published_or_final_version / abstract / toc / Clinical Psychology / Master / Master of Social Sciences

Die Single Port-Operationsmethode stellt eine neue Technik auf dem Gebiet der Minimal-invasiven Chirurgie dar. Hierbei werden operative Eingriffe über nur einen Zugang durchgeführt. Über diese Minimalisierung des Zugangstraumas werden die Ziele eines besseren kosmetischen Ergebnisses durch weniger und kleinere Narben, einer schnelleren Rekonvaleszenz mit kürzerer Hospitalisierung und einer daraus resultierenden höheren Patientenzufriedenheit verfolgt. In dieser Arbeit wurde diese Operationsmethode anhand von Patienten evaluiert, die sich einer Cholecystektomie oder einer Adrenalektomie in Single Port-Technik am Klinikum St. Georg in Leipzig unterzogen. Zur Analyse der potentiellen Vor- und Nachteile dieser Methode wurden die intra- und postoperativen Daten der Patienten retrospektiv ausgewertet und es fanden Nachuntersuchungen statt. Im Rahmen dieser Nachuntersuchungen wurde das kosmetische Ergebnis der Operationsnarben anhand der Vancouver Scar Scale beurteilt. Weiterhin kam zu der Beantwortung zweier Fragebögen durch die Patienten, bei denen die postoperative Lebensqualität und die subjektive Patientenzufriedenheit ermittelt wurde. In der Auswertung aller Ergebnisse zeigte sich, dass es sich bei dem Single Port-Verfahren innerhalb unseres Patientenkollektivs um eine gut durchführbare und sichere Technik handelt, die mit einem verbesserten kosmetischen Ergebnis und einer sehr hohen Patientenzufriedenheit einhergeht. Nachteilig steht dem eine derzeitig noch signifikant längere Operationszeit, bedingt durch die anspruchsvollere operative Handhabung und die höheren Materialkosten gegenüber.

Thesis (M.S.)--University of Michigan, 1972.

Background: Opioid abuse has become a serious public health issue. While adequate pain management is an ethical responsibility for health care providers, responsible stewardship of controlled substances is of equal concern. Opioids are often prescribed for treatment of acute pain post-operatively. The purpose of this study is to examine opioid prescription practices and use of opioids after laparoscopic cholecystectomy. Methods: A convenience sample of 42 patients scheduled for laparoscopic cholecystectomy were enrolled in the study. Using a descriptive study design, patients were interviewed by phone 6-10 days post-operatively using a scripted questionnaire. The average number of excess prescribed opioid medication pills, patient perception of prescribed quantity, duration of opioid use, and average pain score with and without activity on the date of contact was determined. Participants were also asked about any instruction received regarding proper medication disposal. Results: A final sample of 34 patients met inclusion criteria and completed the phone questionnaire. Average number of excess pills ranged from 0-42 (M:14; SD 11.7). Nearly half of patients (47%) perceived the prescribed quantity as 'too many', 41% indicated the prescription quantity was 'just right' but many had left-over pills, and 11.8% believed the prescribed quantity to be 'too few'. The average number of days of opioid use following surgery was 4.2 days with 71% of patients using opioids for five or fewer days. The average pain score at the time of the interview was 2.0 without activity, and 4.1 with activity. Almost all (88%) patients did not recall any instruction or knowledge of appropriate medication disposal. A few participants volunteered plans to dispose of unused medications by various means, while others indicated they planned to keep excess pills. Conclusion: Pain management experts advise using around-the-clock regimens of over-thecounter analgesics (i.e. acetaminophen or non-steroidal anti-inflammatory medication (NSAID)) and using opioids sparingly as an adjunct therapy following uncomplicated laparoscopic cholecystectomy. The data in this study indicated currently prescribed opioid quantities after laparoscopic cholecystectomy are more than adequate and could be decreased without affecting adequate pain management. In addition, the data show a large majority of patients are not provided with personalized instruction on proper medication disposal procedures.

Massive bilateral adrenal hemorrhage occurring in the postoperative period is an unusual but potentially life-threatening complication of any abdominal operation. The diagnosis is often difficult due to the nonspecific nature of the clinical presentation, which is easily attributable to other more common postoperative conditions. We report a case of bilateral adrenal hemorrhage resulting in acute primary adrenal insufficiency following an otherwise-uncomplicated laparoscopic cholecystectomy, which has not previously been described. An awareness of the possibility of this uncommon condition complicating laparoscopic cholecystectomy may lead to a higher index of suspicion, which is important in timely diagnosis and prompt treatment.

Thesis (M.S.)--University of Michigan, 1999. / Includes bibliographical references.

