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Comparison of Washington state 2010 Medicare prescription drug plan coverage of pharmacotherapies for opioid and alcohol dependenceDipzinski, Aaron. January 2010 (has links) (PDF)
Thesis (M.H.P.A.)--Washington State University, May 2010. / Title from PDF title page (viewed on July 22, 2010). "Department of Health Policy and Administration." Includes bibliographical references (p. 42-51).
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Personality processes in the development of alcohol problems during the college years and beyond /O'Neill, Susan E., January 2004 (has links)
Thesis (Ph.D.)--University of Missouri-Columbia, 2004. / Typescript. Vita. Includes bibliographical references (leaves 59-72). Also available on the Internet.
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Illinois Department of Alcoholism and Substance Abuse counselor training programs an impact study /Lott, Sandra Brodersen-Schneider Hinrichs. Baker, Paul J. January 1989 (has links)
Thesis (Ph. D.)--Illinois State University, 1989. / Title from title page screen, viewed October 25, 2005. Dissertation Committee: Paul J. Baker (chair), Jack C. Eisele, George Padavil, Alan R. Sodetz, Calvin L. Stockman. Includes bibliographical references (leaves 177-182) and abstract. Also available in print.
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Religiosity, physical disability, and the social distribution of problematic drinking in an aging populationEliassen, A. Henry. Turner, R. Jay. January 1900 (has links)
Thesis (Ph. D.)--Florida State University, 2006. / Advisor: R. Jay Turner, Florida State University, College of Social Sciences, Dept. of Sociology. Title and description from dissertation home page (viewed Sept. 19, 2006). Document formatted into pages; contains xiii, 140 pages. Includes bibliographical references.
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Personality processes in the development of alcohol problems during the college years and beyondO'Neill, Susan E., January 2004 (has links)
Thesis (Ph.D.)--University of Missouri-Columbia, 2004. / Typescript. Vita. Includes bibliographical references (leaves 59-72). Also available on the Internet.
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Consumo de bebidas alcoólicas e risco nutricional em universitários do campus da Unesp - Araraquara-SPFonseca, Taís Turrioni [UNESP] 23 November 2006 (has links) (PDF)
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fonseca_tt_me_arafcf.pdf: 793353 bytes, checksum: fc392aa0437b46104fc8d76978bf98b7 (MD5) / Universidade Estadual Paulista (UNESP) / Em algumas culturas a bebida alcoólica é um alimento, utilizado durante as refeições, consumida moderadamente. Porém, quando utilizada fora deste contexto, como é o caso do Brasil e da maioria das culturas ocidentais, apresenta-se como o veículo da droga álcool etílico ou etanol. O uso de substâncias lícitas e ilícitas tem sido avaliado entre estudantes das universidades estaduais paulistas e já se constatou que as drogas lícitas, álcool e tabaco, são as mais consumidas e estão freqüentemente presentes como fatores de risco para o consumo de drogas ilícitas. Esta pesquisa objetivou avaliar o consumo de bebidas alcoólicas e o risco à saúde de alunos da Universidade Estadual Paulista Júlio de Mesquita, campus de Araraquara, São Paulo, Brasil. A amostra esteve composta por 872 alunos, que responderam a um questionário anonimamente. Os dados foram analisados por meio da distribuição de freqüências e associações estudadas por meio do teste do qui-quadrado com nível de significância de 5%. A avaliação do questionário mostrou que o consumo de bebidas alcoólicas é crescente do 1o aos últimos anos e que há uma mudança expressiva no perfil de consumo feminino com a proximidade dos últimos anos, indicadores que apontam para a necessidade de implementação de ações preventivas anteriores ao ingresso no ensino universitário, principalmente entre estudantes do sexo feminino. / In some cultures the alcoholic beverage are like a food, used at meals, moderately consumed. However, when used outside of this context, as it is the case of Brazil and the majority of the occidental cultures, it is presented as the vehicle of the alcohol etilico or ethanol drug. The allowed and illicit substance use has been evaluated between students of the São Paulo state universities and already it was evidenced that the allowed drugs, alcohol and tobacco, are consumed and are frequently gifts as factors of risk for the consumption of illicit drugs. This research objectified to evaluate the consumption of alcoholic beverages and the risk to the health among students from Universidade Estadual Paulista Júlio de Mesquita, campus of Araraquara, São Paulo, Brazil. The sample was composed for 872 students, who had answered anonimamente to a questionnarie. The data had been analyzed by means of the distribution of frequencies and associations studied by means of the test of the qui-square with level of significance of 5%. The evaluation of the questionnarie showed that the alcoholic beverage consumption is increasing of 1º to the last years and that has a considerable change in the profile of female consumption with the proximity of the last years, pointers that point with respect to the necessity of implementation of previous injunctions to the ingression in university education, mainly between students of the female sex.
