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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
41

Chronic Pelvic Pain in Men

Hakenberg, Oliver W., Wirth, Manfred P. January 2002 (has links)
Chronic pelvic pain is a condition which receives less attention in men than in women. It is often difficult to diagnose and more difficult to treat. The new classification of prostatitis and its variants has introduced the term ‘chronic pelvic pain syndrome’ which underlines the difficulties in dealing with this disorder which may represent a variety of chronically painful conditions with a large functional component. / Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
42

Patientupplevelser av kronisk bäckenbottensmärta - En litteraturöversikt / Patient experiences of Chronic Pelvic Pain Syndrome - A literature review

Gleasure, Charlie, Zhao, Yiqiao January 2022 (has links)
Bakgrund: Aktuell forskning om kroniskt bäckenbottensmärtsyndrom (CP/CPPS) visar brist på behandlingsalternativ som adekvat lindrar symtomen. Män och kvinnor med diagnosen CP/CPPS upplever vanligtvis ett långvarigt symtomförlopp som uppkommer både fysiskt och mentalt. CP/CPPS påverkar patientens livskvalitet och diagnosen i sig påverkas av sjuksköterskan och sjuksköterskans roll inom den personcentrerade vården. Metod: En litteraturöversikt av kvalitativ ansats genomfördes för att analysera kvalitativa intervjudata som avsåg patientupplevelser av CP/CPPS.Resultat: Analysen resulterade i fyra teman: Patienter med en CP/CPPS-diagnos upplever svårigheter i sina sexuella relationer; Patienter upplever ofta en känslomässig påverkan på grund av CP/CPPS-relaterade symtom såsom ångest eller katastroftänkande; CP/CPPS orsakar social isolering som påverkar patienternas dagliga liv; Vårdrelaterade känslor av hjälplöshet och hopplöshet upplevs av CP/CPPS-patienter där patienter känner att deras problem inte ses eller hörs av medicinska leverantörer, vilket får dem att känna en brist av kontroll över sina liv. Konklusion: Patientupplevelser av CP/CPPS manifesteras negativt, vilket resulterar i en minskning av livskvalitet. För att kunna förstå och försöka hjälpa patienten i sin kamp med CP/CPPS, krävs först en förförståelse för hur de negativa manifestationerna av CP/CPPS flätas samman och förvärras genom en ömsesidig påverkan. / Background: Current research about Chronic Pelvic Pain Syndrome (CP/CPPS) shows a lack of treatment options that give adequate results. Men and women diagnosed with CPPS usually experience a long course of symptoms which manifest in different ways, both physically and mentally. CP/CPPS has strong ties to patient quality of life and the diagnosis is impacted by the nurse and the nurse’s role within person-centred care. Method: A literature review was carried out to analyse qualitative interview data that pertained to patient experiences of CP/CPPS. Results: The analysis resulted in four themes: Patients with a CP/CPPS diagnosis experience difficulties in their sexual relationships; Patients often experience an emotional impact due to CP/CPPS related symptoms such as anxiety or catastrophic thinking; CP/CPPS causes social withdrawal which impacts patients’ daily life; Care-related helplessness and hopelessness are experienced by CP/CPPS patients whereby patients feel that their issues were not being seen or heard by medical providers which caused them to feel a loss of control over their lives. Conclusion: Patient experiences of CP/CPPS manifest themselves negatively and have an impact on a patient’s well-being, life world and even relationships both personal and within care. To understand and attempt to aid patients in their struggle with CP/CPPS, there first requires a pre-understanding of how the negative manifestations of CP/CPPS intertwine and exacerbate one another.
43

CCL2 (MCP-1) MEDIATES CHRONIC PELVIC PAIN THROUGH MAST CELLS IN EXPERIMENTAL AUTOIMMUNE CYSTITIS

Bicer, Fuat 28 August 2012 (has links)
No description available.
44

Expressão do fator de crescimento neuronal (FCN), do seu receptor (trk A) e dos receptores de estrogênio e progesterona no peritôneo pélvico em mulheres com dor pélvica crônica / Neuronal growing factor expression(NGF), its receptor (trk A) and estrogen and progesterone receptors in pelvicperitoneumin women with chronic pelvic pain

