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Κατασκευή αυτόματου συστήματος φόρτισης μπαταριών με μικροϋπολογιστικό σύστημα ειδικού σκοπούΛουριδάς, Κωνσταντίνος 17 July 2014 (has links)
Στην παρούσα διπλωματική εργασία γίνεται επισκόπηση των βασικών τεχνολογιών επαναφορτιζόμενων και μη μπαταριών και στη συνέχεια μέσω της τεχνολογίας ενσωματωμένων συστημάτων παρουσιάζεται η υλοποίηση με λογισμικό πάνω σε έναν μικροελεγκτή ARM7 της Analog Devices, ενός φορτιστή μπαταριών τύπου NiMH. / In the following diploma thesis appears an overview of basic technologies of the rechargeable and non rechargeable batteries and then through technology of embedded systems shows the implementation with software on a microcontroller ARM7 of Analog Devices, of a NiMH battery charger.
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Μελέτη και κατασκευή διάταξης φορτισης ηλεκτροχημικών συσσωρευτών για ηλεκτροκίνητο όχημαΣτυλογιάννης, Αχιλλέας 16 May 2014 (has links)
Η παρούσα διπλωματική εργασία πραγματεύεται τη θεωρητική ανάλυση και προσομοίωση διάταξης φόρτισης ηλεκτροχημικών συσσωρευτών για ηλεκτροκίνητο όχημα καθώς και την κατασκευή της για την πειραματική απόδειξη της ορθής λειτουργίας της. / This thesis deals with the theoritical analysis and simulation of power supply for electric vehicle and the construction for experimental evidence for the proper functioning of the power supply.
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Reprogramação fenotípica por excesso de glicocorticoides: participação de micro-RNAs no desenvolvimento hepático e possíveis repercussões na vida adulta. / Programming by glucocorticoid excess: actions of miRNAs on hepatic development and outcome.Pantaleão, Lucas Carminatti 24 February 2015 (has links)
Avaliamos o efeito da RCIU induzida por glicocorticoides sobre a regulação da expressão de miRNAs no fígado de ratos albinos. Animais expostos intrauterinamente à dexametasona apresentaram menor peso ao nascer, fígados relativamente menores dos que os observados em animais controle e menores concentrações hepáticas de PCNA. Em longo prazo, os animais DEX desenvolveram distúrbios metabólicos caracterizados por intolerância à glicose e maior potencial gliconeogênico no desmame e na vida adulta. Ao avaliarmos o perfil de miRNAs no fígado, detectamos aumento da expressão de todo o cluster do miR-322 no período perinatal, com menor conteúdo de alvos preditos desses transcritos (AKT3, CCND1 e INSR). A superexposição ao miR-322-5P reduz a taxa de proliferação em linhagens celulares de hepatocarcinoma e a expressão dos alvos observados no fígado dos animais estudados. Propomos um link entre a expressão aberrante do miR-322-5P e a reduzida taxa de proliferação detectada no tecido hepático em desenvolvimento, contribuindo para o estabelecimento do fenótipo em longo prazo. / We evaluated the effects of glucocorticoid induced IUGR on the expression of miRNA on Wistar rat livers. Dexamethasone (DEX) treated animals were lighter and had smaller liver weight:body weight ratio when compared to control animals. Furthermore, liver PCNA expression was downregulated, sugesting a reduction on cell proliferation rate. In the long term, DEX animals developed metabolic disturbances such as glucose intolerance e increased gluconeogenesis rate in a fast state. The analysis of miRNA expression profile showed an upregulation of miR-322 cluster on perinatal period, together with a downregulation of three putative targets: Akt3, CCND1 and INSR. Later, we used in vitro studies to prove that overexpression of miR-322-5P arrests cell cycle and impairs proliferation of HEPG2 cells as well as it downregulates the predicted targets. Based on this data, we suggest a link between overexpression of miR-322-5P and impaired proliferation rate on the developing liver, which affects the phenotype in the long term.
