1. INTRODUCTION Injuries of the lower cervical spine can be among the most devastating injuries of the musculoskeletal system because of the increased risk of the injury to the spinal cord, and also because they so often occur to the younger members of the population (Jones A.A.M. et al., 2003; Sekhon H.S.L. et al., 2001; Ball P.A., 2001). The cervical spine is the most vulnerable spinal segment (Sekhon H.S.L. et al., 2001). The mechanism of cervical spine trauma is defined by the direction and magnitude of the forces that have been applied externally to the head and neck complex resulting in injury (Allen B.L.Jr., 1982). Common injury vectors include flexion, compression, rotation and extension (Allen B.L.Jr., 1982). The pattern of injury is related not only to the external applied force, but also to the initial position or posture of the head and neck at the time of injury (Allen B.L.Jr., 1982). One pattern of these injuries of the lower cervical spine is a facet dislocations (Allen B.L.Jr., 1982). The facet dislocation of the cervical spine result from a hyperflexion injury of the neck (Allen B.L.Jr., 1982). These injuries are characterized radiographically by anterolisthesis of one cervical vertebrae over the other and include the slide anteriorly of the inferior facet of the upper dislocated vertebra over the superior facet of the vertebra below (Allen B.L.Jr., 1982; Razack N. et al., 2000). The facet dislocations of the lower cervical spine represent from 4% to 50% of... [to full text]

Whiplash injury is a common and troublesome disorder and approximately 10-40 per cent of its victims develop chronic symptoms. The annual incidence is estimated at 1/1000 inhabitants and the prevalence at 1%. The cause of chronic symptoms after whiplash injury is still unknown and no effective treatment has been presented so far. The present study is divided into two parts; the first part includes clinical, radiographic and psychological investigations, and the second part the effect of surgical intervention as well as intervention with medication. MRI studies (n=39) showed a larger proportion of pathologic findings compared to normal subjects, but no correlation with initial neurologic deficits was found. At the 2-year follow-up all patients with disc herniations with medullary impingement had persistent symptoms. Three patients had disc herniations that deteriorated from slight and moderate initial changes on the MRI to severe changes with medullary cord impingement. This deterioration might be a first sign of disc degeneration. Thus our results indicate that disc pathology is a contributing factor in the development of chronic symptoms. Measurements from standard lateral radiographs taken in neutral position were evaluated (n=48). A graphic digitizer connected to a microcomputer was used and the sagittal diameters were determined. Multivariate analysis of variance showed that the spinal canal was significantly smaller in patients with persistent symptoms indicating that a narrow spinal canal is unfavourable in patients subjected to whiplash injury. A psychological investigation (n=70) revealed no relationship between pre-existing personality traits and persistent symptoms. In our study, whiplash patients showed no differences in personality traits compared to normal controls. Our results after discectomy and anterior cervical fusion (n=20) because of chronic symptoms after whiplash injury were not satisfactory. We noticed that about half of the cases had less headache and neck pain but no beneficial effects on radicular pain, vertigo, visual and auditory symptoms were observed. Based on the criteria of a surgical evaluation, two patients were classified as good, nine as fair and nine as poor. A prospective randomised double-blind study of high-dose methyl-prednisolone compared to placebo was conducted (n=40). A clinical follow-up with repeated neurological examinations and a standardised questionnaire including VAS-scales and a pain sketch form were used for the evaluation of initial symptoms, before drug administration and at the follow-ups at 2 weeks, 6 weeks, and 6 months after the injury. At the 6-month follow-up there was a significant difference between the actively treated patients and placebo concerning disabling symptoms defined as inability to return to previous work, number of sick-days and sick-leave profile. All the actively treated patients had returned to work and none had multiple symptoms though three of them complained of intermittent neck pain. Our conclusion is therefore that acute treatment with high-dose corticosteroids might be beneficial to the prevention of disabling symptoms after whiplash injury. / <p>Härtill 6 uppsatser</p> / digitalisering@umu

Ziel dieser Arbeit ist die retrospektive Auswertung der operativ mit ventraler Dekompression und intersomatischer Fusion (ACDF) durch stand alone Cage versorgten Patienten und die Diskussion, ob eine postoperative Sinterung Einfluss auf das Outcome hat. Material und Methoden: Es wurden 33 Segmente operativ durch ACDF mit standalone-Cage bei 17 Patienten (11 Frauen und 6 Männer) Durchschnittsalter 56 Jahre (33 bis 82 Jahre) versorgt und nach durchschnittlich jeweils 8 und 26 Monaten klinisch, radiologisch und durch Scoreerhebung nachuntersucht. Ergebnisse: 70,6 % der Patienten (12/17) und 50,5% der Segmente (18/33) zeigten eine Sinterung. 36,3% der Sinterungen (12/33) bereits zur 1. NU nach 8 Monaten. Zur 2. NU nach 26 Monaten fand sich bei 100% eine Fusion ohne Pseudarthrose. Zusammenfassung: Die Sinterung des Cages hat keinen negativen Einfluss auf das Outcome. Wesentlich für das Outcome sind das Ausmaß und die Dauer der vorbestehenden Symptome. Es sollte besonders bei festgestellter Myelopathie frühzeitig eine operative Intervention erfolgen.

