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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Validierung eines Computerprogramms zur Simulation des intraoperativen Temperaturverlaufs und zur Vorhersage des Auftretens von perioperativer Hypothermie / Validation of a program simulating intraoperative temperature profiles and forecasting perioperative hypothermia

Gassner, Sebastian Gerhard 10 May 2010 (has links)
No description available.
2

Stickoxidmetabolite als Ursache einer differentiellen Myelingenexpression in MS-Läsionen? / Nitric oxide metabolites: the cause of dysregulation of myelin protein genes in multiple sclerosis lesions?

Beck, Anna Katharina 03 May 2011 (has links)
No description available.
3

Epigenetische Beeinflussung der Proliferation, Expression von Matrix-Metalloproteinasen, Migration und Invasion von Harnblasenkarzinomzelllinien / Epigenetic influence on proliferation, expression of matrix-metalloproteinases, migration and invasion of bladder cancer cell lines

Kosz, Magdalena 01 June 2010 (has links)
No description available.
4

Chromosomale Veränderungen von Hirnmetastasen klarzelliger Nierenzellkarzinome / Chromosomal alterations of brain metastases of clear cell renal cell carcinomas

Nischwitz, Martin David 29 June 2010 (has links)
No description available.
5

Prädiktives und prognostisches Potential der Thymidylatsynthase als Biomarker im multimodalen Therapiekonzept 5-FU-basierter Radiochemotherapie des lokal fortgeschrittenen Rektumkarzinoms / Immunhistochemische Analyse prätherapeutischer Biopsien und korrespondierenden residuellen Tumorgewebes / Predictive and prognostic significance of thymdylate synthase as biomarker in multimodal treatment of 5-FU-based radiochemotherapy of locally advanced rectal cancer / Immunhistochemical analyses of pre-treatment biopsies and corresponding residual tumor tissue

Conradi, Lena-Christin 16 November 2010 (has links)
No description available.
6

Expression und Funktion des Vitamin-D-Rezeptors in malignen Keimzelltumoren des Hodens / Expression and function of the Vitamin D receptor in malignant germ cell tumour of the testis

Bremmer, Felix 02 March 2011 (has links)
No description available.
7

Chromosomale Veränderungen in Hirnmetastasen vom Lungenkrebs / Chromosomal aberrations in brain metastases of lung cancer

Klipp, Gerrit Christopher 26 November 2012 (has links)
No description available.
8

Grey matter pathology in multiple sclerosis

Albert, Monika 27 October 2005 (has links)
No description available.
9

Molekulargenetische Analysen zur Etablierung eines Progressionsmodells des Pankreaskarzinoms

Galehdari, Hamid 26 September 2000 (has links)
Recently the suspected precursor lesions of ductal adenocarcinoma of the pancreas have been called Pancreatic intraepithelial neoplasia (PanIN) and graded according to the degree of dysplasia. To correlate each grade of PanIN with molecular genetic alterations, we determined the frequency of allelic losses at chromosomal arms 9p (the location of the p16 gene), 17p (p53 gene) and 18q (DPC4/SMAD4 gene) in 81 microdissected PanINs, using a combination of whole genome amplification and microsatellite analysis. In addition, p53 and Dpc4 protein expression was determined by immunohistochemistry. Essentially no allelic losses were identified in the non-dysplastic PanIN-1 lesion. In PanIN-2 with low grade dysplasia the frequency of allelic losses at chromosomal region 9p, 17p and 18q was 20%, 33% and 17%, respectively, which increased to 46%, 77% and 58%, respectively, in PanIN-2 with moderate dysplasia, to 87%, 60% and 88% in PanIN-3 with high grade dysplasia, and to 100%, 91%, and 82% in the invasive carcinomas. The progressive occurrence of allelic losses at all three loci strongly supports the PanIN progression model for pancreatic carcinoma. Nuclear p53 and loss of Dpc4 protein expression was associated only with PanIN-3 and invasive carcinomas, consistent with the model that inactivation of p53 and DPC4 are late events in pancreatic carcinogenesis. Since the aberrant protein expression patterns, were preceded, however by a sharp increase in allelic losses from PanIN-2 with low grade dysplasia to PanIN-2 with moderate dysplasia it is suggested that the increasing grade of dysplasia in the PanIN lesions identify biologically relevant steps towards invasive carcinoma. The discrepancy between alleic loss frequencies and p53 and DPC4 expression also raises the possibility that additional tumor suppressor genes on chromosomes 17p and 18q promote early pancreatic carcinogenesis.
10

Differenzielle Regulation und prognostische Bedeutung von zellzyklusassoziierten Regulatoren der G1- und G2-Phase in Abhängigkeit von der anatomischen Lokalisation in Gastrointestinalen Stromatumoren (GIST) / Differential regulation and prognostic significance of cell cycle-associated regulators of the G1- and G2-phase subject to the anatomical localisation in gastrointestinal stromal tumors (GIST)

Cortis, Judith 27 September 2010 (has links)
No description available.

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