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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
91

Putting the Pieces Together: Exons and piRNAs: A Dissertation

Roy, Christian K. 21 May 2014 (has links)
Analysis of gene expression has undergone a technological revolution. What was impossible 6 years ago is now routine. High-throughput DNA sequencing machines capable of generating hundreds of millions of reads allow, indeed force, a major revision toward the study of the genome’s functional output—the transcriptome. This thesis examines the history of DNA sequencing, measurement of gene expression by sequencing, isoform complexity driven by alternative splicing and mammalian piRNA precursor biogenesis. Examination of these topics is framed around development of a novel RNA-templated DNA-DNA ligation assay (SeqZip) that allows for efficient analysis of abundant, complex, and functional long RNAs. The discussion focuses on the future of transcriptome analysis, development and applications of SeqZip, and challenges presented to biomedical researchers by extremely large and rich datasets.
92

Isolation, molecular characterisation and chromosomal location of repetitive DNA sequences in Brassica / Isolierung, molekulare Charakterisierung und chromosomale Lokalisierung von repetitiven DNA Sequenzen in Brassica

Galvao Bezerra dos Santos, Karla 18 November 2004 (has links)
No description available.
93

Molecular epidemiology of epidemic severe malaria caused by Plasmodium vivax in the state of Amazonas, Brazil /

Santos-Ciminera, Patricia Dantas. Ciminera, Patricia Dantas Santos. Santos, Patricia. January 2005 (has links) (PDF)
Thesis (Ph. D.)--Uniformed Services University of the Health Sciences, 2005. / Typescript (photocopy).
94

Hardwarová akcelerace algoritmu pro hledání podobnosti dvou DNA řetězců / Hardware Acceleration of Algorithms for Approximate String Matching

Nosek, Ondřej January 2007 (has links)
Methods for aproximate string matching of various sequences used in bioinformatics are crucial part of development in this branch. Tasks are of very large time complexity and therefore we want create a hardware platform for acceleration of these computations. Goal of this work is to design a generalized architecture based on FPGA technology, which can work with various types of sequences. Designed acceleration card will use especially dynamic algorithms like Needleman-Wunsch and Smith-Waterman.

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