Injury to the human neck is a frequent consequence of automobile accidents and has been a significant public health problem for many years. The term `whiplash' has been used to describe these injuries in which the sudden differential movement between the head and torso leads to abnormal motions within the neck causing damage to its soft tissue components. Although many different theories have been proposed, no definitive answer on the cause of `whiplash' injury has yet been established and the exact mechanisms of injury remain unclear. Biomechanical research is ongoing in the field of impact analysis with many different experimental and computational methods being used to try and determine the mechanisms of injury. Experimental research and mathematically based computer modelling are continually used to study the behaviour of the head and neck, particularly its response to trauma during automobile impacts. The rationale behind the research described in this thesis is that a computational model of the human head and neck, capable of simulating the dynamic response to automobile impacts, could help explain neck injury mechanisms. The objective of the research has been to develop a model that_,, can accurately predict the resulting head-neck motion in response to acceleration impacts of various directions and severities. This thesis presents the development and validation of a three-dimensional computational model of the human head and cervical spine. The novelty of the work is in the detailed representation of the various components of the neck. The model comprises nine rigid bodies with detailed geometry representing the head, seven vertebrae of the neck and the first thoracic vertebra. The rigid bodies are interconnected by spring and damper constraints representing the soft-tissues of the neck. 19 muscle groups are included in the model with the ability to curve around the cervical vertebrae during neck bending. Muscle mechanics are handled by an external application providing both passive and active muscle behaviour. The major findings of the research are: From the analysis of frontal and lateral impacts it is shown that the inclusion of active muscle behaviour is essential in predicting the head-neck response to impact. With passive properties the response of the head-neck model is analogous to the response of cadaveric specimens where the influence of active musculature is absent. Analysis of the local loads in the soft-tissue components of the model during the frontal impact with active musculature revealed a clear peak in force in the majority of ligaments and in the intervertebral discs very early in the impact before any forward rotation of the head had occurred. For the case of rear-end impact simulations it has been shown for the first time that the inclusion of active musculature has little effect on the rotation of the head and neck but significantly alters the internal loading of the soft-tissue components of the neck.

