Global ETD Search

71	Beta-lactamase mediated resistance in Escherichia Coli isolated from state hospitals in KwaZulu-Natal. Mocktar, Chunderika. January 2008 (has links) Escherichia coli, one of the most common pathogens causing urinary tract infections, has shown increased resistance to commonly used antibiotics. In this study we analyzed the β-lactamase profiles of 38 inhibitor-resistant E. coli isolates obtained from public hospitals at three different levels of healthcare in KwaZulu-Natal, selected on the basis of their resistance profiles to the three antibiotic/inhibitor combinations, viz., amoxicillin/clavulanate, ampicillin/ sulbactam and piperacillin/ tazobactam. The isolates were subjected to MIC determinations, IEF analysis, plasmid profile analysis, PCR of the different β-lactamase genes and sequencing thereof to detect the possible mechanism/s of resistance. A range of β-lactamases including two novel inhibitor-resistant TEM β-lactamases, TEM-145 and TEM-146 were detected in two isolates whilst a novel plasmid-mediated AmpC-type β-lactamase, CMY-20 was detected in three isolates. Other β-lactamases included OXA-1, TEM-55, SHV-2, CTX-M-l and TEM-1. Changes were detected in the chromosomal AmpC promoter/attenuator regions in one isolate. Diverse β-lactamase genes and plasmid profiles inferred extensive mobilization of β-lactamase genes causing the concern of limited therapeutic options in the face of increasing resistance. / Thesis (Ph.D.)-University of KwaZulu-Natal, Westville, 2008. Escherichia coli. Theses--Pharmacy and pharmacology. Beta-lactamases--Escherichia coli.
72	Experimental acute otitis media : aspects on treatment, protection and structural changes / Westman, Eva, January 2003 (has links) Diss. (sammanfattning) Umeå : Univ., 2003. / Härtill 4 uppsatser.
73	Antibiotic susceptibility and B-lactamase production of clinically isolated anaerobic bacteria / Siripan Wongwanich, Monthree Chulasamaya, January 1983 (has links) (PDF) Thesis (M.Sc. (Microbiology))--Mahidol University, 1983.
74	Expression, degradation, and applications of Escherichia coli TolA-beta-lactamase fusion proteins / Cooper, Kerri W. January 1998 (has links) Thesis (Ph. D.)--University of Washington, 1998. / Vita. Includes bibliographical references (leaves [80]-88).
75	Species specific susceptibility testing for [beta]-lactam antibiotics with special reference to staphylococci / Petersson, Ann Cathrine. January 1998 (has links) Thesis (doctoral)--Lund University, 1998. / Thesis statement on t.p. verso. Includes bibliographical references.
76	Study on b-lactamases in shigella flexneri isolated in Hong Kong and Shanghai / Siu, Leung-kei, Kris. January 1996 (has links) Thesis (Ph. D.)--University of Hong Kong, 1997. / Includes bibliographical references (leaf 129-150).
77	Spectrocopic [sic] and mechanistic studies on metallo-[Beta]-lactamase Bla2 from Bacillus anthracis Hawk, Megan J. January 2008 (has links) Thesis (M.S.)--Miami University, Dept. of Chemistry and Biochemistry, 2008. / Title from first page of PDF document. Non-Latin script record Includes bibliographical references.
78	Species specific susceptibility testing for [beta]-lactam antibiotics with special reference to staphylococci / Petersson, Ann Cathrine. January 1998 (has links) Thesis (doctoral)--Lund University, 1998. / Thesis statement on t.p. verso. Includes bibliographical references.
79	Characterization of L1, the metallo-B-lactamase from Stenotrophomonas maltophilia Garrity, James D. January 2004 (has links) Thesis (Ph. D.)--Miami University, Dept. of Chemistry and Biochemistry, 2004. / Title from second page of PDF document. Includes bibliographical references.
80	Characterization of the metallo-[beta]-lactamase L1 from Stenotrophomonas maltophilia Periyannan, Gopal Raj. January 2004 (has links) Thesis (Ph. D.)--Miami University, Dept. of Chemistry and Biochemistry, 2004. / Title from second page of PDF document. Includes bibliographical references.

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