Andrade, Débora Cristiane da Silva 01 July 2009 (has links)
Dor pélvica crônica (DPC) afeta grande númerode mulheres e seu manejo ainda permanece complexo e insatisfatório. Estudos têm demonstrado um envolvimento do fator de crescimento neuronal (FCN) no processo de cronificação da dor. Participação hormonal neste processo também tem sido aventada, visto autores terem demonstrado influência estro/progestacional sobre nociceptores tanto direta quanto indiretamente através da influência exercida sobre os fatores neurotróficos. Foi objetivo deste estudo, verificar a associação entre a expressão do fator de crescimento neuronal (FCN), seu receptor (trk A) e os receptores de estrogênio e progesterona no peritôneo pélvico com a presença de dor pélvica crônica. Para tal foi realizado um estudo transversal incluindo um grupo de 22 mulheres com DPC, 8 com DPC e usuárias de anticoncepcional oral (DPC/ACO) e 7 sem dor. A dor foi analisada pela escala analógica visual (EAV) e questionário de McGill. Foi realizado imunohistoquímica para avaliar FCN e seu receptor trk A, receptores de estrogênio (RE) e progesterona (RP). A expressão de FCN teve media de 5, variando de 0 a 8, no grupo DPC, 5,5 no grupo DPC/ACO variando 3 a 8, e no grupo sem dor de 5 variando de 3 a 8 (p>0,05). A expressão de trk A apresentou media de 6, variandode 3 a 8, no grupo DPC, 6 no grupo DPC/ACO, variando de 4 a 8, e 6 no grupo sem dor variando de 4 a 6 (p>0,05). A expressão do RE apresentou média 4 no grupo DPC, variando de 0 a 8, 3,5 no grupo DPC/ACO variando de 0 a 8, e 7 no grupo sem dor, variando de 6 a 8 (p<0,05). A expressão do RP teve média 6,5 no grupo DPC, variando de 0 a 8, 5 no grupo DPC/ACO, variando de 0 a 7, e 7 no grupo sem dor, variando de 5 a 8 (p>0,05). Nossos resultados sugerem um papel anti-nociceptivo do estrogênio no peritôneo pélvico de mulheres no menacme, não mediado por expressão de FCN ou trk A. / Chronic pelvic pain (CPP) affects a great number of women and its management still remains complex and unsatisfactory. Studies have shown an involvement of the neuronal growing factor (NGF) in the process of permanence of pain. Hormonal participation in this process has also been put forward, as some authors have demonstrated estro/progestational influence under nociceptors direct or indirectly through their influence on neurotrofic factors. This study aimed to verify the association among the expression of neuronal growing factor (NGF), its receptor (TrKA) and the estrogen and progesterone receptors in the pelvic peritoneum with the presence of chronic pelvic pain. A transversal study was carried out including a group of 22 women with CPP, 8 with CPP and users of oral anticonceptional (CPP/OAC) and 7 without pain. The pain was analized by the visual analogic scale (VAS) and McGill\'s questionnaire. Imunehistochemical was performed to evaluate the NGF and its receptor TrKA, estrogen (ER) and progesteron (PR) receptors. The expression of NGF was an average of 5, varying from 0 to 8, in group CPP, 5,5 in group CPP/ OAC varying from 3 to 8, and in the group without pain varying from 3 to 8 (p>0,05). The expression of TrKA presented an average of 6, varying from 3 to 8, in the group CPP, 6 in the group CPP/OAC, varying from 4 to 8, and 6 in the group without pain varying from 4 to 6 (p>0,05). The expression of ER presented an average of 4 in the group CPP, varying from 0 to 8, 3,5 in group CPP/OAC varying from 0 to 8, and 7 in group without pain, varying from 6 to 8 (p<0,05). The expression of PR had an average 6,5 in the group CPP, varying from 0 to 8,5 in the group CPP/OAC, varying from 0 to 7, and 7 in the group without pain, varying from 5 to 8 (p>0,05). Our studies suggest an anti- nociceptive rule of estrogen in the pelvic peritoneum of women in menacme, not mediated by expression of NGF or TrKA.
45

Dor pélvica crônica de origem incerta: caracterização clínico demográfica de 81 doentes / Chronic pelvic pain of uncertain origin. Demographic characterization of a series of 81 patients