The cervical spine must provide structural support for the head, allow large range of motion and protect both the spinal cord and branching nerves. There are two types of spinal joints: the intervertebral discs which are flexible connections and the facets, which are articulating synovial joints. Both types degenerate with age. Current surgical treatments include spinal fusion and articulating disc replacement implants. If both disc and facet joints are degenerated, fusion is the only option. In spinal fusion, the disc is removed and the adjacent vertebrae are fused which causes abnormally high stress levels in adjacent discs. In disc replacement, an articulating device is inserted to restore intervertebral motion and mimic healthy spinal kinematics. Disc arthroplasty does not significantly increase adjacent level stress but the lack of rotational constraint causes increased facet contact pressures. Thus, there is a need for a cervical total level arthroplasty system (CTLAS) that has a disc implant specifically designed to preserve the facet joints and implants for facet arthroplasty that can act independently or in-unison with the disc replacement. The conceptual design of a CTLAS implant system was proposed that would replace the disc and the facet joints. To facilitate medical imaging, PEEK (polyetheretherkeytone) was selected as the structural and bearing material. In the present thesis, multi-station pin-on-plate wear testing was initiated for pairs of unfilled (OPT) and carbon-fiber-reinforced (CFR) PEEK. Wear is important in arthroplasty implant design because wear particles can cause osteolysis leading to loosening. A variety of experiments were performed to investigate the effects of load, contact geometry and lubricant composition on wear. CFR PEEK was found to have much lower and more predictable wear than OPT PEEK in the present experiments. The wear of OPT PEEK pairs showed sensitivity to lubricant protein concentration. The coefficient of friction during testing was found to be quite high (up to 0.5), which might have clinical implications. Also, some subsurface fatigue was found, exposing carbon fibers of CFR PEEK. This remains a concern for its long-term application. Further wear testing is recommended using actual implants in a spine wear simulator.

The cervical spine ligaments play an essential role in limiting the physiological ranges of motion in the neck; however, traumatic loading such as that experienced in automotive crash scenarios can lead to ligament damage and result in neck injury. The development of detailed finite element models for injury simulation requires accurate ligament mechanical properties at relevant loading rates. The objective of this research was to provide detailed mechanical properties for the cervical spine ligaments, by performing tensile tests at elongation rates relevant to automobile crash scenarios, using younger specimens (less than 50 years old), and to provide a comprehensive investigation of spinal level and gender effects. The five primary ligaments (present between C2-T1) investigated were: the anterior longitudinal ligament, posterior longitudinal ligament, capsular ligament, ligamentum flavum, and interspinous ligament. The craniovertebral ligaments (Skull/C0-C2) investigated were the tectorial membrane/vertical cruciate/apical/alar ligament complex, transverse ligament, anterior atlanto-occipital membrane, posterior atlanto-occipital membrane, anterior atlanto-axial membrane, and posterior atlanto-axial membrane. Tests were performed within an environmental chamber designed to mimic in vivo temperature and humidity conditions, and specimens were preconditioned for 20 cycles at 10% strain prior to testing to failure. Ligaments were tested at quasi-static (0.5s-1), medium (20s-1) and high (150-250s-1). These strain rates were predicted by an existing cervical spine finite element model under typical crash scenarios. Two hundred sixty-one total primary ligament tests were performed, with approximately even distribution within elongation rate, spinal level, and gender. Another forty-four craniovertebral ligaments were tested. Results were plotted as force-displacement curves and the response characteristics determined from the curves were: failure force, failure elongation, stiffness of the linear region, toe region elongation, failure stress, failure strain, modulus and toe region strain. The measured force-displacement data followed expected trends when compared with previous studies. The younger ligaments had less scatter, and were both stiffer and stronger than the older specimens that were reported in previous studies at both quasi-static and comparable higher elongation rates. Statistical analysis was performed on the results to establish significant effects. Strain rate effects were most significant whereas spinal level effects were not found. In general, gender effects were not found to be significantly different, but consistent trends were identified with male ligaments having a higher stiffness and failure force than female ligaments. The post-ultimate load region of the curves was reported to offer insight into the ligament failure mechanism. The characteristic values obtained were used to develop average curves for each ligament, with the intention to eventually be directly integrated into finite element models to better represent the ligament structures. Curves were developed to incorporate the strain rate, spinal level and gender effects for each ligament based on the statistical analyses. Post-failure response was incorporated into these curves because this region has been shown to have an effect on neck behaviour in mathematical models. Recommendations for future studies include measuring accurate cross sectional areas of ligaments during tensile testing to obtain true stress and true strain measurements to better understand if differences in mechanical properties are structural or material. Other possible improvements would be further testing of young cervical spine ligaments with larger sample sizes to further explore spinal level and gender effects. Additional testing performed under identical testing conditions as the current study would allow for pooling of the results effectively increasing the sample size.