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Consumo de álcool entre estudantes do ensino médio do município de Passos-MGAlmeida, Jussara de Castro [UNESP] 13 July 2009 (has links) (PDF)
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almeida_jc_me_arafcf.pdf: 403781 bytes, checksum: cb11387cdb57181647da436b205e960f (MD5) / Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) / O objetivo deste estudo foi identificar o padrão de consumo de álcool entre estudantes do ensino médio do município de Passos-MG e sua associação com fatores sócio-demográficos. Para tanto, apresenta-se três capítulos. No capítulo 1 realizou-se uma revisão de literatura para identificar a magnitude, os fatores de risco e de proteção e as consequências do consumo de bebidas alcoólicas na adolescência. No segundo capítulo, estimou-se a confiabilidade do Teste de Identificação de Desordens Devido ao Álcool (AUDIT) em 62 estudantes do ensino médio do município de Passos – MG e verificou-se excelente consistência interna ( =0,77) e reprodutibilidade ( =0,92). O capítulo 3 foi realizado com o objetivo de identificar o padrão de consumo de álcool entre estudantes do ensino médio de Passos – MG e sua associação com fatores sóciodemográficos. Para tanto, adotou-se delineamento amostral probabilístico estratificado segundo o tipo de instituição de ensino (pública e privada), número de estudantes por escola, série cursada e sexo. Participaram do estudo 1.967 adolescentes. Para identificação de desordens devido ao álcool utilizou-se o questionário AUDIT. Realizou-se estatística descritiva, o teste de qui-quadrado e regressão logística múltipla. O nível de significância adotado foi de 5,00%. A média de idade dos participantes foi de 15,84±1,23 anos e 57,38% eram do sexo feminino. O primeiro contato com o álcool ocorreu aos 13,37±1,92 anos. Dos adolescentes, 30,96% eram abstêmios, 45,76% apresentaram comportamento de beber moderado, 16,47% beber de risco, 3,51% beber de alto risco e 3,31% possível dependência. Houve associação significativa entre o risco de beber e o sexo ( 2=9,640, p=0,002), relacionamento do adolescente com a mãe ( 2=14,603, p=0,001), trabalho ( 2=8,754, p=0,003), nível econômico ( 2=4,074, p=0,044) e escolaridade do chefe... / The aim of this study was to identify the pattern of alcohol consumption among high school students in the municipality of Passos-MG, and its association with socialdemographic factors. For both, has three chapters. In Chapter 1 there was a literature review to identify the magnitude, risk factors and protection and the consequences of alcohol consumption in adolescence. The second chapter aims to estimate the reliability of the Alcohol Use Disorder Identification Test (AUDIT) in 62 high school students in the municipality of Passos - MG and there was excellent internal consistency ( =0.77) and reproducibility ( =0.92). Chapter 3 was carried out to identify the pattern of alcohol consumption among high school students from Passos-MG and its association with social-demographic factors. Thus, adopted probabilistic sampling design was stratified by type of education institution (public and private), number of students per school, set course and sex. Study participants were 1,967 adolescents. For identification of disorders due to alcohol using the AUDIT questionnaire. There was descriptive statistics, the chi-square test and multiple logistic regression. The significance level was 5.00%. The average age of participants was 15.84±1.23 years and 57.38% were female. The first contact with alcohol occurred at 13.37±1.92 years. Of adolescents, 30.96% were abstainers, 45.76% had moderate drinking behavior, drinking risk 16.47%, 3.51% high-risk drinking and 3.31% possible dependency. There was a significant association between the risk of drinking and sex ( 2=9.640, p=0.002), with the relationship of adolescent mothers ( 2=14.603, p=0.001), work ( 2=8.754, p=0.003), economic level ( 2=4.074, p=0.044) and education of the head of the family ( 2=8.754, p=0.003). In multivariate analysis was a higher risk for adolescent males (OR=1.292, 95%CI=1.038- 1.608), with lack of good... (Complete abstract click electronic access below)
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Alcoholism on the American Stage: De-Stigmatizing Socially Constructed Depictions of the Alcoholic through PerformanceCampbell, Thomas Michael 01 May 2013 (has links)
