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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
41

Schulstress unter Jugendlichen Entstehungsbedingungen, vermittelnde Prozesse und Folgen ; eine empirische Studie im Rahmen von PISA 2003

Bergmüller, Silvia January 2006 (has links)
Zugl.: Salzburg, Univ., Diss., 2006
42

Der Bullying- und Viktimisierungsfragebogen Konstruktion und Analyse von Instrumenten zur Erfassung von Bullying im Vor- und Grundschulalter

Marées, Nandoli von Unknown Date (has links) (PDF)
Bremen, Univ., Diss., 2009
43

Death of a comet : SPIREX observations of the collision of SL9 with Jupiter /

Severson, Scott A. January 2000 (has links)
Thesis (Ph. D.)--University of Chicago, Dept. of Astronomy and Astrophysics, March 2000. / Includes bibliographical references. Also available on the Internet.
44

Propuesta de un sistema de semaforización para reducir el grado de saturación en las intersecciones de Av. Angamos Este con Av. República de Panamá, Av. Tomás Marsano y Av. Aviación; a través de la metodología del Ramp Metering

Basurto Valladares, Leonardo Joaquín, Yzaguirre De La Tore, Rodrigo Raúl 06 December 2019 (has links)
Actualmente, existe un incremento vehicular en Lima Metropolitana que perjudica la eficacia de las vías de comunicación terrestres. Por tal motivo, el presente tema de investigación tiene como finalidad reducir el grado de saturación en las intersecciones urbanas de la Av. Angamos Este con Av. Aviación, Av. Tomás Marsano y Av. República de Panamá ubicadas en Lima Metropolitana a través de la metodología Ramp Metering que considera desarrollar el algoritmo ALINEA. En primera instancia, se describió la situación actual de los cruces viales previamente mencionados, a partir del reconocimiento en campo. Posteriormente, se recopilaron los tiempos de verde efectivo vehicular y el ciclo semafórico peatonal. De igual manera, se contabilizó presencialmente el flujo de automóviles durante 13 horas continuas y el número de transeúntes en las intersecciones durante el mismo periodo. Subsiguientemente, se evaluaron las condiciones de circulación existente, donde el principal objetivo es determinar el grado de saturación por medio de flujogramas que permiten una mejor visualización del estado actual. Luego de lo mencionado, se empleó la estrategia ALINEA para diseñar una propuesta de mejora a partir los tiempos de verde efectivo calculados el algoritmo mencionado. Siguiendo con el procedimiento, se evaluó el diseño con el software PTV VISSIM 9.0, un programa de micro simulación acorde con los lineamientos planteados del proyecto, con la finalidad de verificar si existe una mejora relacionada al grado de saturación. Por último, se compararon las dos situaciones previstas, calculando el parámetro indicado con el programa VISSIM. / Currently, there is an exponential growth in the number of vehicles in Metropolitan Lima that harms the efficiency of the vehicle flow on the roads and highways of this city. For this reason, the present research topic aims to reduce the degree of saturation at the urban intersections of Av. Angamos Este with Av. Aviación, Av. Tomás Marsano and Av. República de Panamá located in Metropolitan Lima through the methodology of Ramp Metering that considers developing the ALINEA algorithm. In the first instance, the current situation of the previously mentioned crosses was described based on the recognition carried out in the field. Subsequently, the effective vehicular green times and the pedestrian traffic light cycle will be collected. In the same way, the traffic flow was collected for 13 consecutive hours and the number of passers-by at the intersections during the same period. Subsequently, the existing circulation conditions were evaluated, where the main objective is to determine the degree of saturation throughout flow charts that allow a better visualization of the current state. After the aforementioned, ALINEA strategy was used to design a proposal that improves the vehicle flow of the intersections based on the effective green times calculated by the algorithm mentioned. Following the procedure, the design is evaluated with the PTV VISSIM 9.0 software, a micro simulation program in accordance with the guidelines outlined in the project, with the purpose of verifying if there is an improvement related to the degree of saturation. Finally, the two situations foreseen were compared, calculating the indicated parameter with the arithmetic process of the micro simulator VISSIM. / Tesis
45

Identification of Transmembrane and Extracellular Host Proteases that Promote Human CoV Entry and Syncytium Formation

