This project explores the treatment of Catalan – as a minority language in the international audiovisual landscape and in the film industry – in its translation into English, the majority language of communication within the audiovisual medium, through film subtitling. For the purpose of analysis, the translation of culture-bound elements was selected as the focal point to examine the behaviour of subtitlers in response to the translation problem arising from the presence of culture-bound elements in the source texts. The corpus for this study comprises fourteen Catalan films by the director Ventura Pons, together with their English-subtitled versions. Ventura Pons is considered one of the most internationally recognised directors of Catalan cinema today and his films are regarded as a reference of the autochthonous culture as well as signifiers of cultural identity. The methodological framework follows a descriptive model based on the theoretical proposals put forward by Toury (1980, 1995). This model applies an inductive method that first analyses the target text and then contrasts it with the source text in order to identify patterns that reveal possible translation norms, as defined and categorised by Toury (1995: 54). To this end, this project investigates the translation techniques and overall strategies used in the rendering of culture-bound elements from the corpus by empirically exploring the connections among the following parameters: preliminary norms, audiovisual constraints, interculturality, film genre, domain and translation techniques. More particularly, through a quantitative and qualitative analysis of the results, the study aims to reveal symptomatic patterns of translation behaviour and to identify possible translation norms that may have been adopted when rendering the culture-bound elements under study.

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Based on a Sc.D. thesis in the Dept. of Electrical Engineering, 1965. / Bibliography: p.98-99.

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Chez les vertébrés, le battement coordonné des cils motiles présents par centaines à la surface apicale des cellules multiciliées (MCC) est requis pour propulser directionnellement les fluides biologiques à l’intérieur de certains organes (voies respiratoires, ventricules cérébraux, trompes utérines ou certaines structures embryonnaires). De nombreuses pathologies humaines sont associées à des défauts ciliaires ou à une perte des MCC (dyskinésies ciliaires, mucoviscidose, asthme,...). Dans ce contexte, mon travail de thèse a consisté à élucider les mécanismes complexes contrôlant la différenciation des MCC et donc la formation des cils motiles (multiciliogenèse). Par des approches de génomiques fonctionnelles à partir de deux modèles d’épithéliums multiciliés évolutivement éloignés (épithélium respiratoire humain et épiderme d’embryon de Xénope) nous avons identifié la famille des microARN (petits ARN non-codants régulateurs de l’expression génique) miR-449 comme majoritairement exprimée dans les MCC. Nous avons montré que miR-449 contrôle la multiciliogenèse i) en bloquant le cycle cellulaire, ii) en réprimant directement la voie de signalisation Notch et iii) en inhibant l’expression de la petite GTPase R-Ras. Enfin, nos travaux montrent que l’ensemble de ces mécanismes est conservé chez les vertébrés. En conclusion, miR-449 est un nouveau régulateur clé de la multiciliogenèse conservé au cours de l’évolution. Nos résultats pourraient ouvrir la voie à de nouvelles stratégies thérapeutiques utilisant des petits ARN régulateurs dans le traitement de certaines pathologies associées à des défauts ciliaires. / In vertebrates, the coordinated beating of hundreds of motile cilia present at the apical surface of multiciliated cells (MCC) is required for propel directionally flow of biological fluids inside some organs (airways, cerebral ventricles, fallopian tubes or some embryonic structures). Many human diseases are associated with ciliary defects or loss of MCC (ciliary dyskinesia, cystic fibrosis, asthma ...). In this context, my thesis has sought to elucidate the complex mechanisms that control the differentiation of MCC and thus the formation of motile cilia (multiciliogenesis). By functional genomic approaches from two evolutionarily distant models of multiciliated epithelia (human respiratory epithelium and epidermis of Xenopus embryo) we identified the miR-449 family of microRNAs (small non-coding RNAs regulating gene expression) as mainly expressed in MCC. Then, we showed that miR-449 controlled multiciliogenesis by i) blocking the cell cycle ii) directly suppressing the Notch pathway and iii) by inhibiting the expression of the small GTPase R-Ras. Finally, we have demonstrated that all these mechanisms were conserved in vertebrates. In conclusion, miR-449 is a new key and conserved regulator of multiciliogenesis. Our findings could pave the way for new therapeutic strategies using small regulatory RNAs in the treatment of several diseases associated with ciliary defects.

This thesis investigates the role which Roman artefacts played within rural settlements in North Britain during the Romano-British period. The possibility that Roman artefacts were used by native Britons as markers of prestige is explored through the presence or absence of Roman artefact types. The more prestigious the occupants of the rural settlements were, the more likely they were to have access to a variety of exotic trade items. The methodology employed in this study has been adapted from previous studies on pottery types and settlement remains from Scotland. This thesis examines an area that centres on Hadrian's Wall, which at various times in its history acted as the frontier for the Roman Empire, as well as being a staging post for troops and a means of controlling the local population's movement. The study region includes land up to 50 kilometres either side of Hadrian's Wall, and examines rural settlements located within one or two days travel from the Wall. The excavation reports of rural settlements were examined, and include settlement types such as homesteads, hillforts and villas. From these sites, Roman artefact types were quantified and used to generate data for analysis. The results agree with the hypothesis that social hierarchy can be detected through the comparative presence or absence of Roman artefact types. It is also apparent that the settlements on either side of Hadrian's Wall, and either side of the Pennines mountain chain, were not part of a simple, homogenous culture. This thesis begins with an outline of the geographic and environmental nature of the region (Chapter 2), and an examination of settlement and society in North Britain during the preceding Bronze and Iron Ages (Chapter 3). An essay on Romano-British society and settlement is included (Chapter 4), and is followed by a brief discussion of post- Roman Britain (Chapter 5). Following an outline of the methodology used (Chapter 6), the results of analysis are presented in detail (Chapter 7). The Discussion chapter explores how the results of analysis meet existing theories of rural settlement and society, and compares North Britain with continental data from Germany and North Gaul (Chapter 8).

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