Ungaretti Junior, Arthur 06 July 2004 (has links)
Foi caracterizada uma amostra de 81 doentes com dor relevante crônica pélvica de origem indefinida e na ausência de afecções viscerais, segundo a expressão sintomática, aspectos clínicos e síndromes álgicas. A média das idades foi de 48,6 anos. Foram identificadas anormalidades miofasciais pélvica em 55 doentes (67,9%), neuropáticas em 10 (12,3%) e miofasciais e neuropáticas em 16 (19,8%). A descrição verbal da dor e as regiões acometidas pela dor, impactos funcionais, a evidenciação de pontos dolorosos e em gatilhos e os aspectos psicossociais dos doentes foram estabelecidos para melhorar a compreensão da condição clínica dos doentes. Traumatismos decorrentes de traumatismos cirúrgicos estavam relacionados à ocorrência da dor em 36 (44,4%) doentes, sendo dor miofascial em 15 doentes (18,5%), 6 (7,4%) como neuropática e 15 (18,5%) como dor miofascial e neuropática / Eighty-one chronic pelvic pain patients (mean of ages 48.6 years old) without visceral abnormalities and uncertain etiology were characterized according to the symptomatic expression, clinical findings and pain syndromes. It was observed that in 55 patients there was pelvic miofascial pain (67.9%), in 10 patients neuropathic (12.3%) conditions and 16 (19.8%) had miofascial and neuropathic abnormalities. The verbal description of pain, pain aspects as localization, aggravating and improvement factors, functional impact, the occurrence of trigger or tender points and the psychosocial aspects were determined to improve the comprehension of the clinical presentation of the patients. Surgical traumas were related to pain in 26 (32.0%) patients, miofascial pain in 11 (13.6%), neuropathic pain in 5 (6.2%) and miofascial and neuropathic pain in 10 (12.3%)
46

Expressão do fator de crescimento neuronal (FCN), do seu receptor (trk A) e dos receptores de estrogênio e progesterona no peritôneo pélvico em mulheres com dor pélvica crônica / Neuronal growing factor expression(NGF), its receptor (trk A) and estrogen and progesterone receptors in pelvicperitoneumin women with chronic pelvic pain

Débora Cristiane da Silva Andrade 01 July 2009 (has links)
Dor pélvica crônica (DPC) afeta grande númerode mulheres e seu manejo ainda permanece complexo e insatisfatório. Estudos têm demonstrado um envolvimento do fator de crescimento neuronal (FCN) no processo de cronificação da dor. Participação hormonal neste processo também tem sido aventada, visto autores terem demonstrado influência estro/progestacional sobre nociceptores tanto direta quanto indiretamente através da influência exercida sobre os fatores neurotróficos. Foi objetivo deste estudo, verificar a associação entre a expressão do fator de crescimento neuronal (FCN), seu receptor (trk A) e os receptores de estrogênio e progesterona no peritôneo pélvico com a presença de dor pélvica crônica. Para tal foi realizado um estudo transversal incluindo um grupo de 22 mulheres com DPC, 8 com DPC e usuárias de anticoncepcional oral (DPC/ACO) e 7 sem dor. A dor foi analisada pela escala analógica visual (EAV) e questionário de McGill. Foi realizado imunohistoquímica para avaliar FCN e seu receptor trk A, receptores de estrogênio (RE) e progesterona (RP). A expressão de FCN teve media de 5, variando de 0 a 8, no grupo DPC, 5,5 no grupo DPC/ACO variando 3 a 8, e no grupo sem dor de 5 variando de 3 a 8 (p>0,05). A expressão de trk A apresentou media de 6, variandode 3 a 8, no grupo DPC, 6 no grupo DPC/ACO, variando de 4 a 8, e 6 no grupo sem dor variando de 4 a 6 (p>0,05). A expressão do RE apresentou média 4 no grupo DPC, variando de 0 a 8, 3,5 no grupo DPC/ACO variando de 0 a 8, e 7 no grupo sem dor, variando de 6 a 8 (p<0,05). A expressão do RP teve média 6,5 no grupo DPC, variando de 0 a 8, 5 no grupo DPC/ACO, variando de 0 a 7, e 7 no grupo sem dor, variando de 5 a 8 (p>0,05). Nossos resultados sugerem um papel anti-nociceptivo do estrogênio no peritôneo pélvico de mulheres no menacme, não mediado por expressão de FCN ou trk A. / Chronic pelvic pain (CPP) affects a great number of women and its management still remains complex and unsatisfactory. Studies have shown an involvement of the neuronal growing factor (NGF) in the process of permanence of pain. Hormonal participation in this process has also been put forward, as some authors have demonstrated estro/progestational influence under nociceptors direct or indirectly through their influence on neurotrofic factors. This study aimed to verify the association among the expression of neuronal growing factor (NGF), its receptor (TrKA) and the estrogen and progesterone receptors in the pelvic peritoneum with the presence of chronic pelvic pain. A transversal study was carried out including a group of 22 women with CPP, 8 with CPP and users of oral anticonceptional (CPP/OAC) and 7 without pain. The pain was analized by the visual analogic scale (VAS) and McGill\'s questionnaire. Imunehistochemical was performed to evaluate the NGF and its receptor TrKA, estrogen (ER) and progesteron (PR) receptors. The expression of NGF was an average of 5, varying from 0 to 8, in group CPP, 5,5 in group CPP/ OAC varying from 3 to 8, and in the group without pain varying from 3 to 8 (p>0,05). The expression of TrKA presented an average of 6, varying from 3 to 8, in the group CPP, 6 in the group CPP/OAC, varying from 4 to 8, and 6 in the group without pain varying from 4 to 6 (p>0,05). The expression of ER presented an average of 4 in the group CPP, varying from 0 to 8, 3,5 in group CPP/OAC varying from 0 to 8, and 7 in group without pain, varying from 6 to 8 (p<0,05). The expression of PR had an average 6,5 in the group CPP, varying from 0 to 8,5 in the group CPP/OAC, varying from 0 to 7, and 7 in the group without pain, varying from 5 to 8 (p>0,05). Our studies suggest an anti- nociceptive rule of estrogen in the pelvic peritoneum of women in menacme, not mediated by expression of NGF or TrKA.
47