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Reprogramação fenotípica por excesso de glicocorticoides: participação de micro-RNAs no desenvolvimento hepático e possíveis repercussões na vida adulta. / Programming by glucocorticoid excess: actions of miRNAs on hepatic development and outcome.Lucas Carminatti Pantaleão 24 February 2015 (has links)
Avaliamos o efeito da RCIU induzida por glicocorticoides sobre a regulação da expressão de miRNAs no fígado de ratos albinos. Animais expostos intrauterinamente à dexametasona apresentaram menor peso ao nascer, fígados relativamente menores dos que os observados em animais controle e menores concentrações hepáticas de PCNA. Em longo prazo, os animais DEX desenvolveram distúrbios metabólicos caracterizados por intolerância à glicose e maior potencial gliconeogênico no desmame e na vida adulta. Ao avaliarmos o perfil de miRNAs no fígado, detectamos aumento da expressão de todo o cluster do miR-322 no período perinatal, com menor conteúdo de alvos preditos desses transcritos (AKT3, CCND1 e INSR). A superexposição ao miR-322-5P reduz a taxa de proliferação em linhagens celulares de hepatocarcinoma e a expressão dos alvos observados no fígado dos animais estudados. Propomos um link entre a expressão aberrante do miR-322-5P e a reduzida taxa de proliferação detectada no tecido hepático em desenvolvimento, contribuindo para o estabelecimento do fenótipo em longo prazo. / We evaluated the effects of glucocorticoid induced IUGR on the expression of miRNA on Wistar rat livers. Dexamethasone (DEX) treated animals were lighter and had smaller liver weight:body weight ratio when compared to control animals. Furthermore, liver PCNA expression was downregulated, sugesting a reduction on cell proliferation rate. In the long term, DEX animals developed metabolic disturbances such as glucose intolerance e increased gluconeogenesis rate in a fast state. The analysis of miRNA expression profile showed an upregulation of miR-322 cluster on perinatal period, together with a downregulation of three putative targets: Akt3, CCND1 and INSR. Later, we used in vitro studies to prove that overexpression of miR-322-5P arrests cell cycle and impairs proliferation of HEPG2 cells as well as it downregulates the predicted targets. Based on this data, we suggest a link between overexpression of miR-322-5P and impaired proliferation rate on the developing liver, which affects the phenotype in the long term.
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Traveling density variations in partially ionized gases.January 1964 (has links)
No description available.
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Expression des ABC-Transporters ABCA3 in Zellen der physiologischen Hämatopoese und in maligne transformierten lymphatischen Zellen / ABC-transporter ABCA3 expression in normal hematopoiesis and in transformed lymphoid cellsCorsham, Sabrina F. E. 07 July 2008 (has links)
No description available.
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Traitement de la matière active d’accumulateurs Ni-Cd en fin de vie par couplage électrolixiviation/électrodéposition / Treatment of active matter coming from end-of-life Ni-Cd batteries by coupling elctroleaching/electrowinningHazotte, Claire 05 December 2014 (has links)
Ce mémoire porte sur le développement d'un protocole d'extraction sélective de métaux présents dans les accumulateurs Ni-Cd en fin de vie. Classiquement, les procédés hydrométallurgiques appliqués à ce type de solides comportent de nombreuses étapes dont les principales sont la lixiviation et la récupération du métal par électrolyse. Le procédé utilisé permet le couplage des opérations d'Electrolixiviation et d'Electrodéposition (noté E/E) au sein d'une même cellule. La technique est basée sur la lixiviation de la matière active des accumulateurs Ni-Cd par les protons générés à l'anode, les cations lixiviés (Co2+, Ni2+ et Cd2+) migrent vers la cathode où le cadmium est sélectivement réduit. Nous avons étudié les possibilités de récupération des métaux, mais également tenté d'appréhender les phénomènes prenant place dans la cellule lors du couplage E/E. Dans un premier temps, nous avons choisi de démanteler manuellement des accumulateurs en raison de la complexité des broyats industriels. La matière active des accumulateurs Ni-Cd a été caractérisée. Sa composition moyenne est la suivante :Cd(OH)2 : 45,3 %, Cd0 : 0,02 %, Ni(OH)2 : 30,0 %, Ni0 :12,9 %, NiOOH : 0,9%, Co(OH)2 : 2,4 %. Au vu des différentes formes minéralogiques présentes, ce solide peut être considéré comme un déchet modèle pour ce traitement. Avant d'envisager le couplage E/E, la lixiviation chimique de la matière active par H2SO4 a d'abord été étudiée. La modélisation de cette opération a mis en évidence que la cinétique de dissolution de Cd(OH)2 est gouvernée par le transfert de masse des protons, la dissolution de Ni(OH)2 et Co(OH)2 étant quant à elle régie par la réaction chimique de surface. Dans ces conditions de lixiviation douce, le nickel métallique n'est pas oxydé et se retrouve dans le résidu solide avec le carbone. Nous avons pu démontrer ensuite la sélectivité de l'électrodéposition vis-à-vis du Co2+ et du Ni2+ avec un rendement faradique d'environ 99 % à une densité de courant de 350 A.m-2. L'étude cinétique de l'E/E a montré que l'électrolixiviation est l'étape limitante du procédé, phénomène qui a également été modélisé. L'E/E appliquée aux matériaux d'électrodes permet en 5 h 30 de lixivier 97 % du cadmium initialement présent. Le solide résiduel est composé à 82 % de nickel, principalement sous la forme métallique, 4 % de cadmium, 0,5 % de cobalt et 3 % de carbone. Le dépôt de cadmium est obtenu avec une pureté