this research was to propose a workflow that assists with image registration for
MISS. The main component of the workflow was the creation of a script that automatically
generates patient-specific digital guides, which will then be manufactured, to align the patient’s
intraoperative and preoperative body position. By aligning the patient’s positions, the 3D printed
surgical guide serves as a shared feature between the preoperative digital image and the actual
patient. This allows for the intraoperative image to be registered to the preoperative image more
accurately. Additionally, the guide acts as an attachment site for any additional instrument
guides/supports.
The surgical guide generating script utilizes the skin contour of patient’s torso region, extracted
from medical images, to automatically produce the guide’s horizontal and vertical components.
Adjustments are made to the components using CAD software before proceeding to
manufacturing, via 3D printing, and assembly of the guide. To validate the workflow, more
specifically the script’s ability to automatically generate surgical guides that fit over the patient’s
back, a guide was created for a mannequin. The maximum gap between the mannequin and the
horizontal components was 0.8 cm and 1.5 cm for the vertical component.
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Passive Control of Fiber Orientation in Direct Ink Writing 3D PrintingKhatri, Nava Raj 08 1900 (has links)
Several active methods, which requires external control systems and moving parts, have been developed to control the fiber orientation during 3D printing. Active mechanisms like rotating nozzle, impeller, and magnetic field have been integrated to realize complex internal fiber structures. In this study, instead of using active methods, I investigate a passive method for controlling the fiber orientation without any moving parts or additional mechatronics added in the printing process. Composites of polydimethylsiloxane (PDMS) and glass fibers (GF) are 3D printed. Channels, such as helicoid, are designed and integrated to guide the ink flow and passively result in different pre-alignment of fibers before the ink flow into narrow nozzle space. While passing through the designed channels, the fibers orient due to the shear between channel walls and the ink. The effect of helicoids with different pitch sizes are investigated via mechanical experiments, microstructural analysis, and numerical simulations. The results show that both surface to volume ratio and helix angle of the channel affect pre-alignment of fiber orientation at the entry of nozzle. The internal fiber structures lead to enhanced and tunable mechanical properties of printed composites. Pitch size 7-9 mm (helix angle of 7.92- 10.15o) is found to be optimal for the 3D printed PDMS-GF composites. Stiffness and strength can be tuned up to 77.6% and 47.8%, respectively, compared with the case without helicoid channel. Channels of parallel holes, parallel holes with taper end and gradually changing pitch helicoids are experimentally tested, showing further enhancement in mechanical properties.
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3D-printing : För effektivisering av produkterBörjesson, Christopher January 2021 (has links)
In this report, my work on 3D-printing will be presented. This project is what constitutes my examination project in the education of industrial design engineering. 3D-printers are tools that have undergone great development in recent years. Through this development, the machines have become increasingly accessible to private individuals thanks to reduced prices, easyer use and higher quality. Through an increased use of the tool on a more private level, new opportunities are created for how we manufacture products, as well as how our attitude to its components are viewed. The purpose of the work was to investigate how 3D-printing can be used to create more efficient and sustainable products with a focus on users, manufacturers and the environment. The goal was to develop an approach to utilize the function of a 3D-printer in a way that contributes to higher sustainability and efficiency, where the end result should contribute to this without forcing the user to make any decisive sacrifices. The work has been carried out with a three-part process, divided into the phases Inspiration, Ideation and implementation, which together constitute an iterative design process. Initially in the inspiration phase, inspiration was created for the work with the help of a literature study, theory collection and a context analysis. Then began the ideation phase, whose purpose was to start creating ideas and conceptualize the inspiration that has previously been collected in the inspiration phase. To implement these ideas and concepts, the implementation phase was carried out to achieve a more completed and implemented concept. The work resulted in the concept TonePrint. TonePrint is a speaker and a pair of headphones that work together in a form of ecosystem to make the interaction smoother for the user when changing audio source. The product TonePrint is a product that the user 3D-prints by oneself. This contributes to a more efficient and sustainable product as well as production. The product is designed in a way that enables the user to configure the product based on their own needs, which contributes to increased personalization. It allows the user to reuse components from previous devices that would otherwise be discarded, or select components based on their own liking and taste. / I den här rapporten kommer mitt arbete rörande 3D-printeing presenteras. Det här projektet är det som utgör mitt examensarbete i utbildningen högskoleingenjör inom teknisk design. 