Qualidade de vida de mulheres com dor pélvica crônica / Quality of life of women with chronic pelvic pain

BARCELOS, Priscilla Rodrigues 16 June 2010 (has links)
Made available in DSpace on 2014-07-29T15:29:21Z (GMT). No. of bitstreams: 1 Priscilla Rodrigues Barcelos.pdf: 648226 bytes, checksum: a2133996ea5746c46ce673d1e7bf5785 (MD5) Previous issue date: 2010-06-16 / OBJECTIVES: to compare the quality of life (QOL) of women who have or do not have chronic pelvic pain (CPP) and to investigate the factors associated with QOL in women with CPP. METHODS: a cross-sectional study was performed, in which 30 women with CPP and 20 women without CPP were included. They were premenopausal women aged 18 to 50 years attending the gynecologic outpatient department of a tertiary care university hospital (Hospital das Clínicas, Universidade Federal de Goiás, Brazil). A CPP case was considered when presenting with recurrent or constant pelvic pain of at least six months` duration, unrelated to periods. Women who had been pregnant in the previous year or who had a history of malignant disease were excluded. Sociodemographic and clinical features were assessed. The Medical Outcomes Study 36-item Short-Form Health Survey (SF-36) questionnaire was used to investigate QOL. It provides an eight-scale profile of scores: physical functioning, role-physical, bodily pain, general health, vitality, social functioning, role-emotional and mental health. These eight domains can be summed up in two summary measures: physical component summary (PCS) and mental component summary (MCS). Pain intensity was evaluated using a mechanical visual analogue scale (VAS). Multiple regression analyses was used to compare QOL scores between women with and without CPP and to identify the factors associated with QOL in women with CPP. RESULTS: the mean age of women with and without CPP was 35.2±7.5 and 36±9.3 years, respectively (p=0.77). Women with CPP had a lower monthly family income (p=0.04) and a higher prevalence of dysmenorrhea (87% versus 40%; p<0.01) and depression (30% versus 5%; p=0.04) compared to those without CPP. After adjusting the analyses using potential confounding variables, women with CPP had lower QOL scores in two domains: bodily pain (31 versus 72; p<0.01) and social functioning (56.3 versus 100; p<0.01). Depression was negatively associated with the role-emotional domain (coefficient: -65.185; CI 95% -130.25 to -0.12; p=0.05) and the MCS (coefficient: -23.271; CI 95% -43.8 to -2.74; p=0.03), whereas pain intensity was negatively associated with the bodily pain domain (coefficient: -8.826; CI 95% -13.98 to -3.66; p<0.01) of the QOL of women with CPP. CONCLUSIONS: women with CPP had poorer QOL compared to those without CPP. Depression in women with CPP was associated with lower QOL. Greater pain intensity, as assessed by the mechanical VAS, was also associated with lower QOL among women with CPP. These factors should be considered when managing CPP patients in an attempt to minimize the negative effects they may exert on QOL. / OBJETIVOS: comparar a qualidade de vida (QV) de mulheres com e sem dor pélvica crônica (DPC) e investigar os fatores associados à QV de mulheres com DPC. MÉTODOS: realizou-se um estudo de corte transversal. Foram incluídas mulheres na pré-menopausa, com idade entre 18 e 50 anos, que estavam em seguimento no Ambulatório de Ginecologia do Hospital das Clínicas da Universidade Federal de Goiás. Foi considerado um caso de DPC a presença de dor não cíclica na região pélvica, constante ou intermitente, há pelo menos seis meses. Mulheres que estiveram grávidas nos últimos 12 meses ou com antecedente de neoplasia maligna foram excluídas. Foram incluídas 30 mulheres com DPC e 20 sem DPC. Foram avaliadas características sociodemográficas e clínicas. A QV foi investigada através do questionário SF- 36, que apresenta oito domínios: capacidade funcional, aspectos físicos, dor, estado geral de saúde, vitalidade, aspectos sociais, aspectos emocionais e saúde mental. Estes domínios podem ser resumidos em dois sumários: sumário do componente físico (SCF) e sumário do componente mental (SCM). A intensidade da dor foi pesquisada, aplicando-se a escala visual analógica (EVA) mecânica. Utilizou-se análise de regressão múltipla para comparação dos escores de QV entre mulheres com e sem DPC e para identificação dos fatores associados à QV de mulheres com DPC. RESULTADOS: a média de idade das mulheres com e sem DPC foi de 35,2±7,5 anos e 36±9,3 anos (p=0,77), respectivamente. Mulheres com DPC apresentaram menor renda familiar mensal (p=0,04), e uma maior prevalência de dismenorreia (87% versus 40%; p<0,01) e depressão (30% versus 5%; p=0,04) quando comparadas àquelas sem DPC. Na análise ajustada por potenciais variáveis confundidoras, mulheres com DPC apresentaram menores escores de QV nos domínios dor (31 versus 72; p<0,01) e aspectos sociais (56,3 versus 100; p<0,01). Depressão associouse negativamente ao domínio aspectos emocionais (coeficiente: -65,185; IC 95% -130,25 a -0,12; p=0,05) e ao SCM (coeficiente: -23,271; IC 95% -43,8 a - 2,74; p=0,03), enquanto intensidade da dor relacionou-se negativamente ao domínio dor (coeficiente: -8,826; IC 95% -13,98 a -3,66; p<0,01) da QV de mulheres com DPC. CONCLUSÕES: mulheres com DPC apresentaram pior QV quando comparadas a mulheres sem DPC. O relato de depressão entre mulheres com DPC associou-se a uma pior QV. Quanto maior a intensidade da dor, avaliada através da EVA mecânica, pior a percepção da QV de mulheres com DPC. Dessa forma, esses fatores devem ser considerados na abordagem da mulher com DPC, buscando-se minimizar as repercussões dos mesmos sobre a QV.
48

