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No / Modern reproductive technologies are enabling the treatment of infertile men with severe disturbances of spermatogenesis. The possibility of elevated frequencies of genetically and chromosomally defective sperm has become an issue of concern with the increased usage of ICSI, which can enable men with severely impaired sperm production to father children. Several papers have been published reporting aneuploidy in oligozoospermic patients, but relatively little is known about chromosome structural aberrations in the sperm of these patients. METHODS: We examined sperm from infertile, oligozoospermic individuals for structural and numerical chromosomal abnormalities using a multicolour ACM fluorescence in situ hybridization (FISH) assay that utilizes DNA probes specific for three regions of chromosome 1 to detect human sperm that carry numerical chromosomal abnormalities plus two categories of structural aberrations: duplications and deletions of 1pter and 1cen, and chromosomal breaks within the 1cen¿1q12 region. RESULTS: There was a significant increase in the average frequencies of sperm with duplications and deletions in the infertility patients compared with the healthy concurrent controls. There was also a significantly elevated level of breaks within the 1cen¿1q12 region. There was no evidence for an increase in chromosome 1 disomy, or in diploidy. CONCLUSIONS: Our data reveal that oligozoospermia is associated with chromosomal structural abnormalities, suggesting that oligozoospermic men carry a higher burden of transmissible, chromosome damage. The findings raise the possibility of elevated levels of transmissible chromosomal defects following ICSI treatment.

Dielectric waveguides are important passive devices in optical communication systems. Circular-core fibers with slight ellipticity may lead to polarization-mode dispersion. A clear understanding of the propagation characteristics of the elliptical fibers thus becomes important for theoretical as well as practical purposes. Although mesh-dependent methods such as the finite-element method or finite-difference method, can be used to study such a complex structure, its computational task is very high. Strictly speaking, mesh-based solution does satisfy the Helmholtz equation and the solution only provided four to five significant digits. On the other hand, the highly accurate solution based on solving the Helmholtz equation of the elliptical coordinate system spend most its computational resources on computing the functional value and the zeros of the modified Mathieu functions of the first kind. Our method is based on linear combination of the exact mode-field solutions of the dielectric optical fiber. We apply the analytical continuity principle to obtain the simultaneous equation of the expansion coefficient vector. Since each basis solution satisfies the Helmholtz equation exactly, the overall solutions are very accurate and provide more than six significant digits for fibers with small elliptical eccentricity. In addition, only the Bessel functions are needed in our computation. Using cylindrical coordinate and symmetry, together with ACM principle, we simplify the problem of modal analysis of dielectric elliptical waveguides. This method also can be applied to some regular polygonal dielectric waveguides such as the large area VCESL.

<p>Doktorska disertacija se bavi istraživanjima koja imaju za cilj da unaprede<br />obrazovanje nastavničkog kadra iz oblasti informatike. Predmet istraživanja disertacije je<br />razvoj platforme koja će olak&scaron;ati sinhronizaciju razvoja nastavničkog kurikuluma iz<br />informatičke oblasti sa aktuelnim srednjo&scaron;kolskim informatičkim standardima i<br />savremenim kurikulumima za nastavnike informatike. Prvi pravac istraživanja je<br />identifikovanje stanja u oblasti obrazovanja nastavnika informatike (modaliteti<br />obrazovanja nastavnika i kompetencije koje se tim modalitetima stiču). U disertaciji se<br />stanje identifikuje na osnovu analize savremene literature, aktuelnih standarda,<br />reprezentativnih kurikuluma i preliminarnog istraživanja nad populacijom sada&scaron;njih<br />nastavnika informatike na teritoriji Vojvodine. Drugi pravac istraživanja je<br />obezbeđivanje (tehničke) pretpostavke za objektivnije i efikasnije kreiranje,<br />upoređivanje i razmenu kurikuluma. Taj pravac se odnosi na razvoj ma&scaron;inski čitljive<br />ontologije kurikuluma bazirane na većpostojećim standardima u domenu obrazovanja i<br />softverske podr&scaron;ke za upoređivanje takvih reprezentacija kurikuluma bazirane na<br />tehnologijama Semantičkog Weba.<br />Ciljevi istraživanja u disertaciji su specifikacija ma&scaron;inski čitljivog modela informatičkog<br />kurikuluma za obrazovanje nastavnika informatike, ma&scaron;inski&nbsp; čitljivog modela<br />informatičkog kurikuluma za srednjo&scaron;kolski nivo obrazovanja i razvoj prototipa<br />softverske aplikacije za verifikaciju predloženih modela.</p> / <p>The doctoral thesis deals with researches that aim to improve the education of&nbsp;teaching staff in the field of informatics. The subject of the dissertation research is to&nbsp;develop a platform that will facilitate the synchronization of the development of teaching&nbsp; curricula in the informatics field with the current secondary informatics standards and modern curricula for informatics teachers of informatics. The first research direction is to identify the state in the informatics teacher education (modalities of teacher education and competences acquired through these modalities). In the dissertation, the state is identified from the review of literature, currentstandards, representative curricula and a preliminary research on population of current informatics teachers in Vojvodina. Another research direction is to provide (technical) prerequisites for more objective and more efficient creation, comparison and exchange of curricula. That direction is related to the development of a machine-readable ontological representation of a curriculum based on existing standards in the field of education and to developing software support for comparing such representations of curricula based on the Semantic Web technologies.<br />The goals of the research in the dissertation are to specify a machine readable model of the informatics teacher education curriculum, a machine-readable model of the informatics curriculum for secondary level education and the development of a software application prototype in order to verify the proposed models.</p>