Im Rahmen der szintigraphischen Untersuchung der Halswirbelsäule gibt es unterschiedliche Aussagen zum physiologischen Speicherungsverhalten, insbesondere der kaudalen Facettengelenke. Eine Objektivierung der Szintigramme und Ermittlung von Normalbereichen der entsprechenden Speicherquotienten ist daher wichtig und stellt das Ziel dieser Arbeit dar. Zur Untersuchung kamen dafür 31 Pferde, bei denen es sich um Patienten der Chirurgischen Tierklinik in Leipzig aus dem Jahr 2008 handelte. Falls bei einem Pferd eine Lahmheit der Vordergliedmaße vorhanden war, wurde mit Hilfe der klinischen und szintigraphischen Untersuchung, sowie mittels diagnostischer Anästhesien als deren Ursache die Halswirbelsäule ausgeschlossen. Alle Pferde wiesen eine freie Beweglichkeit des Halses in alle Richtungen auf. Zur Bildung von Speicherquotienten wurden die als Interessenareale dienenden Facettengelenke C3/C4 bis C7/Th1, sowie der Wirbelkörper des sechsten Halswirbels zu verschiedenen Referenzarealen ins Verhältnis gesetzt. Als Referenzareale wurden dabei der Wirbelkörper des dritten und des vierten Halswirbels, sowie das auch als Interessenareal dienende Facettengelenk C3/C4 getestet. Anschließend wurden Normalbereiche für die Speicherquotienten ermittelt. Nach sonographischer Muskeldickenmessung über den Facettengelenken wurden deren Speicherquotienten mit Hilfe einer Formel auf einen Nullwert korrigiert, und für diese korrigierten Werte wurden ebenfalls Normalbereiche ermittelt. Es zeigte sich, dass die Speicherquotienten nach der Muskeldickenkorrektur gegenüber den nativen Speicherquotienten eine größere Streuung aufwiesen und somit größere und ungenauere Normalbereiche hervorbrachten. Dementsprechend sollten die nativen Speicherquotienten bevorzugt werden. Als das am besten geeignete Referenzareal für die Interessenareale C4/C5 bis C7/Th1 erweist sich hierbei die Isokontur-ROI auf dem Facettengelenk C3/C4. Für das Interessenareal C3/C4 eignet sich sowohl der Vergleich mit dem Referenzareal C3, als auch der mit dem Referenzareal C4. Das Interessenareal auf dem Wirbelkörper C6 wird am besten zum Referenzareal C4 ins Verhältnis gesetzt. Hervorzuheben sind die nativen Werte der Normalbereiche für die Gelenke C5/C6 und C6/C7, da hier am häufigsten röntgenologische Veränderungen zu finden sind. Sie betragen für das Gelenk C5/C6 auf der linken Halsseite 0,82-1,10 und auf der rechten Halsseite 0,86-1,10. Für das Gelenk C6/C7 beträgt der Normalbereich für die linke Halsseite 0,75-1,23 und für die rechte Halsseite 0,81-1,17. Zusammenfassend ist zu sagen, dass die quantitative Auswertung mittels der „Regions of Interest“-Technik an der Halswirbelsäule durchaus möglich ist und mit dieser Arbeit akzeptable Normalbereiche für die Facettengelenke C3/C4 bis C7/Th1 und für den Wirbelkörper C6 ermittelt werden konnten. Es fehlen nun noch Werte von Pferden mit einer klinischen Halswirbelsäulenproblematik, um die Aussagekraft der hier ermittelten Normalbereiche zu überprüfen.