Dor pélvica crônica de origem incerta: caracterização clínico demográfica de 81 doentes / Chronic pelvic pain of uncertain origin. Demographic characterization of a series of 81 patients

Arthur Ungaretti Junior 06 July 2004 (has links)
Foi caracterizada uma amostra de 81 doentes com dor relevante crônica pélvica de origem indefinida e na ausência de afecções viscerais, segundo a expressão sintomática, aspectos clínicos e síndromes álgicas. A média das idades foi de 48,6 anos. Foram identificadas anormalidades miofasciais pélvica em 55 doentes (67,9%), neuropáticas em 10 (12,3%) e miofasciais e neuropáticas em 16 (19,8%). A descrição verbal da dor e as regiões acometidas pela dor, impactos funcionais, a evidenciação de pontos dolorosos e em gatilhos e os aspectos psicossociais dos doentes foram estabelecidos para melhorar a compreensão da condição clínica dos doentes. Traumatismos decorrentes de traumatismos cirúrgicos estavam relacionados à ocorrência da dor em 36 (44,4%) doentes, sendo dor miofascial em 15 doentes (18,5%), 6 (7,4%) como neuropática e 15 (18,5%) como dor miofascial e neuropática / Eighty-one chronic pelvic pain patients (mean of ages 48.6 years old) without visceral abnormalities and uncertain etiology were characterized according to the symptomatic expression, clinical findings and pain syndromes. It was observed that in 55 patients there was pelvic miofascial pain (67.9%), in 10 patients neuropathic (12.3%) conditions and 16 (19.8%) had miofascial and neuropathic abnormalities. The verbal description of pain, pain aspects as localization, aggravating and improvement factors, functional impact, the occurrence of trigger or tender points and the psychosocial aspects were determined to improve the comprehension of the clinical presentation of the patients. Surgical traumas were related to pain in 26 (32.0%) patients, miofascial pain in 11 (13.6%), neuropathic pain in 5 (6.2%) and miofascial and neuropathic pain in 10 (12.3%)

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