L'objectif principal de cette étude est de déterminer comment les individus impliqués dans le processus de vue comptable, regardent le rôle de l'information comptable dans un environnement économique où les marchés financiers sont dominants. L'étude tente également de déterminer si International Financial Reporting Standards (IFRS) parti dans l'accomplissement de ce rôle. À cette fin, on compare les perceptions des directeurs financiers, les analystes financiers et les auditeurs de deux environnements de marché très différents, l'Europe comme une variable pour un environnement de marché de capitaux très développés et le Brésil comme une variable pour un environnement de marché des capitaux moins développé. Par le biais d'une enquête, nous voulons déterminer si les producteurs de données comptables (directeurs financiers), les utilisateurs de ces données (analystes financiers) et les contrôleurs de l'information comptable (auditeurs) partagent les mêmes vues sur l'utilité et les objectifs du processus de la comptabilité financière. L'extension de l'étude à plusieurs pays est un des moyens possibles pour déterminer si et comment l'environnement économique affecte l'opinion des personnes interrogées sur des informations comptables. Notre instrument d'enquête a été validé en trois langues (anglais, français et portugais) et utilisé dans six groupes de pays (un pour le Brésil, quatre groupes différents pour les pays européens et un pour les autres participants volontaires). Nous avons utilisé des statistiques descriptives et l'analyse des correspondances multivariée (ACM) pour faire notre analyse et interprétation des résultats. Nos résultats suggèrent que l'activité de nos répondants ont moins d'impact sur leurs réponses que les pays ou ils sont placés. / The main objective of this study is to determine how individuals involved in the accounting process view the role of accounting information in an economic environment where capital markets are dominant. The study also attempts to determine whether International Financial Reporting Standards (IFRS) play a part in fulfilling this role. To this end, we compare the perceptions of financial officers, financial analysts and auditors from two distinctly different market environments, using Europe as a proxy for a highly developed capital market environment and Brazil as a proxy for a less developed capital market environment. By means of a survey, we want to identify whether producers of accounting data (financial officers), users of that data (financial analysts), and controllers of accounting information (auditors) share the same views on the usefulness and goals of the financial accounting process. Extending the study to several countries is a potential means for determining whether and how the economic environment affects the respondents' views of accounting information. Our survey instrument was validated in three languages (English, French and Portuguese) and applied in six groups of countries (one for Brazil, four distinct groups for European countries and one for other voluntary participants). We used descriptive statistics and multivariate correspondence analysis (MCA) to analyze and interpret the results. Our results suggest that the activity of our respondents has less influence on their answers than the country they work in.

Software development is notorious for failure, typically defined as over budget, late delivery and/or poor quality of new information systems (IS) on project completion. The consequences of such failure can be enormous, particularly financially. As such, there is consensus by practitioners and academics alike that this practice is unacceptable. Yet with a variety of accepted development methods and tools available for use by software developers and project managers, there is still no significant reduction in the size or frequency of failure reported. In an attempt to understand the conflicts which arise in the development environment in which developers and project managers must operate, the research area is the role and value of ethics in the development of managed software projects. A definition of ethics in this context was provided by the IEEE/ACM Code of Ethics. Research was additionally conducted to understand how other professions and business areas define and enforce ethics in their respective working environments. These were (UK) Law, Finance, Retail and, law practice in the European Union. Interpretive research was then conducted to enable software development practices to be understood from the view of developers and project managers in industry. Unethical practices were then identified in a large IT company based in west London via a single, six month in-depth case study, with the data collected analysed via a series of repertory grids. Analysis and triangulation of the data collected via interviews, document analysis and observations led to an improved understanding of the causes of the unethical practices found. Conclusions and recommendations are then provided relating to implications for (a) the company participating in the research, (b) the application of the IEEE/ACM Code in industry (c) theory for ethicists.