The research described in this thesis focuses on the biomechanics of cervical spine injury diagnosis and rehabilitation management. This research is particularly relevant to the diagnosis of minor neck injuries that typically arise from motor vehicle accidents and are classified as "whiplash injuries". The diagnosis and treatment of these chronic neck problems has been particularly difficult and frustrating and these difficulties prompted calls for the objective evaluation of the techniques and procedures used in the measurement and assessment of neck dysfunction. The biomechanical aspects of the clinical diagnosis of minor cervical spine injuries were investigated in this work by reconfiguring an existing detailed biomechanical model of the human neck to simulate injuries to particular structures, and to model abnormal muscle activation. The investigation focused on the range of motion assessment and the methods of testing and rehabilitating the function of the deep neck muscles because the model could be applied to provide further insight into these facets of neck injury diagnosis and management. The de Jager detailed head-neck model, available as a research tool from TNO (The Netherlands), was chosen for this study because it incorporated sufficient anatomical detail, but the model required adaptation because it had been developed for impact and crash test dummy simulations. This adaptation significantly broadened the model's field of application to encompass the clinical domain. The facets of the clinical diagnosis of neck dysfunction investigated in this research were range of motion and deep muscle control testing. Range of motion testing was simulated by applying a force to the head to generate the primary motions of flexion/extension, lateral flexion and axial twisting and parametric changes were made to particular structures to determine the effect on the head-neck movement. The main finding from this study of cervical range of motion testing was that while motion can be accurately measured in three dimensions, consideration of the three dimensional nature of the motion can add little to the clinical diagnosis of neck dysfunctions. Given the non-discriminatory nature of range of motion testing, the scientific collection and interpretation of the three dimensional motion patterns cannot be justified clinically. The de Jager head-neck model was then further adapted to model the cranio-cervical flexion test, which is used clinically to test the function of the deep muscle groups of the neck. This simulation provided confirmation of the efficacy of using a pressure bio-feedback unit to provide visual indication of the activation of the deep flexor muscles in the neck. However, investigation of the properties of the pressure bio-feedback unit identified significant differences in the stiffness of the bag for the different levels of inflation that must be accounted for if comparisons are to be made between subjects. Following the identification of the calibration anomalies associated with the pressure bio-feedback unit, the motion of the point of pressure of the head on the headrest and the force at this point of contact during the activation of the deep flexor muscle group were investigated as an alternative source of feedback. This output, however, was found to be subject specific, depending on the posterior shape of the skull that determined the point of contact during the head rolling action. Clinically, an important outcome of the alternative feedback assessment was that the prescribed action to target the deep flexor muscle group will feel different for each individual, ranging from a slide to a roll of the head on the headrest, and this must be accounted for when explaining the action and during rehabilitation management.

Thesis (MScEng (Industrial Engineering))--Stellenbosch University, 2008. / In the context of intervertebral disc replacement and customized implants, human simulation studies are of great importance. Simulation models need input data. This study investigated different in vivo motion capturing methods to capture spinal kinematics that will serve as input for simulation models. Available scanning and motion capturing techniques for capturing cervical kinematics range from simple clinical methods, to expensive specialized equipment and software. With a variety of technologies comes a variety of applications. In this study the focus is on capturing the kinematics of the cervical spine. An important distinction was made between two types of motion capturing technologies: external motion capturing and internal imaging technologies. The available external motion capturing technologies pose many advantages in terms of cost, safety, simplicity, portability and producing accurate three dimensional position and orientation. However, the ability for external motion capturing technologies to give accurate information on the movements at each vertebral level is doubted by critics reasoning that the true vertebral motion is concealed by the skin and soft tissue. Although it would be ideal to use external motion capturing systems, one needs to be confident that these surface markers or sensors truly reflect the vertebral motion at each vertebral level. An empirical study was conducted to evaluate the relationship between motion captured on the skin surface and motion of the vertebrae. Twenty-one subjects received low dosage X-rays, while radio opaque markers were attached to the skin at each respective vertebral level. The motion of external markers and that of the vertebrae could be seen simultaneously on one medium. In the empirical study, two outputs were achieved. Firstly, intervertebral kinematic data, for use in further simulation studies was obtained. Secondly, the relationship between surface markers and vertebrae in different motion instances was investigated. Distance and angle parameters were constructed for vertebral prediction from skin surface markers. The causes of variation in these parameters were identified by investigating the correlations of these parameters with anthropometrical variables. Strong correlations of the parameters were observed in flexion, but in extension, especially full extension, the correlations were poor to insignificant. It was concluded that in neutral, half flexion and full flexion it is possible to predict the vertebral position from surface markers by using the parameters and anthropometrical variables. In half extension this prediction would be less accurate and in full extension alternative methods should be investigated for external motion capturing.