3D-printers är verktyg som har genomgått stor utveckling de senaste åren. Genom den här utvecklingen har maskinerna blivit allt mer tillgängliga för privatpersoner tack vare lägre priser, smidigare användning och högre kvalitet. Genom en ökad användning av verktyget på mer privata plan skapas nya möjligheter för hur vi tillverkar produkter, samt hur vi ser på produkter och dess uppbyggande komponenter. Syftet med arbetet var att undersöka hur 3D-printing kan användas för att skapa mer effektiva och hållbara produkter med fokus på användare, tillverkare och miljön. Målet var att ta fram ett tillvägagångssätt att nyttja de egenskaper en 3D-printer medför på ett sätt som bidrar till en högre hållbarhet och effektivitet, där det slutliga resultatet ska bidra till detta utan att tvinga användaren att göra några avgörande uppoffringar. Arbetet har genomförts med en tre delad process, indelad i faserna Inspiration, Ideation och implementation som tillsammans utgör en iterativ designprocess. Initialt i inspirationsfasen skapades inspiration för arbetet med hjälp av en litteraturstudie, teoriinsamling samt en kontextanalys. Därefter påbörjades ideationsfasen, vars syfte var att börja skapa idéer och konceptualisera den inspirationen som tidigare blivit insamlad i inspirationsfasen. För att implementera dessa idéer och koncept utfördes implementationsfasen för att nå ett mer färdigställt och förverkligat koncept. Arbetet resulterade i konceptet TonePrint. TonePrint är en högtalare och ett par hörlurar som samverkar i ett form av ekosystem för att göra interaktionen smidigare för användaren vid byte av ljudkälla. Produkten TonePrint är en produkt som användaren själv 3D-printar. Detta bidrar till en mer effektiv och hållbar produkt samt produktion. Produkten är utformad på ett sätt som möjliggör för användaren att konfigurera produkten utifrån eget behov vilket bidrar till en ökad personalisering. Det möjliggör för användaren att återanvända komponenter från tidigare enheter som annars skulle slängas, eller välja komponenter utifrån eget tycke och smak.
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Inovace 3D tiskárny typu Rep Rap / Innovation of the Rep Rap 3D PrinterZítka, Lukáš January 2017 (has links)
The present Master thesis is focused on innovation and verification of the functionality of a 3D RepRap. The theoretical part of the thesis characterizes individual additive technologies. The practical part is focused on the design of the technical modifications of the printer in order to achieve the quality of the printing, while the current 3D printer design is compared with the innovative solution. The practical part tests the setting of print parameters, various materials for 3D printing and necessary finishing operations. The thesis is completed
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Píst zážehového motoru pro 3-D tisk / Piston of a spark-ignition engine for 3-D printingZelko, Lukáš January 2019 (has links)
The goal of the thesis was to design a piston manufactured by conventional method and subsequently adjusted one for additive manufacturing. Beside the designs, thermo-structural model was created for both pistons, considering maximal loading of the engine. Analysis evaluation showed the possibility of further application of the new technology in comparison to current one, within automotive industry.
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Topologické optimalizace v technické praxi / Topological optimization in technical practiceMazoch, Jan January 2019 (has links)
Master’s thesis deals with an issue of 3D printing and of using a topological optimization for editing a shape of a 3D printed product. First part of this thesis provides a general description of a subtractive manufacturing technology, specifically its use in CNC milling machines, and of an additive manufacturing technology which is used in 3D printing. Second part of this thesis describes the topological optimization per se and specific methods which are used in the topological optimization. In the third and the fourth part of this thesis, topological optimization modules of software Ansys and SolidWorks are described. In the fifth part of this thesis, the topological optimization capabilities for 3D printed product on a specific embodiments of a design lightning and a cross-beam are demonstrated.
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