Thesis (M.S.)--University of Michigan, 1999. / Includes bibliographical references.

published_or_final_version / Community Medicine / Master / Master of Public Health

O uso da Estimulação Elétrica Transcutânea do Nervo (TENS) vem sendo muito pesquisado em pós-operatórios, todavia os estudos não analisam se a TENS de baixa freqüência -- que estimula a liberação de opióides endógenos -- seria eficiente em promover analgesia preemptiva. Objetivo. Analisar se essa modalidade de TENS, aplicada antes de colecistectomias por laparotomia, poderia proporcionar analgesia preemptiva. Casuística e método. A pesquisa -- clínica, controlada, randomizada e duplamente encoberta -- foi realizada no Hospital São Domingos Sávio, e teve uma amostra de 50 pacientes, todas do sexo feminino: grupo preemptivo (n = 25) e placebo (n = 25). As pacientes do primeiro grupo foram submetidas à aplicação da TENS de baixa freqüência antes da cirurgia: e as do grupo placebo, a uma falsa estimulação. Houve a padronização do cloridrato de bupivacaína (0,5%) como droga anestésica, associado ao fentanil (2 ml) para a realização das colecistectomias; e da medicação analgésica utilizada no pós-operatório: dipirona, prescrita de 6 em 6 horas, e diclofenaco de sódio, como medicação de resgate. A intensidade de dor pós-operatória foi mensurada pela Escala Numérica de Mensuração da Dor (END), em 8 momentos (2½, 3½, 4½, 5½, 7, 8 e 16 horas após a indução do bloqueio anestésico, além de uma última verificação no momento da alta hospitalar), e pelo Questionário de Dor McGill (MPQ), aplicado 16 horas após a indução do bloqueio anestésico. Outrossim, o grau de satisfação das pacientes com o tratamento foi mensurado pela Escala de Satisfação do Paciente (ESP). Os dados foram analisados por meio de testes estatísticos descritivos, Teste de Mann-Whitney, Teste-t de Student para amostras não-pareadas e qui-quadrado, sendo o nível de significância de 5%. Resultados. A intensidade de dor, mensurada pela END, foi significantemente menor no grupo preemptivo nas terceira e quarta coletas. Não houve diferença significante quanto aos índices obtidos pelo MPQ, e nem quanto à satisfação das pacientes, o consumo de drogas analgésicas no pós-operatório e o tempo para o primeiro requerimento de diclofenaco de sódio. Conclusão. A TENS de baixa freqüência proporcionou analgesia preemptiva após colecistectomia por laparotomia. / Introduction. Transcutaneous Electrical Nerve Stimulation (TENS) has been searched in the postoperative period, however these studies don\'t analyze whether low frequency TENS -- that stimulates the release of endogenous opioids -- could be efficient to provide preemptive analgesia. Objective. The aim of this study was to verify whether low frequency TENS, applied before open cholecystectomies, could provide it. Cases and method. It was a controlled, randomized and double-blinded trial, carried out at the Hospital São Domingos Sávio (Aracaju city, Brazil), and had a sample of 50 patients: preemptive group (n = 25) and placebo (n = 25). The patients from the first group were submitted to the application of TENS before the surgery; and the placebo group to a false stimulation. There was the standardization of the bupivacaine (0,5 %) as anesthetic drug plus fentanyl (2 ml) for the accomplishment of the cholecystectomies; and of the analgesic medication used in the postoperative period: dipyrone, prescribed for every 6 hours, and diclofenac, only if the patients complained about pain. Pain intensity was measured by the Numerical Rating Scale (NRS), in 8 moments (2½, 3½, 4½, 5½, 7, 8 e 16 hours after inducing the anesthesia besides one last verification at the hospital discharge), and by the Brazilian version of the McGill Pain Questionnaire (Br-MPQ), applied 16 hours after inducing the anesthesia. Patient satisfaction level in relation to the treatment was measured by the Patient Satisfaction Scale (PSS). The data were analyzed by Mann-Whitney Test, unpaired t-test and qui-square, being significant, those data with p < 0,05. Results. Pain intensity, measured by the NRS, was lower in the preemptive group in the third and fourth verifications. There was no difference neither in relation to the indexes obtained with the Br-MPQ, nor the PSS, consume of analgesics in the postoperative and time for the first request of diclofenac. Conclusion. Low frequency TENS provided preemptive analgesia after open cholecystectomy.

Bakgrund: Att förebygga och behandla postoperativ smärta är anestesisjuksköterskans ansvar genom det perioperativa förloppet. Tidigare studier har visat att förekomsten av postoperativ smärta efter laparoskopisk kolecystektomi är hög. Syfte: Syftet med studien var att beskriva postoperativ smärtskattning hos patienter som genomgått laparoskopisk kolecystektomi på en sluten operationsavdelning och en dagkirurgisk operationsavdelning. Syftet var också att undersöka skillnader i förekomst av postoperativ smärta mellan män och kvinnor, yngre och äldre patienter samt mellan patienter som opererats på sluten- respektive dagkirurgisk operationsavdelning. Metod: Studien var en retrospektiv registerstudie med kvantitativ ansats. Registerdata innehållande data från 338 patienter inhämtades från kvalitetsregistret Svenskt Perioperativt Register från år 2016–2018. Materialet analyserades med beskrivande och jämförande statistik. Resultat: Resultatet visade att 70 % av patienterna skattade måttlig till svår postoperativ smärta (NRS 4-10). Det framkom även att kvinnor samt yngre patienter (&lt;50 år) på den dagkirurgiska operationsavdelningen skattade signifikant högre postoperativ smärta jämfört med män och äldre patienter. Slutsatser: Även om inga generella slutsatser kan dras tyder resultaten på att kvinnor samt patienter 50 år och yngre är särskilt utsatta för otillräcklig smärtbehandling i samband med laparoskopisk kolecystektomi. Eftersom alla människor har rätt till god smärtlindring behöver omvårdnaden således anpassas efter patientens individuella förutsättningar och behov. När anestesisjuksköterskan når en förtrolig relation till patienten finns goda förutsättningar för en tillfredställande postoperativ omvårdnad.