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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
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Showing 11 to 20 of 23 (0.008 seconds)| 11 |
Immunzellen in primären und metastasierten gastrointestinalen Stromatumoren (GISTs) / Immune cells in primary and metastatic gastrointestinal stromal tumors (GISTs)Gieselmann, Marieke Dorothea 10 November 2010 (has links)
No description available.
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Multiple Sklerose: Einflussfaktoren von Oligodendrozytendichte und Remyelinisierung, Östrogen und Progesteron als Protektiva? / Influencing Factors of Oligodendrocyte Density and Remyelination in Multiple Sclerosis or: Estrogen and Progesterone as Protective Agents?Goldschmidt, Thomas 28 June 2011 (has links)
No description available.
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Applikation der Comparativen Genomischen Hybridisierung (CGH) zur Vorhersage des Ansprechens von Rektumkarzinomen auf neoadjuvante Radiochemotherapie / Application of Comparative Genomic Hybridization (CGH) for response prediction of rectal adenocarcinoma to preoperative chemoradiotherapyBeckmann, Jaje 17 October 2011 (has links)
No description available.
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Interaktionen zwischen Acute Intracranial Hypertension und Acute Respiratory Distress Syndrome - Auswirkungen auf den hypoxiesensiblen Hippocampus / Interaction between Acute Intracranial Hypertension and Acute Respiratory Distress Syndrome - Impacts on Hypoxia Sensitive HippocampusSelke, Maren Verena 10 October 2011 (has links)
No description available.
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Risikofaktoren postoperativer Infektionen nach neurochirurgischen Eingriffen und die Rolle der perioperativen Antibiotikaprophylaxe / Risk factors for surgical site infections in neurosurgery and the role of perioperative antibioticsPauly, Franziska 21 May 2012 (has links)
No description available.
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Zytogenetische Charakterisierung der Glioblastomzelllinie G112 in Bezug auf tumorstammzellähnliche Eigenschaften und Strahlentherapie / Cytogenetic Characterisation Of Glioblastoma Cell Line G112 Concerning Tumor Stem Cell Like Properties And RadiotherapyRippl, Marina 07 January 2013 (has links)
No description available.
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Entwicklung und Einsatz der Immun-SERS-Mikroskopie zur Gewebe-basierten TumordiagnostikSalehi, Mohammad 09 September 2013 (has links)
Surface-enhanced Raman scattering (SERS) microscopy is a novel method of optical imaging for the localization and quantification of target molecules in cells and tissue specimens. The major advantages of SERS over fluorescence are quantification and spectral multiplexing due to the small line width of vibrational Raman bands. The position of the plasmon band of both hollow gold/silver nanoshells and silica-encapsulated gold nanoclusters can be tuned for maximum SERS enhancement upon red laser excitation, which is optimal for minimizing the disturbing autofluorescence of tissue. In this work, silica-encapsulated and non-encapsulated SERS particles were used for the localization of target proteins in prostate tissue specimens. Two different biofunctionalization methods were established for each type of SERS particles. The cross-linking method based on s-NHS/EDC chemistry was modified for covalently conjugating proteins to hollow gold/silver nanoshells and gold nanostars in order to minimize the aggregation of SERS nanoparticles during and after cross-linking. As an alternative to covalent conjugation chemistry, the noncovalent binding of antibodies to the SERS particles via an adapter protein (protein A/G) was established. The influence of several factors that determine the quality of results obtained by SERS imaging, such as the number of immuno-SERS conjugates, incubation time, antigen retrieval and blocking buffer, were investigated. Rapid SERS microscopy with 30 msec acquisition time per pixel was enabled by using silica-encapsulated gold nanoclusters for the localization of p63 proteins on prostate tissue specimens from healthy donors. Two-color SERS experiments for the parallel localization of PSA and p63 were performed with silica-encapsulated and non-encapsulated nanoshells. The quality of the results depends less on the nature of the surface chemistry of the nanoparticles (with or without silica encapsulation), but more on the blocking buffer and the antigen retrieval method. Silica-encapsulated gold nanoclusters were also used for the simultaneous quantification of three cytokines (IL1, IL8 and TNF- α) in a SERS-based sandwich immunoassay with a detection limit of ca. 0.3 pM.
Keywords: Raman, SERS microscopy, biocompatibility of nanoparticles, cross-linking, antigen unmasking methods, antigen detection, immunohistochemistry, immunoassay.
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Quantitative Proteinexpressionsanalysen in den klinisch-pathologischen Subtypen Gastrointestinaler Stromatumoren (GIST) / The analysis of the quantitative protein expression in the clinical-pathological subtypes of Gastrointestinal stromal tumors (GIST)Helfrich, Joel 02 March 2011 (has links)
No description available.
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Immunhistochemischer Algorithmus zur Diagnostik maligner Keimzelltumoren des Hodens / Immunohistochemical algorithm for the diagnosis of malignant germ cell tumors of the testisMayer-Eichberger, Katharina 28 March 2011 (has links)
No description available.
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Zytogenetische Grundlage der malignen Progression anaplastischer Astrozytome: Chromosomale Aberrationen von Primärtumoren, Rezidiven und ihr Einfluss auf das Überleben / Cytogenetic basics of malignant progression of anaplastic astrocytoma: Chromosomal aberrations of primary and recurrent tumors and their influence on survivalHaupt, Jörn 02 November 2011 (has links)
No description available.
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