BARROS, Francisco Ferreira do Rego. Análise da pobreza unidimensional e multidimensional no Nordeste do Brasil em 2009 e 2012. 2014. 37f. Dissertação (Mestrado Profissional) - Programa de Pós Graduação em Economia, CAEN, Universidade Federal do Ceará, Fortaleza-CE, 2014. / Submitted by Mônica Correia Aquino (monicacorreiaaquino@gmail.com) on 2014-10-30T12:36:29Z No. of bitstreams: 1 2014_dissert_ffrbarros.pdf: 532253 bytes, checksum: 9f2a7cbac33572c37156c4af34e567c3 (MD5) / Approved for entry into archive by Mônica Correia Aquino(monicacorreiaaquino@gmail.com) on 2014-10-30T12:36:46Z (GMT) No. of bitstreams: 1 2014_dissert_ffrbarros.pdf: 532253 bytes, checksum: 9f2a7cbac33572c37156c4af34e567c3 (MD5) / Made available in DSpace on 2014-10-30T12:36:46Z (GMT). No. of bitstreams: 1 2014_dissert_ffrbarros.pdf: 532253 bytes, checksum: 9f2a7cbac33572c37156c4af34e567c3 (MD5) Previous issue date: 2014 / This dissertation aims to analyze poverty on the one-dimensional and multidimensional aspect in the Northeast, from the approach to Multivariate Poverty Index ( IMP ) proposed by Asselin (2002 ) . Specifically , we use the multivariate technique of Multiple Correspondence Analysis ( MCA) , which estimates the IMP . Based on this indicator it is possible to find the ratio of the Poor - FGT ( 0 ) , intensity Poor - FGT ( 1 ) and Severity of Poverty - FGT ( 2 ) . Information PNADs were used in 2009 and 2012 . The results showed that the proportion of measured poverty , using multidimensional analysis for the region and the northeastern states in 2009 and 2012 is higher than the results obtained by dimensional analysis , using the same data , but based it is only in equities , as commonly underlie the criteria of one-dimensional technique. Thus , it became evident to be more objective use of the multidimensional method for the analysis of the problem , which , based on a larger common to the object number of variables analyzed , showed strongest results for the definition of the real level of poverty in that population. / A presente Dissertação tem como objetivo analisar a pobreza sobre o aspecto unidimensional e Multidimensional no Nordeste, a partir da abordagem do Índice Multivariado de Pobreza (IMP) proposto por Asselin (2002). Especificamente, utiliza-se a técnica multivariada de Análise de Correspondência Múltipla (ACM), que permite calcular o IMP. Com base nesse indicador é possível encontrar a proporção de Pobres - FGT(0), Intensidade de Pobres - FGT(1) e Severidade da Pobreza - FGT(2). Foram utilizadas informações das PNADs em 2009 e 2012. Os resultados permitiram concluir que a proporção de pobreza mensurada, empregando-se a análise multidimensional para a região e os estados nordestinos, em 2009 e 2012, é superior aos resultados obtidos através da análise unidimensional, utilizando-se os mesmos dados, mas, baseando-se, apenas, na variável renda, conforme comumente, fundamentam-se os critérios da técnica unidimensional. Desse modo, ficou evidenciado ser mais objetiva a utilização do método multidimensional, para a análise do problema, o qual, fundamentado em um número maior de variáveis comuns ao objeto analisado, apresentou resultados mais contundentes para a definição do nível real de pobreza naquela população.