Mulloy, Rory 16 September 2021 (has links)
Coronaviruses (CoVs) comprise a family of enveloped viruses that cause respiratory disease in humans, including CoV disease 2019 (COVID-19), caused by severe-acute respiratory syndrome CoV-2 (SARS-CoV-2). For CoV infection to occur, the CoV spike (S) protein must mediate fusion between the viral and host membranes. This entry process can also be repurposed during infection to promote cell-to-cell fusion, further contributing to viral spread. To trigger fusion, S must bind its cognate receptor and be cleaved by host proteases. Identifying cellular proteases capable of triggering CoV fusion is critical to understand CoV entry, tropism, and cell-cell spread, however the range of proteases capable of promoting CoV fusion has not been fully explored. Here, using fusion and entry assays, I provide evidence implicating matrix metalloproteinase-9 (MMP-9) as a fusion trigger for SARS-CoV-2 and HCoV-229E. Additionally, I show MMP-9 expression is upregulated during CoV infection, highlighting its potential relevance as a CoV triggering factor.
46

The Effects of Early-Life Lead Exposure on Adult Delta9-Tetrahydrocannabinol Sensitivity, Self-administration, and Tolerance

Garcy, Daniel 08 1900 (has links)
Indiana University-Purdue University Indianapolis (IUPUI) / Environmental exposure to lead (Pb) and cannabis use are two of the largest public health issues facing modern society in the United States and around the world. Exposure to Pb in early life has been unequivocally shown to have negative impacts on development, and recent research is mounting showing that it may also predispose individuals for risk of developing substance use disorders (SUD). At the same time, societal and legal attitudes towards cannabis (main psychoactive component delta-9-tetrahydrocannabinol) have been shifting, and many American states have legalized the recreational use of cannabis. It is also the 3rd most widely used drug of abuse in the US, and rates of cannabis use disorder are on the rise. This thesis sets out to establish whether there is a link between early life Pb exposure and later THC-related behavior in C57BL6/J mice, as has been demonstrated for other drugs of abuse. The first aim seeks to answer whether Pb exposure affects physiological THC sensitivity (as measured by the cannabinoid-induced tetrad). The second aim seeks to answer whether Pb exposure affects edible THC self-administration and the development of THC tolerance (also measured by the tetrad). It was hypothesized that Pb exposure would decrease THC sensitivity (Aim 1), would enhance THC self-administration (Aim 2), enhance the development of THC tolerance (Aim 2), and finally that sex-dependent effects of Pb-exposure and THC would be observed (Aims 1 & 2). These hypotheses ended up not being supported, but Aim 1 produced findings indicating that THC sensitivity was increased by Pb exposure, but only in female mice. Future research will hopefully be able to fully explore the implications of these findings.
47

Varianty chromozomu 9 u člověka - od normy k patologii Epidemiologie a význam v klinické genetické praxi. / Variants of human chromosome 9 - from norm to pathology Epidemiology and significance for medical genetics.

Šípek, Antonín January 2019 (has links)
Heterochromatin variants of human chromosome 9 belong to the most common variabilities of human karyotype. The variability involves the large block of constitutive heterochromatin in the pericentric region of chromosome 9, which is composed of various types of repetitive DNA sequences. Those variants can be studied from population epidemiologic, molecular cytogenetic and clinical genetic point of view. We have performed a broad epidemiologic study of the incidence of pericentric inversion of chromosome 9 (inv(9)) and other variants of chromosome 9 in 6 different laboratory cohorts, which included the evaluation of more than 26.000 of cytogenetic reports, the study we published is currently the largest in the world. We expressed the overall incidence of inv(9) to be 1.6% and the total incidence of variants of chromosome 9 to be 3.3-3.9%. Inv(9) was more common in females, however the difference was not statistically significant. Molecular cytogenetic part of the project was based on our own diagnostic approach, which involved the combination of three different commercial FISH probes. Combination of those probes allowed us to differentiate particular subvariants of chromosome 9, which cannot be analyzed only by using G- or C-banding. Using our method, we tested 49 carriers of chromosome 9...
48