supérieure à 97 % et un rendement faradique de déposition supérieur à 74 % à une densité de courant de 350 A.m-2. La faisabilité du couplage E/E appliqué au traitement d'accumulateurs Ni-Cd en fin de vie a été démontrée malgré la complexité de la matrice. Les premiers essais d'application de ce traitement à des échantillons industriels (Cd(OH)2 : 36,1 %, Ni(OH)2 : 24,1 %, Ni0 : 16,6 %, NiOOH : 5,5 %, Co(OH)2 : 2,4 % et Fe :1% en masse) confirment les résultats obtenus avec les matériaux d'électrodes provenant du démantèlement manuel / This thesis focuses on the development of a protocol for selective extraction of metals from spent Ni-Cd batteries. Conventionally, hydrometallurgical processes applied to this type of solids involve several steps, the main ones being the leaching and the metal recovery by electrolysis. The method used consists in coupling Electroleaching to Electrodeposition operation (denoted E/E) within the same cell. The technique is based on the leaching of the active material of Ni-Cd batteries by protons generated at the anode: the cations (Co2+, Ni2+ and Cd2+) released by leaching migrate to the cathode where the cadmium is selectively reduced. We studied the possibility of metals recovery, but also tried to understand the phenomena occurring in the cell during the E/E experiments. Initially, it was preferred to manually dismantle batteries due to the complexity of industrial waste crushed. The active matter of Ni-Cd has been characterized. Its average composition is as follows: Cd(OH)2: 45.3%, Cd0: 0.02%, Ni(OH)2: 30.0%, Ni0: 12.9%, NiOOH: 0.9%, Co(OH)2: 2.4%. In view of these different mineralogical forms, this solid can be considered a model for the waste treatment. Before considering the E/E treatment, chemical leaching of the active matter by H2SO4 was first studied. Modelling of the tests carried out showed that the kinetics of Cd(OH)2 dissolution is governed by mass transfer of protons and the dissolution of Ni(OH)2 and Co(OH)2 by the surface chemical reaction. Under these conditions of soft leaching, metal nickel is not oxidized and is found in the solid residue, with carbon. We had to demonstrate the cadmium electrowinning selectivity, for separation from Co2+ and Ni2+ species, with a current efficiency up to 99% at a current density of 350 A.m-2. The kinetic study of the E/E showed that electroleaching is mainly governed by H+ generation at the anode. Besides, the overall process is largerly controlled by cations transport from the anode to the cathode side: this transport phenomenon had also been modeled. The E/E applied to the electrode materials for 5 h 30 allows the leaching of 97% of the cadmium initially present. The residual solid is composed by 82% of nickel, mainly in the metallic form, 4% of cadmium, 0.5% of cobalt and 3% carbon. The deposition of cadmium is obtained with a purity greater than 97% and a current efficiency greater than 74% at a current density of 350 A.m-2. The feasibility of the E/E coupling applied to the spent Ni-Cd batteries treatment has been demonstrated despite the complexity of the matrix. The first tests to apply this treatment to industrial samples (Cd(OH)2: 36.1% Ni(OH)2: 24.1% Ni0: 16.6% NiOOH: 5.5% Co(OH)2: 2.4% and Fe: 1% by weight) confirm the results obtained with the electrode material from the manual dismantling
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Aplikace vyhlášky č. 424/2004 Sb. v návaznosti na práci sestry ve zdravotnických zařízeních / Applied work by well know nurses according to 424/2004 in the medical servicesJÍLKOVÁ, Milena January 2008 (has links)
The topic of this diploma work is about the application of public notice No. 424/2004 Sb.in a matter of nurses{\crq} work duties in health service. It is based on two aims. The first aim is to find out observance of public notice No. 424/2004 Sb. in departments like (surgery,and internal medicine) in hospitals in South Bohemian region and the second aim is to find out the nurses{\crq} knowledge about their personal competences. Theoretic part talks about history, nurses education, registration and the public notice No. 424/2004 Sb. and the law No. 96/2004 Sb. Practical part contains results of the research, 25 graphs clearly shows general answered questions from questionnaire by nurses. There are commented stated records in symposium. On the basis of these results I may note that nurses from surgical department 61% (52) and nurses from internal department 58% (49) marked the correct answer what the public notice No. 424/2004 Sb. is about but they did not prove the knowledge of their personal competences sequent upon those public notices. Nurses from surgery 46% (39) and nurses from internal medicine 31% (26) are often accredit by tasks given by doctors that are not beyond their cognizance.
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Expression des Gonadotropin-Releasing-Hormon (GnRH)-Rezeptors in primären humanen Osteoblasten und Effekte des GnRH-Agonisten Triptorelin auf die Expression osteoblastärer Gene / Expression of gonadotropin-releasing hormone (GnRH) receptor in human primary osteoblasts (hOB) and direct effects of GnRH analogs on hOB gene expressionKlompen, Julia 03 March 2010 (has links)
No description available.
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Glioblastomtherapie von 1998 bis 2004 in der Universitätsklinik Göttingen / Eine retrospektive Analyse zeitgemäßer Behandlungsstrategien / Glioblastoma treatment from 1998 to 2004 in Göttingen University Hospital / A retrospective analysis of current treatment regimenEchegoyen Hornfeldt, Yvonne 08 December 2010 (has links)
No description available.
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