Dissertação (mestrado)—Universidade de Brasília, Faculdade de Tecnologia, Departamento de Engenharia Civil e Ambiental, 2012. / Submitted by Albânia Cézar de Melo (albania@bce.unb.br) on 2013-01-30T12:09:33Z No. of bitstreams: 1 2012_GrazielaMorenoMonteiroMartinsGouvea.pdf: 3653104 bytes, checksum: a9963bcacf6fdbac2590a343e672990b (MD5) / Approved for entry into archive by Guimaraes Jacqueline(jacqueline.guimaraes@bce.unb.br) on 2013-01-31T10:52:00Z (GMT) No. of bitstreams: 1 2012_GrazielaMorenoMonteiroMartinsGouvea.pdf: 3653104 bytes, checksum: a9963bcacf6fdbac2590a343e672990b (MD5) / Made available in DSpace on 2013-01-31T10:52:00Z (GMT). No. of bitstreams: 1 2012_GrazielaMorenoMonteiroMartinsGouvea.pdf: 3653104 bytes, checksum: a9963bcacf6fdbac2590a343e672990b (MD5) / Nas últimas décadas, a importância dada à imagem transmitida pelos edifícios por meio de suas fachadas levou ao aumento da utilização de panos de vidro associados a revestimentos de alta tecnologia, sendo o ACM (Aluminum composite material) um dos materiais mais utilizados nas fachadas “high-tech”. Devido a fatores como rapidez na execução e possibilidade de instalação sobre outros revestimentos sem necessidade de demolição, o ACM também tem sido muito utilizado em reformas de fachadas. No entanto, 63,31% da massa dos materiais componentes das fachadas com ACM é composta por alumínio, um material cuja produção demanda altas taxas de consumo de energia e emite grande quantidade de CO₂. Dessa forma, sob o ponto de vista energético-ambiental, a reciclagem se apresenta como um importante recurso na busca da sustentabilidade desse tipo de fachada. Por outro lado, existem entraves ao reaproveitamento dos resíduos gerados na etapa de montagem e instalação, como por exemplo, o fato do ACM ser um compósito que necessita ser delaminado para que seus componentes tenham valor comercial. Sendo assim, com o objetivo de contribuir para os estudos sobre o desempenho ambiental de fachadas, este trabalho apresenta a avaliação energético-ambiental da fachada com ACM considerando-se a reciclagem, ou seja, foram comparados os valores levantados de energia incorporada e emissões de CO₂ para a fabricação de uma unidade de fachada com ACM utilizando-se matéria-prima primária e secundária, a fim de avaliar a efetiva contribuição da reciclagem na diminuição desses valores. Também foi desenhado o fluxo dos resíduos sólidos e dos agentes participantes no processo de reciclagem desses resíduos, gerados nas etapas de usinagem dos painéis de ACM e instalação das fachadas, a fim de apresentar os principais gargalos para sua reinserção no ciclo de produção dos materiais, considerando-se o contexto de Brasília. Como resultados, observou-se que a fachada produzida com matéria prima secundária pode representar uma economia de energia de 78 % e emitir 73% menos CO2. ______________________________________________________________________________ ABSTRACT / In recent decades, the importance given to the image sent out by the buildings through their facades has induced to improve the use of glass walls associated with high-tech coatings, and the ACM (Aluminum Composite Material) one of the most used materials on the facades "high- tech". As a consequence of factors such as fasten execution and the possibility of installation over other building coatings without the need for demolition, the ACM also has been used in facade`s reformation. However, 63.31% of the weights of the materials that compose the facade with ACM are made by aluminum, a material whose production demand high levels of consumption of energy and emits a huge amount of CO2. Therefore, based on the viewpoint of energy-environment, recycling represents an important resource in the quest for sustainability in this type of facade. On the other hand, there are obstacles in the waste recycling, such as the fact that the ACM is a composite which need to be delaminated for its components have a commercial value. As a result, in order to contribute for the studies on the environmental performance of facades, this paper presents the energy-environmental assessment of the facade with ACM considering recycling, for that reason, it was compared the values obtained of embodied energy and emissions CO₂ for the manufacture of a facade unit with ACM using primary and secondary raw material, with a purpose to evaluate the effective contribution of recycling in the decrease of these values. Also it was designed a flow of solid waste and of the agents that are involved in the recycling process of waste produced in the machining step of ACM panels and installation of facades, in order to demonstrate the main difficulties for the reintegration of these wastes in the production cycle of materials, considering the Brasilia`s context. The results showed that the facade with secondary raw materials produced may represent an energy saving of 78% and 73% less CO2 issue.