This dissertation seeks to address the societal problems associated with alcohol abuse and alcohol dependency in relationship to problematic depictions that have appeared on the American stage. It examines plays that perpetuate stigmas as well as plays that seek to subvert stigmas and stereotypical depictions as a means of creating avenues for discourse. This study asks how we, as practitioners of the theatre, can use the theatre and the act of storytelling to initiate empathy and compassion toward what is still considered a marginalized topic of discussion. Cultural misconceptions regarding the development of and (mis)understandings of alcohol abuse/dependency are perpetuated in our everyday lives, and theatre too often falls into the trap that perpetuates false ideas, which only furthers the stigmas and stereotypes associated with alcoholism. Preceded by a brief Introduction that sets the tone for this study, Chapter One offers medical information to delineate terms associated with alcohol use/abuse. UNIT TWO, presented in two chapters, offers analyses of seven plays: Thornton Wilder's Our Town, Eugene O'Neill's Long Day's Journey into Night, Christopher Durang's The Marriage of Bette and Boo, Theresa Rebeck's The Scene, Paula Vogel's How I Learned to Drive, Tracy Letts' August: Osage County, and Stephen Adly Guirgis' The Motherfucker With the Hat. Chapter Two focuses on the first four plays of this list and how each presents a particular problematic and/or stereotypical depiction of an alcoholic character(s) and/or alcohol use/abuse; Chapter Three focuses on the three remaining plays, which offer depictions and/or characters that trouble/complicate the stigmas associated with alcohol abuse/dependency. UNIT THREE is also cast in two chapters: Chapter Four looks at practices and theories used to enhance audience engagement and introduces companies who are using theatre to directly confront issues of alcoholism. Lastly, Chapter Five is a preface for my own full-length play (provided in Appendix A), which acts as my contribution to the ongoing conversations and efforts to diminish the stigmas and stereotypes within alcohol abuse/dependency. The dissertation concludes with a summary and a look at how open conversations regarding alcohol abuse/dependency can lead to empathy and understanding, bringing the topic out from the shadows in an effort to humanize the topic and the individuals and families who are struggling and suffering from alcohol abuse/dependency.
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Associação da suplementação de vitamina D3 e do alcoolismo experimental em ratos: efeitos morfológicos e comportamentais / Association of vitamin D3 supplementation and experimental alcoholism in rats: morphological and behavioral effectsPinto, Carina Guidi [UNESP] 22 January 2016 (has links)
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Previous issue date: 2016-01-22 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / Pró-Reitoria de Pesquisa (PROPe UNESP) / A ingestão de etanol compromete a estrutura do cérebro, apresentar efeitos bifásicos sobre a atividade motora, agindo como um estimulante ou depressor dependendo da dose ou a duração de utilização. Ele interfere na absorção e metabolismo de vitamina D3, o que se correlaciona com alguns distúrbios neurológicos e neuropsiquiátricos. Há relatos sobre a associação de etanol com alterações ósseas, incluindo baixos níveis de vitamina D3. Com base nisso, o objetivo deste estudo foi avaliar os efeitos em testes de comportamento da administração isolada de vitamina D3 ou a sua administração em associação com etanol, durante alcoolismo crônico. A fim de conseguir isso, foram utilizados dois grupos experimentais: ratos Wistar machos (n = 20) e ratos UChB linhagem machos (n = 20) (bebedores voluntários de etanol). Ambos os grupos foram divididos em dois subgrupos: Vitamina D3 - 12.5μg / kg / dia (500 UI) de colecalciferol (WV, n = 10, e UV, n = 10), e de controle (CC, n = 10, e UC, n = 10), durante um período de 75 dias. O peso corporal análises e testes de comportamento (reflexo de sobressalto acústico e campo aberto) foram realizados em 90 e 165 dias de idade. Além disso, os níveis de plasma de corticosterona foram medidos a 165 dias, sem diferença estatística entre os grupos experimentais. O grupo Wistar apresentou valores mais baixos ASR no momento final (Controle e completada), enquanto as percentagens PPI foram maiores no grupo inicial. No grupo UChB houve nenhuma diferença em percentagens PPI com o pré-estímulos utilizados. Quando as respostas ASR foram comparados entre os grupos (Wistar e UChB), o grupo UChB apresentaram menores amplitudes de ASR quando comparados com os animais do grupo de ratos Wistar. Em relação à PPI percentagens dos três estímulos pré utilizados no grupo UChB, as percentagens foram maiores em comparação com os animais do grupo de ratos Wistar, os valores ASR foi menor no grupo UChB. A presença de fezes e urina foi semelhante tanto nos momentos iniciais e finais, no teste de campo aberto, para todos os grupos experimentais. Considerando-se os outros parâmetros de campo aberto, diminuição da locomoção foi observado no grupo UChB no subgrupo vitamina D3, bem como no grupo de controlo final, em comparação com o controlo inicial. Quando os grupos Wistar e UChB foram comparados, este último apresentado taxas mais elevadas na locomoção. Os resultados obtidos estão em consonância