Elevados índices de dor cervical e lombar têm sido reportados em ciclistas. Fatores como a postura adotada na bicicleta, a ativação dos músculos extensores da coluna e a ação de cargas mecânicas nas estruturas da coluna tem sido apontados como possíveis causas da dor. Embora relatados e aparentemente aceitos, poucos estudos objetivaram investigar estes fatores. Em adição, a dor crônica não específica é frequentemente diagnosticada em ciclistas, pois poucas evidências de anormalidade são observadas quando realizados exames radiológicos clínicos. O emprego de métodos biomecânicos de investigação, como a estimativa da magnitude da força muscular dos extensores da coluna e da força articular em diferentes níveis da coluna poderia contribuir para avaliação do risco de lesão e dor em decorrência do ciclismo, além de auxiliar na criação de estratégias de prevenção e programas de reabilitação. Assim, este estudo teve como objetivo quantificar e comparar as forças internas atuantes na coluna cervical durante o ciclismo em diferentes posturas, por meio do desenvolvimento e aplicação de um modelo biomecânico tridimensional in vivo. O modelo biomecânico proposto foi composto por dois segmentos rígidos (coluna cervical superior e inferior) conectados. O segmento coluna cervical superior compreende a cabeça, C1 e C2. O segmento coluna cervical inferior compreende as vértebras cervicais de C3 a C7. No segmento coluna cervical superior são considerados dois vetores de força muscular: FM1 (rectus capitis posterior major, rectus capitis posterior minor, obliquus capitis superior e obliquus capitis inferior) e FM2 (semispinalis capitis e splenius capitis). Já no segmento coluna cervical inferior estão inclusos os vetores FM3 (semispinalis cervicis) e FM4 (splenius cervicis). A resolução das equações de movimento de Newton-Euler é realizada por meio da solução inversa. Os parâmetros cinemáticos foram obtidos utilizando imagens externas da cabeça e coluna cervical, adquiridas por meio de quatro câmeras de vídeo digital com frequencia de amostragem de 25 Hz. Para estimar a localização dos centros de rotação (C2-3 e C6-7) foram realizados exames radiológicos convencionais estáticos. Os parâmetros de massa e centro de massa foram retirados de tabelas antropométricas da literatura. Participaram do estudo 12 ciclistas com pelo menos dois anos de experiência competitiva cada. O estudo foi aprovado pelo Comitê de Ética em Pesquisa da Universidade Federal do Rio Grande do Sul e os sujeitos assinaram um termo de consentimento livre e esclarecido. Cada participante foi avaliado utilizando sua própria bicicleta acoplada a um ciclossimulador magnético, em duas etapas realizadas no mesmo dia. Inicialmente foi mensurada a massa corporal total do individuo e em seguida identificados e marcados 14 pontos anatômicos de interesse com uma caneta dermatográfica. Durante as avaliações foram fixos marcadores revestidos com papel reflexivo e contendo chumbo no interior em todos os pontos anatômicos de interesse. Na Etapa I os sujeitos pedalaram durante 2 minutos em cada postura (ereta, descanso, intermediária, ataque e cotovelos flexionados), sendo coletados dados cinemáticos durante os últimos 30 segundos de cada uma. Na Etapa II foram realizados exames radiológicos estáticos em cada uma das 5 posturas analisadas (ereta, descanso, intermediária, ataque e cotovelos flexionados) e em flexão e extensão máximas da coluna cervical. Os resultados indicam que as forças internas atuantes nas estruturas da coluna cervical apresentaram maiores magnitudes nas posturas que envolvem a prática do ciclismo (descanso, intermediária, ataque e cotovelos flexionados), quando comparadas a postura de referência (ereta). Observando somente as posturas que envolvem o ciclismo, as forças internas aumentaram gradativamente a medida que os ciclistas transferiram o apoio de suas mãos da região superior para a região inferior do guidão, adotando as posturas descanso, intermediária e ataque, respectivamente. Entretanto, as maiores magnitudes das forças internas foram observadas quando os ciclistas efetuaram o apoio das mãos envolvendo os manetes e flexionaram a articulação do cotovelo (postura cotovelos flexionados). Proporcionalmente os maiores aumentos das forças internas ocorreram na coluna cervical superior, porém as maiores magnitudes das forças internas foram alcançadas na coluna cervical inferior. O processo de avaliação demonstrou que o modelo biomecânico tridimensional da coluna cervical proposto foi considerado capaz de representar de maneira confiável o sistema de interesse. Os