Christ is God Over All: Romans 9:5 in the Context of Romans 9-11

Carraway, George Warrington 23 May 2012 (has links)
This dissertation examines Paul's statement in Romans 9:5 within the context of Romans 9-11. The thesis of the dissertation is that in the Christological passages in Romans 9-11, Paul spoke of Jesus in a manner that suggests that in Romans 9:5 he meant that Christ is God over all, that is, the God of Israel. In addition, the dissertation argues that the confession that Jesus is God over all is the fundamental confession that must be made by Israel for salvation. Chapter 1 considers the history of the discussion of New Testament Christology during the last century, and suggests that the question of whether any Palestinian Jew could refer to Jesus as God or even as Lord is the proper background against which the discussion of Paul's intent in Romans 9:5 must be undertaken. Chapter 2 undertakes an in-depth exegetical study of the syntax of Romans 9:5 and argues that the syntax is best understood as identifying Jesus as God. Chapter 3 acknowledges and answers objections from outside Romans 9:5 that Paul as a monotheistic Jew would not identify Jesus as God. Similarly, chapter 4 answers objections that Paul would not refer to Jesus as God in Romans 9:5 because he does not so identify Jesus elsewhere. Chapter 5 considers the importance of Paul's identification of Christ as the stone of stumbling and the end of the law in Romans 9:30-10:4, especially for how he understood Jesus. Chapter 6 argues that in Romans 10:5-13, Paul understood Jesus as the referent of the one on whom all call for salvation, assigning to Jesus an Old Testament reference to YHWH as the one who could save. Chapter 7 argues there is no separate way of salvation for Israel and that Jesus is YHWH, the redeemer from Zion, which Israel must join Gentiles in recognizing. / This item is under embargo until 2013-05-23
49

Las transformaciones de la cultura bushi en la sociedad Tokugawa

Pita Céspedes, Gustavo 08 July 2013 (has links)
Nuestra investigación tiene como propósito fundamental caracterizar la cultura bushi (武士) como un sistema integral e internamente diferenciado. Esta caracterización está basada en el estudio del proceso de su desenvolvimiento histórico, de formación e integración de sus diversos componentes, a partir de las postrimerías de la época Heian. Nos interesa mostrar a lo largo de estas etapas su interacción con otras culturas y con la sociedad como conglomerado de relaciones sociales. De especial interés resultan para nuestro estudio las transformaciones estructurales y funcionales que experimenta la cultura bushi en los marcos de la sociedad Tokugawa, así como su ulterior destino desde los grandes cambios sociales de la época Meiji hasta la actualidad. En estrecha relación con esto, un aspecto particular de nuestra investigación es el estudio del desenvolvimiento histórico de las artes marciales japonesas, así como de su funcionamiento cultural. Nuestra tesis, además de la introducción y las conclusiones, consta de cinco capítulos: en el primero se examinan los orígenes históricos de los bushi; en el segundo, el establecimiento de los antecedentes de su cultura durante la época Kamakura; en el tercero, la consolidación de la cultura bushi durante la época Muromachi; en el cuarto, el desenvolvimiento de la técnica combativa o bujutsu (武術) durante el período Sengoku (戦国), en el tránsito hacia la época Edo; y en el quinto, las metamorfosis que experimenta esa cultura, consolidada en la época Muromachi, cuando comienza a funcionar en los marcos de la sociedad Tokugawa durante una prolongada época de paz, así como en el período bakumatsu (幕末) con el arribo a Japón de las potencias extranjeras de Europa y Norteamérica. El trasfondo conceptual de la tesis es el análisis de nociones comúnmente usadas en la bibliografía como “clase guerrera”, “clase samurái”, “sociedad buke” (buke shakai [武家社会]) y “arte marcial”. Colateralmente, a lo largo de la tesis se efectúa un estudio histórico-morfológico de las artes marciales japonesas y de las principales regularidades de su desenvolvimiento. Se han empleado básicamente materiales escritos en japonés, tanto por autores contemporáneos como antiguos. Entre estos, los códigos de los clanes buke (武家家訓), dos de los cuales aparecen examinados y traducidos como parte del tercer capítulo. En la medida en que el enfoque culturológico, como complemento del sociológico, busca estudiar el papel de los individuos en la historia en su esfuerzo por tratar de controlar conscientemente los procesos sociales, a lo largo de la tesis se efectúa el estudio de varias personalidades representativas, tanto del mundo del bushi en general, como de las artes marciales japonesas en particular, y se analiza el surgimiento y desenvolvimiento del sistema educativo del samurái. / Our research aims to characterize bushi (武士) culture as an integrated and internally differentiated system. This characterization is based on the study of the process of its historical development, formation and integration of its various components, from the end of the Heian period. We want to show along these stages its interaction with other cultures and society as a conglomeration of social relations. Of particular interest for our study are structural and functional changes experienced by the bushi culture within the framework of Tokugawa society and its further destination from the great social changes of the Meiji era to the present. Closely related to this, one particular aspect of our research is the study of the historical development of Japanese martial arts, and their cultural performance. Our doctoral thesis, besides the introduction and conclusions, consists of five chapters: the first examines the historical origins of the bushi warriors; the second, the establishment of the historical precedents of their culture during the Kamakura period; the third, the consolidation of bushi culture during the Muromachi period; the fourth, the development of combative technique or bujutsu (武術) during the Sengoku period (戦 国), in transit to the Edo period; and the fifth, the metamorphosis, experienced by that culture, consolidated in the Muromachi period, when it starts functioning in the frames of Tokugawa society, during a long period of peace, as well as in the bakumatsu (幕末) period with the arrival in Japan of the representatives from powerful countries of Europe and North America. The conceptual background of our doctoral thesis is the analysis of notions commonly used in the academic literature such as “warrior class”, “samurai class”, “buke society” (buke shakai [武家社会]) and “martial art”. Collaterally, throughout our thesis we make a historical-morphological study of Japanese martial arts and the main regularities of its development. Materials have been used primarily written in Japanese by both contemporary and ancient authors, among these, some codes of buke clans (武家家訓), two of which are examined and translated as part of the third chapter. To the extent that culturological approach, as a complement of the sociological one, aims to study the role of individuals in history when consciously trying to manage social processes, throughout our thesis we study several representative personalities of both bushi world in general and Japanese martial arts as well, and, in relation to this, we analyze the emergence and development of the educational system of the samurai.
50