com o efeito sedativo / depressivo de etanol sobre o sistema nervoso central, reduzindo a ASR de amplitude, com um aumento provável ao longo dos circuitos inibitórios que medeiam a PPI, a determinação do aumento na percentagem de inibição no grupo UChB, bem como um aumento na locomoção apresentada pelo grupo UChB no teste de campo aberto, caracterizada por uma diminuição no efeito aversivo ao novo ambiente. Além disso ressaltamos que a dose de vitamina D3 usado não teve efeito sobre o parâmetro de comportamento analisados, diferenças observadas neste grupo parecendo estar relacionada a se acostumar com a sonda gástrica. Este estudo descreve pela primeira vez na literatura as diferenças nas respostas ao teste acústico de sobressalto reflexo entre ratos Wistar e UChB, este último geneticamente predispostos a ingestão de etanol, uma linhagem adequada para ser usada em experiências compreendendo análises de comportamento em face da ingestão de etanol. / Ethanol intake compromises brain structure, presenting biphasic effects over motor activity, acting as a stimulant or depressor depending on the dose or duration of use. It interferes in vitamin D3 absorption and metabolism, what correlates to some neurologic and neuropsychiatric disorders. There are reports on the association of ethanol with bone alterations, including low levels of vitamin D3. Based on that, the objective of this study was to evaluate the effects in behavior tests of isolated administration of vitamin D3 or its administration in association with ethanol, during chronic alcoholism. In order to achieve that, two experimental groups were used: male Wistar rats (n=20), and UChB lineage male rats (n=20) (volunteer ethanol drinkers). Both groups were divided in two subgroups: Vitamin D3 – 12.5µg/kg/day (500 UI) of cholecalciferol (WV, n=10, and UV, n=10), and Control (WC, n=10, and UC, n=10), for a period of 75 days. Body weight analyses and behavior tests (acoustic startle reflex and open field) were conducted at 90 and 165 days of age. In addition to that, corticosterone plasma levels were measured at 165 days, with no statistical difference between the experimental groups. The Wistar group presented lower ASR values in the final moment (Control and supplemented), while the PPI percentages were higher in the initial group. In the UChB group there was no difference in PPI percentages with the pre-stimuli used. When the ASR responses were compared between groups (Wistar and UChB), the UChB group presented lower ASR amplitudes as compared to the animals of the Wistar group. In relation to PPI percentages in the three pre stimuli used in the UChB group, the percentages were higher as compared to the animals in the Wistar group, the ASR values been smaller in the UChB group. The presence of feces and urine was similar both in the initial and final moments, in the open field test, for all the experimental groups. Considering the other parameters of open field, decreased locomotion was noted in the UChB group in the vitamin D3 subgroup, as well as in the final control group as compared to the initial control. When the Wistar and UChB groups were compared, the latter presented higher rates in locomotion. The results obtained are consonant to the depressive/sedative effect of ethanol over the CNS, reducing ASR amplitude, with a likely enhancement over the inhibitory circuits which mediate PPI, determining the increase in inhibition percentage in the UChB group, as well as an increase in locomotion presented by the UChB group in the open field test, characterized by a decrease in the aversive effect to the new environment. In addition we emphasize that the dose of vitamin D3 used did not have effect over the behavior parameter analyzed, differences observed in this group seeming to be related to getting used to the gavage. This study describes for the first time in literature the differences in responses to the acoustic startle reflex test between Wistar and UChB rats, the latter genetically predisposed to ethanol intake, a lineage adequate to be used in experiments comprising analyses of behavior in face of ethanol intake. / PROPe/RENOVE: 0252/010/14
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Remodelação óssea do fêmur de ratas submetidas ao consumo de álcool e/ou à deficiência de estrógeno: análise imunoistoquímica e histomorfométrica / Bone remodeling in the femur of rats submitted to alcohol and/or estrogen deficiency: Immunohistochemical and histomorphometric analysisSalgado, Miriane Carneiro Machado [UNESP] 09 November 2016 (has links)