Submitted by admin tede (tede@pucgoias.edu.br) on 2018-12-17T18:36:39Z No. of bitstreams: 1 Daniela Sousa Guedes Meireles Rocha.pdf: 7525991 bytes, checksum: e5bf7e6cbbea752acfd4642380eda298 (MD5) / Made available in DSpace on 2018-12-17T18:36:39Z (GMT). No. of bitstreams: 1 Daniela Sousa Guedes Meireles Rocha.pdf: 7525991 bytes, checksum: e5bf7e6cbbea752acfd4642380eda298 (MD5) Previous issue date: 2018-09-27 / Introduction: Civil construction uses a significant quantity of materials and consequently, if poorly managed, can culminate in tons of undue disposal. In this way, engineers become (co) responsible for bringing environmental sustainability into the daily life of their works, with optimization of materials, waste reduction and efficient and humanized manpower management. In order to do so, Higher Education Institutions (HEIs) can exert influence in the training of these professionals, being an agent that contributes to the transformation of the posture of the future engineer, and may arouse students' interest in sustainability related topics. Objectives: To evaluate the perception and commitment of Civil Engineering students from the Pontifical Catholic University of Goiás (PUC / GO) based on the principles that guide sustainability, and to identify in the Curricular Matrices of Brazilian HEIs the quantitative of disciplines involving sustainability education and propose a possible change in the Curricular Matrix of PUC/GO. Methods: Descriptive, exploratory study of a quantitative-qualitative nature, whose research source was the application of the Survey questionnaire, using the Multiple Correspondence Analysis technique for analysis and statistical inferences. Results: Civil Engineering students from PUC/GO are mostly males (54%), aged 22 to 25 (57%) and have income between one and two minimum wages (37%). The research demonstrated that the students have knowledge by the subject "sustainability" and had access in the IES to contents that approach the sustainable development. However, not all future professionals are interested in developing skills based on sustainable guidelines. From the analysis of the curricular matrices of 163 Civil Engineering courses, it was verified that only (5.9%) of the subjects deal with sustainability, thus presenting the need for changes in the curricular matrix and in the syllabuses in the subjects, the which were suggested in this work. Conclusions: This research comprised that the student of Civil Engineering is said to possess little knowledge to act in accordance with the Sustainable Development (SD), and most appropriated the theme during the course of all their training as an individual and not necessarily during the course of graduation. The information obtained in this dissertation, associated with other research already done on the subject, proposes to the HEIs a review of their curricular matrices and contents, providing more suitable conditions for the learning of these future professionals, in relation to the issues of Sustainable Development. / Introdução: A construção civil utiliza um expressivo quantitativo de materiais e consequentemente, se mal geridos, podem culminar em toneladas de descarte indevido. Deste modo, os engenheiros tornam-se (co)responsáveis por trazerem a sustentabilidade ambiental no cotidiano de suas obras, com otimização de materiais, redução de desperdícios e um gerenciamento da mão-de-obra eficiente e humanizado. Para tanto, as Instituições de Ensino Superior (IES) podem exercer influência na formação desses profissionais, sendo agente que contribui na transformação na postura do futuro engenheiro, podendo despertar o interesse dos discentes nos temas relacionados à sustentabilidade. Objetivos: Avaliar a percepção e o comprometimento dos alunos de Engenharia Civil da Pontifícia Universidade Católica de Goiás (PUC/GO) a partir dos princípios que norteiam a sustentabilidade, além disso, identificar nas Matrizes Curriculares de IES brasileiras o quantitativo de disciplinas que envolvem a educação voltada à sustentabilidade e propor uma possível mudança na Matriz Curricular da PUC/GO. Métodos: Estudo descritivo, exploratório de natureza quanti-qualitativa, que teve como fonte de investigação a aplicação do questionário Survey, com o uso da técnica de Análise de Correspondência Múltipla para análise e inferências estatísticas. Resultados: Os discentes de Engenharia Civil da PUC/GO são em sua maioria do sexo masculino (54%,) com idade entre 22 a 25 anos (57%) e possui renda entre um e dois salários mínimos (37%). A pesquisa demonstrou que os discentes possuem conhecimento pelo tema “sustentabilidade” e tiveram acesso nas IES a conteúdos que abordam o desenvolvimento sustentável. Porém, nem todos os futuros profissionais estão interessados em desenvolver habilidades pautadas nas diretrizes sustentáveis. A partir da análise das matrizes curriculares de 163 cursos de Engenharia Civil, verificouse que apenas (5,9%) das disciplinas, versam sobre a sustentabilidade, apresentando assim, a necessidade de mudanças da matriz curricular e das ementas nas disciplinas, as quais foram sugeridas neste trabalho. Conclusões: Esta pesquisa compreendeu que o estudante de Engenharia Civil se diz possuir pouco conhecimento para atuar em conformidade com o Desenvolvimento Sustentável (DS), e a maioria apropriou-se do tema no decorrer de toda sua formação como indivíduo e não necessariamente durante o curso de graduação. As informações obtidas nesta dissertação, associadas a outras pesquisas já realizadas sobre o tema, propõe às IES revisão de suas matrizes curriculares e conteúdos, proporcionando condições mais adequadas à aprendizagem destes futuros profissionais, em relação às questões do Desenvolvimento Sustentável.

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