resultados encontrados são coerentes, sendo o modelo um instrumento adequado para estimar as forças internas atuantes na coluna cervical durante o ciclismo em diferentes posturas. / High index of cervical and lumbar pain had been registered in cyclists. Factors as a posture adopted on bicycle, the activity of spine extensor muscles and the action of mechanical load in the spine structures had been put like possible causes of pain. Although related and apparently accepted, few studies investigate these factors. In addition, the non-specific chronic pain is frequently diagnosed in cyclists, because few evidences of abnormalities are investigated when clinic radiologics exams are done. The use of biomechanical methods of investigation, like the estimate of muscular force magnitude of extensors of spine and of joint force in different levels of spine can be contributed to evaluation of injury risk and pain caused by cycling, beyond the assist in strategies of prevention and rehabilitation programs. Therefore, this study had like objective to quantify and compare the active internal forces in the cervical spine during cycling in different postures, through development and application of three dimensional in vivo biomechanical model. The biomechanical model suggested was compound by two rigid segments (upper and lower cervical spine) connected. The upper cervical spine segment include head, C1 and C2. The lower cervical spine segment include cervical vertebraes of C3 to C7. In the upper cervical spine segment are considered two vectors of muscular force: FM1 (rectus capitis posterior major, rectus capitis posterior minor, obliquus capitis superior e obliquus capitis inferior) and FM2 (semispinalis capitis e splenius capitis). In the lower cervical spine segment are included the vectors FM3 (semispinalis cervicis) and FM4 (splenius cervicis). The resolution of movement equation of Newton-Euler is done through inverse dynamics. The kinematic parameters were obtained using external images of head and cervical spine, acquired by four digital video cameras with sampling frequency of 25 Hz. To estimate the location of rotation centers (C2-3 and C6-7) statics conventional radiologic exams were done. The parameters of mass and center of mass were removed of anthropometric tables of literature. 12 cyclists with at least two years of competitive experience each one participated of the study. The study was approved by Ethics Committee in Researches of Federal University of Rio Grande do Sul and the subjects signed a free and clear consent term. Each participant was assessed using your bicycle attached in a magnetic cycle simulator, in two stages done in the same day. Initially the total body mass of subjects was measured and then 14 anatomic points of interest were identified and marked with a dermatography pen. During the evaluation markers encased with reflective paper and containing lead inside of these markers were fixed in all anatomic points of interest. In the stage I the subjects rode a bicycle during 2 minutes in each posture (upright neutral, rest, intermediate, attack and flexed elbows). The kinematic data were collected during the last 30 seconds of each one. In the stage II static radiologic exams were done in each of 5 analyzed postures (upright neutral, rest, intermediate, attack and flexed elbows) and in maxim flexion and extension of cervical spine. The results indicate that the internal forces active in the structures of cervical spine presented more magnitudes in the postures that involve the cycling practice (rest, intermediate, attack and flexed elbows), when compared to reference posture (upright neutral). Observing just the postures that involve the cycling, the internal forces gradually increased as cyclists transferred the your hands from upper to lower region of handlebar, adopting the rest, intermediate and attack postures, respectively. However, the greater magnitude of internal forces were observed when the cyclists hands involving the brake levers and flexed the elbow joints (flexed elbows posture). Proportionally the greatest increase of internal forces occurred in the upper cervical spine, however the greatest magnitudes of internal forces were reached in the lower cervical spine. The evaluation process demonstrated that the three dimensional biomechanical model of cervical spine was considered able to represent of reliable way the interest system. The results found are coherent, the model is an adequate instrument to estimate the internal forces active in the cervical spine during cycling in different postures.