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Previous issue date: 2016-11-09 / Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) / O consumo excessivo de álcool constitui importante problema de saúde pública e possui ainda relação direta com a perda óssea mediante desequilíbrio da remodelação óssea, diminuição das taxas de reabsorção e também da osteogênese. A deficiência estrogênica também está diretamente associada à osteoporose, pois leva ao aumento da formação de osteoclastos e diminuição da síntese de osteoblastos, gerando um desequilíbrio no processo de remodelação óssea. A combinação de osteoporose e consumo de álcool pode ter efeito sinérgico e deletério sobre o tecido ósseo e tem sido objeto de estudos. O objetivo deste trabalho foi verificar possíveis alterações no metabolismo ósseo em fêmures de ratas submetidas ao alcoolismo crônico e deficiência estrogênica induzida por ovariectomia, por meio de análise histomorfométrica e imunoistoquímica. Foram utilizadas 90 ratas (Rattus norvegicus, variação albinus, Wistar) com 3 meses de idade, divididas em 6 diferentes grupos de igual número (15), conforme o tipo de dieta e quanto à presença ou ausência hormonal: Grupo 1: ovariectomia simulada (Sham), água e dieta livre; Grupo 2: Sham tratado com doses diárias de solução alcoólica a 20%; Grupo 3: Sham e alimentação isocalórica aos grupos associados ao álcool, fornecida por meio de solução aquosa de sacarose e dieta sólida; Grupo 4: ovariectomia, água e dieta sólida livre; Grupo 5: ovariectomia tratado com doses diárias de solução alcoólica a 20%; Grupo 6: ovariectomia e alimentação isocalórica semelhante ao grupo 3. Após 8 semanas do início da dieta, fez-se a eutanásia de todos os animais, e os fêmures foram removidos. A análise da dieta mostrou que o grupo Ovz dieta livre foi o que mais ganhou peso e o que mais ingeriu ração, apresentando diferenças significativas com relação aos demais grupos. Os animais dos grupos álcool consumiram em média 16 gramas de álcool por dia, sendo que o Sham álcool consumiu mais álcool, quando comparado ao Ovz álcool. Através da histomorfometria foi observado que os animais ovariectomizados apresentaram menor quantidade de osso trabecular em porcentagem, do que os sham operados, porém, sem diferença significativa. Os marcadores da remodelação óssea, RANKL, Osteoprotegerina e Osteocalcina, utilizados nas reações imunoistoquímicas, não mostraram alterações significativas no processo de remodelação óssea. Concluiu-se que ratas adultas jovens, esqueletalmente imaturas, submetidas ao alcoolismo crônico moderado, à remoção dos ovários ou à associação de ambos, mantêm as características de remodelação óssea cortical e trabecular do fêmur preservadas. / Excessive alcohol consumption is an important public health problem and also has direct relation with bone loss by imbalancing bone turnover. Estrogen deficiency is directly associated with osteoporosis, because it leads to an unequal bone resorption and formation by increased osteoclast formation and decreased synthesis of osteoblasts. The combination of osteoporosis and consumption of alcohol can have deleterious and synergistic effect on bone tissue and has been the subject of several studies. The objective of this study will be to investigate possible changes in bone metabolism in femurs of rats submitted to chronic alcoholism and estrogen deficiency induced by ovariectomy. We used 90 rats (Rattus norvegicus, Albinus variation, Wistar) with 3 months old. The animals were divided into six different groups of equal number, according to the type of diet and the presence or absence of hormones: Group 1: sham ovariectomized (sham), water and free diet, Group 2: Sham treated daily with alcoholic solution of 20% and feed ad libitum; Group 3: Sham isocaloric nutritional control group – treated with liquid diet containing sucrose with the same average calories ingested on the eve by the alcohol group and solid diet; Group 4: ovariectomy, water and solid diet free; Group 5: ovariectomy treated daily with alcoholic solution of 20% and feed ad libitum; Group 6: ovariectomy isocaloric nutritional control group like group 3. After 8 weeks from the beginning of the diet, all animals were sacrificed and femurs were removed. Diet analysis showed that the Ovx ad libitum was the group that ingested more feed and gained more weight, showing significant differences with the other groups. The animals of alcohol groups, consuming on average 16 grams of alcohol per day, Sham alcohol group consumed more alcohol, as compared to OVZ alcohol. Femurs were evaluated by histomorphometric analysis and immunohistochemical analysis, using the markers, RANKL, Osteoprotegerin and Osteocalcin. The histomorphometric analysis evidenced that ovariectomized animals showed, in percentage, a lower amount of trabecular, than the sham operated, but without significant differences. Markers of bone turnover in immunohistochemical reactions showed no significant changes in bone remodeling process. It was concluded that the combination of estrogen deficiency and moderate chronic alcohol consumption did not cause deleterious effects on bone remodeling of the femur of young adult rats. / FAPESP: 13/19517-13
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