El canal de Aragón y Cataluña: gestación, construcción y puesta en explotación (1782-1940)

Mateu González, Josep Joan 16 December 2015 (has links)
Aquesta investigació es centra en reconstruir la història del Canal d’Aragó i Catalunya, inicialment denominat Canal de Tamarit de Llitera, des dels seus primers projectes fins la seva construcció i posada en funcionament a partir de fonts molt diverses (memòries i projectes tècnics, disposicions legislatives, fulletons propagandístics, informes jurídics, articles periodístics, etc.). Els resultats indiquen que en els seus inicis sols buscava garantir les collites de la comarca de la Llitera, després fracassaren diverses iniciatives privades que esperaven obtenir grans beneficis abastint de cereals al mercat barceloní i, en darrer lloc, jugà un paper clau en la creixent implicació de l’Estat espanyol en el procés de modernització agrària mitjançant la política de foment als regs. L’arribada de l’aigua no fou la panacea que va resoldre la “qüestió agrària” que molts esperaven. No obstant, permeté un sensible increment de la producció agrícola i potencià una creixent articulació econòmica i espacial de la zona regable. / Esta investigación se centra en reconstruir la historia del Canal de Aragón y Cataluña, inicialmente llamado Canal de Tamarite de Litera, desde sus primeros proyectos hasta su construcción y puesta en funcionamiento a partir de fuentes muy diversas (memorias y proyectos técnicos, disposiciones legislativas, folletos propagandísticos, informes jurídicos, artículos periodísticos, etc.). Los resultados indican que en sus inicios solo buscaba garantizar las cosechas de la comarca de la Litera, después fracasaron diversas iniciativas privadas que esperaban obtener grandes beneficios abasteciendo de cereales el mercado barcelonés y, por último, jugó un papel clave en la creciente implicación del Estado español en el proceso de modernización agraria a través de la política de fomento a la irrigación. La llegada del agua no fue la panacea para resolver la “cuestión agraria” que muchos esperaban. Sin embargo, permitió un sensible incremento de la producción agrícola y potenció una progresiva articulación económica y espacial de la zona regable. / This research focuses on reconstructing the history of the Canal of Aragon and Catalonia, initially called Tamarite de Litera Canal, in the years between the first projects, the construction and the start up. A wide range of documentary sources has been used: technical memories and projects, legislative orders, advertising leaflets, legal pleas, newspaper articles, etc. The evidence points out that initially its mere use was only to ensure the crops of the Litera area. Later, some private enterprises which wanted to obtain big benefits by means of providing Barcelona market with cereals failed, and finally it had a key role in the growing involvement of the Spanish Government in the agricultural modernization process through foster the irrigation policy. The results demonstrate that the water arrival was not the expected panacea to solve the "agrarian question". Nevertheless, the Canal allowed a noticeable increase of the agricultural production and it enhanced progressive economic and spatial articulation of the irrigated area.

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